Mg2+ antagonism on Ni2+-induced changes in microtubule assembly and cellular thiol homeostasis

Toxicology and Applied Pharmacology

Volumn 136, Issue 1, 1996, Pages 101-111

  Li, Wande ^a   Zhao, Yinzhi ^a   Chou, Iih Nan ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTATHIONE; MAGNESIUM; METALLOTHIONEIN; NICKEL; THIOL; MAGNESIUM CHLORIDE; NICKEL CHLORIDE; POLYMER; THIOL DERIVATIVE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOSKELETON; CYTOTOXICITY; DRUG ANTAGONISM; MICROTUBULE ASSEMBLY; MOUSE; NONHUMAN; ANIMAL; CELL STRAIN 3T3; CULTURE MEDIUM; CYTOPLASM; CYTOSOL; DRUG EFFECT; FLUORESCENCE MICROSCOPY; HOMEOSTASIS; METABOLISM; MICROTUBULE; PATHOLOGY; PHOTOMETRY; ULTRASTRUCTURE;

3T3 CELLS; ANIMALS; CULTURE MEDIA; CYTOPLASM; CYTOSKELETON; CYTOSOL; GLUTATHIONE; HOMEOSTASIS; MAGNESIUM CHLORIDE; MICE; MICROSCOPY, FLUORESCENCE; MICROTUBULES; NEPHELOMETRY AND TURBIDIMETRY; NICKEL; POLYMERS; SULFHYDRYL COMPOUNDS;

EID: 0029664690     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1006/taap.1996.0012     Document Type: Article

References (49)

