A proposal for a new direction to treat cancer

Journal of Theoretical Biology

Volumn 195, Issue 1, 1998, Pages 111-128

  Rose, Sam ^a  

^a Aduro BioTech Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; RADIOACTIVE IODINE;

ARTICLE; DISSEMINATED CANCER; DRUG ACCUMULATION; DRUG TARGETING; PRIORITY JOURNAL; THYROID CANCER;

EID: 0032494691     PISSN: 00225193     EISSN: None     Source Type: Journal    
DOI: 10.1006/jtbi.1998.0792     Document Type: Article

References (59)

1. ADELSTEIN, S. J. & KASSIS, A. L. (1987). Radiobiologic implications of the microscopic distribution of energy from radionuclides. Int. J. Rad. Appl. Instrum. (B) 14, 165-169.
2. BAILLIE, C. T., WINSLET, M. C. & BRADLEY, N. J. (1995). Tumor vasculature - a potential therapeutic target. Br. J. Cancer 72, 257-267.
3. VAN BASTEN, J. P., SCHRAFFORD KOOPS, H., SLEIJFER, D. T., PRAS, E., VAN DRIEL, M. F. & HOEKSTRA, H. J. (1997). Current concepts about testicular cancer. Eur. J. Surg. Oncol. 23, 354-360.
4. BOGDANFFY, M. S., DREEF-VAN DER MEULEN, H. C., BEEMS, R. B., FERON, V. J., CASCIERI, T. C., TYLER, T. R., VINEGAR, M. B. & RICKARD, R. W. (1994). Chronic toxicity and oncogenicity inhalation study with vinyl acetate in the rat and mouse. Fundam. Appl. Toxicol. 23, 215-229.
5. 131I-labeled TNT-1 monoclonal antibody. Cancer Res. 49, 4578-4585.
6. CHEN, F. M., EPSTEIN, A. L., LI, Z. & TAYLOR, C. R. (1990). A comparative autoradiographic study demonstrating differential intra-tumor localization of monoclonal antibodies to cell surface (Lym-1) and intracellular (TNT-1) antigens. J. Nucl. Med. 31, 1059-1066.
7. CHENG, K. C. & LOEB, L. A. (1993). Genomic instability and tumor progression: mechanistic considerations. Adv. Cancer Res. 60, 121-156.
8. CORDON-CARDO, C., FUKS, Z., DROBNJAK, M., MORENO, C., EISENBACH, L. & FELDMAN, M. (1991). Expression of HLA-A,B,C antigens on primary and metastatic tumor cell populations of human carcinomas. Cancer Res. 51, 6372-6380.
9. COULIE, P. G., BRICHARD, V., VAN PEL, A., WOLFEL, T., SCHNEIDER, C., TRAVERSARI, E., DE PLAEN, E., LURQUIN, C., SZIKORA, J. P., RENAULD, J. C. & BOON, T. (1994). A new gene coding for a differentiation antigen recognized by autologous cytologic T lymphocytes on HLA-A2 melanomas. J. Exp. Med. 180, 35-42.
10. CROITORU, K. & RIDDELL, R. H. (1993). Reduce, reuse, and recycle: shedding light on shedding cells. Gastroenterology 105, 1089-1097.
11. ELLIOTT, B. E., CARLOW, D. A., RODRICKS, A. M. & WADE, A. (1989). Perspectives on the role of MHC antigens in normal and malignant cell development. Adv. Cancer Res. 52, 181-245.
12. FALLOWFIELD, M. E. & COOK, M. G. (1990). Lymphatics in primary cutaneous melanoma. Am. J. Surg. Pathol. 14, 370-374.
13. FINOTTO, S. RADO, V., DAL VECCHIO, A., MILANI, G., FABBRI, L. M. & MAESTRELLI, P. (1993). Identification of epithelial cells in bronchoalveolar lavage. Hum. Exp. Toxicol. 12, 43-46.
14. FIRESTONE, R. A. (1994). Low density lipoprotein as a vehicle for targeting antitumor compounds to cancer cells. Bioconjugate 5, 105-113.
15. FITZGERALD, P. F., FOOTE, F. W. & HILL, R. F. (1950). Concentration of I131 in thyroid cancer shown by radioautography. Cancer 3, 86-105.
16. FOULDS, L. (1969). Neoplastic Development I. New York: Academic Press.
17. FOULDS, L. (1975). Neoplastic Development II. New York: Academic Press.
18. FUJITA, S., PURI, R., Yu, Z. X., TRAVIS, W., YAMAGUCHI, M. & FERRANS, V. J. (1994). Interleukin-1 alpha reduces the severity of the vascular leak syndrome produced by interleukin-2 and interleukin-2 plus interferon alpha. Toxicol. Pathol. 22, 381-397.
19. GEUZE, H. J., VAN DER DONK, H. A., SIMMONS, C. F., SLOT, J. W., STROUS, G. J. & SCHWARTZ, A. L. (1986). Receptor-mediated endocytosis in liver parenchymal cells. Inter. Rev. Exp. Path. 29, 113-171.
