The in vivo mutagenicity and mutational spectrum at the lacI transgene recovered from the spleens of B6C3F1 lacI transgenic mice following a 4-week inhalation exposure to 1,3-butadiene

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 401, Issue 1-2, 1998, Pages 99-110

  Recio, Leslie ^a   Pluta, Linda J ^a   Meyer, Kathy G ^a  

^a CIIT CENTERS FOR HEALTH RESEARCH   (United States)

Author keywords

1,3 Butadiene; LacI transgenic mouse; Mutational spectrum; Spleen

Indexed keywords

1,3 BUTADIENE;

AIR POLLUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENICITY; CONTROLLED STUDY; MOUSE; MUTAGENICITY; MUTATION RATE; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; PRIORITY JOURNAL; RUBBER INDUSTRY; SPLEEN; TRANSGENIC MOUSE;

ADMINISTRATION, INHALATION; ANIMALS; BACTERIAL PROTEINS; BUTADIENES; DNA TRANSPOSABLE ELEMENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; ESCHERICHIA COLI PROTEINS; MICE; MICE, INBRED STRAINS; MICE, TRANSGENIC; MUTAGENICITY TESTS; MUTAGENS; POINT MUTATION; REPRESSOR PROTEINS; SEQUENCE DELETION;

ANIMALIA; MUS MUSCULUS;

EID: 0032486077     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(97)00319-9     Document Type: Article

References (47)

