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Volumn 18, Issue 4-6, 1998, Pages 243-263

Insulin-stimulated glycogen synthesis in cultured hepatoma cells: Differential effects of inhibitors of insulin signaling molecules

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; ENZYME INHIBITOR; GLYCOGEN; GLYCOGEN SYNTHASE; GUANINE NUCLEOTIDE BINDING PROTEIN; INSULIN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; RAPAMYCIN;

EID: 0032429163     PISSN: 10799893     EISSN: None     Source Type: Journal    
DOI: 10.3109/10799899809047746     Document Type: Article
Times cited : (14)

References (39)
  • 1
    • 0030984321 scopus 로고    scopus 로고
    • Perspectives in Diabetes: New insights into the role and mechanism of glycogen synthase activation by insulin
    • J. Lawrence and P. Roach. Perspectives in Diabetes: New insights into the role and mechanism of glycogen synthase activation by insulin. Diabetes, 1997:541-547.
    • (1997) Diabetes , pp. 541-547
    • Lawrence, J.1    Roach, P.2
  • 2
    • 77956911584 scopus 로고
    • Muscle glycogen synthase
    • P. a. K. Boyer, EG, ed. Orlando: Academic Press
    • P. Cohen. Muscle glycogen synthase. In: P. a. K. Boyer, EG, ed. The Enzymes. Orlando: Academic Press, 1986:461-497.
    • (1986) The Enzymes , pp. 461-497
    • Cohen, P.1
  • 3
    • 0002142301 scopus 로고    scopus 로고
    • Regulation of glycogen biosynthesis
    • D. LeRoith, J. Olefsky and S. Taylor, eds. Philadelphia: Lippincott-Raven Publishers
    • A. Skurat and P. Roach. Regulation of glycogen biosynthesis. In: D. LeRoith, J. Olefsky and S. Taylor, eds. Diabetes Mellitus: A Fundamental and Clinical Text. Philadelphia: Lippincott-Raven Publishers, 1996:213.
    • (1996) Diabetes Mellitus: A Fundamental and Clinical Text , pp. 213
    • Skurat, A.1    Roach, P.2
  • 4
    • 0030748457 scopus 로고    scopus 로고
    • The insulin signaling system and the IRS proteins
    • M. White. The insulin signaling system and the IRS proteins. Diabetologia, 1997:S2-S17.
    • (1997) Diabetologia
    • White, M.1
  • 5
    • 0028904053 scopus 로고
    • Insulin action and the insulin signaling network
    • B. Cheatham and R. Kahn. Insulin action and the insulin signaling network. Endocr. Rev., 1995:117-142.
    • (1995) Endocr. Rev. , pp. 117-142
    • Cheatham, B.1    Kahn, R.2
  • 6
    • 0025522071 scopus 로고
    • The molecular mechanism by which insulin stimulates glycogen synthesis in mammalian skeletal muscle
    • P. Dent, A. Lavoinne, S. Nakielny, F. Caudwell, P. Watt and P. Cohen. The molecular mechanism by which insulin stimulates glycogen synthesis in mammalian skeletal muscle. Nature, 1990:302-308.
    • (1990) Nature , pp. 302-308
    • Dent, P.1    Lavoinne, A.2    Nakielny, S.3    Caudwell, F.4    Watt, P.5    Cohen, P.6
  • 8
    • 0027935491 scopus 로고
    • Activation of ribosomal protein S6 kinase does not increase glycogen synthesis or glucose transport in rat adipocytes
    • T. Lin and J. Lawrence. Activation of ribosomal protein S6 kinase does not increase glycogen synthesis or glucose transport in rat adipocytes. Journal of Biological Chemistry, 1994:21255-21261.
    • (1994) Journal of Biological Chemistry , pp. 21255-21261
    • Lin, T.1    Lawrence, J.2
  • 9
    • 0027379099 scopus 로고
    • Mitogen-activated protein kinase activation is not sufficient for stimulation of glucose transport or glycogen synthase in 3T3-L1 adipocytes
    • L. Robinson, Z. Razzack, J. Lawrence and D. James. Mitogen-activated protein kinase activation is not sufficient for stimulation of glucose transport or glycogen synthase in 3T3-L1 adipocytes. Journal of Biological Chemistry, 1993:26422-26427.
    • (1993) Journal of Biological Chemistry , pp. 26422-26427
    • Robinson, L.1    Razzack, Z.2    Lawrence, J.3    James, D.4
  • 10
    • 0029981389 scopus 로고    scopus 로고
    • Regulation of both glycogen synthase and PHAS-1 by insulin in rat skeletal muscle involves mitogen-activated protein kinase-independent and rapamycin-sensitive pathways
    • I. Azpiazu, A. Saltiel, A. DePaoli-Roach and J. Lawrence. Regulation of both glycogen synthase and PHAS-1 by insulin in rat skeletal muscle involves mitogen-activated protein kinase-independent and rapamycin-sensitive pathways. Journal of Biological Chemistry, 1996:5033-5039.
