Protection against dynorphin-(1-8) hydrolysis in membrane preparations by the combination of amastatin, captopril and phosphoramidon

Journal of Pharmacology and Experimental Therapeutics

Volumn 286, Issue 2, 1998, Pages 863-869

  Hiranuma, Toyokazu ^a   Kitamura, Ken ^a   Taniguchi, Takao ^a   Kanai, Masayuki ^a   Arai, Yoshiharu ^a   Iwao, Kayoko ^a   Oka, Tetsuo ^a  

^a TOKAI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMASTATIN; AMINOPEPTIDASE; CAPTOPRIL; DELTA OPIATE RECEPTOR; DEXTRO PHENYLALANYLCYSTEINYLTYROSYL DEXTRO TRYPTOPHYLORNITHYLTHREONYLPENICILLAMINYLTHREONINAMIDE 2,7 DISULFIDE; DIPEPTIDYL CARBOXYPEPTIDASE; DYNORPHIN[1-8]; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; ENKEPHALIN[2,5 DEXTRO PENICILLAMINE]; KAPPA OPIATE RECEPTOR; KETAZOCINE; MEMBRANE METALLOENDOPEPTIDASE; MORPHINE; MU OPIATE RECEPTOR; N,N DIALLYLTYROSYL 2 METHYLALANYL 2 METHYLALANYLPHENYLALANYLLEUCINE; NORBINALTORPHIMINE; PHOSPHORAMIDON;

ANIMAL TISSUE; ARTICLE; BRAIN MEMBRANE; CONTROLLED STUDY; CORPUS STRIATUM; DISSOCIATION CONSTANT; DRUG POTENCY; ENZYME ACTIVITY; GUINEA PIG; ILEUM; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTECTION; PROTEIN DEGRADATION; RECEPTOR DENSITY; SYNAPTIC MEMBRANE; VAS DEFERENS;

ANIMALS; ANTI-BACTERIAL AGENTS; BIOTRANSFORMATION; CAPTOPRIL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DYNORPHINS; ELECTROCHEMISTRY; GLYCOPEPTIDES; GUINEA PIGS; HYDROLYSIS; HYPOTHALAMIC HORMONES; KINETICS; MALE; MEMBRANES; MICE; MICE, INBRED ICR; PEPTIDE FRAGMENTS; PEPTIDES; PROTEASE INHIBITORS; RECEPTORS, OPIOID, DELTA; RECEPTORS, OPIOID, KAPPA;

