Genomic organization of the murine polysialyltransferase gene ST8SiaIV (PST-1)

Glycobiology

Volumn 8, Issue 12, 1998, Pages 1165-1172

  Eckhardt, Matthias ^a   Gerardy Schahn, Rita ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Genomic structure; Polysialic acid; Polysialyltransferase

Indexed keywords

LUCIFERASE; POLYSIALIC ACID; SIALYLTRANSFERASE;

ARTICLE; CELL INTERACTION; CELL STRAIN 3T3; CHO CELL; EXON; GENETIC ORGANIZATION; INTRON; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; START CODON;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CELL LINE; CLONING, MOLECULAR; EXONS; GENES, REPORTER; INTRONS; MICE; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS); REGULATORY SEQUENCES, NUCLEIC ACID; RNA, MESSENGER; SEQUENCE ANALYSIS, DNA; SIALYLTRANSFERASES; TRANSCRIPTION, GENETIC;

MURINAE; RODENTIA;

EID: 0032445129     PISSN: 09596658     EISSN: None     Source Type: Journal    
DOI: 10.1093/glycob/8.12.1165     Document Type: Article

References (53)

1. Alcaraz, G. and Goridis, C. (1991) Biosynthesis and processing of polysialylated NCAM by AtT-20 cells. Eur. J. Cell Biol., 55, 165-173.
2. Angata, K., Nakayama, J., Fredette, B., Chong, K., Ranscht, B. and Fukuda, M. (1997) Human STX polysialyltransferase forms the embryonic form of the neural cell adhesion molecule. J. Biol. Chem., 272, 7182-7190.
3. Becker, C.G., Artola, A., Gerardy-Schahn, R., Becker, T., Welzl, H. and Schachner, M. (1996) The polysialic acid modification of the neural cell adhesion molecule is involved in spatial learning and hippocampal long-term potentiation. J. Neurosci. Res., 45, 143-152.
4. Breathnach, R. and Chambon, P. (1981) Organization and expression of eucaryotic split genes coding for proteins. Annu. Rev. Biochem., 50, 349-383.
5. Chang, M.L., Eddy, R.L., Shows, T.B. and Lau, J.T.Y. (1995) Three genes that encode human β-galactoside α2,3-sialyltransferases. Structural analysis and chromosomal mapping studies. Glycobiology, 5, 319-326.
6. Cremer, H., Chazal, G., Goridis, C. and Represa, A. (1997) NCAM is essential for axonal growth and fasciculation in the hippocampus. Mol. Cell. Neurosci., 8, 323-335.
7. Datta, A.K. and Paulson, J.C. (1995) The sialyltransferase "sialylmotif" participates in binding the donor substrate CMP-NeuAc. J. Biol. Chem., 270, 1497-1500.
8. Doherty, P., Cohen, J. and Walsh, F.S. (1990) Neurite outgrowth in response to transfected N-CAM changes during development and is modulated by polysialic acid. Neuron, 5, 209-219.
9. Drickamer, K. (1993) A conserved disulphide bond in sialyltransferases. Glycobiology, 3, 2-3.
10. Eckhardt, M. (1995) Posttranslationale Modifikationen des Neuralen Zelladhäsionsmoleküls NCAM. PhD thesis, Universität Hannover.
11. Eckhardt, M., Mühlenhoff, M., Bethe, A., Koopman, J., Frosch, M. and Gerardy-Schahn, R. (1995) Molecular characterization of eukaryotic polysialyltransferase-1. Nature, 373, 715-718.
12. Eckhardt, M., Mühlenhoff, M., Bethe, A. and Gerardy-Schahn, R. (1996) Expression cloning of the Golgi CMP-sialic acid transporter. Proc. Natl. Acad. Sci. USA, 93, 7572-7576.
13. Faisst, S. and Meyer, S. (1992) Compilation of vertebrate-encoded transcription factors. Nucleic Acids Res., 20, 3-26.
14. Frohman, M.A. (1993) Rapid amplification of complementary DNA ends for generation of full-length complementary DNAs: thermal RACE. Methods Enzymol., 218, 340-356.
15. Geng, Y. and Johnson, L.F. (1993) Lack of an initiator element is responsible for multiple transcriptional initiation sites of the TATA-less mouse thymidylate synthase promoter. Mol. Cell. Biol., 13, 4894-4903.
