Studies of regulation of expression of the propionate (prpBCDE) operon provide insights into how Salmonella typhimurium LT2 integrates its 1,2- propanediol and propionate catabolic pathways

Journal of Bacteriology

Volumn 180, Issue 24, 1998, Pages 6511-6518

  Tsang, Allen W ^a   Horswill, Alexander R ^a   Escalante Semerena, Jorge C ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COENZYME A; PROPIONIC ACID; PROPYLENE GLYCOL;

ARTICLE; BACTERIAL METABOLISM; CATABOLISM; ENZYME SYNTHESIS; GENE EXPRESSION REGULATION; NONHUMAN; OPERON; PRIORITY JOURNAL; SALMONELLA TYPHIMURIUM; TRANSCRIPTION REGULATION;

BACTERIA (MICROORGANISMS); NEGIBACTERIA; PROKARYOTA; SALMONELLA TYPHIMURIUM; TYPHIMURIUM;

EID: 0032446552     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/jb.180.24.6511-6518.1998     Document Type: Article

References (37)

1. Anderson, R. P., and J. R. Roth. 1977. Tandem genetic duplications in phage and bacteria. Annu. Rev. Microbiol. 31:473-505.
2. Aoki, H., H. Uchiyama, H. Umetsu, and T. Tabuchi. 1995. Isolation of 2-methylcitrate dehydratase, a new enzyme serving in the methylcitric acid cycle for propionate metabolism, from Yallowia lipolytica. Biosci. Biotechnol. Biochem. 59:1825-1828.
3. Blattner, F. R., G. Plunkett III, C. A. Bloch, N. T. Perna, V. Burland, M. Riley, J. Collado-Vides, J. D. Glasner, C. K. Rode, G. F. Majhew, J. Gregor, N. W. Davis, H. A. Kirkpatrick, M. A. Goeden, D. J. Rose, B. Mau, and Y. Shao. 1997. The complete genome sequence of Escherichia coli K-12. Science 277:1453-1474.
4. Bobik, T. A., Y. Xu, R. M. Jeter, K. E. Otto, and J. R. Roth. 1997. Propanediol utilization genes (pdu) of Salmonella typhimurium: three genes for the propanediol dehydratase. J. Bacteriol. 179:6633-6639.
5. Castilho, B. A., P. Olfson, and M. J. Casadaban. 1984. Plasmid insertion mutagenesis and lac gene fusions with mini-Mu bacteriophage transposons. J. Bacteriol. 158:488-495.
6. Chan, R. K., D. Botstein, T. Watanabe, and V. Ogata. 1972. Specialized transduction of tetracycline resistance by phage P22 in Salmonella typhimurium. II. Properties of a high transducing lysate. Virology 50:883-898.
7. Davis, R. W., D. Botstein, and J. R. Roth. 1980. A manual for genetic engineering: advanced bacterial genetics. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
8. Escalante-Semerena, J. C., and J. R. Roth. 1987. Regulation of cobalamin biosynthetic operons in Salmonella typhimurium. J. Bacteriol. 169:2251-2258.
9. Gerike, U., D. W. Hough, N. J. Russell, M. L. Djall-Smith, and M. J. Danson. 1998. Citrate synthase and 2-methylcitrate synthase: structural, functional and evolutionary relationships. Microbiology 144:929-935.
10. BAD promoter. J. Bacteriol. 177:4121-4130.
11. Hammelman, T. A., G. A. O'Toole, J. R. Trzebiatowski, A. W. Tsang, D. Rank, and J. C. Escalante-Semerena. 1996. Identification of a new prp locus required for propionate catabolism in Salmonella typhimurium LT2. FEMS Microbiol. Lett. 137:233-239.
12. Hong, J.-S., and B. N. Ames. 1971. Localized mutagenesis of any specific small region of the bacterial chromosome. Proc. Natl. Acad. Sci. USA 68: 3158-3162.
13. Horswill, A. R., and J. C. Escalante-Semerena. 1997. Propionate catabolism in Salmonella typhimurium LT2: two divergently transcribed units comprise the prp locus at 8.5 centisomes, prpR encodes a member of the sigma-54 family of activators, and the prpBCDE genes constitute an operon. J. Bacteriol. 179:928-940.
14. Horswill, A. R., and J. C. Escalante-Semerena. The prpE gene of Salmonella typhimurium LT2 encodes propionyl-CoA synthetase. Submitted for publication.
15. Horswill, A. R., T. Grimek, and J. C. Escalante-Semerena. 1998. Unpublished results.
16. Jeter, R. M. 1990. Cobalamin-dependent 1,2-propanediol utilization by Salmonella typhimurium. J. Gen. Microbiol. 136:887-896.
17. Martínez, E., B. Bartolomé, and F. de la Cruz. 1988. pACY184-derived cloning vectors containing the multiple cloning site and lacZα reporter gene of pUC8/9 and pUC18/19 plasmids. Gene 68:159-162.
