Primer-template misalignments during leading strand DNA synthesis account for the most frequent spontaneous mutations in a quasipalindromic region in Escherichia coli

Journal of Molecular Biology

Volumn 284, Issue 3, 1998, Pages 633-646

  Rosche, William A ^a,c   Ripley, Lynn S ^b   Sinden, Richard R ^a  

^a TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

^b RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^c BOSTON UNIVERSITY SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

DNA replication; Duplication mutation; Intermolecular strand switch; Quasipalindrome; Spontaneous DNA secondary structure mutagenesis

Indexed keywords

PALINDROMIC DNA;

ARTICLE; CONTROLLED STUDY; DNA SEQUENCE; DNA STRAND; DNA SYNTHESIS; ESCHERICHIA COLI; FRAMESHIFT MUTATION; GENE MUTATION; MUTATION RATE; NONHUMAN; PLASMID; PRIORITY JOURNAL; REPORTER GENE;

ESCHERICHIA COLI; FELIS CATUS; NEGIBACTERIA;

EID: 0032484153     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1998.2193     Document Type: Article

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