Nonsteroidal progesterone receptor antagonists based on a conformationally-restricted subseries of 6-aryl-1,2-dihydro-2,2,4- trimethylquinolines

Bioorganic and Medicinal Chemistry Letters

Volumn 8, Issue 19, 1998, Pages 2731-2736

  Hamann, Lawrence G ^a   Winn, David T ^a,b   Pooley, Charlotte L F ^a   Tegley, Christopher M ^a   West, Sarah J ^a   Farmer, Luc J ^a,c   Zhi, Lin ^a   Edwards, James P ^a   Marschke, Keith B ^a   Mais, Dale E ^a   Goldman, Mark E ^a,d   Jones, Todd K ^a,e  

^a LIGAND PHARMACEUTICALS INC   (United States)

^b PFIZER INC   (United States)

^c VERTEX PHARMACEUTICALS   (United States)

^d Axiom Biotechnologies Inc   (United States)

^e Ontogen Corporation   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGESTAGEN; DRUG CARRIER; MIFEPRISTONE; QUINOLINE DERIVATIVE;

ACYLATION; ANIMAL CELL; ARTICLE; DRUG CONFORMATION; DRUG EFFICACY; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; MAMMAL CELL; NONHUMAN; REACTION ANALYSIS; REPORTER GENE;

HUMANS; MOLECULAR CONFORMATION; QUINOLINES; RECEPTORS, PROGESTERONE; STRUCTURE-ACTIVITY RELATIONSHIP;

ANIMALIA; MAMMALIA;

EID: 0032491268     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(98)00482-X     Document Type: Article

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