Regulation of IgE-dependent IL-4 generation by human basophils treated with glucocorticoids

Journal of Immunology

Volumn 158, Issue 11, 1997, Pages 5448-5454

  Schroeder, John T ^a   MacGlashan Jr , Donald W ^a   MacDonald, Susan M ^a   Kagey Sobotka, Anne ^a   Lichtenstein, Lawrence M ^a  

^a JOHNS HOPKINS ASTHMA AND ALLERGY CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOCORTICOID; IMMUNOGLOBULIN E; INTERLEUKIN 4; LYMPHOKINE; MONOCLONAL ANTIBODY; TRANSLATIONALLY CONTROLLED TUMOR PROTEIN, P23; TUMOR MARKER;

ARTICLE; BASOPHIL; BIOSYNTHESIS; DRUG EFFECT; HUMAN; IMMUNOLOGY; POLYMERASE CHAIN REACTION;

ANTIBODIES, MONOCLONAL; BASOPHILS; GLUCOCORTICOIDS; HUMANS; IMMUNOGLOBULIN E; INTERLEUKIN-4; LYMPHOKINES; POLYMERASE CHAIN REACTION; TUMOR MARKERS, BIOLOGICAL;

EID: 0031154587     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Schroeder, J., A. Kagey-Soboika, and L. Lichtenstein. 1995. The role of the basophil in allergic inflammation. Allergy 50:463.
2. Brunner, T., C. H. Heusser, and C. A. Dahinden. 1993. Human peripheral blood basophils primed by interleukin-3 (IL-3) produce IL-4 in response to immunoglobulin E receptor stimulation. J. Exp. Med. 177:605.
3. Arock, M., H. Merle-Beral, B. Dugas, F. Quaaz, L. Le Goff, I. Vouldoukis, J.-M. Mencia-Huerta, C. Schmitt, V. Leblond-Missenard, P. Debre, and M. D. Mossalayi. 1993. IL-4 release by human leukemic and activated normal basophils. J. Immunol. 151:14-11.
4. MacGlashan, D. W., Jr., J. M. White, S. K. Huang, S. J. Ono, J. T. Schroeder, and L. M. Lichlenstein. 1994. Secretion of interleukin-4 from human basophils: the relationship between IL-4 mRNA and protein in resting and stimulated basophils. J. Immunol. 152:3006.
5. Schroeder, J. T., D. W. MacGlashan, Jr., A. Kagey-Sobotka, J. M. White, and L. M. Lichtenstein. 1994. The IgE-dependent IL-4 secretion by human basophils: the relationship between cytokine production and histamine release in mixed leukocyte cultures. J. Immunol. 153:1808.
6. Pipkorn, U., D. Proud, L. M. Lichtenstein, A. Kagey-Sobotka, P. S. Norman, and R. M. Naclerio. 1987. Inhibition of mediator release in allergic rhinitis by pretreatment with topical glucocorticoids. N. Engl. J. Med. 316:1506.
7. Bascom, R., M. Wachs, R. M. Naclerio, U. Pipkorn, S. J. Galli, and L. M. Lichtenstein. 1988. Basophil influx occurs after nasal antigen challenge: effects of topical corticosteroid pretreatment. J. Allergy Clin. Immunol. 81:580.
8. Charlesworth, E., A. Kagey-Sobotka, R. Schleimer, P. Norman, and L. Lichtenstein. 1991. Prednisone inhibits the appearance of inflammatory mediators and the influx of eosinophils and basophils associated with the cutaneous late-phase response to allergen. J. Immunol. 146:671.
9. Schleimer, R. P., L. M. Lichtenstein, and E. Gillespie. 1981. Inhibition of basophil histamine release by anti-inflammatory steroids. Nature 292:454.
10. Cohan, V. L., B. J. Undem, C. C. Fox, N. F. Adkinson, Jr., L. M. Lichtenstein, and R. P. Schleimer. 1989. Dexamethasone does not inhibit the release of mediators from human mast cells residing in airway, intestine, or skin. Am. Rev. Respir. Dis. 140:951.
