Nitrate reductase alters 3-nitrotyrosine accumulation and cell cycle progression in LPS + IFN-γ-stimulated RAW 264.7 cells

Nitric Oxide - Biology and Chemistry

Volumn 2, Issue 5, 1998, Pages 366-374

  Kalns, John ^a   Parker, Jill ^a   Bruno, John ^a   Holwitt, Eric ^a   Piepmeier, Edward ^a   Kiel, Johnathan ^a  

^a Air Force Materiel Command   (United States)

Author keywords

Nitrate reductase; Nitrite; Nitrotyrosine; Peroxynitrite; RAW 264.7

Indexed keywords

3 NITROTYROSINE; DNA; GAMMA INTERFERON; LIPOPOLYSACCHARIDE; N(G) NITROARGININE METHYL ESTER; NITRATE; NITRATE REDUCTASE; NITRITE; POTASSIUM NITRATE;

ANIMAL CELL; ARTICLE; BARLEY; CELL ACTIVATION; CELL CYCLE; CONTROLLED STUDY; DNA CONTENT; FLOW CYTOMETRY; GENETIC TRANSFECTION; IMMUNOCYTOCHEMISTRY; INFLAMMATION; INJURY; MOUSE; NITRATION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL;

ANIMALIA; HORDEUM VULGARE SUBSP. VULGARE; MURINAE;

EID: 0032461839     PISSN: 10898603     EISSN: None     Source Type: Journal    
DOI: 10.1006/niox.1998.0191     Document Type: Article

References (21)

1. de Werra I., Jaccard C. et al. Cytokines, nitrite/nitrate, soluble tumor necrosis factor receptors, and procalcitonin concentrations: Comparisons in patients with septic shock, cardiogenic shock, and bacterial pneumonia. Crit. Care Med. 25:1997;607-613.
2. Smail N., Catania R. A.et al. Gut and liver: The organs responsible for increased nitric oxide production after trauma-hemorrhage and resuscitation. Arch Surg. 133:1998;399-405.
3. Doughty L., Carcillo J. A.et al. Plasma nitrite and nitrate concentrations and multiple organ failure in pediatric sepsis. Crit. Care Med. 26:1998;157-162.
4. Eiserich J., Hristova M., Cross C., Jones A., Freeman B., Halliwell B., van der Vliet A. Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils. Nature. 391:1998;393-397.
5. Mallozzi C., Di Stasi A. M.et al. Peroxynitrite modulates tyrosine-dependent signal transduction pathway of human erythrocyte band 3. FASEB J. 11:1997;1281-1290.
6. Darley Usmar V. M., Hogg N. et al. The simultaneous generation of superoxide and nitric oxide can initiate lipid peroxidation in human low density lipoprotein. Free Radical. Res. Commun. 17:1992;9-20.
7. Radi R., Beckman J. S.et al. Peroxynitrite-induced membrane lipid peroxidation: The cytotoxic potential of superoxide and nitric oxide. Arch. Biochem. Biophys. 288:1991;481-487.
8. Rubbo H., Radi R. et al. Nitric oxide regulation of superoxide and peroxynitrite-dependent lipid peroxidation. Formation of novel nitrogen-containing oxidized lipid derivatives. J. Biol. Chem. 269:1994;26066-26075.
9. Szabo C., Zingarelli B. et al. DNA strand breakage, activation of poly (ADP-ribose) synthetase, and cellular energy depletion are involved in the cytotoxicity of macrophages and smooth muscle cells exposed to peroxynitrite. Proc. Natl. Acad. Sci. USA. 93:1996;1753-1758.
10. Barker J. E., Bolanos J. P.et al. Glutathione protects astrocytes from peroxynitrite-mediated mitochondrial damage: Implications for neuronal/astrocytic trafficking and neurodegeneration. Dev. Neurosci. 18:1996;391-396.
11. Shi X., Rojanasakul Y. et al. Generation of thiyl and ascorbyl radicals in the reaction of peroxynitrite with thiols and ascorbate at physiological pH. J. Inorg. Biochem. 56:1994;77-86.
12. 2. Proc. Natl. Acad. Sci. USA. 93:1996;3377-3382.
13. Bruno J. G., Parker J. E., Kiel J. L. Plant nitrate reductase gene fragments enhance nitrite production in activated murine macrophage cell lines. Biochem. Biophys. Res. Commun. 201:1994;284-289.
14. x. Proc. Natl. Acad. Sci. USA. 94:1997;3211-3216.
15. Singer D. II, Kawka W. Expression of inducible nitric oxide synthase and nitrotyrosine in colonic epithelium in inflammatory bowel disease. Gastroenterology. 111:1996;871-885.
16. Good P. F., Werner P. et al. Evidence of neuronal oxidative damage in Alzheimer's disease. Am. J. Pathol. 149:1996;21-28.
17. Liu P., C. Hock E. et al. Formation of nitric oxide, superoxide, and peroxynitrite in myocardial ischemia-reperfusion injury in rats. Am. J. Physiol. 272:1997;H2327-H2336.
18. Yamakura F., Taka H. et al. Inactivation of human manganese-superoxide dismutase by peroxynitrite is caused by exclusive nitration of tyrosine 34 to 3-nitrotyrosine. J. Biol. Chem. 273:1998;14085-14089.
19. Haddad I. Y., Zhu S. et al. Nitration of surfactant protein A results in decreased ability to aggregate lipids. Am. J. Physiol. 270:1996;L281-L288.
20. Gow A. J., Duran D. et al. Effects of peroxynitrite-induced protein modifications on tyrosine phosphorylation and degradation. FEBS Lett. 385:1996;63-66.
21. Adam J. M., Ettelaie C. et al. Modification of tissue factor by peroxynitrite influences its procoagulant activity. FEBS Lett. 429:1998;347-350.