-
1
-
-
0024327043
-
Molecular mechanism of bone resorption by the osteoclast
-
For review see
-
For review see: Baron R. Molecular mechanism of bone resorption by the osteoclast. Anat. Rec. 224:1989;317-324.
-
(1989)
Anat. Rec.
, vol.224
, pp. 317-324
-
-
Baron, R.1
-
3
-
-
0019156408
-
Inhibition of bone resorption in culture by inhibitors of thiol proteinases
-
Delaisse J. M., Eeckhout Y., Vaes G. Inhibition of bone resorption in culture by inhibitors of thiol proteinases. Biochem. J. 192:1980;365-368.
-
(1980)
Biochem. J.
, vol.192
, pp. 365-368
-
-
Delaisse, J.M.1
Eeckhout, Y.2
Vaes, G.3
-
4
-
-
0026587183
-
Human cystatin C, a cysteine proteinase inhibitor, inhibits bone resorption in vitro stimulated by parathyroid hormone and parathyroid hormone-related peptide of malignancy
-
Lerner U. H., Grubb A. Human cystatin C, a cysteine proteinase inhibitor, inhibits bone resorption in vitro stimulated by parathyroid hormone and parathyroid hormone-related peptide of malignancy. J. Bone Miner. Res. 7:1992;433-440.
-
(1992)
J. Bone Miner. Res.
, vol.7
, pp. 433-440
-
-
Lerner, U.H.1
Grubb, A.2
-
5
-
-
0023607260
-
The effects of inhibitors of cysteine-proteinases and collagenase on the resorptive activity of isolated osteoclasts
-
Delaisse J. M., Boyde A., Maconnachie E., Ali N. N., Sear C. H. J., Eeckhout Y., Vaes G., Jones S. J. The effects of inhibitors of cysteine-proteinases and collagenase on the resorptive activity of isolated osteoclasts. Bone. 8:1987;305-313.
-
(1987)
Bone
, vol.8
, pp. 305-313
-
-
Delaisse, J.M.1
Boyde, A.2
MacOnnachie, E.3
Ali, N.N.4
Sear, C.H.J.5
Eeckhout, Y.6
Vaes, G.7
Jones, S.J.8
-
6
-
-
0027994398
-
Inhibition of bone resorption by selective inactivators of cysteine proteinases
-
Hill P. A., Buttle D. J., Jones S. J., Boyde A., Murata M., Reynolds J. J., Meikle M. C. Inhibition of bone resorption by selective inactivators of cysteine proteinases. J. Cell. Biochem. 56:1994;118-130.
-
(1994)
J. Cell. Biochem.
, vol.56
, pp. 118-130
-
-
Hill, P.A.1
Buttle, D.J.2
Jones, S.J.3
Boyde, A.4
Murata, M.5
Reynolds, J.J.6
Meikle, M.C.7
-
7
-
-
0030984531
-
Cathepsin K antisense oligodeoxynucleotide inhibits osteoclastic bone resorption
-
Inui T., Ishibashi O., Inaoka T., Origane Y., Kumegawa M., Kokubo T., Yamamura T. Cathepsin K antisense oligodeoxynucleotide inhibits osteoclastic bone resorption. J. Biol. Chem. 272:1997;8109-8112.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 8109-8112
-
-
Inui, T.1
Ishibashi, O.2
Inaoka, T.3
Origane, Y.4
Kumegawa, M.5
Kokubo, T.6
Yamamura, T.7
-
8
-
-
15844422855
-
Cathepsin K, but not cathepsins B, L, or S, is abundantly expressed in human osteoclasts
-
Drake F. H., Dodds R. A., James I. E., Conner J. R., Debouck C., Richardson S., Lee-Rykaczewdki E., Coleman L., Rieman D., Barthlow R., Hastings G., Gowen M. Cathepsin K, but not cathepsins B, L, or S, is abundantly expressed in human osteoclasts. J. Biol. Chem. 271:1996;12511-12516.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 12511-12516
-
-
Drake, F.H.1
Dodds, R.A.2
James, I.E.3
Conner, J.R.4
Debouck, C.5
Richardson, S.6
Lee-Rykaczewdki, E.7
Coleman, L.8
Rieman, D.9
Barthlow, R.10
Hastings, G.11
Gowen, M.12
-
9
-
-
15844397808
-
Proteolytic activity of human osteoclast cathepsin K: Expression, purification activation and substrate identification
-
Bossard M. J., Tomaszek T. A., Thompson S. K., Amegadzie B. Y., Hannings C. R., Jones C., Kurdyla J. T., McNulty D. E., Drake F. H., Gowen M., Levy M. A. Proteolytic activity of human osteoclast cathepsin K: Expression, purification activation and substrate identification. J. Biol. Chem. 271:1996;12517-12524.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 12517-12524
-
-
Bossard, M.J.1
Tomaszek, T.A.2
Thompson, S.K.3
Amegadzie, B.Y.4
Hannings, C.R.5
Jones, C.6
Kurdyla, J.T.7
McNulty, D.E.8
Drake, F.H.9
Gowen, M.10
Levy, M.A.11
-
10
-
-
0028831635
-
Molecular cloning of human cDNA for cathepsin K: Novel cysteine proteinase predominantly expressed in bone
-
Inaoka T., Bilbe G., Ishibashi O., Tezuka K., Kumegawa M., Kokubo T. Molecular cloning of human cDNA for cathepsin K: Novel cysteine proteinase predominantly expressed in bone. Biochem. Biophys. Res. Commun. 206:1995;89-96.