1. Abbracchio, M. P., Evens, R. M., Heck, J. D., Cantoni, O., and Costa, M. (1982). The regulation of ionic nickel uptake and cytotoxicity by specific amino acids and serum components. Biol. Trace Elem. Res. 4, 289-301.
2. Alberts, B., Bay, D., Lewis, J., Raff, M., Roberts, K., and Watson, J. D. (Eds.) (1994). Molecular Biology of the Cell, 3nd ed., pp. 787-861. Garland Press, New York.
3. Aune, T. M. (1984). Modification of cellular protein sulfhydryls groups by activated soluble immune response suppressor. J. Immunol. 133, 899-906.
4. Bradford, M. M. (1976). A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254.
5. Buttlaire, D. H., Czuba, B. A., Stevens, T. H., Lee, Y. C., and Himes R. H. (1980). Manganous ion binding to tubulin. J. Biol. Chem. 255, 2164-2168.
6. Chou, I. N. (1989). Distinct cytoskeletal injuries induced by As, Cd, Co, Cr and Ni compounds. Biomed. Environ. Sci. 2, 1-8.
7. Chou, I. N., Li, W., and Zamansky, G. B. (1994). Fluorescence microscopic examination of cytoskeletal elements. In Methods in Toxicology, Vol. 1, Part B, In Vitro Toxicity Indicators (C. A. Tyson and J. M. Frazier, Eds.), pp. 81-95. Academic Press, San Diego.
8. 2+-stimulated increase in acetylated α-tubulin, a marker for stable microtubules (MT), in cultured cells. Toxicologist 15, 308. [Abstract]
9. Christie, N. T., and Costa, M. (1984). In vitro assessment of the toxicity of metal compounds. IV. Disposition of metals in cell: Interactions with membranes, glutathione, metallothionein and DNA. Biol. Trace Elem. Res. 6, 139-158.
10. Conway, K., Wang, X-W., Xu, L-S., and Costa, M. (1987). Effects of magnesium on nickel-induced genotoxicity and cell transformation. Carcinogenesis 8, 1115-1121.
11. Conway, K., Sen, P., and Costa, M. (1986). Antagonistic effect of magnesium chloride on the nickel chloride-induced inhibition of DNA replication in Chinese hamster ovary cells. J. Biochem. Toxicol. 1(1), 11-26.
12. Coogan, T. P., Latta, D. M., Snow, E. T., Costa, M. (1989). Toxicity and carcinogenicity of nickel compounds. CRC Crit. Rev. Toxicol. 19, 341-384.
13. 2+ dependence of guanine nucleotide binding to tubulin. J. Biol. Chem. 262, 17278-17284.
14. Correia, J. J., Beth, A. H., and Williams, R. C., Jr. (1988). Tubulin exchanges divalent cations at both guanine nucleotide-binding sites. J. Biol. Chem. 263, 10681-10686.
15. Costa, M., Nye, J. S., Sunderman, F. W., Jr., Allpass, P. R., and Gondos, B. (1979). Induction of sarcomas in nude mice by implantation of Syrian hamster fetal cells exposed in vitro to nickel subsulfide. Cancer Res. 39, 3591-3597.
16. Costa, M. (1991). Molecular mechanisms of nickel carcinogenesis. Annu. Rev. Pharmacol. Toxicol. 31, 321-327.
17. Eagle, G. R., Zombola, R. R., and Himes, R. H. (1983). Tubulin-zinc interactions: binding and polymerization studies. Biochemistry 22, 221-228.
18. 2+. Biochem. Biophys. Res. Commun. 155, 1464-1470.
19. Grover, S., and Hamel, E. (1994). The magnesium-GTP interaction in microtubule assembly. Eur. J. Biochem. 222, 163-172.
20. Himes, R. H., Lee, Y. C., Eagle, G. R., Haskins, K. M., Babler, S. D., and Ellermeier, J. (1982). The relationship between cobalt binding to tubulin and stimulation of assembly. J. Biol. Chem. 257, 5839-5845.
21. Jemiolo, D. K., and Grisham, C. M. (1982). Divalent cation-nucleotide complex at the exchangeable nucleotide binding site of tubulin. J. Biol. Chem. 257, 8148-8152.
22. Kasprzak, K. S., Quander, R. V., and Poirier, L. A. (1985). Effects of calcium and magnesium salts on nickel subsulfide carcinogenicity in Fischer rats. Carcinogenesis. 6, 1161-1166.
23. Kasprzak, K. S., Waalkes, M. P., and Poirier, L. A. (1986). Antagonism by essential-divalent metals and amino acids of nickel (II)-DNA binding in vitro. Toxicol. Appl. Pharmacol. 82, 336-343.
24. Kuriyama, R., and Sakai, H. (1974). Role of tubulin-SH groups in polymerization to microtubules. J. Biochem. 76, 651-654.
25. Li, W., and Chou, I. N. (1992). Effects of sodium arsenite on the cytoskeleton and cellular glutathione levels in cultured cells. Toxicol. Appl. Pharmacol. 114, 132-139.
