Oral irritant effects of nicotine: Psychophysical evidence for decreased sensation following repeated application of and lack of cross-desensitization to capsaicin

Annals of the New York Academy of Sciences

Volumn 855, Issue , 1998, Pages 828-830

  Dessirier, Jean Marc ^a,b   O'Mahony, Michael ^a   Carstens, E ^b  

^a Department of Food Science ^*  (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAPSAICIN; IRRITANT AGENT; NICOTINE; TOBACCO SMOKE;

CONFERENCE PAPER; CONTROLLED STUDY; DESENSITIZATION; HUMAN; HUMAN EXPERIMENT; MOUTH MUCOSA; NOCICEPTIVE RECEPTOR; NORMAL HUMAN; PSYCHOPHYSICS; SENSITIZATION; TASTE ACUITY; TONGUE; TRIGEMINAL NERVE;

CAPSICUM FRUTESCENS; NICOTIANA TABACUM; PIPER NIGRUM;

EID: 0032467666     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1998.tb10669.x     Document Type: Conference Paper

References (11)

1. 1. Deneris, E. S. et al. 1991. Pharmacological and functional diversity of neuronal nicotinic acetylcholine receptors. Trends Pharmacol. Sci. 12: 34-40.
2. 2. Green, B. G. 1989 Capsaicin sensitization and desensitization on the tongue produced by brief exposures to a low concentration. Neurosci. Lett. 107: 173-178.
3. 3. Green, B. G. 1993. Evidence that removal of capsaicin accelerates desensitization on the tongue. Neurosci. Lett. 150: 44-48.
4. 4. Green, B. G. 1996. Rapid recovery from capsaicin desensitization during recurrent stimulation. Pain 68: 245-253.
5. 5. Green, D. M. & J. A. Swets. 1966. Signal Detection Theory and Psychophysics. John Wiley. New York.
6. 6. Holzer, P. 1991. Capsaicin: Cellular targets, mechanisms of action, and selectivity for thin sensory neurons. Pharmacol. Rev. 43: 143-201.
7. 7. Karrer, T. & L. Bartoshuk. 1991. Capsaicin desensitization and recovery on the human tongue. Physiol. Behav. 49: 757-764.
8. 8. Kim, K.-O. & M. O'Mahony. 1998. A new approach to category scales of intensity. II. Use of d' values. J. Sens. Stud. 13: 251-267.
9. 9. Liu, L. & S. A. Simon. 1996. Capsaicin and nicotine both activate a subset of rat trigeminal ganglion neurons. Am. J. Physiol. Cell Physiol. 39: C1807-C1814.
10. 10. O'Mahony, M. 1992. Understanding discrimination tests: A user-friendly treatment of response bias, rating and ranking R-index tests, and their relationship to signal detection. J. Sens. Stud. 7: 1-47.
11. 11. Dessirier, J.-M., M. O'Mahony & E. Carstens. 1997. Oral irritant effects of nicotine: Psychophysical evidence for decreased sensation following repeated application and lack of cross-desensitization with capsaicin. Chem. Senses 22: 483-492.