A selective analog for the somatostatin sst1-receptor subtype expressed by human tumors

European Journal of Pharmacology

Volumn 345, Issue 1, 1998, Pages 103-110

  Reubi, Jean Claude ^a   Schaer, Jean Claude ^a   Waser, Beatrice ^a   Hoeger, Carl ^b   Rivier, Jean ^b  

^a UNIVERSITY OF BERN   (Switzerland)

^b SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

Author keywords

Peptide receptor; Receptor autoradiography; Somatostatin receptor subtype; Somatostatin sst1 receptor selective analog; Tumors, human

Indexed keywords

RECEPTOR SUBTYPE; SOMATOSTATIN; SOMATOSTATIN DERIVATIVE; SOMATOSTATIN RECEPTOR;

ANIMAL CELL; ARTICLE; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; NONHUMAN; PRIORITY JOURNAL; TUMOR; TUMOR SCINTISCANNING;

AUTORADIOGRAPHY; BINDING, COMPETITIVE; HUMANS; IN SITU HYBRIDIZATION; NEOPLASMS; RECEPTORS, SOMATOSTATIN; SOMATOSTATIN; TUMOR CELLS, CULTURED;

EID: 0032510508     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(97)01618-X     Document Type: Article

References (27)

1. Bruns, C., Weckbecker, G., Raulf, F., Kaupmann, K., Schoeffter, P., Hoyer, D., Lübbert, H., 1994. Molecular pharmacology of somatostatin-receptor subtypes. In: Wiedenmann, B., Kvols, L.K., Arnold, R., Riecken, E. (Eds.), Molecular and Cell Biological Aspects of Gastroenteropancreatic Neuroendocrine Tumor Disease. Ann. NY Acad. Sci., New York, pp. 138-146.
2. Buscail L., Delesque N., Estève J., Saint-Laurent N., Prats H., Clerc P., Robberecht P., Bell G.I., Liebow C., Schally A.V., Vaysse N., Susini C. Stimulation of tyrosine phosphatase and inhibition of cell proliferation by somatostatin analogues: mediation by human somatostatin receptor subtypes SSTR1 and SSTR2. Proc. Natl. Acad. Sci. USA. 91:1994;2315-2319.
3. Buscail L., Estève J., Saint-Laurent N., Bertrand V., Reisine T., O'Carroll A., Bell G.I., Schally A.V., Vaysse N., Susini C. Inhibition of cell proliferation by the somatostatin analogue RC-160 is mediated by somatostatin receptor subtypes SSTR2 and SSTR5 through different mechanisms. Proc. Natl. Acad. Sci. USA. 92:1995;1580-1584.
4. Buscail L., Saint-Laurent N., Chastre E., Vaillant J., Gespach C., Capella G., Kalthoff H., Lluis F., Vaysse N., Susini C. Loss of sst2 somatostatin receptor gene expression in human pancreatic and colorectal cancer. Cancer Res. 56:1996;1823-1827.
5. Greenman Y., Melmed S. Expression of three somatostatin receptor subtypes in pituitary adenomas: Evidence for preferential SSTR5 expression in the mammosomatotroph lineage. J. Clin. Endocrinol. Metab. 79:1994;724-729.
6. Hoyer D., Bell G.I., Berelowitz M., Epelbaum J., Feniuk W., Humphrey P.P.A., O'Carroll A., Patel Y.C., Schönbrunn A., Taylor J.E., Reisine T. Classification and nomenclature of somatostatin receptors. Trends Pharmacol. Sci. 16:1995;86-88.
7. Hukovic N., Panetta R., Kumar U., Patel Y.C. Agonist-dependent regulation of cloned human somatostatin receptor types 1-5 (hSSTR1-5): subtype selective internalization or upregulation. Endocrinology. 137:1996;4046-4049.
8. Krenning E.P., Kwekkeboom D.J., Pauwels S., Kvols L.K., Reubi J.C. Somatostatin receptor scintigraphy. Nucl. Med. Annu. 1995:1995;1-50.
9. Kubota A., Yamada Y., Kagimoto S., Shimatsu A., Imamura M., Tsuda K., Imura H., Seino S., Seino Y. Identification of somatostatin receptor subtypes and an implication of the efficacy of somatostatin analogue SMS 201-995 in treatment of human endocrine tumors. J. Clin. Invest. 93:1994;1321-1325.