11. Schwiebert, L., L. Beck, C. Stellato, C. Bickel, B. Bochner, and R. Schleimer. 1996. Glucocorticosteroid inhibition of cytokine production: relevance to antiallergic actions. J. Allergy Clin Immunol. 97(Suppl.):143.
12. MacDonald, S. M., T. Rafner, J. Langdon, and L. M. Lichtenstein. 1995. Molecular identification of an IgE-dependent histamine-releasing factor. Science 269:688.
13. Gilbert, H. S., and L. Ornstein. 1975. Basophil counting with a new staining method using alcian blue. Blood 46:279.
14. Schleimer, R. P., D. W. MacGlashan, Jr., E. Gillespie, and L. M. Lichtenstein. 1982. Inhibition of basophil histamine release by anti-inflammatory steroids. II. Studies on the mechanism of action. J. Immunol. 129:1632.
15. Schroeder, J. T., L. M. Lichtenstein, and S. M. MacDonald. 1996. An IgE-dependent recombinant histamine-releasing factor induces IL-4 secretion from human basophils. J. Exp. Med. 183:1265.
16. Pipkorn, U., D. Proud, L. M. Lichtenstein, R. P. Schleimer, S. P. Peters, N. F. Adkinson, Jr., A. Kagey-Sobotka, P. S. Norman, and R. M. Naclerio. 1987. Effect of short-term systemic glucocorticoid treatment on human nasal mediator release after antigen challenge. J. Clin. Invest. 80:957.
17. Schroeder, J. T., L. M. Lichtenstein, A. Kagey-Sobotka, and D. W. MacGlashan, Jr. 1995. Differential control of basophil histamine and IL-4 secretion with PKC activation. J. Allergy Clin. Immunol. 95:A344.
18. Liu, M., Q. Xiao, L. M. Lichtenstein, and S. Huang. 1994. Prednisone inhibits TH-2-type cytokine gene expression at sites of allergen challenge in subjects with asthma. Am. Rev. Respir. Dis. 149:A944.
19. Masuyama, K., M. R. Jacobson, S. Rak, Q. Meng, R. M. Sudderick, A. B. Kay, O. Lowhagen, Q. Hamid, and S. R. Durham. 1994. Topical glucocorticoid (fluticasone propionate) inhibits cells expressing cytokine mRNA for interleukin-4 in the nasal mucosa in allergen-induced rhinitis. Immunology 82:192.
20. Wu, C., C. Fargeas, T. Nakajima, and G. Delespesse. 1991. Glucocorticoids suppress the production of interleukin-4 by human lymphocytes. Eur. J. Immunol. 21:2645.
21. Schleimer, R. P., S. A. Sterbinsky, J. Kaiser, C. A. Bickel, D. A. Klunk, K. Tomioka, W. Newman, F. W. Luscinskas, M. A. Gimbrone, and B. S. Bochner. 1992. IL-4 induces adherence of human eosinophils and basophils but not neutrophils to endothelium. J. Immunol. 148:1086.
22. Moser, R., and J. Fehr. 1992. IL-4 controls the selective endothelium-driven transmigration of eosinophils from allergic individuals. J. Immunol. 149:1432.
23. Auphan, N., J. DiDonato, C. Rosette, A. Helmberg, and M. Karin. 1995. Immunosuppression by glucocorticoids: inhibition of NF-κB activity through induction of IkB synthesis. Science 270:286.
24. Rao, A. 1994. NF-ATp: a transcription factor required for the co-ordinate induction of several cytokine genes. Immunol. Today 15:274.
25. Prieschl, E. E., V. Gouilleux-Gruait, C. Walker, N. E. Harrer, and T. Baumruker. 1995. A nuclear factor of activated T cell-like transcription factor in mast cells is involved in IL-5 gene regulation after IgE plus antigen stimulation. J. Immunol. 154:6112.