-
(1995)
Biochem. Biophys. Res. Commun.
, vol.206
, pp. 89-96
-
-
Inaoka, T.1
Bilbe, G.2
Ishibashi, O.3
Tezuka, K.4
Kumegawa, M.5
Kokubo, T.6
-
11
-
-
0029310512
-
Human cathepsin O2, a novel cysteine protease highly expressed in osteoclastmas and ovary: Molecular cloning sequencing and tissue distribution
-
Bromme D., Okamoto K. Human cathepsin O2, a novel cysteine protease highly expressed in osteoclastmas and ovary: Molecular cloning sequencing and tissue distribution. Biol. Chem. Hoppe-Seyler. 376:1995;379-384.
-
(1995)
Biol. Chem. Hoppe-Seyler
, vol.376
, pp. 379-384
-
-
Bromme, D.1
Okamoto, K.2
-
12
-
-
0030026637
-
Human cathepsin O2, a matrix protein-degrading cysteine protease expressed in osteoclasts
-
Bromme D., Okamoto K., Wang B. B., Biroc S. Human cathepsin O2, a matrix protein-degrading cysteine protease expressed in osteoclasts. J. Biol. Chem. 271:1995;2126-2132.
-
(1995)
J. Biol. Chem.
, vol.271
, pp. 2126-2132
-
-
Bromme, D.1
Okamoto, K.2
Wang, B.B.3
Biroc, S.4
-
13
-
-
0028835637
-
Molecular cloning of human cathepsin O, a novel endoproteinase and homologue of rabbit OC2
-
Shi G.-P., Chapman H. A., Bhairi S. M., Deleeuw C., Reddy V. Y., Weiss S. J. Molecular cloning of human cathepsin O, a novel endoproteinase and homologue of rabbit OC2. FEBS Lett. 357:1995;129-134.
-
(1995)
FEBS Lett.
, vol.357
, pp. 129-134
-
-
Shi, G.-P.1
Chapman, H.A.2
Bhairi, S.M.3
Deleeuw, C.4
Reddy, V.Y.5
Weiss, S.J.6
-
14
-
-
0028123480
-
Molecular cloning of a possible cysteine proteinase predominantly expressed in osteoclasts
-
Tezuka K., Tezuka Y., Maejima A., Sato T., Nemoto K., Kamioka H., Hakeda Y., Kumegawa M. Molecular cloning of a possible cysteine proteinase predominantly expressed in osteoclasts. J. Biol. Chem. 269:1994;1106-1109.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 1106-1109
-
-
Tezuka, K.1
Tezuka, Y.2
Maejima, A.3
Sato, T.4
Nemoto, K.5
Kamioka, H.6
Hakeda, Y.7
Kumegawa, M.8
-
15
-
-
0029809357
-
Pycnodysostosis, a lysosomal disease caused by cathepsin K deficiency
-
Gelb B. D., Shi G.-P., Chapman H. A., Desnick R. J. Pycnodysostosis, a lysosomal disease caused by cathepsin K deficiency. Science. 273:1996;1236-1238.
