-
1
-
-
0028079647
-
Debrisoquine oxidation genotype and susceptibility to lung cancer
-
Agundez JAG, Martinez C, Ladero JMet al. Debrisoquine oxidation genotype and susceptibility to lung cancer. Clin Pharmacol Ther. 55:1994;10-14.
-
(1994)
Clin Pharmacol Ther
, vol.55
, pp. 10-14
-
-
Agundez, J.A.G.1
Martinez, C.2
Ladero, J.M.3
-
2
-
-
0028964602
-
Association between the oxidative polymorphism and early onset of Parkinson's disease
-
Agundez JAG, Jimemez-Jimenez FJ, Luengo Aet al. Association between the oxidative polymorphism and early onset of Parkinson's disease. Clin Pharmacol Ther. 57:1995;291-293.
-
(1995)
Clin Pharmacol Ther
, vol.57
, pp. 291-293
-
-
Agundez, J.A.G.1
Jimemez-Jimenez, F.J.2
Luengo, A.3
-
3
-
-
0026589459
-
Mutant debrisoquine hydroxylase genes in Parkinson's disease
-
Armstrong M, Daly AK, Cholerton S, Bateman DN, Idle JR Mutant debrisoquine hydroxylase genes in Parkinson's disease. Lancet. 339:1992;1017-1018.
-
(1992)
Lancet
, vol.339
, pp. 1017-1018
-
-
Armstrong, M.1
Daly, A.K.2
Cholerton, S.3
Bateman, D.N.4
Idle, J.R.5
-
4
-
-
0020069715
-
New data on the genetics of Parkinson's disease
-
Barbeau A, Pourcher E New data on the genetics of Parkinson's disease. Can J Neurol Sci. 9:1982;53-60.
-
(1982)
Can J Neurol Sci
, vol.9
, pp. 53-60
-
-
Barbeau, A.1
Pourcher, E.2
-
5
-
-
0022408175
-
Ecogenetics of Parkinson's disease: 4-hydroxylation of debrisoquine
-
Barbeau A, Cloutier T, Roy Met al. Ecogenetics of Parkinson's disease: 4-hydroxylation of debrisoquine. Lancet. 2:1985;1213-1216.
-
(1985)
Lancet
, vol.2
, pp. 1213-1216
-
-
Barbeau, A.1
Cloutier, T.2
Roy, M.3
-
7
-
-
0017148259
-
A general method for isolation of high molecular DNA from eukaryotes
-
Blin N, Stafford DW A general method for isolation of high molecular DNA from eukaryotes. Nucl Acids Res. 3:1976;2303-2308.
-
(1976)
Nucl Acids Res
, vol.3
, pp. 2303-2308
-
-
Blin, N.1
Stafford, D.W.2
-
8
-
-
0029685631
-
Desbrisoquine hydroxylation genotype in familial forms of idiopathic Parkinson's disease
-
Bordet R, Broly F, Destee A, Libersa C Desbrisoquine hydroxylation genotype in familial forms of idiopathic Parkinson's disease. Adv Neurol. 69:1996;97-100.
-
(1996)
Adv Neurol
, vol.69
, pp. 97-100
-
-
Bordet, R.1
Broly, F.2
Destee, A.3
Libersa, C.4
-
9
-
-
0028806579
-
A nonsense mutation in the cytochrome P450 CYP2D6 gene identified in a Caucasian with an enzyme deficiency
-
Broly F, Marez D, Lo-uidice JMet al. A nonsense mutation in the cytochrome P450 CYP2D6 gene identified in a Caucasian with an enzyme deficiency. Hum Genet. 96:1995;601-603.
-
(1995)
Hum Genet
, vol.96
, pp. 601-603
-
-
Broly, F.1
Marez, D.2
Lo-Uidice, J.M.3
-
10
-
-
0010467816
-
A new CYP2D6 mutation associated with Parkinson's disease in American Caucasians
-
Chan P, Tanner CM, Langston JW A new CYP2D6 mutation associated with Parkinson's disease in American Caucasians. Movement Disord. 10:1995;689.
