Cleavage efficiency of the novel aspartic protease yapsin 1 (Yap3p) enhanced for substrates with arginine residues flanking the P1 site: Correlation with electronegative active-site pockets predicted by molecular modeling

Biochemistry

Volumn 37, Issue 9, 1998, Pages 2768-2777

  Olsen, Vicki ^c   Guruprasad, Kunchur ^a   Cawley, Niamh X ^c   Chen, Hao Chia ^c   Blundell, Tom L ^a   Loh, Y Peng ^b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; ASPARTIC PROTEINASE; ENDOTHIAPEPSIN; RHIZOPUSPEPSIN; UNCLASSIFIED DRUG; YAPSIN 1;

AMINO ACID SUBSTITUTION; ARTICLE; DNA FLANKING REGION; ELECTRICITY; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; MOLECULAR MODEL; NONHUMAN; PREDICTION; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE;

ALANINE; AMINO ACID SEQUENCE; ANIMALS; ARGININE; ASPARTIC ENDOPEPTIDASES; BINDING SITES; CHOLECYSTOKININ; KINETICS; LYSINE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; RATS; SEQUENCE ALIGNMENT;

EID: 0032478123     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9724826     Document Type: Article

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