Contribution of cyclooxygenase-1 and cyclooxygenase-2 to prostanoid formation by human enterocytes stimulated by calcium ionophore and inflammatory agents

Prostaglandins and Other Lipid Mediators

Volumn 56, Issue 5-6, 1998, Pages 325-339

  Longo, Walter E ^a   Panesar, Ninder ^a   Mazuski, John ^a   Kaminski, Donald L ^a,b  

^a S Louis Univ Sch Med/Cardinal G   (United States)

^b Department of Surgery ^*  (United States)

Author keywords

Calcium ionophore; Cyclooxygenase 1; Cyclooxygenase 2; Enterocytes; Human; Inflammatory agents; Prostanoid formation

Indexed keywords

5 (4 FLUOROPHENYL) 1 [(4 METHYLSULFONYL)PHENYL] 3 TRIFLUOROMETHYLPYRAZOLE; ANTIINFLAMMATORY AGENT; CALCIUM IONOPHORE; CYCLOOXYGENASE 1 INHIBITOR; CYCLOOXYGENASE 2; INTERLEUKIN 1; LIPOPOLYSACCHARIDE; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; PROSTAGLANDIN SYNTHASE; PROSTANOID;

ARTICLE; CELL CULTURE; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; GASTROINTESTINAL GLAND; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; INTESTINE CELL; PROSTAGLANDIN METABOLISM; SPECTROPHOTOMETRY; STATISTICAL ANALYSIS;

CALCIMYCIN; CALCIUM; CELL LINE; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; DINOPROST; DINOPROSTONE; EICOSANOIDS; EPITHELIAL CELLS; HUMANS; IMMUNOBLOTTING; INTERLEUKIN-1; INTESTINES; ISOENZYMES; LIPOPOLYSACCHARIDES; MEMBRANE PROTEINS; NITROBENZENES; PROSTAGLANDIN D2; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROSTAGLANDINS; PYRAZOLES; SALICYLIC ACIDS; SULFONAMIDES; TETRADECANOYLPHORBOL ACETATE;

EID: 0032461407     PISSN: 00906980     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0090-6980(98)00058-6     Document Type: Article

References (48)