20. GOLIGORSKY, M. S., LIEBERTHAL, W., RACUSEN, L. & SIMON, E. E. (1993). Integrin receptors in renal tubular epithelium: new insights into pathophysiology of acute renal failure. Am. J. Physiol. 264, 1-8.
21. GOPAS, J., RAGER-ZISMAN, B., BAR-ELI, M., HAMMERLING, G. & SEGAL, S. (1989). The relationship between MHC antigen expression and metastasis. Adv. Cancer Res. 53, 89-115.
22. HILL, R. P. (1990). Tumor progression: potential role of unstable genomic changes. Cancer Metastasis Rev. 9, 137-147.
23. HOUGHTON, A. N. (1994). Cancer antigens: immune recognition of self and altered self. J. Exp. Med. 180, 1-4.
24. IKOMI, F., HANNA, G. K. & SCHMID-SCHONBEIN, G. W. (1995). Mechanism of colloidal uptake into the lymphatic system: base study with percutaneous lymphography. Radiology 196, 107-113.
25. ISHIKAWA, T., TARNAWSKI, A., SARFEH, I. J. & STACHURA, J. (1993). Epidermal growth factor protects gastric mucosa against ischemia-reperfusion injury. J. Clin. Gastroenterol. 17(Suppl. 1), 104-110.
26. JAIN, R. K. (1987). Transport of molecules in the tumor interstitium: a review. Cancer Res. 47, 3039-3051.
27. JANSEN, R. W., KRUIJT, J. K., VAN BERKEL, T. J. C. & MEIJER, D. K. (1993). Coupling of the antiviral drug Ara-AMP to lactosminated albumin leads to specific uptake in rat and human hepatocytes. Hepatology 18, 146-152.
28. KAWAKAMI, Y., ELIYANU, S., DELGADO, C. H., ROBBINES, P. F., RIVOLTINI, S. L., TOPALIAN, S. L., MIKI, T. & ROSENBERG, S. A. (1994). Cloning of the gene coding for a shared human melanoma antigen recognized by autologous T cells infiltrating into tumor. Proc. Nat. Acad. Sci. U.S.A. 91, 3515-3519.
29. KHAW, B. A., MATTIS, J. A., MELINCOFF, G., STRAUSS, H. W., GOLD, H. K. & HABER, E. (1984). Monoclonal antibody to cardiac myosin imaging of experimental myocardial infraction. Hybridoma 3, 11-23.
30. KLEIN, G. (1998). Foulds' dangerous idea revisited: the multistep development of tumors 40 years later. Adv. Cancer Res. 72, 1-23.
31. LOEB, L. (1998). Cancer cells exhibit a mutator phenotype. Adv. Cancer Res. 72, 25-56.
32. MATSUMURA, Y. & MAEDA, H. (1986). A new concept for macromolecular therapeutics in cancer therapy: mechanism of tumor accumulation of proteins and antitumor agent SMANCS. Cancer Res. 46, 6387-6392.
33. MURPHY, R. F. (1988). Processing of endocytosed material. Adv. Cell Biol. 2, 159-180.
34. VAN NOESEL, N. M., HAHLEN, K., HAKVOORT-CAMMEL, F. G. & EGELER, R. M. (1997). Neuroblastoma 4s: a heterogeneous disease with variable risk factors and treatment strategies. Cancer 80, 834-843.
35. O'BRIEN & BOLTON (1995).
36. PASTAN, I. (1997). Targeted therapy of cancer with recombinant immunotoxins. Biochem. Biophys. Acta (Netherlands) 1333, c1-6.
37. PEARSE, B. M. F. & BRETSCHER, M. S. (1981). Membrane recycling by coated vesicles. Ann. Rev. Biochem. 50, 85-101.
38. PITTMAN, R. C. & STEINBERG, D. (1978). A new approach for assessing cumulative lysosomal degradation of proteins or other macromolecules. Biochem. Biophys. Res. Com. 81, 1254-1259.
39. PITTMAN, R. C., ATTIE, A. D., CAREW, T. E. & STEINBERG, D. (1979a). Tissue sites of degredation of low density lipoprotein: application of a method for determining the fate of plasma proteins. Proc. Nat. Acad. Sci. U.S.A. 76, 5345-5349.
40. PITTMAN, R. C., GREEN, S. R., ATTIE, A. D. & STEINBERG, D. (1979b). Radiolabeled sucrose covalently linked to protein. J. Biol. Chem. 254, 6876-6879.
41. PITTMAN, R. C., CAREW, T. E., GLASS, C. K., GREEN, S. R., TAYLOR, C. A. & ATTIE, A. D. (1983). A radioiodinated, intracellularly trapped ligand for determining the sites of plasma protein degredation in vivo. Biochem. J. 212, 719-800.
