The effect of hypothermia on the expression of neurotrophin mRNA in the hippocampus following transient cerebral ischemia in the rat

Molecular Brain Research

Volumn 63, Issue 1, 1998, Pages 163-173

  Boris Möller, Fredrik ^a,b   Kamme, Fredrik ^a   Wieloch, Tadeusz ^a  

^a LUND UNIVERSITY   (Sweden)

^b LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Brain; Gene expression; Hypothermia; Ischemia; Neurotrophin; Protection

Indexed keywords

NEUROTROPHIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; CRYOANESTHESIA; DENTATE GYRUS; HIPPOCAMPUS; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TRANSIENT ISCHEMIC ATTACK;

ANIMALS; BLOTTING, NORTHERN; BRAIN CHEMISTRY; BRAIN-DERIVED NEUROTROPHIC FACTOR; GENE EXPRESSION; HIPPOCAMPUS; HYPOTHERMIA, INDUCED; IN SITU HYBRIDIZATION; ISCHEMIC ATTACK, TRANSIENT; MALE; NERVE GROWTH FACTORS; NEUROPROTECTIVE AGENTS; NEUROTROPHIN 3; RATS; RATS, WISTAR; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, CILIARY NEUROTROPHIC FACTOR; RECEPTORS, NERVE GROWTH FACTOR; RNA, MESSENGER;

ANIMALIA; HIPPOCAMPUS HIPPOCAMPUS;

EID: 0032506612     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(98)00286-1     Document Type: Article

References (60)