1. 1. Eberhart, C.E., Dubois, R.N. Eicosanoids and the gastrointestinal tract. Gastroenterol. 109:285; 1995.
2. 2. Kessler, W.F., Shires, G.T., Fahey, T.J. Surgical complications of nonsteroidal anti-inflammatory drug-induced small bowel ulceration. J Am Coll Surg. 185:250; 1997.
3. 3. Appleton, I., Tomlinson, A., Willoughby, D.A. Induction of cyclooxygenase and nitric oxide synthase in inflammation. Adv Pharmocol. 35:27.; 1996.
4. 4. Bakhle, Y.S., Botting, R.M. Cyclooxygenase-2 and its regulation in inflammation. Med Inflamm. 5:305; 1996.
5. 5. Eberhart, C.E., Coffey, R.J., Radhika, A., Giardiello, F.M., Ferrenbach, S., DuBois, R.N. Upregulation of cyclooxygenase-2 gene expression in human colorectal adenomas and adenocarcinomas. Gastroenterol. 107:1183; 1994.
6. 6. Kosaka, T., Miyata, A., Ihara, H., et al. Characterization of the human gene (PTGS2) encoding prostaglandin-endoperoxide synthase-2. Eur J Biochem. 221:889; 1994.
7. 7. Philbeam, C.C., Kawaguchi, H., Hadeda, Y., Voznesensky, O., Alander, C.B., Raisz, L.G. Differential regulation of inducible and constitutive prostaglandin endoperoxide synthase in osteoblastic MC3T3-E1 cells. J Biol Chem. 268: 25643; 1993.
8. 8. Hamasaki, Y., Kitzler, J., Hardman, R., Nettesheim, P., Eling, T.E. Phorbol ester and epidermal growth factor enhance the expression of two inducible prostaglandin H synthase genes in rat tracheal epithelial cells. Arch Biochem Biophys. 304:226; 1993.
9. 9. Hamasaki, Y., Eling, T.E. EGF and TPA stimulate de novo synthesis of PGHS-1 and PGHS-2 through different signal transduction pathways. Pros Leuk Ess Fatty Acids. 53:225; 1995.
10. 10. Zyglewska, T., Wu, L.C., Xu, X.M., Conlan, M.G., Wang, L.H., Wu, K.K. Quantitative analysis of vascular prostaglandin H synthase mRNA by competitive polymerase chain reaction (PCR). J Lab Clin Meth. 122:542; 1993.
11. 11. Jackson, B.A., Goldstein, R.H., Roy, R., Cozzani, M., Taylor, L., Polgar, P. Effects of transforming growth factor B and IL-1β on expression of cyclooxygenase 1 and 2 and phospholipase A2 in lung fibroblasts and endothelial cells in culture. Biochem Biophys Res Comm. 197:1465; 1993.
12. 12. Smith, C.J., Morrow, J.D., Roberts, L.J., Marnett, L.J. Differentiation of monocytoid THP-1 cells with phorbol ester induces expression of prostaglandin endoperoxide synthase-1 (COX-1). Biochem Biophys Res Comm. 192:787; 1993.
13. 13. Samet, J.M., Fasano, M.B., Fonteh, A.N., Chilton, F.H. Selective induction of prostaglandin G/H synthase I by stem cell factor and dexamethasone in mast cells. J Biol Chem. 270:8044; 1995.
14. 14. Seibert, K., Masferrer, J.L. Role of inducible cyclooxygenase (COX-2) in inflammation. Receptor. 4:17; 1994.
15. 15. Langenbach, R., Morham, S.G., Tiano, H.F., et al. Prostaglandin synthase-1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration. Cell. 83:483; 1995.
16. 16. Sano, H., Kawahito, Y., Wilder, R.L., et al. Expression of cyclooxygenase-1 and 2 in human colorectal cancer. Cancer Res. 55:3785; 1995.
17. 17. Kargman, S.L., O'Neill, G.P., Vickers, P.J., Jilly, F.E., Manlini, J.A., Jothy, S. Expression of prostaglandin G/H synthase-1 and-2 protein in human colorectal cancer. Cancer Res. 55:2556; 1995.
18. 18. Hampel, H., Muller, N. Inflammatory and immunological mechanisms in Alzheimer's disease. Drugs News Perspect. 8:599; 1995.
19. 19. Peplow, P.V. Actions of cytokines in relation to arachidonic acid metabolism and eicosanoid production. Pros Leuk and Ess Fatty Acids. 54:303; 1996.
20. 20. Meade, E.A., Smith, W.L., DeWitt, D.L. Differential inhibition of prostaglandin endoperoxide synthase (cyclooxygenase) isozymes by aspirin and other non-steroidal anti-inflammatory drugs. J Biol Chem. 268:6610; 1993.
21. 21. Mitchell, J.A., Akarasereennot, P., Thiemermann, C., Flower, C.J., Vane JR. Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase. Proc Natl Acad Sci. 90:11,693; 1994.
22. 22. Morita, I., Schindler, M., Reigier, M.K., Otto, J.C., Hori, T., DeWitt, D.L., Smith, W.L. Different intra-cellular locations for prostaglandin endoperoxide H synthase-1 and 2. J Biol Chem. 270:10,902; 1995.
23. 23. Karmen, S., Wong, E., Greig, G.M., et al. Mechanisms of selective inhibition of human prostaglandin G/H synthase-1 and 2 in intact cells. Biochem Pharm. 52:1113; 1996.
24. 24. Herschman, H.R. Regulation of prostaglandin synthase-1 and prostaglandin synthase-2. Cancer and Metastasis Review 13:241; 1994.
25. 25. Bhattacharyya, D.K., Lecomte, M., Dunn, J., Morgans, D.J., Smith, W.L. Selective inhibition of prostaglandin endoperoxide synthase-1 (cyclooxygenase-1) by valerylsalicyclic acid. Arch Biochem Biophys. 317:19; 1995.