    • (1996) Journal of Biological Chemistry , pp. 5033-5039
    • Azpiazu, I.1    Saltiel, A.2    DePaoli-Roach, A.3    Lawrence, J.4
  • 11
    • 0030442915 scopus 로고    scopus 로고
    • Insulin action in cultured human myoblasts: Contribution of different signaling pathways to regulation of glycogen synthesis
    • S. Hurel, J. Rochford, A. Borthwick, A. Wells, J. Vandenheede, D. Turnbull and S. Yeaman. Insulin action in cultured human myoblasts: contribution of different signaling pathways to regulation of glycogen synthesis. Biochemical Journal, 1996:871-877.
    • (1996) Biochemical Journal , pp. 871-877
    • Hurel, S.1    Rochford, J.2    Borthwick, A.3    Wells, A.4    Vandenheede, J.5    Turnbull, D.6    Yeaman, S.7
  • 12
    • 0028829053 scopus 로고
    • Multiple signaling pathways involved in the stimulation of fatty acid and glycogen synthesis by insulin in rat epididymal fat cells
    • S. Moule, N. Edgell, G. Welsh, T. Diggle, E. Fouston, K. Heesom, C. Proud and R. Denton. Multiple signaling pathways involved in the stimulation of fatty acid and glycogen synthesis by insulin in rat epididymal fat cells. Biochemical Journal, 1995:595-601.
    • (1995) Biochemical Journal , pp. 595-601
    • Moule, S.1    Edgell, N.2    Welsh, G.3    Diggle, T.4    Fouston, E.5    Heesom, K.6    Proud, C.7    Denton, R.8
  • 13
    • 0028797745 scopus 로고
    • Insulin stimulation of glycogen synthesis and glycogen synthase activity is blocked by wortmanin and rapamycin in 3T3-L1 adipocytes: Evidence for the involvement of phosphoinositide 3-kinase and p70 ribosomal protein S6 kinase
    • P. Shepherd, B. Nave and K. Siddle. Insulin stimulation of glycogen synthesis and glycogen synthase activity is blocked by wortmanin and rapamycin in 3T3-L1 adipocytes: evidence for the involvement of phosphoinositide 3-kinase and p70 ribosomal protein S6 kinase. Biochemical Journal, 1995:25-28.
    • (1995) Biochemical Journal , pp. 25-28
    • Shepherd, P.1    Nave, B.2    Siddle, K.3
  • 15
    • 0027978816 scopus 로고
    • The inhibition of glycogen synthase-kinase by insulin or insulin-like growth factor-1 in the rat skeletal muscle cell line L6 is blocked by wortmanin, but not by rapamycin: Evidence that wortmanin blocks activation of the mitogen-activated protein kinase pathway in L6 cells between Ras and Raf
    • D. Cross, D. Alessi, J. Vandenheede, H. McDowell, H. Hundal and P. Cohen. The inhibition of glycogen synthase-kinase by insulin or insulin-like growth factor-1 in the rat skeletal muscle cell line L6 is blocked by wortmanin, but not by rapamycin: evidence that wortmanin blocks activation of the mitogen-activated protein kinase pathway in L6 cells between Ras and Raf. Biochemical Journal, 1994:21-26.
    • (1994) Biochemical Journal , pp. 21-26
    • Cross, D.1    Alessi, D.2    Vandenheede, J.3    McDowell, H.4    Hundal, H.5    Cohen, P.6
  • 16
    • 0027515127 scopus 로고
    • Inactivation of glycogen synthase kinase-3beta by phosphorylation: New kinase connections in insulin and growth factor signaling
    • C. Sutherland, I. Leighton and P. Cohen. Inactivation of glycogen synthase kinase-3beta by phosphorylation: new kinase connections in insulin and growth factor signaling. Biochem. Journal, 1993:15-19.
    • (1993) Biochem. Journal , pp. 15-19
    • Sutherland, C.1    Leighton, I.2    Cohen, P.3
  • 17
    • 0026488401 scopus 로고
    • Identification of multifunctional ATP-citrate lyase kinase as the alpha isoform of glycogen synthase kinase 3
    • K. Hughes, S. Ramakrishna, W. Benjamin and J. Woodgett. Identification of multifunctional ATP-citrate lyase kinase as the alpha isoform of glycogen synthase kinase 3. Biochemical Journal, 1992:309-314.
    • (1992) Biochemical Journal , pp. 309-314
    • Hughes, K.1    Ramakrishna, S.2    Benjamin, W.3    Woodgett, J.4
  • 18
    • 0027430039 scopus 로고
    • Glycogen synthase kinase-3 is rapidly inactivated in response to insulin and phosphorylates eukaryotic initiation factor eIF-2B
    • G. Welsh and C. Proud. Glycogen synthase kinase-3 is rapidly inactivated in response to insulin and phosphorylates eukaryotic initiation factor eIF-2B. Biochemical Journal, 1993:625-629.
