Identification of Ce-AF-6, a novel Caenorhabditis elegans protein, as a putative Ras effector

Gene

Volumn 224, Issue 1-2, 1998, Pages 53-58

  Watari, Yasuhiro ^a   Kariya, Ken Ichi ^a   Shibatohge, Mitsushige ^a   Liao, Yanhong ^a   Hu, Chang Deng ^a   Goshima, Masahiro ^a   Tamada, Masako ^a   Kikuchi, Akira ^b   Kataoka, Tohru ^a  

^a KOBE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b HIROSHIMA UNIV SCHOOL OF MEDICINE   (Japan)

Author keywords

AF 6; LET 60; PDZ domain; RA domain; Two hybrid screening

Indexed keywords

HELMINTH PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; RAF PROTEIN; RAS PROTEIN;

ARTICLE; CAENORHABDITIS ELEGANS; CELL DIFFERENTIATION; CELL GROWTH; DROSOPHILA MELANOGASTER; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CONSERVED SEQUENCE; DROSOPHILA PROTEINS; EVOLUTION, MOLECULAR; KINESIN; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; MYOSINS; RAS PROTEINS; RECEPTORS, NOTCH; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION;

CAENORHABDITIS ELEGANS; DROSOPHILA MELANOGASTER; MAMMALIA; MELANOGASTER; NEMATODA; VERMES;

EID: 0032509189     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(98)00527-7     Document Type: Article

References (29)

