Restored humoral immune response to influenza vaccination in HIV-infected adults treated with highly active antiretroviral therapy

AIDS

Volumn 12, Issue 17, 1998, Pages

  Kroon, Frank P ^a   Rimmelzwaan, Guus F ^b   Roos, Marijke T L ^c,d   Osterhaus, Ab D M E ^b   Hamann, Dörte ^c,d   Miedema, Frank ^c,d,e   Van Dissel, Jaap T ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

^c CENTRAL LABORATORY   (Netherlands)

^d UNIVERSITY OF AMSTERDAM   (Netherlands)

^e ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

Highly active antiretroviral therapy; HIV; Immunologic reconstitution; Influenza vaccination

Indexed keywords

ANTIRETROVIRUS AGENT; CD4 ANTIGEN; INFLUENZA VACCINE; VIRUS ANTIBODY;

ADULT; ANTIBODY RESPONSE; ANTIBODY TITER; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HEMAGGLUTINATION INHIBITION TEST; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMORAL IMMUNITY; INFLUENZA VACCINATION; LYMPHOCYTE SUBPOPULATION; MALE; PRIORITY JOURNAL; T LYMPHOCYTE; VIRUS LOAD;

EID: 0032480989     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002030-199817000-00002     Document Type: Article

References (21)

1. Lane HC, Depper JM, Greene WC, Whalen C, Waldmann TA, Fauci AS: Qualitative analysis of immune function in patients with the acquired immunodeficiency syndrome. Evidence for a selective defect in soluble antigen recognition. N Engl J Med 1985, 313:79-84.
2. Kroon FP, van Dissel JT, de Jong JC, van Furth R: Antibody response to influenza, tetanus and pneumococcal vaccines in HIV-seropositive individuals in relation to the number of CD4+ lymphocytes. AIDS 1994, 8:469-476.
3. Kroon FP, van Dissel JT, Labadie J, van Loon AM, van Furth R: Antibody response to diphtheria, tetanus and poliomyelitis vaccines in relation to the number of CD4+ T lymphocytes in adults infected with human immunodeficiency virus. Clin Infect Dis 1995, 21:1197-1203.
4. Fauci AS: Multifactorial nature of human immunodeficiency virus disease: implications for therapy. Science 1993, 262:1011-1018.
5. Miedema F, Meyaard L, Koot M, et al.: Changing virus-host interactions in the course of HIV-1 infection. Immunolog Rev 1994, 140:35-72.
6. Palella Jr FJ, Delaney KM, Moorman AC, et al.: Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. N Engl J Med 1998, 338:853-860.
7. Autran B, Carcelain G, Li TS, et al.: Positive effects of combined antiretroviral therapy on CD4+ T cell homeostasis and function in advanced HIV disease. Science 1997, 277:112-116.
8. Pakker NG, Notermans DW, Boer de RJ, et al.: Biphasic kinetics of peripheral blood T cells after triple combination therapy in HIV-1 infection: A composite of redistribution and proliferation. Nature Med 1998, 4:208-214.
9. Connors M, Kovacs JA, Krevat S, et al.: HIV infection induces changes in CD4+ T-cell phenotype and depletions within the CD4+ T-cell repertoire that are not immediately restored by antiviral or immune-based therapies. Nature Med 1997, 3:533-540.
10. Gorochov G, Neumann AU, Kereveur A, et al.: Perturbation of CD4+ and CD8+ T-cell repertoires during progression to AIDS and regulation of the CD4+ repertoire during antiviral therapy. Nature Med 1998, 4:215-221.
11. Masurel N, Ophof P, de Jong P.: Antibody response to immunization with influenza A/USSR/77 (H1N1) virus in young individuals primed or unprimed for A/New Jersey/76 (H1N1) virus. J Hygiene 1981, 87:201-209.
12. Hamann D, Baars PA, Rep MHG, et al.: Phenotypic and functional separation of memory and effector human CD8+ T cells. J Exp Med 1997, 186:1407-1418.
13. Zhang ZQ, Notermans DW, Sedgewick G, et al.: Kinetics of CD4+ T cell repopulation of lymphoid tissues after treatment of HIV-1 infection. Proc Natl Acad Sci USA 1998, 95:1154-1159.
14. Connick E, Lederman M, Kotzin B, et al.: Immunologic effects of 48 weeks of AZT/3TC/Ritonavir. 5th Conference on Retroviruses and Opportunistic Infections. Chicago, February 1998 [abstract: late breaker 14].
15. Carcelain C, Li TS, Leibowitch J, et al.: Anti-retroviral therapies in advanced patients can restore CD4 T cell functions. 13th European Immunology Meeting. Amsterdam, June 1997 [abstract P.4.04.16].
16. Hicks CB, Markert L, Ottinger J, et al.: Immunologic changes in blood and lymph nodes induced hy highly active antiretroviral therapy (HAART). 5th Conference on Retroviruses and Opportunistic Infections. Chicago, February 1998 [abstract 21].
17. Liebmann J, Huang X, Fan Z, et al.: Highly active antiretroviral therapy (HAART) results in delayed enhancement of CD4+ T cell reactivity to mitogen and recall antigens, but not HIV-1 antigens. 5th Conference on Retroviruses and Opportunistic Infections. Chicago, February, 1998 [abstract 169].
18. Angel JB, Kumar A, Parato K, et al.: Improvement in cell-mediated immune function during potent anti-human immunodeficiency virus therapy with ritonavir plus saquinavir. J Infect Dis 1998, 177:898-904.
19. Li TS, Tubiana R, Katlama C, Calvez V, Mohand HA, Autran B: Long-lasting recovery in CD4 T-cell function and viral-load reduction after highly active antiretroviral therapy in advanced HIV-1 disease. Lancet 1998, 351:1682-1686.
20. Russell SM, Liew FY: T cells primed by influenza virion internal components can cooperate in the antibody response to haemagglutinin. Nature 1979, 280:147-148.
21. Lamb JR, Eckels DD, Phelan M, Lake P, Woody JN: Antigen-specific human T-lymphocyte clones: viral antigen specificity of influenza virus-immune clones. J Immunol 1982, 128:1428-1432.