16. Geremia, R.A., Harduin-Lepers, A. and Delannoy, P. (1997) Identification of two novel conserved amino acid residues in eukaryotic sialyltransferases: implications for their mechanism of action. Glycobiology, 7, v-vii.
17. Haun, R.S., Moss, J. and Vaughan, M. (1993) Characterization of the human ADP-ribosylation factor 3 promoter. Transcriptional regulation of a TATA-less promoter. J. Biol. Chem., 268, 8793-8800.
18. Kiss, J.Z. and Rougon, G. (1997) Cell biology of polysialic acid. Curr. Opin. Neurobiol., 7, 640-646.
19. Kitagawa, H., Mattei, M.-G. and Paulson, J.C. (1996) Genomic organization and chromosomal mapping of the Galβ1,3GalNAc/Galβ1,4GlcNAcα2,3-sialyltransferase. J. Biol. Chem., 271, 931-938.
20. Kojima, N., Yoshida, Y., Kurosawa, N., Young-Choon, L. and Tsuji, S. (1995a) Enzymatic activity of a developmentally regulated member of the sialyltransferase family (STX): evidence for α2,8-sialyltransferase activity toward N-linked oligosaccharides. FEBS Lett., 360, 1-4.
21. Kojima, N., Yoshida, Y. and Tsuji, S. (1995b) A developmentally regulated member of the sialyltransferase family (ST8SiaII, STX) is a polysialic acid synthase. FEBS Lett., 373, 119-122.
22. Kojima, N., Kono, M., Yoshida, Y., Tachida, Y., Nakafuku, M. and Tsuji, S. (1996) Biosynthesis and expression of polysialic acid on the neural cell adhesion molecule is predominantly directed by ST8Sia II/STX during in vitro neuronal differentiation. J. Biol. Chem., 271, 22058-22062.
23. Kojima, N., Tachida, Y. and Tsuji, S. (1997) Two polysialic acid synthases, mouse ST8Sia II and IV, synthesize different degrees of polysialic acids on different substrate glycoproteins in mouse neuroblastoma Neuro2a cells. J. Biochem., 122, 1265-1273.
24. Kurosawa, N., Inoue, M., Yoshida, Y. and Tsuji, S. (1996) Molecular cloning and genomic analysis of mouse Galβ1,3GalNAc-specific GalNAc α2,6-sialyltransferase. J. Biol. Chem., 271, 15109-15116.
25. Kurosawa, N., Yoshida, Y., Kojima, N. and Tsuji, S. (1997) Polysialic acid synthase (ST8SiaII/STX) mRNA expression in the developing mouse central nervous system. J. Neurochem., 69, 494-503.
26. Livingston, B.D. and Paulson, J.C. (1993) Polymerase chain reaction cloning of a developmentally regulated member of the sialyltransferase gene family. J. Biol. Chem., 268, 11504-11507.
27. Mount, S.M. (1982) A catalogue of splice junction sequences. Nucleic Acids Res., 10, 459-472.
28. Mühlenhoff, M. (1996) Molekulare Charakterisierung der eukaryontischen Polysialyltransferase. PhD thesis, Universität Hannover.
29. Mühlenhoff, M., Eckhardt, M., Bethe, A., Frosch, M. and Gerardy-Schahn, R. (1996a) Autocatalytic polysialylation of polysialyltransferase-1. EMBO J., 15, 6943-6950.
30. Mühlenhoff, M., Eckhardt, M., Bethe, A., Frosch, M. and Gerardy-Schahn, R. (1996b) Polysialylation of NCAM by a single enzyme. Curr. Biol., 6, 1188-1191.
31. Mühlenhoff, M., Eckhardt, M. and Gerardy-Schahn, R. (1997) Molecular characterisation of the polysialyltransferases: a comparative study of ST8SiaII and ST8SiaIV. Glycoconjugate J., 14, S129.
32. Muller, D., Wang, C., Skibo, G., Toni, G., Cremer, H., Calaora, V., Rougon, G. and Kiss, J.Z. (1996) PSA-NCAM is required for activity-induced synaptic plasticity. Neuron, 17, 413-422.
33. Nakayama, J and Fukuda, M. (1996) A human polysialyltransferase directs in vitro synthesis of polysialic acid. J. Biol. Chem., 271, 1829-1832.
