Complestatin and chloropeptin I, condensed aromatic peptides from two strains of streptomycetes

Tetrahedron Letters

Volumn 39, Issue 32, 1998, Pages 5683-5684

  Hegde, Vinod R ^a   Dai, Ping ^a   Patel, Mahesh ^a   Gullo, Vincent P ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CHLOROPEPTIN I; COMPLESTATIN; GLYCOPROTEIN GP 120; PEPTIDE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG ISOLATION; DRUG STRUCTURE; DRUG SYNTHESIS; FERMENTATION; FIBRINOLYSIS; STREPTOMYCETACEAE;

EID: 0032490905     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(98)01145-9     Document Type: Article

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11. 6. Both were fermented using the same fermentation medium under identical fermentation conditions for 120 hours. The pH during the fermentation ranged from 5.5 to 6.5 for both strains.
12. 3CN : 0.025% TFA (45:55), 1 ml/min, Rt 14.1 min. for 1 and Rt 20.05 min. for 2.
13. 3CN for 25 min. 1 ml/min, Rt 28.4 min. for 1 and 31.8 min. for 2.