Evaluation of cytochrome P450 mechanism and kinetics using kinetic deuterium isotope effects

Biochemistry

Volumn 37, Issue 19, 1998, Pages 7039-7046

  Higgins, LeeAnn ^a   Bennett, Grace A ^a   Shimoji, Miyuki ^a   Jones, Jeffrey P ^a  

^a UNIVERSITY OF ROCHESTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; DEUTERIUM; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ARTICLE; CELL STRAIN HEPG2; CONTROLLED STUDY; ENERGY TRANSFER; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME MECHANISM; MICHAELIS CONSTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

BINDING, COMPETITIVE; CYTOCHROME P-450 CYP2E1; CYTOCHROME P-450 ENZYME SYSTEM; DEUTERIUM; ENERGY TRANSFER; ISOENZYMES; KINETICS; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; TOLUENE;

ANIMALIA;

EID: 0032510698     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9729864     Document Type: Article

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