34. Nakayama, J., Fukuda, M.N., Fredette, B., Ranscht, B. and Fukuda, M. (1995) Expression cloning of a human polysialyltransferase that forms the polysialylated neural cell adhesion molecule present in embryonic brain. Proc. Natl. Acad. Sci. USA, 92, 7031-7035.
35. Phillips, G.R., Krushel, L.A. and Crossin, K.L. (1997) Developmental expression of two rat sialyltransferases that modify the neural cell adhesion molecule, N-CAM. Dev. Brain Res., 102, 143-155.
36. 2+ and protein kinase C. J. Cell Biol., 132, 969-983.
37. Rutishauser, U. (1996) Polysialic acid and the regulation of cell interactions. Curr. Opin. Cell Biol., 8, 679-684.
38. Saffer, J.D., Jackson, S.P. and Annarella, M.B. (1991) Developmental expression of Sp1 in the mouse. Mol. Cell. Biol., 11, 2189-2199.
39. Saiki, R.K., Gelfand, D.H., Stoffel, S., Scharf, S.J., Higuchi, R., Horn, G.T., Mullis, K.B. and Erlich, H.A. (1988) Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. Science, 239, 487-491.
40. Sambrook, J., Fritsch, E.F. and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual. Gold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
41. Sanger, E., Nicklen, S. and Coulson, A.R. (1977) DNA sequencing with chain terminating inhibitors. Proc. Natl. Acad. Sci. USA, 74, 5463-5467.
42. Scheidegger, E.P., Sternberg, L.R., Roth, J. and Lowe, J.B. (1995) A human STX cDNA confers polysialic acid expression on mammalian cells. J. Biol. Chem., 270, 22685-22688.
43. Seki, T. and Arai, Y. (1993) Distribution and possible roles of the highly polysialylated neural cell adhesion molecule (NCAM-H) in the developing and adult central nervous system. Neurosci. Res., 17, 265-290.
44. Smith, C.L. and Hager, G.L. (1997) Transcriptional regulation of mammalian genes in vivo. J. Biol. Chem., 272, 27493-27496.
45. Svensson, E.C., Soreghan, B. and Paulson, J.C. (1990) Organization of the β-galactoside α2,6-sialyltransferase gene: evidence for the transcriptional regulation of terminal glycosylation. J. Biol. Chem., 265, 20863-20868.
46. Tsuji, S. (1996) Molecular cloning and functional analysis of sialyltransferases. J. Biochem., 120, 1-13.
47. Wang, X.C., O'Hanlon, T.P., Young, R.F. and Lau, J.T.Y. (1990) Rat β-galactoside α2,6-sialyltransferase genomic organization: alternate promoters direct the synthesis of liver and kidney transcripts. Glycobiology, 1, 25-31.
48. Wasylyk, C., Wasylyk, B., Heidecker, G., Huleihel, M. and Rapp, U.R. (1989) Expression of raf oncogenes activates the PEA1 transcription factors motif. Mol. Cell. Biol., 9, 2247-2250.
49. Williams, T. and Tjian, R. (1991) Analysis of the DNA-binding and activation properties of the human transcription factor AP-2. Genes Dev., 5, 670-682.
50. Wood, G.K., Liang, J.J., Flores, G., Ahmad, S., Quirion, R. and Srivastava, L.K. (1997) Cloning and in situ hybridization analysis of the expression of polysialyltransferase mRNA in the developing and adult rat brain. Mol. Brain Res., 51, 69-81.
51. Yoshida, Y., Kojima, N. and Tsuji, S. (1995) Molecular cloning and characterization of a third type of N-glycan α2,8-sialyltransferase from mouse lung. J. Biochem., 118, 658-664.
52. Yoshida, Y., Kurosawa, N., Kanematsu, T., Taguchi, A., Arita, M., Kojima, N. and Tsuji, S. (1996a) Unique genomic structure and expression of the mouse α2,8-sialyltransferase (ST8SiaIII) gene. Glycobiology, 6, 573-580.
53. Yoshida, Y., Kurosawa, N., Kanematsu, T., Kojima, N. and Tsuji, S. (1996b) Genomic structure and promoter activity of the mouse polysialic acid synthase gene (mST8SiaII), J. Biol. Chem., 271, 30167-30173.