Lack of association between schizophrenia and HLA DQB1 alleles in a Swedish sample

Schizophrenia Research

Volumn 29, Issue 3, 1998, Pages 293-296

  Jönsson, Erik G ^a   Zhang, Feng ^b   Nimgaonkar, Vishwajit L ^b   Rudert, William A ^b   Sedvall, Göran C ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

Association study; Genetics; HLA; HLA DQB1; Schizophrenia

Indexed keywords

HLA DQ ANTIGEN; LEUKOCYTE ANTIGEN;

ADULT; AGED; ALLELE; ARTICLE; CAUCASIAN; CONTROLLED STUDY; FEMALE; GENETIC ASSOCIATION; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SCHIZOPHRENIA; SWEDEN;

ADULT; AGED; AGED, 80 AND OVER; ALLELES; FEMALE; GENE FREQUENCY; HLA-DQ ANTIGENS; HUMANS; MALE; MIDDLE AGED; RISK FACTORS; SCHIZOPHRENIA; SCHIZOPHRENIC PSYCHOLOGY; SWEDEN;

EID: 0032498518     PISSN: 09209964     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0920-9964(97)00104-7     Document Type: Article

References (16)

1. American Psychiatric Association, 1987. Diagnostic and Statistical Manual of Mental Disorders, 3rd edn - revised. American Psychiatric Association, Washington DC, 567 pp.
2. Chakraborty, R., Kamboh, M.I., Nwankwo, M., Ferrell, R.E., 1992, Caucasian genes in American blacks: new data. Am. J. Hum. Genet. 50, 145-155.
3. Cloninger, C.R., 1997. Multilocus genetics of schizophrenia. Curr. Opin. Psychiatry 10, 5-10.
4. Erdfelder, E., Faul, F., Buchner, A., 1996. GPower: a general power analysis program. Behav. Res. Methods Instruments Comput. 28, 1-11.
5. Ganguli, R., Brar, J.S., Chengappa, K.N.R., Yang, Z.W., Nimgaonkar, V.L., Rabin, B.S., 1993. Autoimmunity in schizophrenia: a review of recent findings. Ann. Med. 25, 489-496.
6. Geijer, T., Neiman, J., Rydberg, U., Gyllander, A., Jönsson, E., Sedvall, G., Valverius, P., Terenius, L., 1994. Dopamine D2 receptor gene polymorphisms in Scandinavian chronic alcoholics. Eur. Arch. Psychiatry Clin. Neurosci. 244, 26-32.
7. Jönsson, E., Lannfelt, L., Sokoloff, P., Schwartz. J.-C., Sedvall, G., 1993. Lack of association between schizophrenia and alleles in the dopamine D3 receptor gene. Acta Psychiatr. Scand. 87, 345-349.
8. Kendler, K.S., Diehl, S.R., 1993. The genetics of schizophrenia: a current, genetic-epidemiologic perspective. Schizophr. Bull. 19, 261-285.
9. Maruya, E., Saji, H., Yokoyama, S., 1996. PCR-LIS-SSCP (Low Ionic Strength Single-Stranded Conformation Polymorphism) - a simple method for high-resolution allele typing of HLA-DRB1, -DQB1, and -DPB1. Genome Res. 6, 51-57.
10. Nimgaonkar, V.L., Ganguli, R., Rudert, W.A., Vavassori, C., Rabin, B.S., Trucco, M., 1992. A negative association of schizophrenia with an allele of the HLA DQB1 gene among African-Americans. Schizophr. Res. 8. 199-209.
11. Nimgaonkar, V.L., Rudert, W.A., Zhang, X.R., Tsoi, W.-F., Trucco, M., Saha, N., 1995. Further evidence for an association between schizophrenia and the HLA DQB1 gene locus. Schizophr. Res. 18, 43-49.
12. Nimgaonkar, V.L., Rudert, M.A., Zhang, X.R., Trucco, M., Ganguli, R., 1997. Negative association of schizophrenia with HLA DQB1*0602: supportive evidence from a second African-American cohort. Schizophr. Res. 23, 81-86.
13. Olerup, O., Aldener, A., Fogdell, A., 1993. HLA-DQB1 and -DQA1 typing by PCR amplification with sequence specific primers (PCR-SSP) in 2 hours. Tissue Antigens 41, 119-134.
14. Sham, P.C., Curtis, D., 1995. Monte Carlo tests for associations between disease and alleles at highly polymorphic loci. Ann. Hum. Genet. 59, 97-105.
15. Wright, P., Donaldson, P.T., Underbill, J.A., Choudhuri, K., Doherty, D.G., Murray, R.M., 1996. Genetic association of the HLA DRB1 gene locus on chromosome 6p21.3 with schizophrenia. Am. J. Psychiatry 153, 1530-1533.
16. Zamani, M.G., De Hert, M., Spaepen, M., Hermans, M., Marynen, P., Cassiman, J.-J., Peuskens, J., 1995. Study of the possible association of HLA class II, CD4, and CD3 polymorphisms with schizophrenia. Am. J. Med. Genet. 54, 372-377.