Mutations at position 1122 in the catalytic domain of the mouse ras-specific guanine nucleotide exchange factor CDC25(Mm) originate both loss-of-function and gain-of-function proteins

FEBS Letters

Volumn 440, Issue 3, 1998, Pages 291-296

  Carrera, Vittorio ^a   Moroni, Andrea ^a   Martegani, Enzo ^a   Volponi, Celina ^b   Cool, Robbert H ^b   Alberghina, Lilia ^a   Vanoni, Marco ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY   (Germany)

Author keywords

BIAcore; fos Luciferase; Guanine nucleotide exchange factor; Oncogene; Site directed mutagenesis; Yeast

Indexed keywords

GUANINE NUCLEOTIDE EXCHANGE FACTOR; LUCIFERASE; MUTANT PROTEIN;

AMINO ACID SUBSTITUTION; ARTICLE; MUTATION; NONHUMAN; NUCLEOTIDE SEQUENCE; ONCOGENE; PRIORITY JOURNAL; PROTEIN DOMAIN; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS; YEAST;

3T3 CELLS; ANIMALS; CATALYTIC DOMAIN; CELL CYCLE PROTEINS; CHO CELLS; CRICETINAE; GENES, FOS; GUANINE NUCLEOTIDES; MICE; MUTAGENESIS, SITE-DIRECTED; PHOSPHOPROTEIN PHOSPHATASE; RAS PROTEINS; RAS-GRF1; SACCHAROMYCES CEREVISIAE; TRANSFECTION;

MAMMALIA; SACCHAROMYCES CEREVISIAE;

EID: 0032436012     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(98)01481-1     Document Type: Article

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