Ability of single-site mutants of citrate synthase to catalyze proton transfer from the methyl group of dethiaacetyl-coenzyme A, a non-thioester substrate analog

Biochemistry

Volumn 36, Issue 13, 1997, Pages 3981-3990

  Kurz, Linda C ^a   Roble, James H ^a   Nakra, Tanuj ^a   Drysdale, George R ^a   Buzan, Jenny M ^a   Schwartz, Benjamin ^b   Drueckhammer, Dale G ^b  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CITRATE SYNTHASE; COENZYME A; MUTANT PROTEIN;

ANIMAL TISSUE; ARTICLE; CIRCULAR DICHROISM; DNA SEQUENCE; ENZYME KINETICS; ENZYME MECHANISM; EXPRESSION VECTOR; HEART; MOLECULAR CLONING; MUTAGENESIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTON TRANSPORT; SWINE;

ACETYL COENZYME A; ANIMALS; BINDING SITES; CIRCULAR DICHROISM; CITRATE (SI)-SYNTHASE; CLONING, MOLECULAR; DNA PRIMERS; ESCHERICHIA COLI; GENE EXPRESSION; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; MUTATION; MYOCARDIUM; OXALOACETATES; OXALOACETIC ACIDS; PROTONS; SWINE;

EID: 0030946488     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi963058s     Document Type: Article

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