18. McCleary, W. R., J. B. Stock, and A. J. Ninfa. 1993. Is acetyl phosphate a global signal in Escherichia coli? J. Bacteriol. 175:2793-2798.
19. O'Toole, G. A., M. R. Rondon, and J. C. Escalante-Semerena. 1993. Analysis of mutants of Salmonella typhimurium defective in the synthesis of the nucleotide loop of cobalamin. J. Bacteriol. 175:3317-3326.
20. Palacios, S., and J. C. Escalante-Semerena. 1998. Unpublished results.
21. Rondon, M. R., and J. C. Escalante-Semerena. 1996. In vitro analysis of the interactions between the PocR regulatory protein and the promoter region of the cobalamin biosynthetic (cob) operon of Salmonella typhimurium LT2. J. Bacteriol. 178:2196-2203.
22. Rondon, M. R., and J. C. Escalante-Semerena. 1992. The poc locus is required for 1,2-propanediol-dependent transcription of the cobalamin biosynthetic (cob) and propanediol utilization (pdu) genes of Salmonella typhimurium. J. Bacteriol. 174:2267-2272.
23. Rondon, M. R., J. R. Trzebiatowski, and J. C. Escalante-Semerena. 1997. Biochemistry and molecular genetics of cobalamin biosynthesis. Prog. Nucleic Acid Res. Mol. Biol. 56:347-384.
24. 12): synthesis and biological significance. Annu. Rev. Microbiol. 50:137-181.
25. Schmieger, H. 1971. A method for detection of phage mutants with altered transduction ability. Mol. Gen. Genet. 100:378-381.
26. Schmieger, H., and H. Bakhaus. 1973. The origin of DNA in transducing particles of P22 mutants with increased transduction frequencies (HT-mutants). Mol. Gen. Genet. 120:181-190.
27. Shingler, V. 1996. Signal sensing by sigma 54-dependent regulators: derepression as a control mechanism. Mol. Microbiol. 19:409-416.
28. Simons, R. W., F. Houman, and N. Kleckner. 1987. Improved single and multicopy lac-based cloning vectors for protein and operon fusions. Gene 53:85-96.
29. Tabuchi, T., and N. Serizawa. 1975. A hypothetical cyclic pathway for the metabolism of odd-carbon n-alkanes or propionyl-CoA via seven-carbon tricarboxylic acids in yeasts. Agric. Biol. Chem. 39:1055-1061.
30. Tabuchi, T., H. Umetsu, H. Aoki, and H. Uchiyama. 1995. Characteristics of 2-methylisocitrate dehydratase, isolated from Yallowia lipolytica, in comparison with aconitase. Biosci. Biotechnol. Biochem. 59:2013-2017.
31. Tang, X., Y. Nakata, H.-O. Li, M. Zhang, H. Gao, A. Fujita, O. Sakatsume, T. Ohta, and K. Yokojama. 1994. The optimization of preparations of competent cells for transformation of E. coli. Nucleic Acids Res. 22:2857-2858.
32. Textor, S., V. F. Wendisch, A. A. De Graaf, U. Müller, M. I. Linder, D. Linder, and W. Buckel. 1997. Propionate oxidation in Escherichia coli: evidence for operation of a methylcitrate cycle in bacteria. Arch. Microbiol. 168:428-436.
33. 1-(5-phospho-α-D-ribosyl)-5,6-dimethylbenzimidazole, an intermediate in the synthesis of the nucleotide loop of cobalamin. J. Bacteriol. 176:3568-3575.
34. Tsang, A. W., and J. C. Escalante-Semerena. 1996. cobB function is required for the catabolism of propionate in Salmonella typhimurium LT2. Evidence for the existence of a substitute function for CobB within the 1,2-propanediol utilization (pdu) operon. J. Bacteriol. 178:7016-7019.
35. Tsang, A. W., and J. C. Escalante-Semerena. 1998. CobB, a new member of the SIR2 family of eucaryotic regulatory proteins, is required to compensate for the lack of nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase activity in cobT mutants during cobalamin biosynthesis in Salmonella typhimurium LT2. J. Biol. Chem. 273:31788-31794.
36. Van Dyk, T. K., and R. A. LaRossa. 1987. Involvement of ack-pta operon products in α-ketobutyrate metabolism in Salmonella typhimurium. Mol. Gen. Genet. 207:435-440.
37. Walter, D., M. Ailion, and J. Roth. 1997. Genetic characterization of the pdu operon: use of 1,2-propanediol in Salmonella typhimurium. J. Bacteriol. 179: 1013-1022.