1. Andersen P., Moser E.I. Brain temperature and hippocampal function. Hippocampus. 5:1995;491-498.
2. Bading H., Ginty D.D., Greenberg M.E. Regulation of gene expression in hippocampal neurons by distinct calcium signaling pathways. Science. 260:1993;181-186.
3. Barde Y.A. Neurotrophins: a family of proteins supporting the survival of neurons. Prog. Clin. Biol. Res. 390:1994;45-56.
4. Beck T., Lindholm D., Castren E., Wree A. Brain-derived neurotrophic factor protects against ischemic cell damage in rat hippocampus. J. Cereb. Blood Flow Metab. 14:1994;689-692.
5. Bengzon J., Soderstrom S., Kokaia Z., Kokaia M., Ernfors P., Persson H., Ebendal T., Lindvall O. Widespread increase of nerve growth factor protein in the rat forebrain after kindling-induced seizures. Brain Res. 587:1992;338-342.
6. Bergstedt K., Hu B.R., Wieloch T. Post-ischemic changes in protein synthesis in the rat brain: effects of hypothermia. Exp. Brain Res. 95:1993;91-99.
7. Busto R., Dietrich W.D., Globus M.Y., Valdes I., Scheinberg P., Ginsberg M.D. Small differences in intraischemic brain temperature critically determine the extent of ischemic neuronal injury. J. Cereb. Blood Flow Metab. 7:1987;729-738.
8. Busto R., Globus M.Y., Dietrich W.D., Martinez E., Valdes I., Ginsberg M.D. Effect of mild hypothermia on ischemia-induced release of neurotransmitters and free fatty acids in rat brain. Stroke. 20:1989;904-910.
9. Busto R., Globus M.Y., Neary J.T., Ginsberg M.D. Regional alterations of protein kinase C activity following transient cerebral ischemia: effects of intraischemic brain temperature modulation. J. Neurochem. 63:1994;1095-1103.
10. Cardell M., Boris-Möller F., Wieloch T. Hypothermia prevents the ischemia-induced translocation and inhibition of protein kinase C in the rat striatum. J. Neurochem. 57:1991;1814-1817.
11. Carlsson C., Hägerdal M., Siesjö B.K. Protective effect of hypothermia in cerebral oxygen deficiency caused by arterial hypoxia. Anesthesiology. 44:1976;27-35.
12. Chomczynski P., Sacchi N.I. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:1987;156-159.
13. D'Mello S.R., Heinrich G. Structural and functional identification of regulatory regions and cis elements surrounding the nerve growth factor gene promoter. Brain Res. Mol. Brain Res. 11:1991;255-264.
14. Ernfors P., Ibanez C.F., Ebendal T., Olson L., Persson H. Molecular cloning and neurotrophic activities of a protein with structural similarities to nerve growth factor: developmental and topographical expression in the brain. Proc. Natl. Acad. Sci. U.S.A. 87:1990;5454-5458.
15. Falkenberg T., Ernfors P., Persson H., Lindefors N. Cortical transynaptic activation of tyrosine kinase receptor trkB messenger RNA expression in rat hippocampus. Neuroscience. 51:1992;883-889.
16. Fernyhough P., Maeda K., Tomlinson D.R. Brain-derived neurotrophic factor mRNA levels are up-regulated in hindlimb skeletal muscle of diabetic rats: effect of denervation. Exp. Neurol. 141:1996;297-303.
17. Hansen A.J. Effect of anoxia on ion distribution in the brain. Physiol. Rev. 65:1985;101-148.
18. Hengerer B., Lindholm D., Heumann R., Ruther U., Wagner E.F., Thoenen H. Lesion-induced increase in nerve growth factor mRNA is mediated by c-fos. Proc. Natl. Acad. Sci. U.S.A. 87:1990;3899-3903.
19. Hu B.R., Wieloch T. Changes in tyrosine phosphorylation in neocortex following transient cerebral ischaemia. NeuroReport. 4:1993;219-222.
20. 2+/calmodulin-dependent protein kinase II to synaptic junctions in the vulnerable hippocampal CA1 region following transient ischemia. J. Neurochem. 64:1995;277-284.
21. Kamme F., Campbell K., Wieloch T. Biphasic expression of the fos and jun families of transcription factors following transient forebrain ischaemia in the rat. Effect of hypothermia. Eur. J. Neurosci. 7:1995;2007-2016.
22. Kang H., Schuman E.M. A requirement for local protein synthesis in neurotrophin-induced hippocampal synaptic plasticity. Science. 273:1996;1402-1406.