-
(1996)
Science
, vol.273
, pp. 1236-1238
-
-
Gelb, B.D.1
Shi, G.-P.2
Chapman, H.A.3
Desnick, R.J.4
-
16
-
-
0031014610
-
Crystal structure of human osteoclast cathepsin K complex with E-64
-
Zhao B., Janson C. A., Amegadzie B. Y., D'Alessio K., Griffin C., Hanning C. R., Jones C., Kurdyla J., McQueney M., Qiu X., Smith W. W., Abdel-Meguid S. S. Crystal structure of human osteoclast cathepsin K complex with E-64. Nature Struct. Biol. 4:1997;109-111.
-
(1997)
Nature Struct. Biol.
, vol.4
, pp. 109-111
-
-
Zhao, B.1
Janson, C.A.2
Amegadzie, B.Y.3
D'Alessio, K.4
Griffin, C.5
Hanning, C.R.6
Jones, C.7
Kurdyla, J.8
McQueney, M.9
Qiu, X.10
Smith, W.W.11
Abdel-Meguid, S.S.12
-
17
-
-
0031030808
-
Crystal structure of human cathepsin K complexed with a potent inhibitor
-
McGrath M. E., Klaus J. L., Barnes M. G., Bromme D. Crystal structure of human cathepsin K complexed with a potent inhibitor. Nature Struct. Biol. 4:1997;105-109.
-
(1997)
Nature Struct. Biol.
, vol.4
, pp. 105-109
-
-
McGrath, M.E.1
Klaus, J.L.2
Barnes, M.G.3
Bromme, D.4
-
18
-
-
17944403442
-
Autocatalytic activation of human cathepsin K
-
McQueney M. S., Amegadzie B. Y., D'Alessio K. D., Hanning C. R., McLaughlin M. M., McNulty D., Carr S. A., Ijames C., Kurdyla J., Jones C. S. Autocatalytic activation of human cathepsin K. J. Biol. Chem. 272:1997;13955-13960.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 13955-13960
-
-
McQueney, M.S.1
Amegadzie, B.Y.2
D'Alessio, K.D.3
Hanning, C.R.4
McLaughlin, M.M.5
McNulty, D.6
Carr, S.A.7
Ijames, C.8
Kurdyla, J.9
Jones, C.S.10
-
19
-
-
0030716360
-
Structure and design of potent and selective cathepsin K inhibitors
-
Yamashita D. S., Smith W. W., Zhao B., Janson C. A., Tomaszek T. A., Bossard M. J., Levy M. A., Oh H.-J., Carr T. J., Thompson S. K., Ijames C. F., Carr S. A., McQueney M., D'Alessio K. J., Amegadzie B. Y., Hanning C. R., Abdel-Meguid S., DesJarlais R. L., Gleason J. G., Veber D. F. Structure and design of potent and selective cathepsin K inhibitors. J. Am. Chem. Soc. 119:1997;11351-11352.
-
(1997)
J. Am. Chem. Soc.
, vol.119
, pp. 11351-11352
-
-
Yamashita, D.S.1
Smith, W.W.2
Zhao, B.3
Janson, C.A.4
Tomaszek, T.A.5
Bossard, M.J.6
Levy, M.A.7
Oh, H.-J.8
Carr, T.J.9
Thompson, S.K.10
Ijames, C.F.11
Carr, S.A.12
McQueney, M.13
D'Alessio, K.J.14
Amegadzie, B.Y.15
Hanning, C.R.16
Abdel-Meguid, S.17
Desjarlais, R.L.18
Gleason, J.G.19
Veber, D.F.20
more..