1. Akasaka K., Tamada M., Wang F., Kariya K., Shima F., Kikuchi A., Yamamoto M., Shirouzu M., Yokoyama S., Kataoka T. Differential structural requirements for interaction of Ras protein with its distinct downstream effectors. J. Biol. Chem. 271:1996;5353-5360.
2. Altschul S.F., Gish W., Miller W., Myers E.W., Lipman D.J. Basic local alignment search tool. J. Mol. Biol. 215:1990;403-410.
3. Artavanis-Tsakonas S., Matsuno K., Fortini M.E. Notch signaling. Science. 268:1994;225-232.
4. Bartel, P. L., Chien, C.-T., Sternglanz, R., Fields, S., 1993. Cellular interactions in development. In: Hartley, D.A. (Ed.), A Practical Approach. Oxford University Press, Oxford, pp. 153-179.
5. Beitel G.J., Clark S.G., Horvitz H.R. Caenorhabditis elegans ras gene let-60 acts as a switch in the pathway of vulval induction. Nature. 348:1990;503-509.
6. Durfee T., Becherer K., Chen P.-L., Yeh S.-H., Yang Y., Kilburn A.E., Lee W.-H., Elledge S.J. The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit. Genes Dev. 7:1993;555-569.
7. Fehon R.G., Johansen K., Rebay I., Artavanis-Tsakonas S. Complex cellular and subcellular regulation of Notch expression during embryonic and imaginal development of Drosophila: implications for Notch function. J. Cell Biol. 113:1991;657-669.
8. Han M., Aroian R.V., Sternberg P.W. The let-60 locus controls the switch between vulval and nonvulval cell fates in Caenorhabditis elegans. Genetics. 126:1990;899-913.
9. Han M., Sternberg P.W. let-60, a gene that specifies cell fates during C. elegans vulval induction, encodes a ras protein. Cell. 63:1990;921-931.
10. Hu C.-D., Kariya K., Tamada M., Akasaka K., Shirouzu M., Yokoyama S., Kataoka T. Cysteine-rich region of Raf-1 interacts with activator domain of post-translationally modified Ha-Ras. J. Biol. Chem. 270:1995;30274-30277.
11. Katz M.E., McCormick F. Signal transduction from multiple Ras effectors. Curr. Opin. Genet. Dev. 7:1997;75-79.
12. Kornfeld K. Vulval development in Caenorhabditis elegans. Trends Genet. 13:1997;55-61.
13. Krause, M., 1995. Caenorhabditis elegans. In: Epstein, H.F., Shakes, D.C. (Eds.), Modern Biological Analysis of an Organism. Academic Press, San Diego, CA, pp. 513-529.
14. Kuriyama M., Harada N., Kuroda S., Yamamoto T., Nakafuku M., Iwamatsu A., Yamamoto D., Prasad R., Croce C., Canaani E., Kaibuchi K. Identification of AF-6 and canoe as putative targets for Ras. J. Biol. Chem. 271:1996;607-610.
15. Lowy D.R., Willumsen B.M. Function and regulation of ras. Annu. Rev. Biochem. 62:1993;851-891.
16. Mandai K., Nakanishi H., Satoh A., Obaishi H., Wada M., Nishioka H., Itoh M., Mizoguchi A., Aoki T., Fujimoto T., Matsuda Y., Tsukita S., Takai Y. Afadin: A novel actin filament-binding protein with one PDZ domain localized at cadherin-based cell-to-cell adherens junction. J. Cell Biol. 139:1997;517-528.
17. Masuda T., Kariya K., Shinkai M., Okada T., Kataoka T. Protein kinase Byr2 is a target of Ras1 in the fission yeast Schizosaccharomyces pombe. J. Biol. Chem. 270:1995;1979-1982.
18. Miyamoto H., Nihonmatsu I., Kondo S., Ueda R., Togashi S., Hirata K., Ikegami Y., Yamamoto D. canoe encodes a novel protein containing a GLGF/DHR motif and functions with Notch and scabrous in common developmental pathways in Drosophila. Genes Dev. 9:1995;612-625.
19. Prasad R., Gu Y., Alder H., Nakamura T., Canaani O., Saito H., Huebner K., Gale R.P., Nowell P.C., Kuriyama K., Miyazaki Y., Croce C.M., Canaani E. Cloning of the ALL-1 fusion partner, the AF-6 gene, involved in acute myeloid leukemias with the t(6;11) chromosome translocation. Cancer Res. 53:1993;5624-5628.
20. Ponting C.P., Benjamin D.R. A novel family of Ras-binding domains. Trends Biochem. Sci. 21:1996;422-425.
21. Sambrook, J., Fritsch, E.F., Maniatis, T., 1989. Molecular Cloning: A Laboratory Manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
22. Saras J., Heldin C.H. PDZ domains bind carboxy-terminal sequences of target proteins. Trends Biochem. Sci. 21:1996;455-458.
23. Shibatohge M., Kariya K., Liao Y., Hu C.-D., Watari Y., Goshima M., Shima F., Kataoka T. Identification of PLC210, a Caenorhabditis elegans phospholipase C, as a putative effector of Ras. J. Biol. Chem. 273:1998;6218-6222.
24. Sternberg P.W., Horvitz H.R. The combined action of two intercellular signaling pathways specifies three cell fates during vulval induction in C. elegans. Cell. 58:1989;679-693.
25. Toda T., Uno I., Ishikawa T., Powers S., Kataoka T., Broek D., Cameron S., Broach J., Matsumoto K., Wigler M. In yeast, RAS proteins are controlling elements of adenylate cyclase. Cell. 40:1985;27-36.
26. Van Aelst L., Barr M., Marcus S., Polverino A., Wigler M. Complex formation between RAS and RAF and other protein kinases. Proc. Natl. Acad. Sci. USA. 90:1993;6213-6217.
27. Wang J., Suzuki N., Kataoka T. The 70-kilodalton adenylyl cyclase-associating protein is not essential for interaction of Saccharomyces cerevisiae adenylyl cyclase with RAS proteins. Mol. Cell. Biol. 12:1992;4937-4945.
28. White M.A., Nicolette C., Minden A., Polverno A., Van Aelst L., Karin M., Wigler M.H. Multiple Ras functions can contribute to mammalian cell transformation. Cell. 80:1995;533-541.
29. White M.A., Vale T., Camonis J.H., Schaefer E., Wigler M.H. A role for the Ral guanine nucleotide dissociation stimulator in mediating Ras-induced transformation. J. Biol. Chem. 271:1996;16439-16442.