Production of formaldehyde and DNA-adriamycin or DNA-daunomycin adducts, initiated through redox chemistry of dithiothreitol/iron, xanthine oxidase/NADH/iron, or glutathione/iron

Chemical Research in Toxicology

Volumn 10, Issue 9, 1997, Pages 953-961

  Taatjes, Dylan J ^a   Gaudiano, Giorgio ^a,b   Koch, Tad H ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b CNR   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRACYCLINE; DAUNORUBICIN; DEFEROXAMINE MESYLATE; DITHIOTHREITOL; DNA; DOXORUBICIN; EDETIC ACID; FERRIC CHLORIDE; FERRIC ION; FORMALDEHYDE; GLUTATHIONE; HYDROGEN PEROXIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; SPERMINE; XANTHINE OXIDASE;

ARTICLE; CARCINOMA CELL; CHEMICAL BOND; CONTROLLED STUDY; CYTOTOXICITY; DNA ADDUCT; HUMAN; HUMAN CELL; OXIDATION REDUCTION REACTION;

ANAEROBIOSIS; ANTIBIOTICS, ANTINEOPLASTIC; BUFFERS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DAUNORUBICIN; DITHIOTHREITOL; DNA ADDUCTS; DOXORUBICIN; FORMALDEHYDE; GLUTATHIONE; HYDROGEN PEROXIDE; INDICATORS AND REAGENTS; IRON; NAD; OXIDATION-REDUCTION; XANTHINE OXIDASE;

EID: 0030850590     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx970064w     Document Type: Article

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