23. Kang H.J., Schuman E.M. Neurotrophin-induced modulation of synaptic transmission in the adult hippocampus. J. Physiol. (Paris). 89:1995;11-22.
24. Kiessling M., Stumm G., Xie Y., Herdegen T., Aguzzi A., Bravo R., Gass P. Differential transcription and translation of immediate early genes in the gerbil hippocampus after transient global ischemia. J. Cereb. Blood Flow Metab. 13:1993;914-924.
25. Kil H.Y., Zhang J., Piantadosi C.A. Brain temperature alters hydroxyl radical production during cerebral ischemia/reperfusion in rats. J. Cereb. Blood Flow Metab. 16:1996;100-106.
26. Klein R., Parada L.F., Coulier F., Barbacid M. trkB, A novel tyrosine protein kinase receptor expressed during mouse neural development. EMBO J. 8:1989;3701-3709.
27. Koh J.Y., Gwag B.J., Lobner D., Choi D.W. Potentiated necrosis of cultured cortical neurons by neurotrophins. Science. 268:1995;573-575.
28. Kokaia Z., Gidö G., Ringstedt T., Bengzon J., Kokaia M., Siesjö B.K., Persson H., Lindvall O. Rapid increase of BDNF mRNA levels in cortical neurons following spreading depression: regulation by glutamatergic mechanisms independent of seizure activity. Brain Res. Mol. Brain Res. 19:1993;277-286.
29. Kokaia Z., Zhao Q., Kokaia M., Elmer E., Metsis M., Smith M.L., Siesjö B.K., Lindvall O. Regulation of brain-derived neurotrophic factor gene expression after transient middle cerebral artery occlusion with and without brain damage. Exp. Neurol. 136:1995;73-88.
30. Kristian T., Katsura K., Siesjö B.K. The influence of moderate hypothermia on cellular calcium uptake in complete ischemia: implications for the excitotoxic hypothesis. Acta Physiol. Scand. 146:1992;531-532.
31. Kumar K., Wu X., Evans A.T. Expression of c-fos and fos-B proteins following transient forebrain ischemia: effect of hypothermia. Brain Res. Mol. Brain Res. 42:1996;337-343.
32. Lanier W.L. Cerebral metabolic rate and hypothermia: their relationship with ischemic neurologic injury. J. Neurosurg. Anesthesiol. 7:1995;216-221.
33. Leonov Y., Sterz F., Safar P., Radovsky A., Oku K., Tisherman S., Stezoski S.W. Mild cerebral hypothermia during and after cardiac arrest improves neurologic outcome in dogs. J. Cereb. Blood Flow Metab. 10:1990;57-70.
34. Levine E.S., Dreyfus C.F., Black I.B., Plummer M.R. Brain-derived neurotrophic factor rapidly enhances synaptic transmission in hippocampal neurons via post-synaptic tyrosine kinase receptors. Proc. Natl. Acad. Sci. U.S.A. 92:1995;8074-8077.
35. Lindholm D., Carroll P., Tzimagiogis G., Thoenen H. Autocrine-paracrine regulation of hippocampal neuron survival by IGF-1 and the neurotrophins BDNF, NT-3 and NT-4. Eur. J. Neurosci. 8:1996;1452-1460.
36. Lindholm D., da Penha Berzaghi M., Cooper J., Thoenen H., Castren E. Brain-derived neurotrophic factor and neurotrophin-4 increase neurotrophin-3 expression in the rat hippocampus. Int. J. Dev. Neurosci. 12:1994;745-751.
37. Lindvall O., Ernfors P., Bengzon J., Kokaia Z., Smith M.L., Siesjö B.K., Persson H. Differential regulation of mRNAs for nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 in the adult rat brain following cerebral ischemia and hypoglycemic coma. Proc. Natl. Acad. Sci. U.S.A. 89:1992;648-652.
38. Maisonpierre P.C., Le Beau M.M., Espinosa R.d., Ip N.Y., Belluscio L., de la Monte S.M., Squinto S., Furth M.E., Yancopoulos G.D. Human and rat brain-derived neurotrophic factor and neurotrophin-3: gene structures, distributions, and chromosomal localizations. Genomics. 10:1991;558-568.
39. Meberg P.J., Kinney W.R., Valcourt E.G., Routtenberg A. Gene expression of the transcription factor NF-kappa B in hippocampus: regulation by synaptic activity. Brain Res. Mol. Brain Res. 38:1996;179-190.
40. Merlio J.P., Ernfors P., Kokaia Z., Middlemas D.S., Bengzon J., Kokaia M., Smith M.L., Siesjö B.K., Hunter T., Lindvall O.et al. Increased production of the TrkB protein tyrosine kinase receptor after brain insults. Neuron. 10:1993;151-164.
41. Middlemas D.S., Lindberg R.A., Hunter T. trkB, A neural receptor protein-tyrosine kinase: evidence for a full-length and two truncated receptors. Mol. Cell Biol. 11:1991;143-153.
