Cell density-dependent regulation of fibronectin splicing at the EDA region in fibroblasts: Cell density also modulates the responses of fibroblasts to TGF-β and cancer cell-conditioned medium

Cancer Letters

Volumn 129, Issue 1, 1998, Pages 45-54

  Inoue, Teruhiko ^a   Nabeshima, Kazuki ^a   Shimao, Yoshiya ^a   Kataoka, Hiroaki ^a   Koono, Masashi ^a  

^a UNIVERSITY OF MIYAZAKI   (Japan)

Author keywords

Cancer; Cell cell interaction; Fibronectin; Splicing; TGF

Indexed keywords

EDOXUDINE; FIBRONECTIN; MESSENGER RNA; TRANSFORMING GROWTH FACTOR BETA;

ARTICLE; CELL DENSITY; CONTROLLED STUDY; CULTURE MEDIUM; FIBROBLAST CULTURE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; RNA SPLICING;

ADENOCARCINOMA; ALTERNATIVE SPLICING; BASE SEQUENCE; CULTURE MEDIA, CONDITIONED; DNA PRIMERS; FIBROBLASTS; FIBRONECTINS; GENE EXPRESSION REGULATION; HUMANS; RECTAL NEOPLASMS; RNA, MESSENGER; TRANSFORMING GROWTH FACTOR BETA;

EID: 0032479543     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(98)00079-2     Document Type: Article

References (36)

