Cryogenic x-ray crystal structure analysis for the complex of scytalone dehydratase of a rice blast fungus and its tight-binding inhibitor, carpropamid: The structural basis of tight-binding inhibition

Biochemistry

Volumn 37, Issue 28, 1998, Pages 9931-9939

  Nakasako, Masayoshi ^a   Motoyama, Takayuki ^b   Kurahashi, Yoshio ^c   Yamaguchi, Isamu ^b  

^a UNIVERSITY OF TOKYO   (Japan)

^b INST OF PHYS AND CHEMICAL RESEARCH   (Japan)

^c Yuki Research Center   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CARPROPAMID; HYDROLYASE; HYDROLYASE INHIBITOR; SCYTALONE DEHYDRATASE; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CRYSTAL STRUCTURE; ENZYME INHIBITOR INTERACTION; FUNGUS; HYDROGEN BOND; HYDROPHOBICITY; MELANOGENESIS; MOLECULAR INTERACTION; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; X RAY CRYSTALLOGRAPHY;

AMIDES; AMINO ACIDS; BINDING, COMPETITIVE; CRYSTALLOGRAPHY, X-RAY; CYCLOPROPANES; FREEZING; FUNGICIDES, INDUSTRIAL; HYDRO-LYASES; MACROMOLECULAR SUBSTANCES; MITOSPORIC FUNGI; MODELS, MOLECULAR; ORYZA SATIVA; PEPTIDE FRAGMENTS; PROTEIN BINDING; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0032516487     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi980321b     Document Type: Article

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