1. Chemical Week, Butadiene, market and economics/product focus, Chem. Week, August 7, 1996, 32.
2. Chemical Engineering News, Top 50 chemical production rose modestly last year, Chem. Eng. News, April 11, 1994, 2-16.
3. U.S. Environmental Protection Agency (EPA), Cancer Risk from Outdoor Exposure to Air Toxics, Appendices (EPA-4501/1-90-004b), Washington, DC (1990) 2.
4. National Toxicology Program (NTP), Toxicology and Carcinogenesis Studies of 1,3-Butadiene in B6C3F1 Mice (Inhalation Studies), Technical Report No. 228, National Toxicology Program, Research Triangle Park, NC (1984).
5. J.E. Huff, R.L. Melnick, H.A. Solleveld, J.K. Haseman, M. Powers, R.A. Miller, Multiple organ carcinogenicity of 1,3-butadiene in B6C3F1 mice after 60 weeks of inhalation exposure, Science 227 (1985) 548-549.
6. R.L. Melnick, J. Huff, B.J. Chou, R.A. Miller, Carcinogenicity of 1,3-butadiene in B6C3F1 mice at low exposure concentrations, Cancer Res. 50 (1990) 6592-6599.
7. R.L. Melnick, J.E. Huff, J.H. Roycroft, B.J. Chou, R.A. Miller, Inhalation toxicology and carcinogenicity of 1,3-butadiene in B6C3F1 mice following 65 weeks of exposure, Environ. Health Perspect. 86 (1990) 27-36.
8. P.E. Owen, J.R. Glaister, Inhalation toxicity and carcinogenicity of 1,3-butadiene in Sprague-Dawley rats, Environ. Health Perspect. 86 (1990) 19-25.
9. I.-D. Adler, J. Cochrane, S. Osterman-Golkar, T.R. Skopek, M. Sorsa, E. Vogel, 1,3-Butadiene working group report, Mutation Res. 330 (1995) 101-114.
10. D. Jacobson-Kram, S.L. Rosenthal, Molecular and genetic toxicology of 1,3-butadiene, Mutation Res. 339 (1995) 121-130.
11. R.L. Melnick, M.C. Kohn, Mechanistic data indicate that 1,3-butadiene is a human carcinogen, Carcinogenesis 16 (1995) 157-163.
12. J.A. Bond, L. Recio, D. Andjelkovich, Epidemiological and mechanistic data suggest that 1,3-butadiene will not be carcinogenic to humans at exposures likely to be encountered in the environment or workplace, Carcinogenesis 16 (1995) 165-171.
13. M. Sorsa, K. Peltonen, D. Anderson, N.A. Demopoulos, H.-G. Neumann, S. Osterman-Golkar, Assessment of environmental and occupational exposures to butadiene as a model for risk estimation of petrochemical emissions, Mutagenesis 11 (1996) 9-17.
14. E. Löser, W.F. Tordior, Evaluation of butadiene and isoprene health risks, Proceedings of the International Symposium, Toxicology, 113 (1996).
15. M.W. Himmelstein, J.F. Acquavella, L. Recio, M.A. Medinsky, J.A. Bond, Toxicology and epidemiology of 1,3-butadiene, Crit. Rev. Toxicol. 27 (1996) 1-108.
16. International Agency for Research on Cancer (IARC), 1,3-Butadiene, IARC Monographs on the Evaluation of Carcinogenic Risk to Humans, 54 (1992) 237-285, Occupational Exposures to Mists and Vapours from Strong Inorganic Acids; and Other Industrial Chemicals, IARC, Lyon, France.
17. International Agency for Research on Cancer (IARC), 1,3- Butadiene, IARC Monographs on the Evaluation of Carcinogenic Risk to Humans, 54 (1992) 237-285, Occupational Exposures to Mists and Vapours from Strong Inorganic Acids; and Other Industrial Chemicals, IARC, Lyon, France.
18. E. Delzell, N. Sathiakumar, M. Hovinga, M. Macaluso, J. Julian, R. Larson, P. Cole, D.C.F. Muir, A follow-up study of synthetic rubber workers, Toxicology 113 (1996) 182-189.
19. M. Macaluso, R. Larson, E. Delzell, N. Sathiakumar, M. Hovinga, J. Julian, D. Muir, P. Cole, Leukemia and cumulative exposure to butadiene, styrene and benzene among workers in the synthetic rubber industry, Toxicology 113 (1996) 190-202.
20. 13C]butadiene, Chem. Res. Toxicol. 9 (1996) 689-695.
21. M.W. Himmelstein, M.J. Turner, B. Asgharian, J.A. Bond, Comparison of blood concentrations of 1,3-butadiene and butadiene epoxides in mice and rats exposed to 1,3-butadiene by inhalation, Carcinogenesis 15 (1994) 1479-1486.
22. M.J. Seaton, M.H. Follansbee, J.A. Bond, Oxidation of 1,2-epoxy-3-butene to 1,2:3,4-diepoxybutane by cDNA-expressed human cytochrome P450 2E1 and 3A4 and human, mouse, and rat liver microsomes, Carcinogenesis 16 (1995) 2287-2292.
23. J.E. Cochrane, T.R. Skopek, Mutagenicity of butadiene and its epoxide metabolites: I. Mutagenic potential of 1,2-epoxybutene, 1,2,3,4-diepoxybutane and 3,4-epoxy-1,2-butanediol in cultured human lymphoblasts, Carcinogenesis 15 (1994) 713-717.
24. I.-D. Adler, J.G. Filser, P. Gassner, W. Kessler, J. Schöneich, G. Schriever-Schwemmer, Heritable translocations induced by exposure of male mice to 1,3-butadiene, Mutation Res. 347 (1995) 121-127.