26. Li, W., Zhao, Y., and Chou, Y. (1993). Alterations in cytoskeletal protein sulfhydryls and cellular glutathione in cultured cells exposed to cadmium and nickel ions. Toxicology 77, 65-79.
27. 2+ on microtubules. Toxicol. Appl. Pharmacol. 106, 209-221.
28. Lin, K. C. (1993). Effects of Nickel on Microtubule Assembly and the Possible Mechanisms of Nickel-Induced Perturbation in Microtubule Organization. Ph.D. Thesis. Boston University.
29. Littlefield, N. A., Hass, B. S., James, S. J., and Poirier, L. A. (1994). Protective effects of magnesium on DNA strand breaks induced by nickel or cadmium. Cell Biol. Toxicol. 10, 127-135.
30. MacDonald, T. L., Humphreys, W. G., and Martin, R. B. (1987). Promotion of tubulin assembly by aluminum ion in vitro. Science 236, 183-186.
31. Martin, R. B., and Edsall, J. T. (1959). The association of divalent cations with glutathione. J. Am. Chem. Soc. 81, 4044-4047.
32. Meister, A. (1984). New aspects of glutathione biochemistry and transport: Selective alteration of glutathione metabolism. Fed. Proc. 43, 3031-3042.
33. Mejillano, M. R., and Himes, R. H. (1991). Assembly properties of tubulin after carboxyl group modification. J. Biol. Chem. 266, 657-664.
34. Miki, H., Kasprzak, K. S., Kenney, S., and Heine, U. I. (1987). Inhibition of intercellular communication by nickel(II): antagonistic effect of magnesium. Carcinogenesis 8, 1757-1760.
35. Monte, D. D., Ross, D., Bellomo, G., Eklow, L., and Orrenius, L. (1984). Alteration in intracellular thiol homeostasis during the metabolism of menadione by isolated rat hepatocytes. Arch. Biochem. Biophys. 235, 334-342.
36. National Toxicology Program (1994). Seventh Annual Report on Carcinogens. Summary, Public Health Service, U.S. Department of Health and Human Services.
37. Nieboer, E., and Richardson, D. H. S. (1980). The replacement of the nondescript term 'Heavy Metals' by a biologically and chemically significant classification of metal ions. Environ. Pollut., Ser. B. 1, 3-26.
38. Nordberg, G. F., Fowlar, B. A., Friedberg, L., Jernelov, A., Nelson, N. N., Piscator, M., Sandstead, H. H., Vostal, J., and Vouk, V. W. (1978). Factors influencing metabolism and toxicity of metals: A consensus report by the Task Group on Metal Interactions. Environ. Health Perspect. 25, 3-141.
39. O'Brien, E. T., and Erickson, H. P. (1989). Assembly of pure tubulin in the absence of the GTP: Effect of magnesium, glycerol. ATP, and the nonhydrolyzable GTP analogues. Biochemistry 28, 1413-1422.
40. O'Brien, E. T., Salmon, E. D., Walker, R. A., and Erickson, H. P. (1990). Effects of magnesium on the dynamic instability of individual microtubules. Biochemistry 29, 6648-6656.
41. Olmsted, J. B. (1986). Microtubule-associated proteins. Annu. Rev. Cell Biol. 2, 421-457.
42. 2 in magnesium-insoluble regions of fractionated Chinese hamster ovary cell chromatin. Cancer Res. 45, 5787-5794.
43. 2+ on microtubules and tubulin polymerization in vitro. Toxicol. In Vitro 3, 227-234.
44. Sbrana, I., Di Sibio, A., Lomi, A., and Scarcelli, V. (1993). C-mitosis and numerical chromosome aberration analyses in human lymphocytes: 10 known or suspected spindle poisons. Mutat. Res. 287, 57-70.
45. Shaw, J. B., Chou, I. N., and Anand, B. (1988). Rapid phosphorylation of microtubule-associated proteins through distinct mitogenic pathways. J. Biol. Chem. 263, 1459-1466.
46. Sunderman, F. W., Jr. (1986). Carcinogenicity and mutagenicity of some metals and their compounds. In Environmental Carcinogens: Selected Methods of Analysis (I. K. O'Neill, P. Schuller, and L. Fishbein, Eds.), Vol. 8, pp. 17-43. International Agency for Research on Cancer, Lyon, France.
47. Sunderman, F. W., Jr. (1989). Mechanisms of nickel carcinogenesis. Scand. J. Work Environ. Health 15, 1-12.
48. Tietze, F. (1969). Enzymatic method for quantitative determination of nanogram amounts of total and oxidized glutathione. Application to mammalian blood and other tissues. Anal. Chem. 27, 502-522.
49. Zhao, Y., Li, W., and Chou, I. N. (1987). Cytoskeletal perturbation induced by herbicides, 2,4-dichlorophenoxyacetic acid (2,4-D) and 2,4,5-trichlorophenoxyacetic acid (2,4,5-T). J. Toxicol. Environ. Health 20, 11-26.