Synthesis and anticholinesterase activity of huperzine a analogues containing phenol and catechol replacements for the pyridone ring

Bioorganic and Medicinal Chemistry Letters

Volumn 8, Issue 11, 1998, Pages 1413-1418

  Campiani, Giuseppe ^a   Kozikowski, Alan P ^b   Wang, Shaomeng ^b   Ming, Liu ^b   Nacci, Vito ^a   Saxena, Ashima ^c   Doctor, Bhupendra P ^c  

^a UNIVERSITY OF SIENA   (Italy)

^b GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

^c WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATECHOL DERIVATIVE; DRUG ANALOG; HUPERZINE A; PHENOL DERIVATIVE;

AMINO ACID SUBSTITUTION; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CHOLINESTERASE INHIBITION; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; DRUG DESIGN; DRUG SYNTHESIS; FETUS; NONHUMAN; STRUCTURE ANALYSIS; X RAY ANALYSIS;

ANIMALS; CATALYSIS; CATECHOLS; CATTLE; CHOLINESTERASE INHIBITORS; CRYSTALLOGRAPHY, X-RAY; HYDROGEN BONDING; MODELS, MOLECULAR; PALLADIUM; PHENOLS; PYRIDONES; SESQUITERPENES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0032474510     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(98)00229-7     Document Type: Article

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