-
(1995)
Movement Disord
, vol.10
, pp. 689
-
-
Chan, P.1
Tanner, C.M.2
Langston, J.W.3
-
11
-
-
0010506383
-
Debrisoquine metabolism in Parkinson's disease [abstract]
-
Comella CL, Tanner CM, Goetz CGet al. Debrisoquine metabolism in Parkinson's disease [abstract]. Neurology. 37(Suppl 1):1987;261-262.
-
(1987)
Neurology
, vol.37
, Issue.SUPPL. 1
, pp. 261-262
-
-
Comella, C.L.1
Tanner, C.M.2
Goetz, C.G.3
-
12
-
-
0002240298
-
On the effects of black oxide of manganese when inhaled into the lungs
-
Couper J On the effects of black oxide of manganese when inhaled into the lungs. Br Ann Med Pharm. 1:1837;41-42.
-
(1837)
Br Ann Med Pharm
, vol.1
, pp. 41-42
-
-
Couper, J.1
-
13
-
-
0026610576
-
Analysis of the CYP2D6 gene in relation to debrisoquine and desipramine hydroxylation in a Swedish population
-
Dahl ML, Johansson I, Palmertz MP, Ingelman-Sundberg M, Sjoqvist F Analysis of the CYP2D6 gene in relation to debrisoquine and desipramine hydroxylation in a Swedish population. Clin Pharmacol Ther. 51:1992;12-17.
-
(1992)
Clin Pharmacol Ther
, vol.51
, pp. 12-17
-
-
Dahl, M.L.1
Johansson, I.2
Palmertz, M.P.3
Ingelman-Sundberg, M.4
Sjoqvist, F.5
-
14
-
-
0028929652
-
An inactive cytochrome P450 CYP2D6 allele containing a deletion and a base substitution
-
Daly AK, Leathart JBS, London SJ, Idle JR An inactive cytochrome P450 CYP2D6 allele containing a deletion and a base substitution. Hum Genet. 95:1995;337-341.
-
(1995)
Hum Genet
, vol.95
, pp. 337-341
-
-
Daly, A.K.1
Leathart, J.B.S.2
London, S.J.3
Idle, J.R.4
-
15
-
-
0028355764
-
Interpretation of a simple PCR analysis of the CYP2D6(A) and CYP2D6(B) null alleles associated with the debrisoquine/sparteine genetic polymorphism
-
Douglas AM, Atchison BA, Somogyi AA, Drummer OH Interpretation of a simple PCR analysis of the CYP2D6(A) and CYP2D6(B) null alleles associated with the debrisoquine/sparteine genetic polymorphism. Pharmacogenetics. 4:1994;154-158.
-
(1994)
Pharmacogenetics
, vol.4
, pp. 154-158
-
-
Douglas, A.M.1
Atchison, B.A.2
Somogyi, A.A.3
Drummer, O.H.4
-
16
-
-
0018900001
-
A family and population study of the genetic polymorphism of debrisoquine oxidation in a white British population
-
Evans DA, Mahgoub A, Sloan TP, Idle JR, Smith RL A family and population study of the genetic polymorphism of debrisoquine oxidation in a white British population. J Med Genet. 17:1980;102-105.
-
(1980)
J Med Genet
, vol.17
, pp. 102-105
-
-
Evans, D.A.1
Mahgoub, A.2
Sloan, T.P.3
Idle, J.R.4
Smith, R.L.5
-
17
-
-
0026361512
-
Concordance of P450 2D6 (debrisoquine hydroxylase) phenotype and genotype: Inability of dextromethorphan metabolic ratio to discriminate reliably heterozygous and homozygous extensive metabolizers
-
Evans WE, Relling MV Concordance of P450 2D6 (debrisoquine hydroxylase) phenotype and genotype: inability of dextromethorphan metabolic ratio to discriminate reliably heterozygous and homozygous extensive metabolizers. Pharmacogenetics. 1:1991;143-148.
-
(1991)
Pharmacogenetics
, vol.1
, pp. 143-148
-
-
Evans, W.E.1
Relling, M.V.2
-
18
-
-
0028109283
-
A missense mutation in exon 6 of the CYP2D6 gene leading to a histidine 324 to proline exchange is associated with the poor metabolizer phenotype of sparteine
-
Evert B, Griese EU, Eichelbaum M A missense mutation in exon 6 of the CYP2D6 gene leading to a histidine 324 to proline exchange is associated with the poor metabolizer phenotype of sparteine. Naunyn Schmiedebergs Arch Pharmacol. 350:1994;434-439.