25. M.J. Cunningham, W.N. Choy, G.T. Arce, L.B. Rickard, D.A. Vlachos, L.A. Kinney, A.M. Sariff, In vivo sister chromatid exchange and micronucleus induction studies with 1,3-butadiene in B6C3F1 mice and Sprague-Dawley rats, Mutagenesis 1 (1986) 449-452.
26. K. Autio, L. Renzi, J. Catalan, O.E. Albrecht, M. Sorsa, Induction of micronuclei in peripheral blood and bone marrow erythrocytes of rats and mice exposed to 1,3-butadiene by inhalation, Mutat. Res. 309 (1994) 315-320.
27. J.E. Cochrane, T.R. Skopek, Mutagenicity of butadiene and its epoxide metabolites: II. Mutational spectra of butadiene, 1,2-epoxybutene and diepoxybutane at the hprt locus in splenic T cells from exposed B6C3F1 mice, Carcinogenesis 15 (1994) 719-723.
28. A.D. Tales, F.J. van Dam, F.A. de Zwart, C.M.M. van Teylingen, A.T. Natarajan, Development of a cloning assay with high cloning efficiency to detect induction of 6-thioguanine-resistant lymphocytes in spleen of adult mice following in vivo inhalation exposure to 1,3-butadiene, Mutation Res. 309 (1994) 299-306.
29. S. Sisk, L.J. Pluta, J.A. Bond, L. Recio, Molecular analysis of lacI mutants from bone marrow of B6C3F1 transgenic mice following inhalation exposure to 1,3-butadiene, Carcinogenesis 15 (1994) 471-477.
30. I.-D. Adler, D. Anderson, Dominant lethal effects after inhalation exposure to 1,3-butadiene, Mutation Res. 309 (1994) 295-297.
31. I.-D. Adler, J. Cao, J.G. Filser, P. Gassner, W. Kessler, U. Kleisch, A. Neuhäuser-Klaus, M. Nüsse, Mutagenicity of 1,3-butadiene inhalation in somatic and germinal cells of mice, Mutation Res. 309 (1994) 307-314.
32. L. Recio, K. Meyer, Increased frequency of mutations at A:T base pairs in the bone marrow of B6C3F1 lacI transgenic mice exposed to 1,3-butadiene, Environ. Mol. Mutagen. 26 (1995) 1-8.
33. S.C. Sisk, L.J. Pluta, K.G. Meyer, B.C. Wong, L. Recio, Assessment of the in vivo mutagenicity of ethylene oxide in the tissues of B6C3F1 lacI transgenic mice following inhalation exposure, Mutation Res. 391 (1997) 153-169.
34. P.J. Farabaugh, U. Schmeissner, M. Hofer, J.H. Miller, Genetic studies of the lacI repressor, J. Mol. Biol. 126 (1978) 847-863.
35. J.D. Callahan, J.M. Short, Transgenic λ/lacI mutagenicity assay: statistical determination of sample size, Mutation Res. 327 (1995) 201-208.
36. S.E. Kohler, G.S. Provost, A. Freck, P.L. Kretz, W.O. Bullock, J.A. Sorge, D.L. Putman, J. Short, Spectra of spontaneous and mutagen-induced mutations in the lad gene in transgenic mice, Proc. Natl. Acad. Sci. U.S.A. 88 (1991) 7958-7962.
37. L. Recio, K.G. Meyer, L.J. Pluta, O.R. Moss, C.J. Saranko, Assessment of 1,3-butadiene mutagenicity in the bone marrow of B6C3F1 lacI transgenic mice (Big Blue®): a review of mutational spectrum and lad mutant frequency after a 5-day 625 ppm 1,3-butadiene exposure, Environ. Mol. Mutagen. 28 (1996) 424-429.
38. J.G. de Boer, S. Provost, N. Gorelick, K. Tindall, B.W. Glickman, Spontaneous mutation in lad transgenic mice: a comparison of tissues, Mutagenesis (1997), in press.
39. L. Citti, P.G. Gervasi, G. Turchi, G. Bellucci, R. Bianchini, The reaction of 3,4-epoxy-1-butene with deoxyguanosine and DNA in vitro: synthesis and characterization of the main adducts, Carcinogenesis 5 (1984) 47-52.
40. 6-adenine adducts, Carcinogenesis 16 (1995) 2999-3007.
41. 7-guanine residues in vivo after 1,3-butadiene inhalation exposure, Carcinogenesis 18 (1997) 439-443.
42. 32P-postlabelling, Carcinogenesis 15 (1994) 1903-1910.
43. I. Neagu, P. Koivisto, C. Neagu, R. Kostiainen, K. Stenby, K. Peltonen, Butadiene monoxide and deoxyguanosine alkylation products at the N7-position, Carcinogenesis 16 (1995) 1809-1813.
44. 7-guanosine adducts of butadiene monoxide, Chem. Res. Toxicol. 9 (1995) 126-132.
45. N.Y. Tretyakova, Y.-P. Lin, P.B. Upton, R. Sangaiah, J.A. Swenberg, Macromolecular adducts of butadiene, Toxicology 113 (1996) 70-76.
46. N. Tretyakova, Y.-P. Lin, R. Sangaiah, P. Upton, J.A. Swenberg, Identification and quantitation of DNA adducts from calf thymus DNA exposed to 3,4-epoxy-1-butene, Carcinogenesis 18 (1997) 137-147.
47. R.R. Tice, R. Boucher, C.A. Luke, M.D. Shelby, Comparative cytogenetic analysis of bone marrow damage induced in male B6C3F1 mice by multiple exposures to gaseous 1,3-butadiene, Environ. Mutagen. 9 (1987) 235-250.