Solution structure of the B-Myb DNA-binding domain: A possible role for conformational instability of the protein in DNA binding and control of gene expression

Biochemistry

Volumn 37, Issue 27, 1998, Pages 9619-9629

  McIntosh, Pauline B ^b   Frenkiel, Tom A ^c   Wollborn, Ute ^c   McCormick, John E ^c   Klempnauer, Karl Heinz ^d   Feeney, James ^c   Carr, Mark D ^a,b  

^a UNIVERSITY OF KENT   (United Kingdom)

^b NATIONAL INSTITUTE FOR BIOLOGICAL STANDARDS AND CONTROL   (United Kingdom)

^c NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^d MAX PLANCK INSTITUTE OF IMMUNOBIOLOGY AND EPIGENETICS   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DNA BINDING PROTEIN; MYC PROTEIN; ONCOPROTEIN;

ARTICLE; GENE EXPRESSION REGULATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; ONCOGENE C MYB; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DNA BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PURIFICATION; PROTEIN STABILITY; PROTEIN TERTIARY STRUCTURE;

ANIMALS; BINDING SITES; CELL CYCLE PROTEINS; CRYSTALLOGRAPHY, X-RAY; DNA; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; MACROMOLECULAR SUBSTANCES; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; ONCOGENES; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-MYB; SEQUENCE HOMOLOGY, AMINO ACID; SOLUTIONS; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS;

EID: 0032493479     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi972861z     Document Type: Article

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