-
(1994)
Naunyn Schmiedebergs Arch Pharmacol
, vol.350
, pp. 434-439
-
-
Evert, B.1
Griese, E.U.2
Eichelbaum, M.3
-
19
-
-
0028046321
-
Cloning and sequencing of a new non-functional CYP2D6 allele: Deletion of T1795 in exon 3 generates a premature stop codon
-
Evert B, Griese EU, Eichelbaum M Cloning and sequencing of a new non-functional CYP2D6 allele: deletion of T1795 in exon 3 generates a premature stop codon. Pharmacogenetics. 4:1994;271-274.
-
(1994)
Pharmacogenetics
, vol.4
, pp. 271-274
-
-
Evert, B.1
Griese, E.U.2
Eichelbaum, M.3
-
20
-
-
0028124654
-
Genetic linkage studies in autosomal dominant Parkinsonism: Evaluation of seven candidate genes
-
Gasser T, Wszolek ZK, Trofatter Jet al. Genetic linkage studies in autosomal dominant Parkinsonism: evaluation of seven candidate genes. Ann Neurol. 36:1994;387-394.
-
(1994)
Ann Neurol
, vol.36
, pp. 387-394
-
-
Gasser, T.1
Wszolek, Z.K.2
Trofatter, J.3
-
21
-
-
17144473115
-
Genetic linkage studies in autosomal dominantly inherited L-DOPA responsive parkinsonism
-
Gasser T, Wszolek Z, Supala Aet al. Genetic linkage studies in autosomal dominantly inherited L-DOPA responsive parkinsonism. Adv Neurol. 69:1996;87-95.
-
(1996)
Adv Neurol
, vol.69
, pp. 87-95
-
-
Gasser, T.1
Wszolek, Z.2
Supala, A.3
-
22
-
-
0025243460
-
1934→A base change in intron 3 of a mutant CYP2D6 allele results in an aberrant 3′ splice recognition site
-
1934→A base change in intron 3 of a mutant CYP2D6 allele results in an aberrant 3′ splice recognition site. Am J Hum Genet. 47:1990;994-1001.
-
(1990)
Am J Hum Genet
, vol.47
, pp. 994-1001
-
-
Hanioka, H.1
Kimura, S.2
Meyer, U.A.3
Gonzalez, F.J.4
-
23
-
-
0029844003
-
Inhibition of neuronal nitric oxide synthase prevents MPTP-induced Parkinsonism in baboons
-
Hantraye P, Brouillet E, Ferrante Ret al. Inhibition of neuronal nitric oxide synthase prevents MPTP-induced Parkinsonism in baboons. Nature Med. 2:1996;1017-1021.
-
(1996)
Nature Med
, vol.2
, pp. 1017-1021
-
-
Hantraye, P.1
Brouillet, E.2
Ferrante, R.3
-
24
-
-
0025080352
-
Genotyping of poor metabolizers of debrisoquine by allele-specific PCR amplification
-
Heim M, Meyer UA Genotyping of poor metabolizers of debrisoquine by allele-specific PCR amplification. Lancet. 336:1990;529-532.
-
(1990)
Lancet
, vol.336
, pp. 529-532
-
-
Heim, M.1
Meyer, U.A.2
-
25
-
-
0029691129
-
The molecular biology of xenobiotic enzymes and the predisposition to idiopathic Parkinson's disease
-
Ho SL, McCann KP, Bennett Pet al. The molecular biology of xenobiotic enzymes and the predisposition to idiopathic Parkinson's disease. Adv Neurol. 69:1996;53-60.
-
(1996)
Adv Neurol
, vol.69
, pp. 53-60
-
-
Ho, S.L.1
McCann, K.P.2
Bennett, P.3
-
26
-
-
0025036544
-
Multiple mutations of the human cytochrome P450IID6 gene (CYP2D6) in poor metabolizers of debrisoquine. Study of the functional significance of individual mutations by expression of chimeric genes
-
Kagimoto M, Heim M, Kagimoto K, Zeugin T, Meyer UA Multiple mutations of the human cytochrome P450IID6 gene (CYP2D6) in poor metabolizers of debrisoquine. Study of the functional significance of individual mutations by expression of chimeric genes. J Biol Chem. 265:1990;17209-17214.
