Epidoxoform: A hydrolytically more stable anthracycline-formaldehyde conjugate toxic to resistant tumor cells

Journal of Medicinal Chemistry

Volumn 41, Issue 8, 1998, Pages 1306-1314

  Taatjes, Dylan J ^c   Fenick, David J ^b   Koch, Tad H ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

DAUNOFORM; DAUNORUBICIN DERIVATIVE; DOXOFORM; DOXORUBICIN DERIVATIVE; EPIDOXOFORM; EPIRUBICIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL STRAIN MCF 7; DRUG CONFORMATION; DRUG DNA BINDING; DRUG HALF LIFE; DRUG HYDROLYSIS; DRUG POTENCY; DRUG STABILITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; STRUCTURE ACTIVITY RELATION;

ANTIBIOTICS, ANTINEOPLASTIC; CELL DIVISION; DNA ADDUCTS; DOXORUBICIN; DRUG RESISTANCE, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; EPIRUBICIN; HUMANS; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; OLIGONUCLEOTIDES; TUMOR CELLS, CULTURED;

EID: 0032499267     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm970739s     Document Type: Article

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