-
20
-
-
0000263910
-
Design of potent and selective human cathepsin K inhibitors that span the active site
-
Thompson S. K., Halbert S. M., Bossard M. J., Tomaszek T. A., Levy M. A., Zhao B., Smith W. W., Abdel-Meguid S. S., Janson C. A., D'Alessio K. J., McQueney M. S., Amegadzie B. Y., Hanning C. R., DesJarlais R. L., Briand J., Sarkar S. K., Huddleston M. J., Ijames C. F., Carr S. A., Garnes K. T., Shu A., Heys J. R., Bradbeer J., Zembryki D., Lee-Rykaczewski L., James I. E., Lark M. W., Drake F. H., Gowen M., Gleason J. G., Veber D. F. Design of potent and selective human cathepsin K inhibitors that span the active site. Proc. Natl. Acad. Sci. USA. 94:1997;14249-14254.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 14249-14254
-
-
Thompson, S.K.1
Halbert, S.M.2
Bossard, M.J.3
Tomaszek, T.A.4
Levy, M.A.5
Zhao, B.6
Smith, W.W.7
Abdel-Meguid, S.S.8
Janson, C.A.9
D'Alessio, K.J.10
McQueney, M.S.11
Amegadzie, B.Y.12
Hanning, C.R.13
Desjarlais, R.L.14
Briand, J.15
Sarkar, S.K.16
Huddleston, M.J.17
Ijames, C.F.18
Carr, S.A.19
Garnes, K.T.20
Shu, A.21
Heys, J.R.22
Bradbeer, J.23
Zembryki, D.24
Lee-Rykaczewski, L.25
James, I.E.26
Lark, M.W.27
Drake, F.H.28
Gowen, M.29
Gleason, J.G.30
Veber, D.F.31
more..
-
21
-
-
0028322950
-
Bone functional changes in intact, ovariectomized, and ovariectomized, hormone-supplemented adult cynomolgus monkeys (Macaca fascicularis
-
Jerome C. P., Carlson C. S., Register T. C., Bain F. T., Jayo M. J., Weaver D. S., Adams M. R. Bone functional changes in intact, ovariectomized, and ovariectomized, hormone-supplemented adult cynomolgus monkeys (Macaca fascicularis. J. Bone Miner. Res. 9:1994;527-540.
-
(1994)
J. Bone Miner. Res.
, vol.9
, pp. 527-540
-
-
Jerome, C.P.1
Carlson, C.S.2
Register, T.C.3
Bain, F.T.4
Jayo, M.J.5
Weaver, D.S.6
Adams, M.R.7
-
22
-
-
0026598538
-
Extraction and isolation of mRNA from adult articular cartilage
-
Adams M. E., Huang D. Q., Yao L. Y., Sandell L. J. Extraction and isolation of mRNA from adult articular cartilage. Anal Biochem. 202:1992;89-95.
-
(1992)
Anal Biochem.
, vol.202
, pp. 89-95
-
-
Adams, M.E.1
Huang, D.Q.2
Yao, L.Y.3
Sandell, L.J.4
-
23
-
-
0028123480
-
Molecular cloning of a possible cysteine proteinase predominantly expressed in osteoclasts
-
Tezuka K., Tezuka Y., Maejima A., Sato T., Nemoto K., Kamioka H., Hakeda Y., Kumegawa M. Molecular cloning of a possible cysteine proteinase predominantly expressed in osteoclasts. J. Biol. Chem. 269:1994;1106-1109.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 1106-1109
-
-
Tezuka, K.1
Tezuka, Y.2
Maejima, A.3
Sato, T.4
Nemoto, K.5
Kamioka, H.6
Hakeda, Y.7
Kumegawa, M.8
-
24
-
-
0030590476
-
Mouse cathepsin K: CDNA cloning and predominant expression of the gene in osteoclasts, and in some hypertrophying chondrocytes during mouse development
-
Rantakokko J., Aro H. T., Savontaus M., Vuorio E. Mouse cathepsin K: cDNA cloning and predominant expression of the gene in osteoclasts, and in some hypertrophying chondrocytes during mouse development. FEBS Lett. 393:1996;307-313.
-
(1996)
FEBS Lett.
, vol.393
, pp. 307-313
-
-
Rantakokko, J.1
Aro, H.T.2
Savontaus, M.3
Vuorio, E.4
-
26
-
-
0030463939
-
Cathepsin K: Isolation and characterization of the murine cDNA and genomic sequence, the homologue of the human pycnodysostosis gene
-
Gelb B. D., Moissoglu K., Zhang J., Martignetti J. A., Bromme D., Desnick R. J. Cathepsin K: Isolation and characterization of the murine cDNA and genomic sequence, the homologue of the human pycnodysostosis gene. Biochem. Mol. Med. 59:1996;200-206.
-
(1996)
Biochem. Mol. Med.
, vol.59
, pp. 200-206
-
-
Gelb, B.D.1
Moissoglu, K.2
Zhang, J.3
Martignetti, J.A.4
Bromme, D.5
Desnick, R.J.6
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