10. Lamberts S.W.J., Krenning E.P., Reubi J.C. The role of somatostatin and its analogs in the diagnosis and treatment of tumors. Endocr. Rev. 12:1991;450-482.
11. Liapakis G., Hoeger C., Rivier J., Reisine T. Development of a selective agonist at the somatostatin receptor subtype SSTR1. J. Pharmacol. Exp. Ther. 276:1996;1089-1094.
12. Miller G.M., Alexander J.M., Bikkal H.A., Katznelson L., Zervas N.T., Klibanski A. Somatostatin receptor subtype gene expression in pituitary adenomas. J. Clin. Endocrinol. Metab. 80:1995;1386-1392.
13. Nouel D., Gaudriault G., Houle M., Reisine T., Vincent J., Mazella J., Beaudet A. Differential internalization of somatostatin in COS-7 cells transfected with SST1 and SST2 receptor subtypes: a confocal microscopic study using novel fluorescent somatostatin derivatives. Endocrinology. 138:1997;296-306.
14. Patel Y.C. Molecular pharmacology of somatostatin receptor subtypes. J. Endocrinol. Invest. 20:1997;348-367.
15. Reisine T., Bell G.I. Molecular biology of somatostatin receptors. Endocr. Rev. 16:1995;427-442.
16. Reubi J.C. New specific radioligand for one subpopulation of brain somatostatin receptors. Life Sci. 36:1985;1829-1836.
17. Reubi J.C. Neuropeptide receptors in health and disease: the molecular basis for in vivo imaging. J. Nucl. Med. 36:1995;1825-1835.
18. Reubi J.C., Laissue J.A. Multiple pathways of somatostatin action in neoplastic disease. Trends Pharmacol. Sci. 16:1995;110-115.
19. Reubi J.C., Perrin M.H., Rivier J.E., Vale W. High affinity binding sites for a somatostatin-28 analog in rat brain. Life Sci. 28:1981;2191-2198.
20. Reubi J.C., Horisberger U., Essed C.E., Jeekel J., Klijn J.G.H., Lamberts S.W.J. Absence of somatostatin receptors in human exocrine pancreatic adenocarcinomas. Gastroenterology. 95:1988;760-763.
21. Reubi J.C., Kvols L.K., Waser B., Nagorney D., Heitz P.U., Charboneau J.W., Reading C.C., Moertel C. Detection of somatostatin receptors in surgical and percutaneous needle biopsy samples of carcinoids and islet cell carcinomas. Cancer Res. 50:1990;5969-5977.
22. Reubi J.C., Krenning E., Lamberts S.W.J., Kvols L. In vitro detection of somatostatin receptors in human tumors. Metabolism. 41:1992;104-110.
23. Reubi J.C., Schaer J.C., Waser B., Mengod G. Expression and localization of somatostatin receptor SSTR1, SSTR2 and SSTR3 mRNAs in primary human tumors using in situ hybridization. Cancer Res. 54:1994;3455-3459.
24. Reubi J.C., Waser B., Schaer J.C., Markwalder R. Somatostatin receptors in human prostate and prostate cancer. J. Clin. Endocrinol. Metab. 80:1995;2806-2814.
25. Reubi J.C., Schaer J., Laissue J.A., Waser B. Somatostatin receptors and their subtypes in human tumors and in peritumoral vessels. Metabolism. 45:1996;39-41. Suppl. 1.
26. Schaer J.C., Waser B., Mengod G., Reubi J.C. Somatostatin receptor subtypes sst1, sst2, sst3, and sst5 expression in human pituitary, gastroenteropancreatic and mammary tumors: comparison of mRNA analysis with receptor autoradiography. Int. J. Cancer. 70:1997;530-537.
27. Vikic-Topic S., Raisch K.P., Kvols L.K., Vuk-Pavlovic S. Expression of somatostatin receptor subtypes in breast carcinoma, carcinoid tumor, and renal cell carcinoma. J. Clin. Endocrinol. Metab. 80:1995;2974-2979.