Angiotensin-converting enzyme inhibitor up-regulates cardiac β- receptors in cultured neonatal rat myocytes

Japanese Circulation Journal

Volumn 61, Issue 2, 1997, Pages 170-179

  Yonemochi, Hidetoshi ^a   Saikawa, Tetsunori ^a   Yasunaga, Seikou ^a   Iwao, Tetsu ^a   Takakura, Takeshi ^a   Nakagawa, Mikiko ^a   Sakata, Toshiie ^a   Ito, Morio ^a  

^a OITA UNIVERSITY   (Japan)

Author keywords

Adrenergic receptor; Angiotensin II; Angiotensin II receptor antagonist; Congestive heart failure; Up regulation

Indexed keywords

4 (3 TERT BUTYLAMINO 2 HYDROXYPROPOXY) 2 BENZIMIDAZOLONE; ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; BETA ADRENERGIC RECEPTOR; CANDESARTAN; CAPTOPRIL; CV 3480; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; HEART RECEPTOR; ISOPRENALINE; RADIOLIGAND; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL CULTURE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG MECHANISM; HEART BEAT; HEART MUSCLE CELL; LIGAND BINDING; MONOLAYER CULTURE; NEWBORN; NONHUMAN; RAT; RECEPTOR DENSITY; RECEPTOR UPREGULATION;

ANGIOTENSIN II; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; ANIMALS, NEWBORN; BENZIMIDAZOLES; CAPTOPRIL; CELLS, CULTURED; MYOCARDIAL CONTRACTION; MYOCARDIUM; RADIOLIGAND ASSAY; RATS; RECEPTORS, ADRENERGIC, BETA; RECEPTORS, ANGIOTENSIN; TETRAZOLES; UP-REGULATION;

EID: 0030938365     PISSN: 00471828     EISSN: None     Source Type: Journal    
DOI: 10.1253/jcj.61.170     Document Type: Article

References (35)

