Neural disease: Drosophila degenerates for a good cause

Current Biology

Volumn 8, Issue 22, 1998, Pages

  Mutsuddi, Mousumi ^a   Nambu, John R ^a  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA;

EID: 0032488044     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0960-9822(07)00506-4     Document Type: Article

References (21)

1. Roses AD: From genes to mechanisms to therapies: lessons to be learned from neurological disorders. Nat Med 1996, 2:267-269.
2. Davidson FF, Steller H: Blocking apoptosis prevents blindness in Drosophila retinal degeneration mutants. Nature 1998, 391:587-591.
3. Griffiths IR: Myelin mutants: model systems for the study of normal and abnormal myelination. BioEssays 18:789-797.
4. Buchanan RL, Benzer S: Defective glia in the Drosophila brain degeneration mutant drop-dead. Neuron 1993, 10:839-850.
5. Kretzschmar D, Hasan G, Sharma S, Heisenberg M, Benzer S: The swiss cheese mutant causes glial hyperwrapping and brain degeneration in Drosophila. J Neurosci 1997, 17:7425-7432.
6. Rogina B, Benzer S, Helfand SL: Drosophila drop-dead mutations accelerate the time course of age-related markers. Proc Natl Acad Sci USA 1997, 94:6303-6306.
7. Lush MJ, Li Y, Read DJ, Willis AC, Glynn P: Neuropathy target esterase and a homologous Drosophila neurodegeneration-associated mutant protein contain a novel domain conserved from bacteria to man. Biochem J 1998, 332:1-4.
8. Min K-T, Benzer S: Spongecake and eggroll: two hereditary disease in Drosophila resemble patterns of human brain degeneration. Curr Biol 1997, 7:885-888.
9. Eberl DF, Duyk GM, Perrimon N: A genetic screen for mutations that disrupt an auditory response in Drosophila melanogaster. Proc Natl Acad Sci USA 1997, 94:14837-14842.
10. Bracha HS, Shults C, Glick SD, Kleinman JE: Spontaneous asymmetric circling behavior in hemi-parkinsonism; a human equivalent of the lesioned-circling rodent behavior. Life Sci 1987, 40:1127-1130.
11. Luo L, Tully T, White K: Human amyloid precursor protein ameliorates behavioral deficit of flies deleted for Appl gene. Neuron 1992, 9:595-605.
12. Phillips JP, Tainer JA, Getzoff ED, Boulianne GL, Kirby K, Hilliker AJ: Subunit-destabilizing mutations in Drosophila copper/zinc superoxide dismutase: neuropathology and a model of dimer dysequilibrium. Proc Natl Acad Sci USA 1995, 92:8574-8578.
13. Perutz MF: Glutamine repeats and inherited neurodegenerative diseases: molecular aspects. Curr Opin Struct Biol 1996, 6:848-858.
14. Ross CA: Intranuclear neuronal inclusions: a common pathogenic mechanism for glutamine-repeat neurodegenerative diseases? Neuron 1997, 19:1147-1150.
15. Karlin S, Burge C: Trinucleotide repeats and long homopeptides in genes and proteins associated with nervous system disease and development. Proc Natl Acad Sci USA 1996, 93:1560-1565.
16. Michalakis Y, Veuille M : Length variation of CAG/ CAA trinucleotide repeats in natural populations of Drosophila melanogaster and its relation to the recombination rate. Genetics 1996, 143:1713-1725.
17. Warrick JM, Paulson HL, Gray-Board GL, Bui QT, Fischbeck KH, Pittman RN, Bonini NM: Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in Drosophila. Cell 1998, 93:939-949.
18. Coombe PE, Heisenberg M: The structural brain mutant Vacuolar medulla of Drosophila melanogaster with specific behavioral defects and cell degeneration in the adult. J Neurogenet 1986, 3:135-158.
19. Adams CM, Anderson MG, Motto DG, Price MP, Johson WA, Welsh MJ: Ripped pocket and pickpocket, novel Drosophila DEG ENaC subunits expressed in early development and in mechanosensory neurons. J Cell Biol 1998, 140:143-152.
20. Boulianne GL, Livne-Bar I, Humphreys JM, Liang Y, Lin C, Rogaev E, St George-Hyslop P: Cloning and characterization of the Drosophila presenilin homologue. Neuroreport 1997, 8:1025-1029.
21. Hong CS, Koo EH: Isolation and characterization of Drosophila presenilin homolog. Neuroreport 1997, 8:665-668.