-
(1990)
J Biol Chem
, vol.265
, pp. 17209-17214
-
-
Kagimoto, M.1
Heim, M.2
Kagimoto, K.3
Zeugin, T.4
Meyer, U.A.5
-
28
-
-
0027330416
-
Variant cytochrome P450 CYP2D6 allelic frequencies in Parkinson's disease
-
Kurth MC, Kurth JH Variant cytochrome P450 CYP2D6 allelic frequencies in Parkinson's disease. Am J Med Genet. 48:1993;166-168.
-
(1993)
Am J Med Genet
, vol.48
, pp. 166-168
-
-
Kurth, M.C.1
Kurth, J.H.2
-
29
-
-
0020680904
-
Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis
-
Langston JW, Ballard PA, Tetrud JW, Irwin I Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis. Science. 219:1984;979-980.
-
(1984)
Science
, vol.219
, pp. 979-980
-
-
Langston, J.W.1
Ballard, P.A.2
Tetrud, J.W.3
Irwin, I.4
-
30
-
-
0026667928
-
Debrisoquine metabolism in Chinese patients with Alzheimer's and Parkinson's diseases
-
Liu TAU, Chi CW, Yang JC, Cheng SC, Liu HC Debrisoquine metabolism in Chinese patients with Alzheimer's and Parkinson's diseases. Mol Chem Neuropathol. 17:1992;31-37.
-
(1992)
Mol Chem Neuropathol
, vol.17
, pp. 31-37
-
-
Liu, T.A.U.1
Chi, C.W.2
Yang, J.C.3
Cheng, S.C.4
Liu, H.C.5
-
31
-
-
0027755278
-
Debrisoquine and mephenytoin hydroxylation phenotypes and CYP2D6 genotype in patients treated with neuroleptic and antidepressant agents
-
Llerena A, Heraiz AG, Cobaleda J, Johansson I, Dahl ML Debrisoquine and mephenytoin hydroxylation phenotypes and CYP2D6 genotype in patients treated with neuroleptic and antidepressant agents. Clin Pharmacol Ther. 54:1993;606-611.
-
(1993)
Clin Pharmacol Ther
, vol.54
, pp. 606-611
-
-
Llerena, A.1
Heraiz, A.G.2
Cobaleda, J.3
Johansson, I.4
Dahl, M.L.5
-
32
-
-
84920227522
-
Low frequency of slow debrisoquine hydroxylation in a native Chinese population
-
Lou YC, Ying L, Bertilsson L, Sjoqvist F Low frequency of slow debrisoquine hydroxylation in a native Chinese population. Lancet. 2:1987;852-853.
-
(1987)
Lancet
, vol.2
, pp. 852-853
-
-
Lou, Y.C.1
Ying, L.2
Bertilsson, L.3
Sjoqvist, F.4
-
33
-
-
0028826569
-
A novel CYP2D6 allele with an abolished splice recognition site associated with the poor metabolizer phenotype
-
Marez D, Sabbagh N, Legrand Met al. A novel CYP2D6 allele with an abolished splice recognition site associated with the poor metabolizer phenotype. Pharmacogenetics. 5:1995;305-311.
-
(1995)
Pharmacogenetics
, vol.5
, pp. 305-311
-
-
Marez, D.1
Sabbagh, N.2
Legrand, M.3
-
35
-
-
0027989294
-
Debrisoquine hydroxylase gene polymorphism in familial Parkinson's disease
-
Plante-Bordeneuve V, Davis MB, Maraganore DM, Marsden CD, Harding AE Debrisoquine hydroxylase gene polymorphism in familial Parkinson's disease. J Neurol Neurosurg Psychiatry. 57:1994;911-913.
-
(1994)
J Neurol Neurosurg Psychiatry
, vol.57
, pp. 911-913
-
-
Plante-Bordeneuve, V.1
Davis, M.B.2
Maraganore, D.M.3
Marsden, C.D.4
Harding, A.E.5
-
36
-
-
0030056697
-
CYP2D6 allelic frequencies in young-onset Parkinson's disease
-
Sandy MS, Armstrong M, Tanner CMet al. CYP2D6 allelic frequencies in young-onset Parkinson's disease. Neurology. 47:1996;225-230.