42. PREHN, R. T. (1994). Cancers beget mutations versus mutations begat cancers. Cancer Res. 54, 5296-5230.
43. REBEL, J. M., THIJSSEN, C. D., VERMEY, M., DELOUVEE, A., ZWARTHOFF, E. C. & VAN DER KWAST, T. H. (1994). E-cadherin expression determines the mode of replacement of normal urothelium by human bladder carcinoma cells. Cancer Res. 54, 5488-5492.
44. RODRIGUES, M. L., PRESTA, L. G., KOTTS, C. E., WIRTH, C., MORDENTI, J., OSAKA, G., WONG, W. L., NUIJENS, A., BLACKBURN, B. & CARTER, P. (1995). Development of a humanized disulfide-stabilized anti-p185HER2 Fv-beta-lactamase fusion protein for activation of a cephalosporin doxorubicin prodrug. Cancer Res. 55, 63-70.
45. RUBIN, H. (1990). The significance of biological heterogeneity. Cancer Metastasis Rev. 9, 1-20.
46. RUSHFELDT, C. & SMEDSROD, B. (1993). Distribution of colon cancer cells permanently labeled by lecitin-mediated endocytosis of a trap label. Cancer Res. 53, 658-662.
47. SCHEINBERG, D. A. (1995). Adult leukemia in 1995: new directions. Lancet 346(8973), 455-456.
48. SEYMOUR, L. W. (1992). Passive tumor targeting of soluble macromolecules and drug conjugates. Crit. Rev. Therapeutic Drug Carrier Systems 9, 135-187.
49. SMITH, G. K., BANKS, S., BLUMENKOPF T. A., CORY, M., HUMPHREYS, J., LAETHEM, R. M., MILLER, J., MOXHAM, C. P., MULLIN, R., RAY, P. H., WALTON, L. M. & WOLFE, L. A. 3rd. (1997). Toward antibody-directed enzyme prodrug therapy with the T268G mutant of human carboxypeptidase A1 and novel in vivo stable prodrugs of methotrexate. J. Biol. Chem. 272, 15804-15816.
50. SOLER-RODRIGUEZ, A. M., GHETIE, M. A., OPPENHEIMER-MARKS, N., UHR, J. W. & VITETTA, E. S. (1993). Ricin A chains and ricin A chain immunotoxins rapidly damage human endothelial cells, implications for vascular leak syndrome. Exp. Cell Res. 206, 227-234.
51. STEWART, B. W. (1994). Mechanisms of apoptosis: integration of genetic, biochemical, and cellular indicators. J. Nat. Cancer Inst. 86, 1286-1296.
52. TRINH, Q. T., AUSTIN, E. A., MURRAY, D. M., KNICK, V. C. & HUBER, B. E. (1995). Enzyme/prodrug gene therapy: comparison of cytosine deaminase/5-flurocytosine versus thymidine kinase/ganciclovir enzyme/prodrug systems in a human colorectal carcinoma cell line. Cancer Res. 55, 4808-4812.
53. WALKER, P. D. (1994). Alterations in renal tubular extracellular matrix components after ischemia reperfusion injury to the kidney. Lab. Invest. 70, 339-345.
54. WEISS, U. & RAJEWSKY, K. (1990). The repertoire of somatic antibody mutants accumulating in the memory compartment after primary immunization is restricted through affinity maturation and mirrors that expressed in the secondary response. J. Exp. Med. 172, 1681-1689.
55. WU, G. Y., WU, C. H. & STOCKERT, R. J. (1983). Model for specific rescue of normal hepatocytes during methotrexate treatment for hepatic malignancy. Proc. Nat. Acad. Sci. U.S.A. 80, 3078-3080.
56. WU, G. Y., WU, C. H. & RUBIN, M. I. (1985). Acetaminophen hepatotoxicity and targeted eescue: a model for specific chemotherapy of hepatocellular carcinoma. Hepatology 5, 709-713.
57. WYLLIE, A. H. (1992). Apoptosis and the regulation of cell numbers in normal and neoplastic tissues: an overview. Cancer Metastasis Rev. 11, 95-103.
58. YONG, L. C. J. & RHODES (1990). The clearance of heterologous antibodies in experimental antibasement membrane antibody mediated glomerulonephritis. Exp. Pathol. 39, 79-87.
59. YUZAWA, Y., BRENTJENS, J. R., BRETT, J., CALDWELL, P. R., ESPOSITIO, C., FUKASTU, A., GODMAN, G., STERN, D. & ANDRES, G. (1994). Antibody-mediated redistribution and shedding of endothelial antigens in the rabbit. J. Immunol. 150, 5633-5646.