Effects of endogenous superoxide anion and nitric oxide on cholinergic constriction of normal and hyperreactive guinea pig airways

American Journal of Respiratory and Critical Care Medicine

Volumn 158, Issue 6, 1998, Pages 1784-1789

  De Boer, Jacob ^a   Pouw, F May H ^a   Zaagsma, Johan ^a   Meurs, Herman ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

METHACHOLINE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; OVALBUMIN; SUPEROXIDE; SUPEROXIDE DISMUTASE;

AIRWAY CONSTRICTION; ALLERGIC ASTHMA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRONCHUS HYPERREACTIVITY; CONTROLLED STUDY; GUINEA PIG; INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; TRACHEA;

EID: 0032430112     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.158.6.9711005     Document Type: Article

References (35)

1. G-nitro arginine inhibits non-adrenergic, non-cholinergic relaxations of guinea-pig isolated tracheal smooth muscle. Br. J. Pharmacol. 100:663-664.
2. Belvisi, M. G., C. D. Stretton, M. Yacoub, and P. J. Barnes. 1992. Nitric oxide is the endogenous neurotransmittor of bronchodilator nerves in humans. Eur. J. Pharmacol. 210:221-222.
3. G-nitro-L-arginine of nonadrenergic-noncholinergic-mediated relaxations of human isolated central and peripheral airways. Am. Rev. Respir. Dis. 146:1543-1547.
4. Munakata, M., Y. Masaki, I. Sakuma, H. Ukita, Y. Otsuka, Y. Homma, and Y. Kawakami. 1990. Pharmacological differentiation of epithelium-derived relaxing factor from nitric oxide. J. Appl. Physiol. 69: 665-670.
5. Nijkamp, F. P., H. J. Van der Linde, and G. Folkerts. 1993. Nitric oxide synthesis inhibitors induce airway hyperresponsiveness in the guinea pig in vivo and in vitro. Am. Rev. Respir. Dis. 148:727-734.
6. De Boer, J., H. Meurs, W. Coers, M. Koopal, A. E. Bottone, A. C. Visser, W. Timens, and J. Zaagsma. 1996. Deficiency of nitric oxide in allergen-induced airway hyperreactivity to contractile agonists after the early asthmatic reaction: an ex vivo study. Br. J. Pharmacol. 116:1109-1116.
7. Filep, J. G., B. Battistini, and P. Sirois. 1993. Induction of endothelin-1 of epithelium-dependent relaxation of guinea-pig trachea in vitro: role for nitric oxide. Br. J. Pharmacol. 109:637-644.
8. Figini, M., F. L. M. Ricciardolo, P. Javdan, F. P. Nijkamp, C. Emanueli, P. Pradelles, G. Folkerts, and P. Gepelti. 1996. Evidence that epithelium-derived relaxing factor released by bradykinin in the guinea pig trachea is nitric oxide. Am. J. Respir. Crit. Care Med. 153:918-923.
9. Dupuy, P. M., P. A. Shore, J. M. Drazen, C. Frostell, W. A. Hill, and W. M. Zapol. 1992. Bronchodilator action of inhaled nitric oxide in guinea pigs. J. Clin. Invest. 90:421-128.
10. Brown, R. H., E. A. Zerhouni, and C. A. Hirshman. 1994. Reversal of bronchoconstriction by inhaled nitric oxide: histamine versus methacholine. Am. J. Respir. Crit. Care Med. 150:233-237.
11. Kacmarek, R. M., R. Ripple, B. A. Cockrill, K. J. Bloch, W. M. Zapol, and D. C. Johnson. 1996. Inhaled nitric oxide: a bronchodilator in mild asthmatics with methacholine-induced bronchospasm. Am. J. Respir. Crit. Care Med. 153:128-135.
12. Persson, M. G., S. G. Friberg, P. Hedqvist, and L. E. Gustafsson. 1993. Endogenous nitric oxide counteracts antigen-induced bronchoconstriction. Eur. J. Pharmacol. 249:R7-R8.
13. Schuiling, M., A. B. Zuidhof, M. A. A. Bonouvrie, N. Venema, J. Zaagsma, and H. Meurs. 1998. Role of nitric oxide in the development and partial reversal of allergen-induced airway hyperreactivity in conscious, unrestrained guinea-pigs. Br. J. Pharmacol. 123:1450-1456.
14. Santing, R. E., H. Meurs, Th. W. M. van der Mark, R. Remie, W. C. Oosterom, F. Brouwer, and J. Zaagsma. 1992. A novel method to assess airway function parameters in chronically instrumented, unrestrained guinea pigs. Pulm. Pharmacol. 5:265-272.
15. Santing, R. E., C. G. Olymulder, J. Zaagsma, and H. Meurs. 1994. Relationships among allergen-induced early and late phase airway obstructions, bronchial hyperreactivity, and inflammation in conscious, unrestrained guinea pigs. J. Allergy Clin. Immunol. 93:1021-1030.