-
(1996)
Neurology
, vol.47
, pp. 225-230
-
-
Sandy, M.S.1
Armstrong, M.2
Tanner, C.M.3
-
37
-
-
0028305240
-
Identification of a new variant CYP2D6 allele with a single base deletion in exon 3 and its association with the poor metabolizer phenotype
-
Saxena R, Shaw GL, Relling MVet al. Identification of a new variant CYP2D6 allele with a single base deletion in exon 3 and its association with the poor metabolizer phenotype. Hum Mol Genet. 3:1994;923-926.
-
(1994)
Hum Mol Genet
, vol.3
, pp. 923-926
-
-
Saxena, R.1
Shaw, G.L.2
Relling, M.V.3
-
38
-
-
0026747176
-
Debrisoquine hydroxylase gene polymorphism and susceptibility to Parkinson's disease
-
Smith CAD, Gough AC, Leigh PNet al. Debrisoquine hydroxylase gene polymorphism and susceptibility to Parkinson's disease. Lancet. 339:1992;1375-1377.
-
(1992)
Lancet
, vol.339
, pp. 1375-1377
-
-
Smith, C.A.D.1
Gough, A.C.2
Leigh, P.N.3
-
39
-
-
0026781283
-
Debrisoquine hydroxylation in Parkinson's disease
-
Steiger MJ, Lledo P, Quinn NPet al. Debrisoquine hydroxylation in Parkinson's disease. Acta Neurol Scand. 86:1992;159-164.
-
(1992)
Acta Neurol Scand
, vol.86
, pp. 159-164
-
-
Steiger, M.J.1
Lledo, P.2
Quinn, N.P.3
-
40
-
-
0023701452
-
Polymorphic debrisoquine hydroxylation in 757 Swedish subjects
-
Steiner E, Bertilsson L, Sawe J, Bertling I, Sjoqvist F Polymorphic debrisoquine hydroxylation in 757 Swedish subjects. Clin Pharmacol Ther. 44:1988;431-435.
-
(1988)
Clin Pharmacol Ther
, vol.44
, pp. 431-435
-
-
Steiner, E.1
Bertilsson, L.2
Sawe, J.3
Bertling, I.4
Sjoqvist, F.5
-
41
-
-
0027200680
-
A novel cytochrome P-450IID6 mutant gene association with Parkinson's disease
-
Tsuneoka Y, Matsuo Y, Iwahashi K, Takeuchi H, Ichikawa Y A novel cytochrome P-450IID6 mutant gene association with Parkinson's disease. J Biochem. 114:1993;263-266.
-
(1993)
J Biochem
, vol.114
, pp. 263-266
-
-
Tsuneoka, Y.1
Matsuo, Y.2
Iwahashi, K.3
Takeuchi, H.4
Ichikawa, Y.5
-
42
-
-
0028296416
-
Parkinson's disease in Kin-Hu Kinmen: A community survey by neurologists
-
Wang SJ, Fuh JL, Liu CYet al. Parkinson's disease in Kin-Hu Kinmen: a community survey by neurologists. Neuroepidemiology. 13:1994;69-74.
-
(1994)
Neuroepidemiology
, vol.13
, pp. 69-74
-
-
Wang, S.J.1
Fuh, J.L.2
Liu, C.Y.3
-
43
-
-
0027418152
-
Molecular basis of genetic variation in debrisoquine hydroxylation in Chinese subjects: Polymorphism in RFLP and DNA sequence of CYP2D6
-
Wang SL, Huang JD, Lai MD, Liu BH, Lai ML Molecular basis of genetic variation in debrisoquine hydroxylation in Chinese subjects: polymorphism in RFLP and DNA sequence of CYP2D6. Clin Pharmacol Ther. 53:1993;410-418.
-
(1993)
Clin Pharmacol Ther
, vol.53
, pp. 410-418
-
-
Wang, S.L.1
Huang, J.D.2
Lai, M.D.3
Liu, B.H.4
Lai, M.L.5
|