Effect of Ni2+ on the testosterone production of mouse primary leydig cell culture

Journal of Toxicology and Environmental Health - Part A

Volumn 55, Issue 3, 1998, Pages 213-224

  Forgács, Zsolt ^a   Paksy, Katalin ^a   Lázár, Péter ^a   Tátrai, Erzsébet ^a  

^a Natl Institute of Chemical Safety   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

CHORIONIC GONADOTROPIN; NICKEL; NICKEL SULFATE; TESTOSTERONE; CALCIUM;

ADRENAL GLAND; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BODY WEIGHT; CELL CULTURE; CELL VIABILITY; CONTROLLED STUDY; DOSE RESPONSE; EPIDIDYMIS; KIDNEY MASS; LEYDIG CELL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TESTIS WEIGHT; TESTOSTERONE SYNTHESIS; ANIMAL; BIOSYNTHESIS; DRUG EFFECT; METABOLISM;

ANIMALS; CALCIUM; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; LEYDIG CELLS; MALE; MICE; NICKEL; TESTOSTERONE;

EID: 0032500376     PISSN: 15287394     EISSN: 10872620     Source Type: Journal    
DOI: 10.1080/009841098158502     Document Type: Article

References (30)

1. Ankel-Fuchs, D., and Thauer, R. K. 1988. Nickel in biology: Nickel as an essential trace element. In The bioinorganic chemistry of nickel, ed. J. R. Lancaster, Jr., pp. 93-110. New York: VHC.
2. Barrett, P. Q., Ertel, E. A., Smith, M. M., Nee, J. J., and Cohen, C. J. 1995. Voltage-gated calcium currents have two opposing effects on the secretion of aldosterone. Am. J. Physiol. 268:C985-992
3. Babich, H., Puerner, J. A., and Borenfreund, E. 1986. In vitro cytotoxicity of metals to bluegill (BF-2) cells. Arch. Environ. Contam. Toxicol. 15:31-37.
4. 1mice exposed for twelve days. Fundam. Appl. Toxicol. 10:164-178.
5. Coogan, T. P., Latta, D. M., Snow, E. T., and Costa, M. 1989. Toxicity and carcinogenicity of nickel compounds. CRC Crit. Rev. Toxicol. 19:341-384.
6. Costa, M. 1991. Molecular mechanisms of nickel carcinogenesis. Annu. Rev. Pharmacol. Toxicol. 31:321-337
7. Deknudt, G. H., and Léonard, A. 1982. Mutagenicity tests with nickel salts in the male mouse. Toxicology 25:289-292.
8. Dierickx, P. J., and Bredael-Rozen, E. 1996. Correlation between the in vitro cytotoxicity of inorganic metal compounds to cultured fathead minnow fish cells and the toxicity to Daphnia magna. Bull. Environ. Contam. Toxicol. 57:107-110.
9. Fletcher, G. G., Rossetto, F. E., Turnbull, J. D., and Nieboer, E. 1994. Toxicity, uptake and mutagenicity of particulate and soluble nickel compounds. Environ. Health Perspect. 102(suppl. 3):69-79.
10. 4 on the ovarian function in rats. Centr. Eur. J. Occup. Environ. Med. 3:48-57.
11. Foulkes, E. C., and Blanck, S. 1984. The selective action of nickel on tubule function in rabbit kidneys. Toxicology 33:245-249.
12. Hall, P. F., Osawa, S., and Mrotek, J. 1981. The influence of calmodulin on steroid synthesis in Leydig cells from rat testis. Endocrinology 109:1677-1682.
13. Hoey, M. J. 1966. The effects of metallic salts on the histology and functioning of the rat testis. J. Reprod. Fertil. 12:461-471.
14. King, M. M., Lynn, K. K., and Huang, C. Y. 1985. Activation of the calmodulin-dependent phosphopro-tein phosphatase by nickel ions. In Progress in nickel toxicology, Proceedings of the International Conference on Nickel Metabolism and Toxicology, eds. S. S. Brown and F. W. Sunderman, J r., 3rd ed., pp. 117-120. Oxford: Blackwell.
15. Laskey, J. W., and Phelps, P. V. 1991. Effect of cadmium and other metal cations on in vitro Leydig cell testosterone production. Toxicol. Appl. Pharmacol. 108:296-306
16. Li, W., Zhao, Y., and Chou, I. N. 1996. Mg + antagonism on Ni +-induced changes in microtubule assembly and cellular thiol homeostasis. Toxicol. Appl. Pharmacol. 136:101-111.
17. 2+-induced cell injury: I. Effects of Ni + on microtubules. Toxicol. Appl. Pharmacol. 106:209-221.
18. Lin, T. 1985. The role of calcium/phospholipid-dependent protein kinase in Leydig cell steroidogenesis. Endocrinology 117:119-126.
19. Mathur, A. K., Datta, K. K., Tandon, S. K., and Dikshith, T. S.S. 1977. Effect of nickel sulphate on male rats. Bull. Environ. Contam. Toxicol. 17:241-248.
20. Maurer, D. R., Wimalasena, J., Indrapichate, K., Puett, D., and Majercik, M. H. 1995. Cytoskeletal regulation of hCG-induced receptor clustering in transformed Leydig cells. Cell. Physiol. Biochem. 5:361-370.
21. Miki, H., Kasprzak, K. S., Kenney, S., and Heine, U. I. 1987. Inhibition of intercellular communication by nickel(II): Antagonistic effect of magnesium. Carcinogenesis 8:1757-1760.
22. Mosmann, T. 1983. Rapid colorimetric assay for cellular growth and survival; Application to proliferation and cytotoxicity assays. J. Immunol. Methods 65:55-63.
23. Ng, T. B., and Liu, W. K. 1990. Toxic effect of heavy metals on cells i solated from the rat adrenal and testis. In Vitro Cell. Dev. Biol. 26:24-28.
24. Oller, A. R., Costa, M., and Oberdorster, G. 1997. Carcinogenicity assessment of selected nickel compounds. Toxicol. Appl. Pharmacol. 143:152-166.
25. Phelps, P. V., and Laskey, J. W. 1989. Comparison of age-related changes in in vivo and in vitro measures of testicular steroidogenesis after acute cadmium exposure in the Sprague-Dawley rat. J. Toxicol. Environ. Health 27:95-105.
26. Raos, N., and Kasprzak, K. S. 1989. Allosteric binding of nickel(II) to calmodulin. Fundam. Appl. Toxicol. 13:816-822.
27. Stocco, D. M., Wells, J., and Clark, B. J. 1993. The effects of hydrogen peroxide on steroidogenesis in mouse Leydig tumor cells. Endocrinology 133:2827-2832.
28. Stoklosowa, S. 1982. Tissue culture of gonadal cells. Acta Biol. Hung. 33:367-379.
29. Waltschewa, W., Slatewa, M., and Michailow, I. 1972. Testicular changes due to long-term administration of nickel sulphate in rats. Exp. Pathol. 6:116-120 (in German).
30. Xie, J., Funakoshi, T., Shimada, FT, and Kojima, S. 1995. Effects of chelating agents on testicular toxicity in mice caused by acute exposure to nickel. Toxicology 103:147-155.