Effects of barnidipine hydrochloride, a calcium channel blocker, on renal microcirculation in rats: A pilot study

Current Therapeutic Research - Clinical and Experimental

Volumn 59, Issue 12, 1998, Pages 826-834

  Kimura, Kenjiro ^a   Suzuki, Naoe ^a   Mise, Naobumi ^a   Oba, Shigeyoshi ^a   Miyashita, Kazuhisa ^a   Tojo, Akihiro ^a   Hirata, Yasunobu ^a   Goto, Atsuo ^a   Omata, Masao ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Barnidipine hydrochloride; Hydronephrotic kidney model; Renal microcirculation

Indexed keywords

CALCIUM CHANNEL BLOCKING AGENT; MEPIRODIPINE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CALCIUM TRANSPORT; FEMALE; GLOMERULUS FILTRATION; HYDRONEPHROSIS; INTRAVENOUS DRUG ADMINISTRATION; KIDNEY BLOOD FLOW; KIDNEY CIRCULATION; MICROCIRCULATION; NONHUMAN; PRIORITY JOURNAL; RAT; SYSTOLIC BLOOD PRESSURE; VASODILATATION;

EID: 0032442844     PISSN: 0011393X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0011-393X(98)85046-7     Document Type: Article

References (18)

1. Dworkin LD, Feiner HD, Parker M, Tolbert E. Effects of nifedipine and enalapril on glomerular structure and function in uninephrectomized SHR. Kidney Int. 1991;39:1112-1117.
2. Brunner FP, Thiel G, Hermle M, et al. Long-term enalapril and verapamil in rats with reduced renal mass. Kidney Int. 1989;36:969-977.
3. Teramura T, Watanabe T, Higuchi S, Hashimoto K. Pharmacokinetics of barnidipine hydrochloride, a new dihydropyridine calcium channel blocker, in the rat, dog and human. Xenobiotica. 1995;25:1237-1246.
4. Saitoh M, Kasai C, Ishikawa J, et al. Effect of barnidipine on blood flow to major organs and renal function in anaesthetized dogs and spontaneously hypertensive rats. Clin Exp Pharmacol Physiol Suppl. 1995;(Suppl 1):S339-S340.
5. Kaizu K, Ling QY, Uriu K, et al. Acute effect of calcium blocker on renal hemodynamics in diabetic spontaneously hypertensive rat. J Diabet Complications. 1995;9:301-303.
6. Steinhausen M, Snoei H, Parekh N, et al. Hydronephrosis: A new method to visualize vas afferens, efferens, and glomerular network. Kidney Int. 1983;23:794-806.
7. Kimura K, Tojo A, Hirata Y, et al. Effects of a calcium antagonist and an angiotensin II receptor antagonist on rat renal arterioles. Blood Press Suppl. 1994;5:71-74.
8. Kimura K, Suzuki N, Ohba S, et al. Effects of amlodipine, a calcium channel blocker, on rat renal arterioles. Curr Ther Res. 1997;58:375-380.
9. Kimura K, Inokuchi S, Sugaya T, et al. Location and action of angiotensin II type 1 receptor in the renal microcirculation. Kidney Int. 1997;52(Suppl 63):S201-S204.
10. Steinhausen M, Holz FG. Autoregulation of glomerular blood flow during converting-enzyme inhibition by captopril. Biomed Biochim Acta. 1987;46:1005-1009.
11. Steinhausen M, Weis S, Fleming J, et al. Responses of in vivo renal microvessels to dopamine. Kidney Int. 1986;30:361-370.
12. Steinhausen M, Kucherer H, Parekh N, et al. Angiotensin II control of the renal microcirculation: Effect of blockade by saralasin. Kidney Int. 1986;30:56-61.
13. Holz FG, Steinhausen M. Renovascular effects of adenosine receptor agonists. Renal Physiol. 1987;10:272-282.
14. Steinhausen M, Fleming JT, Holz FG, Parekh N. Nitrendipine and the pressure-dependent vasodilation of vessels in the hydronephrotic kidney. J Cardiovasc Pharmacol. 1987;9(Suppl 1):S39-S43.
15. Myers BD, Deen WM, Robertson CR, Brenner BM. Dynamics of glomerular ultrafiltration in the rat. VIII. Effects of hematocrit. Circ Res. 1975;36:425-435.
16. Hostetter TH, Olson JL, Rennke HG, et al. Hyperfiltration in remnant nephrons: A potentially adverse response to renal ablation. Am J Physiol. 1981;241:F85-F93.
17. Brenner BM, Meyer TW, Hostetter TH. Dietary protein intake and the progressive nature of kidney disease: The role of hemodynamically mediated glomerular injury in the pathogenesis of progressive glomerular sclerosis in aging, renal ablation, and intrinsic renal disease. NEJM. 1982;307:652-659.
18. Dworkin LD, Hostetter TH, Rennke HG, Brenner BM. Hemodynamic basis for glomerular injury in rats with desoxycorticosterone-salt hypertension. J Clin Invest. 1984; 73:1448-1461.