Primer unit specificity in rifamycin biosynthesis principally resides in the later stages of the biosynthetic pathway [12]

Journal of the American Chemical Society

Volumn 120, Issue 5, 1998, Pages 1092-1093

  Hunziker, D ^a   Yu, T W ^a   Hutchinson, C R ^a   Floss, H G ^a   Khosla, C ^a  

^a Stanford University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RIFAMYCIN;

BIOSYNTHESIS; DRUG SYNTHESIS; LETTER; REACTION ANALYSIS;

EID: 0032506939     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja9736368     Document Type: Letter

References (17)

1. O'Hagan, D. O. The Polyketide Metabolites; Horwood: Chichester, U.K., 1991.
2. Cortes, J.; Haydock, S. F.; Roberts, G. A.; Bevitt, D. J.; Leadlay, P. F. Nature 1990, 348, 176-178.
3. Donadio, S.; Staver, M. J.; McAlpine, J. B.; Swanson, S. J.; Katz, L. Science 1991, 252, 675-679.
4. Former name: Nocardia mediterranei.
5. (a) Tang, L.; Yeow, J. Y.; Hutchinson, C. R. Unpublished results.
6. (b) Kim, C.-G.; August, P. R.; Yu, T.-W.; Mueller, R.; Mueller, M.; Ning, S.; Hofmann, D.; Leistner, E.; Floss, H. G. The 10th International Symposium on Biology of Actinomycetes ISBA 97; Beijing, China, May 27-30, 1997; abstract no. 2S9.
7. Ghisalba, O.; Furrer, H.; Richter, W.; Moss, S. J Antibiot. 1981, 34, 58-63.
8. Ghisalba, O.; Traxler, P.; Nuesch, J. J. Antibiot. 1978, 31, 1124-1131.
9. Anderson, M. G.; Monypenny, D.; Rickards, R. W.; Rothschild, J. M. J. Chem. Soc., Chem. Commun. 1989, 311-313.
10. Kim, C.-G.; Yu, T.-W.; Fryhle, C.; Handa, S.; Floss, H. G. Submitted for publication.
11. (a) Ghisalba, O.; Nuesch, J. J. Antibiot. 1981, 34, 64-71.
12. (b) Traxler, P.; Ghisalba, O. J. Antibiot. 1982, 35, 1361-1982.
13. (c) Becker, A. M.; Herlt, A. J.; Hilton, G. L.; Kibby, J. J.; Rickards, R. W. J. Antibiot. 1983, 36, 1323-1328.
14. For the synthesis of 2, see: Herlt, A. J.; Kibby, J. J.; Rickards, R. W. Aust. J. Chem. 1981, 34, 1319-1324.
15. Jacobsen, J. R.; Hutchinson, C. R.; Cane, D. A.; Khosla, C. Science 1997, 277, 367-369.
16. Dutton, C. J.; Gibson, S. P.; Goudie, A. C.; Holdom, K. S.; Pacey, M. S.; Ruddock, J. C.; Bu'Lock, J. D.; Richards, M. K. J. Antibiot. 1991, 44, 357-365.
17. Rinehart, K. L., Jr. Pure Appl. Chem. 1977, 49, 1361-1384.