Role of A(2A) adenosine receptors in inflammation

Drug Development Research

Volumn 45, Issue 3-4, 1998, Pages 103-112

  Sullivan, Gail W ^a,b   Linden, Joel ^a,b  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

Author keywords

A(2A); Adenosine; Inflammation

Indexed keywords

2 CYCLOHEXYLMETHYLIDENEHYDRAZINOADENOSINE; 2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); 6 N (3 IODOBENZYL)ADENOSINE 5' N METHYLCARBOXAMIDE; ADENOSINE; ADENOSINE 5' (N ETHYLCARBOXAMIDE); ADENOSINE A2A RECEPTOR; ADENOSINE A2A RECEPTOR AGONIST; ADENOSINE RECEPTOR STIMULATING AGENT; BINODENOSON; CYCLIC AMP; INTERLEUKIN 2 RECEPTOR; REACTIVE OXYGEN METABOLITE; ROLIPRAM; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; BASOPHIL; CONFERENCE PAPER; DRUG RECEPTOR BINDING; EOSINOPHIL; HUMAN; INFLAMMATION; LYMPHOCYTE; MACROPHAGE; MAST CELL DEGRANULATION; MONOCYTE; NEUTROPHIL; NONHUMAN; VASCULAR ENDOTHELIUM;

EID: 0032460257     PISSN: 02724391     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2299(199811/12)45:3/4<103::AID-DDR4>3.0.CO;2-W     Document Type: Conference Paper

References (4)

1. Auchampach JA, Jin X, Wan TC, Caughey GH, Linden J. 1997. Canine mast cell adenosine receptors: cloning and expression of the A3 receptors and evidence that degranulation is mediated by the A2B receptor. Mol Pharmacol 52:846-860.
2. Balazovich KJ, Boxer LA. 1990. Extracellular adenosine nucleolides stimulate protein kinase C activity and human neutrophil activation. J Immunol 144:631-637.
3. Carson DA. 1993. New adenosine kinase inhibitors with oral antiinflammatory activity: synthesis and biological evaluation. J Med Chem 36:3424-3430.
4. Cronstein BN. 1995. The antirheumatic agents snlphasalazine and methotrexate share an anti-inflammatory mechanism. Br J Rheumatol 34:30-32.