1. Fowler MB, Laser JA , Hopkins GL, Minobe W, Bristow MR: Assessment of the beta-adrenergic receptor pathway in the intact and failing human heart: Progressive receptor down regulation and subsensitivity to agonist response. Circulation 1986; 74: 1290-1302
2. Packer M: Neurohormonal interactions and adaptations in congestive heart failure. Circulation 1988; 77: 721-730
3. Heilbrunn SM, Shah P, Bristow MR, Valantine HA, Ginsburg R, Fowler MB: Increased β-receptor density and improved hemodynamic response to catecholamine stimulation during long-term metoprolol therapy in heart failure from dilated cardiomyopathy. Circulation 1989; 79: 483-490
4. 2-adrenoceptor function. Naunyn-Schmiedeberg's Arch Pharmacol 1990; 342: 429-435
5. Anderson JCL, Lutz JR, Gilbert EM, Sorenson SG, Yanowitz FG, Menlove RL, et al: A randomized trial of low-dose beta blockade therapy for idiopathic dilated cardiomyopathy. Am J Cardiol 1985; 55: 471-475
6. Callucci WS, Alexander RW, Williams GH, Rude RE, Holman BL, Konstam MA, et al: Decreased lymphocyte beta-adrenergic-receptor density in patients with heart failure and tolerance to the beta-adrenergic agonist pirbuterol. N Engl J Med 1981; 305: 185-190
7. Bristow MR, Hershberger RE, Port JD, Gilbert EM, Sandoval A, Rasmussen R, et al: β-adrenergic pathways in nonfailing and failing human ventricular myocardium. Circulation 1990; 82(Suppl I): I-12-I-25
8. Captopril Multicenter Research Group: A placebo-controlled trial of captopril in refractory chronic congestive heart failure. J Am Coll Cardiol 1983; 2: 755-763
9. The CONSENSUS trial study group: Effects of enalapril on mortality in severe congestive heart failure: results of Cooperative North Scandinavian Enalapril Survey Study (CONSENSUS). N Engl J Med 1987; 316: 1429-1435
10. The SOLVD investigators: Effect of enalapril on survival in patients with reduced left ventricular ejection fraction and congestive heart failure. N Engl J Med 1991; 325: 293-302
11. The SOLVD investigators: Effect of enalapril on mortality mid the development of heart failure in asymptomatic patients with reduced left ventricular ejection fraction. N Engl J Med 1992; 327: 685-691
12. Maisel AS, Phillips C, Michel MC, Ziegler MG, Carter SM: Regulations of cardiac β-adrenergic receptors by captopril: Implications for congestive heart failure. Circulation 1989; 80: 669-675
13. Gilbert WM, Sandoval A, Larrabee P, Renlund DG, O'Connell JB, Bristow MR: Lisinopril lowers cardiac adrenergic drive and increases β-receptor density in the failing human heart. Circulation 1993; 88: 472-480
14. Horn EM, Corwin SJ, Steinberg SF, Chow YK, Neuberg GW, Cannon PJ, et al: Reduced lymphocyte stimulatory guanine nucleotide regulatory proteins and β-adrenergic receptors in congestive heart failure and reversal with angiotensin converting enzyme inhibitor therapy. Circulation 1988; 78: 1373-1379
15. Marily W, Ellen OW, Claude RB, Sanford PB, Beverly HL, Hypertrophy trial group: Angiotensin AT1 receptor inhibition: Effects on survival and hypertrophy in aortic bonded rats with persistent pressure overload (abstract). Circulation 1995; 92: I-63
16. Yonemochi H, Saikawa T, Takakura T, Ito S, Takaki R: Effects of calcium antagonist on beta-receptors of cultured myocytes isolated from neonatal rat ventricle. Circulation 1990; 81: 1401-1408
17. Limas CJ, Limas C: Rapid recovery of cardiac beta adrenergic receptors after isoproterenol-induced 'down' regulation. Circ Res 1984; 55: 524-531
18. Staehlin M, Simons P, Jaeggi K, Wigger N: CGP-12177: A hydrophilic beta adrenergic receptor radioligand reveals high affinity binding of agonists to intact cells. J Biol Chem 1983; 258: 3496-3502
19. Kojima M, Shiojima I, Yamasaki K, Komuro I, Zou Yunzeng, Wang Ying, et al: Angiotensin II receptor antagonist TCV-116 induces regression of hypertensive left ventricular hypertrophy in vivo and inhibits the intracellular signaling pathway of stretch-mediated cardiomyocyte hypertrophy in vitro. Circulation 1994; 89: 2204-2211
20. Takakura T, Saikawa T, Yonemochi H, Ito S, Takaki R: Effect of thyroid hormone on the beta -receptor of cardiac myocytes isolated from rat ventricle (in Japanese with English abstract). Folia Endocrinol 1989; 65: 715-727
21. Kenakin T P, Ferris R M: Effects of in vivo β-adrenoceptor down-regulation on cardiac responses to prenalterol and pirbuterol. J Cardiovasc Pharmacol 1983; 5: 90-97
22. Allen IS, Cone NM, Dhallen RS, Gaa ST, Lederer WJ, Rogers TB: Angiotensin II increases spontaneous contractile frequency and stimulates calcium current in cultured neonatal rat heart myocytes: insights into the underlying biochemical mechanisms. Circ Res 1988; 62: 524-534
23. Sadoshima J, Yuhui Xu, Slayter H S, Izumo S: Autocrine release of angiotensin II mediates stretch-induced hypertrophy of cardiac myocytes in vitro. Cell 1993; 75: 977-984
24. Yamazaki T, Komuro I, Kudo S, Yuzeng Zou, Shiojima I, Mizuno T, et al: Angiotensin II partly mediates mechanical stress-induced cardiac hypertrophy. Circ Res 1995; 77: 258-265
25. Roger TB, Gaa ST, Allen IS: Identification and characterization of functional angiotensin II receptors on cultured heart myocytes. J Pharmacol Exp Ther 1986; 236: 438-444
26. Dosemeci A, Dhallan RS, Cohn NM, Lederer WJ, Roger TB: Phorbol ester increases calcium current and simulates the effects of angiotensin II on cultured neonatal rat heart myocytes. Circ Res 1988; 62: 347-357
27. Yoshimasa T, Sibley DR, Bouvier M, Lefkowitz RJ, Caron MG: Cross talk between cellular signaling pathways suggested by phorbol-ester-induced adenylyl cyclase phosphorylation. Nature 1987; 327: 67-70
28. Wallukat G, Mowinski R, Kuhn H: Modulation of the β-adrenergic response of cardiomyocytes by specific lipoxygenase products involves their incorporation into phosphatidylinositol and activation of protein kinase C. J Biol Chem 1994; 269: 23032-23038
29. Yuan N, Friedman J, Whaley BS, Clark RB: cAMP-dependent kinase and protein kinase C consensus site mutation of the β-adrenergic receptor. J Biol Chem 1994; 269: 23032-23038
30. Feolde E, Vinge P, Frelin C: Angiotensin II receptor subtypes and biological responses in the rat heart. J Mol Cell Cardiol 1993; 25: 1359-1367
31. Gohlke P, Linz W, Sholkens BA, Kuwer I, Bartenbach S, Schnell A, et al: Angiotensin-converting enzyme inhibitor improves cardiac function: Role of bradykinin. Hypertension 1994; 23: 411-418
32. Trippodo NC, Panchal BC, Fox M: Repression of angiotensin II and potentiation of bradykinin contribute to the synergistic effects of dual metalloprotease inhibition in heart failure. J Pharmacol Exp Ther 1995; 272: 619-627
33. Saruta T, Nishikawa K: Characteristics of a new angiotensin converting enzyme inhibitor: delapril. Am J Hypertens 1991; 4: 23s-28s
34. Okunisi H, Oka Y, Shiota N, Kawamoto T, Song K, Miyazaki M: Marked species-difference in the vascular angiotensin II-forming pathway: Human vs rodents. Jpn J Pharmacol 1993; 62: 207-210
35. Urata H, Healy B, Stewart R W, Bumpus M, Husain A: Angiotensin II-forming pathways in normal and failing human hearts. Circ Res 1990; 66: 883-890