Acute morphine dependence in mice selectively-bred for high and low analgesia

Neuroscience Letters

Volumn 256, Issue 2, 1998, Pages 120-122

  Kest, Benjamin ^a   McLemore, Gabrielle L ^b   Sadowski, Bogdan ^c   Mogil, Jeffrey S ^d   Belknap, John K ^e   Inturrisi, Charles E ^b  

^a CITY UNIVERSITY OF NEW YORK   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c INSTITUTE OF GENETICS AND ANIMAL BREEDING   (Poland)

^d UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^e OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Antinociception; Naloxone; Opioid; Selective breeding; Withdrawal

Indexed keywords

MORPHINE; NALOXONE; NARCOTIC ANALGESIC AGENT; NARCOTIC ANTAGONIST;

ANALGESIA; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANTINOCICEPTION; ARTICLE; BREEDING; CONTROLLED STUDY; DRUG DEPENDENCE; DRUG SENSITIVITY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; STRESS; SUBCUTANEOUS DRUG ADMINISTRATION; WITHDRAWAL SYNDROME;

ANALGESIA; ANIMALS; BEHAVIOR, ANIMAL; DISEASE MODELS, ANIMAL; EXERCISE TEST; LEVORPHANOL; MALE; MICE; MICE, INBRED STRAINS; MORPHINE; MORPHINE DEPENDENCE; NALOXONE; SELECTION (GENETICS);

EID: 0032491510     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(98)00772-1     Document Type: Article

References (10)

1. Belknap J.K., Danielson P.W., Laursen S.E., Noordewier B. Selective breeding for levorphanol-induced antinociception on the hot-plate assay: commonalities in mechanism of action with morphine, pentazocine, ethylketocyclazocine, U-50488H and clonidine in mice. J. Pharmacol. Exp. Ther. 241:1987;477-481.
2. Belknap J.K., Haltli N.R., Goebel D.M., Lamé M. Selective breeding for high and low levels of opiate-induced analgesia in mice. Behav. Genet. 13:1983;383-396.
3. Belknap, J.K., O'Toole, L.A., Studies of genetic differences in response to opioid drugs. In J.C. Crabbe and R.A. Harris (Eds.), The Genetic Basis of Alcohol and Drug Actions, Plenum Press, NY, 1991, pp. 225-252.
4. Crabbe J.C., Phillips T.J., Kosobud A., Belknap J.K. Estimation of genetic correlation: interpretation of experiments using selectively bred and inbred animals. Alcohol.: Clin. Exp. Res. 14:1990;141-151.
5. Kest B., Lee C.E., McLemore G.L., Inturrisi C.E. An antisense oligodeoxynucleotide for the delta opioid receptor (DOR-1) inhibits morphine tolerance and acute dependence. Brain Res. Bull. 39:1996;185-188.
6. Marek P., Mogil J.S., Belknap J.K., Sadowski B., Liebeskind J.C. Levorphanol and swim stress-induced analgesia in selectively bred mice: evidence for genetic commonalities. Brain Res. 608:1993;353-357.
7. Marshall I., Weinstock M. A quantitative method for the assessment of physical dependence on narcotic analgesics in mice. Br. J. Pharmacol. 37:1969;505P-506P.
8. Mogil J.S., Flodman P., Spence M.A., Sternberg W.F., Kest B., Sadowski B., Liebeskind J.C., Belknap J.K. Oligogenic determination of morphine analgesic magnitude: a genetic analysis of selectively bred mouse lines. Behav. Genet. 25:1995;397-406.
9. Mogil, J.S., Kest, B., Sadowski, B. and Belknap, J.K., Differential genetic mediation of sensitivity to morphine in genetic models of opiate analgesia: influence of nociceptive assay, J. Pharmacol. Exp. Ther., 276: 532-544.
10. Panocka I., Marek P., Sadowski B. Inheritance of stress-induced analgesia in mice. Selective breeding study. Brain Res. 397:1986;152-155.