1. R.O. Hynes, Fibronectins, Springer, New York, 1990.
2. Ruoslahti E. Structure and biology of proteoglycans. Ann. Cell Biol. 4:1988;229-255.
3. ffrench-Constant C., Hynes R.O. Alternative splicing of fibronectin is temporally and spatially regulated in the chicken embryo. Development. 106:1989;375-388.
4. Kaczmarek J., Castellani P., Nicolo G., Spina B., Allemanni G., Zardi L. Distribution of oncofetal fibronectin isoforms in normal hyperplastic and neoplastic human breast tissues. Int. J. Cancer. 58:1994;11-16.
5. Brown L.F., Dubin D., Lavigne L., Logan B., Dvorak H.F., Van De Water L. Macrophages and fibroblasts express embryonic fibronectins during cutaneous wound healing. Am. J. Pathol. 142:1993;793-801.
6. ffrench-Constant C., Van De Water L., Dvorak H.F., Hynes R.O. Reappearance of an embryonic pattern of fibronectin during wound healing in the adult rat. J. Cell Biol. 109:1989;903-914.
7. Carnemolla B., Balza E., Siri A., Zardi L., Nicotra M.R., Bigotti A., Natali G.P. A tumor-associated fibronectin isoform generated by alternative splicing of messenger RNA precursors. J. Cell Biol. 108:1989;139-148.
8. Hauptmann S., Zardi L., Siri A., Carnemolla B., Borsi L., Castellucci M., Klosterhalfen B., Hartung P., Weis J., Stocker G., Haubeck H.D., Kirkpatrick J. Extracellular matrix proteins in colorectal carcinomas. Expression of tenascin and fibronectin isoforms. Lab. Invest. 73:1995;172-182.
9. Lohi J., Tani T., Laitinen L., Kangas L., Lehto V.-P., Virtanen I. Tenascin and fibronectin isoforms in human renal cell carcinomas, renal cell carcinoma cell lines and xenografts in nude mice. Int. J. Cancer. 63:1995;442-449.
10. Oyama F., Hirohashi S., Shimosato Y., Titani K., Sekiguchi K. Oncodevelopmental regulation of the alternative splicing of fibronectin pre-messenger RNA in human lung tissues. Cancer Res. 50:1990;1075-1078.
11. Oyama F., Hirohashi S., Sakamoto M., Titani K., Sekiguchi K. Coordinate oncodevelopmental modulation of alternative splicing of fibronectin pre-messenger RNA at ED-A, ED-B, and CS1 regions in human liver tumors. Cancer Res. 53:1993;2005-2011.
12. Tavian D., De Pertro G., Colombi M., Portolani N., Giulini S.M., Gardella R., Barlati S. RT-PCR detection of fibronectin EDA+ and EDB+ mRNA isoforms: molecular markers for hepatocellular carcinoma. Int. J. Cancer. 56:1994;820-825.
13. Manabe R., Ohe N., Maeda T., Fukuda T., Sekiguchi K. Modulation of cell-adhesive activity of fibronectin by the alternatively spliced EDA segment. J. Cell Biol. 139:1997;295-307.
14. Balza E., Borsi L., Allemanni G., Zardi L. Transforming growth factor β regulates the levels of different fibronectin isoforms in normal human cultured fibroblasts. FEBS Lett. 228:1988;42-44.
15. Borsi L., Castellani P., Risso A.M., Leprini A., Zardi L. Transforming growth facter β regulates the splicing pattern of fibronectin messenger RNA precursor. FEBS Lett. 261:1990;175-178.
16. Magnuson V.L., Youn M., Schattenberg D.G., Mancini M.A., Cen D., Steffensen B., Klebe R.J. The alternative splicing of fibronectin pre-mRNA is altered during aging and in response to growth factors. J. Biol. Chem. 266:1991;14654-14662.
17. Inoue T., Nabeshima K., Shimao Y., Kataoka H., Koono M. Modulation of fibronectin synthesis by cancer cell-fibroblast interaction: cancer cells stimulate fibronectin production and affect alternative splicing of fibronectin pre-mRNA at EDA region in fibroblasts. Int. J. Oncol. 9:1996;721-730.
18. Kurogi T., Nabeshima K., Kataoka H., Okada Y., Koono M. Stimulation of gelatinase B and tissue inhibitor of metalloproteinase (TIMP) production in co-culture of human osteosarcoma cells and human fibroblasts: gelatinase B production was stimulated via up-regulation of fibroblast growth factor (FGF) receptor. Int. J. Cancer. 66:1996;82-90.
19. Kataoka H., Nabeshima K., Komada N., Koono M. New human colorectal carcinoma cell lines that secrete proteinase inhibitors in vitro. Virchows Arch. (B). 57:1989;157-165.
20. Singh R.K., Llansa N., Bucana C.D., Sanchez R., Koura A., Fidler I.J. Cell density-dependent regulation of basic fibroblast growth factor expression in human renal cell carcinoma cells. Cell Growth Diff. 7:1996;397-404.
21. Koura A.N., Liu W., Kitadai Y., Singh R.K., Radinsky R., Ellis L.M. Regulation of vascular endothelial growth factor expression in human colon carcinoma cells by cell density. Cancer Res. 56:1996;3891-3894.
22. Seslar S., Nakamura T., Byers S. Tumor-stroma interactions and stroma cell density regulate hepatocyte growth factor protein levels: a role for transforming growth factor-β activation. Endocrinology. 136:1995;1945-1953.
23. Johnson-Wint B. Regulation of stromal cell collagenase production in adult rabbit cornea: in vitro stimulation and inhibition by epithelial cell products. Proc. Natl. Acad. Sci. USA. 77:1980;5331-5335.
24. Xie B., Bucana C.D., Fidler I.J. Density-dependent induction of 92-kd type IV collagenase activity in cultures of A431 human epidermoid carcinoma cells. Am. J. Pathol. 144:1994;1058-1067.
25. Nabeshima K., Kishi J., Kurogi T., Komada N., Kataoka H., Okada Y., Koono M. Stimulation of TIMP-1 and metalloproteinase production in co-cultures of human tumor cells and human fibroblasts. Cancer Lett. 78:1994;133-140.
26. Wolthuis A., Boes A., Grond J. Cell density modulates growth, extracellular matrix, and protein synthesis of cultured rat mesangial cells. Am. J. Pathol. 143:1993;1209-1219.
27. Brown K.E., Lawrence R., Sonnenshein G.E. Concerted modulation of α1(XI) and α2(V) collagen mRNAs in bovine vascular smooth muscle cells. J. Biol. Chem. 266:1991;23268-23273.
28. Choi A.M.K., Olsen D.R., Cook K.G., Deamond S.F., Uitto J., Bruce S.A. Differential extracellular matrix gene expression by fibroblasts during their proliferative life span in vitro and at senescence. J. Cell Physiol. 151:1992;147-155.
29. Perkinson R.A., Kuo B.A., Norton P.A. Modulation of transcription of the rat fibronectin gene by cell density. J. Cell. Biochem. 63:1996;74-85.
30. Raghow R., Kang A.H., Pidikiti D. Phenotypic plasticity of extracellular matrix gene expression in cultured hamster lung fibroblasts. J. Biol. Chem. 262:1987;8409-8415.
31. Senger D.R., Destree A.T., Hynes R.O. Complex regulation of fibronectin synthesis by cells in culture. Am. J. Physiol. 245:1983;C144-C150.
32. Burke E.M., Danner D.B. Changes in fibronectin mRNA splicing with in vitro passage. Biochem. Biophys. Res. Commun. 178:1991;620-624.
33. Kumazaki T., Robertorye R.S., Robertorye S.C., Smith J.R. Fibronectin expression increases during in vitro cellular senescence: correlation with increased cell area. Exp. Cell Res. 195:1991;13-19.
34. Berndt A., Kosmehl H., Mandel U., Gabler U., Luo X., Celeda D., Zardi L., Katenkamp D. TGFβ and bFGF synthesis and localization in Dupuytren's disease (nodular palmar fibromatosis) relative to cellular activity, myofibroblast phenotype and oncofetal variants of fibronectin. Histochem. J. 27:1995;1014-1020.
35. Rizzino A., Kazakoff P., Ruff E., Kuszynski C., Nebelsick J. Regulatory effects of cell density on the binding of transforming growth factor-β, epidermal growth factor, platelet-derived growth factor, and fibroblast growth factor. Cancer Res. 48:1988;4266-4271.
36. Paulsson Y., Karlsson C., Heldin C.H., Westermark B. Density-dependent inhibitory effect of transforming growth factor-β1 on human fibroblasts involves the down-regulation of platelet-derived growth factor α-receptors. J. Cell Physiol. 157:1993;97-103.