26. 26. Seibert, K., Zhang, Y., Leahy, K., et al. Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain. Proc Natl Acad Sci. 91:12013; 1994.
27. 27. Futaki, N., Takahashi, S., Yokoyama, M., Arai, I., Higuchi, S., Otomo, S. NS-398, a new anti-inflammatory agent, selectively inhibits prostaglandin G/H synthase/cyclooxygenase (COX-2) activity in vitro. Prostaglandins. 47: 55; 1994.
28. 28. Huff, R., Collins, P., Kramer, S., et al. A structural feature of N-[2-(cyclohexyloxy)-4-nitrophenyl] methanesulfonamide (NS-398) that governs its selectivity and affinity for cyclooxygenase 2 (COX-2). Inflamm Res. 44(Supplement 2):s145; 1995.
29. 29. O'Sullivan, M.G., Huggins, E.M., Meade, E.A., DeWitt, D.L., McCall, C.E. Lipopolysaccharide induces prostaglandin H synthase-2 in alveolar macrophages. Biochem Biophys Res Commun. 187:1123; 1992.
30. 30. Lyons-Giordano, B., Pratta, M.A., Galbraith, W., Davis, G.L., Arner, E.C. IL-1 differentially modulates chondrocyte expression of cyclooxygenase-2 and phospholipase A2. Exp Cell Res. 206:58; 1993.
31. 31. Homaidan, F.R., Zhao, L., Burakoff, R. IL-1β induces synthesis of phospholipase A2 activating protein in rabbit distal colon. Am J Physiol. 272 (Gastrointest Liver Physiol 35):G1338; 1997.
32. ++-independent phospholipase A2 by methylarachidonyl fluorophosphonate. Bichem Biophys Acta. 1302:55; 1996.
33. ++ in HL 60 granulocytes. j Biol Chem. 267:25,966; 1992.
34. 34. Stratton, M.D., Sexe, R., Peterson, B., Kaminski, D.L., Li, A.P., Longo, W.E. The effects of trinitrobenzene sulfonic acid (TNB) on colonocyte arachidonic acid metabolism. J Surg Res. 60:375; 1996.
35. 35. Bradford, M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 72:248; 1976.
36. 36. Nag, M.K., Deshpande, Y.G., Beck, D., Li, A., Kaminski, D.L. The effect of lysolecithin on prostanoid and platelet-activating factor formation by human gallbladder mucosal cells. Med Inflamm. 4:90; 1995.
37. 37. Longo, W.E., Damore, L.J., Deshpande, Y., et al. The role of cyclooxygenase-1 and cyclooxygenase-2 in lipopolysaccharide and IL-1 stimulated enterocyte prostanoid formation. Mediators of Inflammation, 7:85; 1998.
38. 38. Smith, G.S., Rieckenberg, C., Longo, W.E., et al. The effect of an interleukin receptor antagonist on colonocyte eicosanoid release. Med Inflamm. 5:449; 1996.
39. 39. Damore, L.J., Longo, W.E., Rieckenberg, C.L., et al. The effect of proinflammatory agents on enterocyte arachidonic acid metabolism: Impact of a cyclooxygenase-2 inhibitor on cellular eicosanoid release. Surgical Forum XLVII: 190; 1996.
40. 40. Gustafson, C., Kald, B., Sjodahl, R., Tagesson, C. Phospholipase C from clostridium perfringens stimulates formation of platelet-activating factor (PAF-Acether) in cultured intestinal epithelial cells (INT 407). Scand J Gastroenterol. 26:1000; 1991.
41. 41. Parker, J., Kaplon, M.K., Alvarez, C.J., Krishnaswamy, G. Prostaglandin H synthase expression is variable in human colorectal adenocarcinoma cell lines. Exp Cell Res. 236:321; 1997.
42. 42. Murakami, M., Bingham, C.O., Matsumoto, R., Austen, K.F., Arm, J.P. IgE-dependent activation of cytokine-primed mouse cultured mast cells induces a delayed phase of prostaglandin D2 generation via prostaglandin endoperoxidase synthase-2. J Immunol. 155:4445; 1995.
43. 43. Murakami, M., Matsumoto, R., Austen, K.F., Arm, J.P. Prostaglandin endoperoxide synthase-1 and -2 couple to different transmembrane stimuli to generate prostaglandin D2 in mouse bone marrow-derived mast cells. J Biol Chem. 269:22,269; 1994.
44. 44. Gilbert, R.S., Reddy, S.T., Targan, S., Herschman, H.R. TGF-B1 augments expression of the T1S10/prostaglandin synthase-2 gene in intestinal epithelial cells. Cell and Molec Bio Res. 40:653; 1994.
45. 45. Kawata, R., Reddy, ST., Wolner, B., Herschman, H.R. Prostaglandin synthase-1 and prostaglandin synthase-2 both participate in activation-induced prostaglandin D2 production in mast cells. J Immunol. 155:818; 1995.
46. 46. Hudson, N., Hawthorne, A.B., Cole, A.T., Jones, P.D., Hawkey, C.J. Mechanisms of gastric and duodenal damage and protection. Hepatogastroenterol. 39(Suppl 1):31; 1992.
47. 47. Whittle, B.J.R., Vane, J.R. In: Physiology of the gastrointestinal tract. Prostanoids are regulators of gastrointestinal function. (L.R. Johnson, ed.). 2nd edition. Raven Press, New York. 1987, p. 143.
48. 48. Uribe, A., Alam, M., Midtvedt, T. E2 prostaglandins modulate cell proliferation in the small intestinal epithelium of the rat. Digestion. 52:157; 1992.