16. Meltzer, S., B. Goldberg, P. Lad, and J. Easton. 1989. Superoxide generation and its modulation by adenosine in the neutrophils of subjects with asthma. J. Allergy Clin. Immunol. 83:960-966.
17. Sedgwick, J. B., K. M. Geiger, and W. W. Busse. 1990. Superoxide generation by hypodense eosinophils from patients with asthma. Am. Rev. Respir. Dis. 142:120-125.
18. Barnes, P. J. 1990. Reactive oxygen species and airway inflammation. Free Radic. Biol. Med. 9:235-243.
19. Calhoun, W. J., H. E. Reed, D. R. Moest, and C. A. Stevens. 1992. Enhanced superoxide production by alveolar macrophages and air-space cells, airway inflammation, and alveolar macrophage density changes after segmental antigen bronchoprovocation in allergic subjects. Am. Rev. Respir. Dis. 145:317-325.
20. Cerasoli, F., J. Tocker, and W. M. Selig. 1991. Airway eosinophils from actively sensitized guinea pigs exhibit enhanced superoxide anion release in response to antigen challenge. Am. J. Respir. Cell Mol. Biol. 4: 195-201.
21. Huie, R. E., and S. Padmaja. 1993. The reaction of NO with superoxide. Free Radic. Res. Commun. 18:195-199.
22. Gryglewski, R. J., R. M. J. Palmer, and S. Moncada. 1986. Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor. Nature 320:454-456.
23. Ignarro, L. J., R. E. Byrns, G. M. Buga, K. S. Wood, and G. Chauduri. 1987. Pharmacological evidence that endothelium-derived relaxing factor is nitric oxide: use of pyrogallol and superoxide dismutase to study endothelium-dependent and nitric oxide-elicited vascular smooth muscle relaxation. J. Pharmacol. Exp. Ther. 244:181-189.
24. Omar, H. A., P. D. Cherry, M. P. Mortelliti, T. Burke-Wolin, and M. S. Wolin. 1991. Inhibition of coronary artery superoxide dismutase attenuates endothelium-dependent and -independent nitrovasodilator relaxation. Circ. Res. 69:601-608.
25. Chakder, S., and S. Rattan. 1991. Neurally mediated relaxation of opossum internal anal sphincter: influence of superoxide anion generator and the scavanger. J. Pharmacol. Exp. Ther. 260:1113-1118.
26. Martin, W., K. H. McAllister, and K. Paisly. 1994. NANC neurotransmission in the bovine retractor penis is blocked by superoxide anion following inhibition of superoxide dismutase with diethyldithiocarbamate. Neuropharmacology 33:1293-1301.
27. Van Amsterdam, R. G. M., F. Brouwer, and J. Zaagsma. 1989. Analysis of the β-adrenoceptor mediated inhibition of IgG- and IgE-dependent guinea pig anaphylactic tracheal smooth muscle contraction. Agents Actions 26:48-51.
28. Munakata, M., I. Huang, W. Mitzner, and H. Menkes. 1989. Protective role of epithelium in the guinea pig airway. J. Appl. Physiol. 66:1547-1552.
29. Meurs, H., and J. Zaagsma. 1991. Pharmacological and biochemical changes in airway smooth muscle in relation to bronchial hyperresponsiveness. In D. K. Agrawal and R. G. Townley, editors. Inflammatory cells and Mediators. CRC Press, Boca Raton. 1-38.
30. Kobzik, L., D. S. Bredt, C. J. Lowenstein, J. Drazen, B. Gaston, D. Sugarbaker, and J. S. Stamler. 1993. Nitric oxide synthase in human and rat lung: immunocytochemical and histochemical localization. Am. J. Respir. Cell Mol. Biol. 9:371-377.
31. Laitinen, L. A., M. Heino, A. Laitinen, T. Kava, and T. Haahtela. 1985. Damage of the airway epithelium and bronchial reactivity in patients with asthma. Am. Rev. Respir. Dis. 131:599-606.
32. Santing, R. E., Y. Hoekstra, Y. Pasman, J. Zaagsma, and H. Meurs. 1994. The importance of eosinophil activation for the development of allergen-induced bronchial hyperreactivity in conscious, unrestrained guinea-pigs. Clin. Exp. Allergy 24:1157-1163.
33. Postma, D. S., T. E. J. Renkema, J. A. Noordhoek, J. Faber, H. J. Sluiter, and H. F. Kauffman. 1988. Association between nonspecific bronchial hyperreactivity and superoxide anion production by polymorphonuclear leukocytes in chronic airflow obstruction. Am. Rev. Respir. Dis. 137:57-61.
34. Kinnula, V. L., K. B. Adler, N. S. Ackley, and J. D. Crapo. 1992. Release of reactive oxygen species by guinea pig tracheal epithelial cells in vitro. Am. J. Physiol. 262:L708-L712.
35. Ikuta, N., S. Sugiyama, K. Takagi, T. Satake, and T. Ozawa. 1992. Implication of oxygen radicals on airway hyperresponsiveness after ovalbumin challenge in guinea pigs. Am. Rev. Respir. Dis. 145:561-565.