42. 14C plastic standards for quantitative autoradiography using LKB Ultrofilm or Amersham Hyperfilm Neurosci. Lett. 121:1991;1-2.
43. Minamisawa H., Nordstrom C.H., Smith M.L., Siesjö B.K. The influence of mild body and brain hypothermia on ischemic brain damage. J. Cereb. Blood Flow Metab. 10:1990;365-374.
44. Nicoletti F., Bruno V., Copani A., Casabona G., Knopfel T. Metabotropic glutamate receptors: a new target for the therapy of neurodegenerative disorders? Trends Neurosci. 19:1996;267-271.
45. Ohtsuki T., Matsumoto M., Kitagawa K., Mabuchi T., Mandai K., Matsushita K., Kuwabara K., Tagaya M., Ogawa S., Ueda H., Kamada T., Yanagihara T. Delayed neuronal death in ischemic hippocampus involves stimulation of protein tyrosine phosphorylation. Am. J. Physiol. 271:1996;C1085-C1097.
46. Pringle A.K., Sundstrom L.E., Wilde G.J., Williams L.R., Iannotti F. Brain-derived neurotrophic factor, but not neurotrophin-3, prevents ischaemia-induced neuronal cell death in organotypic rat hippocampal slice cultures. Neurosci. Lett. 211:1996;203-206.
47. Rashid K., van der Zee C.E., Ross G.M., Chapman C.A., Stanisz J., Riopelle R.J., Racine R.J., Fahnestock M. A nerve growth factor peptide retards seizure development and inhibits neuronal sprouting in a rat model of epilepsy. Proc. Natl. Acad. Sci. U.S.A. 92:1995;9495-9499.
48. Rocamora N., Massieu L., Boddeke H.W., Palacios J.M., Mengod G. Differential regulation of the expression of nerve growth factor, brain-derived neurotrophic factor and neurotrophin-3 mRNAs in adult rat brain after intrahippocampal injection of quinolinic acid. Brain Res. Mol. Brain Res. 26:1994;89-98.
49. Shigeno T., Mima T., Takakura K., Graham D.I., Kato G., Hashimoto Y., Furukawa S. Amelioration of delayed neuronal death in the hippocampus by nerve growth factor. J. Neurosci. 11:1991;2914-2919.
50. +] in the hippocampus during recovery from short-term, transient ischemia. J. Cereb. Blood Flow Metab. 12:1992;759-772.
51. Smith M.A., Zhang L.X., Lyons W.E., Mamounas L.A. Anterograde transport of endogenous brain-derived neurotrophic factor in hippocampal mossy fibres. NeuroReport. 8:1997;1829-1834.
52. Smith M.L., Bendek G., Dahlgren N., Rosen I., Wieloch T., Siesjö B.K. Models for studying long-term recovery following forebrain ischemia in the rat: 2. A 2-vessel occlusion model. Acta Neurol. Scand. 69:1984;385-401.
53. Takeda A., Onodera H., Sugimoto A., Kogure K., Obinata M., Shibahara S. Coordinated expression of messenger RNAs for nerve growth factor, brain-derived neurotrophic factor and neurotrophin-3 in the rat hippocampus following transient forebrain ischemia. Neuroscience. 55:1993;23-31.
54. Takeda A., Onodera H., Yamasaki Y., Furukawa K., Kogure K., Obinata M., Shibahara S. Decreased expression of neurotrophin-3 mRNA in the rat hippocampus following transient forebrain ischemia. Brain Res. 569:1992;177-180.
55. Thoenen H. Neurotrophins and neuronal plasticity. Science. 270:1995;593-598.
56. Wessel T.C., Joh T.H., Volpe B.T. In situ hybridization analysis of c-fos and c-jun expression in the rat brain following transient forebrain ischemia. Brain Res. 567:1991;231-240.
57. Whittemore S.R., Friedman P.L., Larhammar D., Persson H., Gonzalez Carvajal M., Holets V.R. Rat beta-nerve growth factor sequence and site of synthesis in the adult hippocampus. J. Neurosci. Res. 20:1988;403-410.
58. 14C ]leucine incorporation into brain proteins in gerbils after transient ischemia: relationship to selective vulnerability of hippocampus J. Neurochem. 56:1991;789-796.
59. T. Wieloch, F. Kamme, Cell signalling and ischemic neuronal death, in: M.D. Ginsberg, J. Bogousslavsky (Eds.), Cerebrovascular Disease, Blackwell, Cambridge (1997) pp. 440-454.
60. Zafra F., Hengerer B., Leibrock J., Thoenen H., Lindholm D. Activity-dependent regulation of BDNF and NGF mRNAs in the rat hippocampus is mediated by non-NMDA glutamate receptors. EMBO J. 9:1990;3545-3550.