EID: 0032437267     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Aoki K, Kajiwara M and Oka T (1984) The role of bestatin-sensitive aminopeptidase, angiotensin converting enzyme and thiorphan-sensitive "enkephalinase" in the potency of enkephalins in the guinea-pig ileum. Jpn J Pharmacol 36:59-65.
2. 5]-enkephalin by bestatin-sensitive aminopeptidase, captopril-sensitive peptidyl dipeptidase A and thiorphan-sensitive endopeptidase-24.11 in mouse vas deferens. Jpn J Pharmacol 40:297-302.
3. 1-9 are ligands for the κ-subtype of opiate receptor. Nature 299:79-81.
4. Cotton R, Giles MG, Miller L, Shaw JS and Timms D (1984) ICI 174864: A highly selective antagonist for the opioid δ-receptor. Eur J Pharmacol 97:331-332.
5. 5]-enkephalin in rat vas deferens. Jpn J Pharmacol 42:43-49.
6. 3H]dopa in various regions of the brain. J Neurochem 13:655-669.
7. Gulya K, Pelton JT, Hruby VJ and Yamamura HI (1986) Cyclic somatostatin octapeptide analogues with high affinity and selectivity toward mu opioid receptors. Life Sci 38:2221-2229.
8. 61-64 possessing selective agonist activity at μ-opiate receptors. Eur J Pharmacol 70:531-540.
9. 8 (Met-enk-RGL) hydrolysis in membrane preparations by the combination of amastatin, captopril and phosphoramidon. J Pharmacol Exp Ther 281:769-774.
10. 7 and other opioid peptides. Naunyn-Schmiedeberg Arch Pharmacol, 357:276-282.
11. 5]-enkephalin hydrolysis in ileal and striatal preparations of guinea-pig: almost complete protection of degradation by the combination of amastatin, captopril and thiorphan. Jpn J Pharmacol 41:437-446.
12. Kakidani H, Furutani Y, Takahashi H, Noda M, Morimoto Y, Hirose T, Asai M, Inayama S, Nakanishi S and Numa S (1982) Cloning and sequence analysis of cDNA for porcine β-neo-endorphin/dynorphin precursor. Nature 298:245-249.
13. 2OH is a selective ligand for the μ-opiate binding site. Br J Pharmacol 73:299P.
14. Kosterlitz HW and Watt AJ (1968) Kinetic parameters of narcotic agonists and antagonists, with particular reference to N-allylnoroxymorphone (naloxone). Br J Pharmacol 33:266-276.
15. Lord JAH, Waterfield AA, Hughes J and Kosterlitz HW (1977) Endogenous opioid peptides: multiple agonists and receptors. Nature 267:495-499.
16. Lowry OH, Rosebrough NJ, Farr AL and Randall RJ (1951) Protein measurement with the Folin phenol reagent. J Biol Chem 193:265-275.
17. Matsas R, Fulcher IS, Kenny AJ and Turner AJ (1983) Substance P and [Leu]enkephalin are hydrolyzed by an enzyme in pig caudate synaptic membranes that is identical with the endopeptidase of kidney microvilli. Proc Natl Acad Sci USA 80:3111-3115.
18. Matsas R, Stephenson SL, Hryszko J, Kenny AJ and Turner AJ (1985) The metabolism of neuropeptides. Biochem J 231:445-449.
19. McKnight AT, Corbett AD and Kosterlitz HW (1983) Increase in potencies of opioid peptides after peptidase inhibition. Eur J Pharmacol 86:393-402.
20. Morley JS (1980) Structure-activity relationships of enkephalin-like peptides. Annu Rev Pharmacol Toxicol 20:81-110.
21. Mosberg HI, Hurst R, Hruby VJ, Gee K, Yamamura HI, Galligan JJ and Burks TF (1983) Bis-penicillamine enkephalins possess highly improved specificity toward 5 opioid receptors. Proc Natl Acad Sci USA 80:5871-5874.
22. Numata H, Hiranuma T and Oka T (1988) Inactivation of dynorphin-(1-8) in isolated preparations by three peptidases. Jpn. J Pharmacol 47:417-423.
23. Oka T, Liu X-F, Kajita T, Ohgiya N, Ghoda K, Taniguchi T, Arai Y and Matsumiya T (1992) Effects of the subcutaneous administration of enkephalins on tail-flick response and righting reflex of developing rats. Dev Brain Res 69:271-276.
24. Oka T and Negishi K (1982) Evidence that endogenous 6-(Arg or Lys)-opioid peptides can interact with κ-receptors as agonists. Life Sci 31:1707-1710.
25. Oka T, Negishi K, Suda M, Sawa A, Fujino M and Wakimasu M (1982) Evidence that dynorphin-(1-13) acts as an agonist on opioid κ-receptors. Eur J Pharmacol 77:137-141.
26. Pelton JT, Kazmierski W, Gulya K, Yamamura HI and Hruby VJ (1986) Design and synthesis of conformationally constrained somatostatin analogues with high potency and specificity for μ opioid receptors. J Med Chem 29:2370-2375.
27. Portoghese PS, Nagase H, Lipkowski AW, Larson DL and Takemori AE (1988) Binaltorphimine-related bivalent ligands and their κ opioid receptor antagonist selectivity. J Med Chem 31:836-841.
28. Rubin B, Laffan RJ, Kotler DG, O'Keefe EH, Demaio DA and Goldberg ME (1978) SQ 14,225 (D-3-mercapto-2-methyl proparoyl-L-proline), a novel orally active inhibitor of angiotensin I converting enzymes. J Pharmacol Exp Ther 204:271-280.