    • (1993) Biochemical Journal , pp. 625-629
    • Welsh, G.1    Proud, C.2
  • 19
    • 0025286104 scopus 로고    scopus 로고
    • Molecular cloning and expression of glycogen synthase kinase-3/factor A
    • J. R. Woodgett. Molecular cloning and expression of glycogen synthase kinase-3/factor A. EMBO J., 1990:2431-2438.
    • EMBO J. , vol.1990 , pp. 2431-2438
    • Woodgett, J.R.1
  • 21
    • 0028232158 scopus 로고
    • Role of p85 subunit of phosphatidylinositol-3-kinase as an adaptor molecule linking the insulin receptor, p62 and GTPase activating protein
    • C. Sung, V. Sanchez-Margalet and I. Goldfine. Role of p85 subunit of phosphatidylinositol-3-kinase as an adaptor molecule linking the insulin receptor, p62 and GTPase activating protein. J. Biol. Chem., 1994:12503-12507.
    • (1994) J. Biol. Chem. , pp. 12503-12507
    • Sung, C.1    Sanchez-Margalet, V.2    Goldfine, I.3
  • 23
    • 0024577114 scopus 로고
    • Human insulin receptors expressed in insulin-insensitive mouse fibroblasts couple with extant cellular effector systems to confer insulin sensitivity and responsiveness
    • C. Hofmann, M. F. White and J. Whittaker. Human insulin receptors expressed in insulin-insensitive mouse fibroblasts couple with extant cellular effector systems to confer insulin sensitivity and responsiveness. Endocrinology, 1989:257-264.
    • (1989) Endocrinology , pp. 257-264
    • Hofmann, C.1    White, M.F.2    Whittaker, J.3
  • 24
    • 0024589653 scopus 로고
    • Insulin and ribosomal protein S6 kinase in rat pancreatic acini
    • C. K. Sung and J. A. Williams. Insulin and ribosomal protein S6 kinase in rat pancreatic acini. Diabetes, 1989:544-549.
    • (1989) Diabetes , pp. 544-549
    • Sung, C.K.1    Williams, J.A.2
  • 25
    • 0027939430 scopus 로고
    • Role of Phosphatidylinositol-3-Kinase in Insulin Receptor Signaling: Studies with Inhibitor, LY294002
    • V. Sanchez-Margalet, I. D. Goldfine, C. J. Vlahos and C. K. Sung. Role Of Phosphatidylinositol-3-Kinase In Insulin Receptor Signaling: Studies With Inhibitor, LY294002. Biochem. Biophys. Res. Comm., 1994:446-452.
    • (1994) Biochem. Biophys. Res. Comm. , pp. 446-452
    • Sanchez-Margalet, V.1    Goldfine, I.D.2    Vlahos, C.J.3    Sung, C.K.4
  • 26
    • 0028308412 scopus 로고
    • Phosphatidylinositol 3-Kinase Activation Is required for Insulin Stimulation of pp70 S6 Kinase, DNA Synthesis, and Glucose Transporter Translocation
    • B. Cheatham, C. J. Vlahos, L. Cheatham, L. Wang, J. Blenis and C. R. Kahn. Phosphatidylinositol 3-Kinase Activation Is required for Insulin Stimulation of pp70 S6 Kinase, DNA Synthesis, and Glucose Transporter Translocation. Molecualr and Cellular Biology, 1994:4902-11.
    • (1994) Molecualr and Cellular Biology , pp. 4902-4911
    • Cheatham, B.1    Vlahos, C.J.2    Cheatham, L.3    Wang, L.4    Blenis, J.5    Kahn, C.R.6
  • 29
    • 16944366762 scopus 로고    scopus 로고
    • Regulation of protein kinase B and glycogen synthase kinase 3 by insulin and beta adrenergic agonists in rat epididymal fat cells
    • S. Moule, G. Welsh, N. Edgell, E. Foustone, C. Proud and R. Denton. Regulation of protein kinase B and glycogen synthase kinase 3 by insulin and beta adrenergic agonists in rat epididymal fat cells. J. Biol. Chem., 1997:7713-7719.
    • (1997) J. Biol. Chem. , pp. 7713-7719
    • Moule, S.1    Welsh, G.2    Edgell, N.3    Foustone, E.4    Proud, C.5    Denton, R.6
  • 30
    • 0023746731 scopus 로고
    • Acute regulation of hepatic protein phosphatases by glucagon, insulin and glucose
    • B. Toth, M. Bollen and W. Stalmans. Acute regulation of hepatic protein phosphatases by glucagon, insulin and glucose. J. Biol. Chem., 1988:14061-14066.
    • (1988) J. Biol. Chem. , pp. 14061-14066
    • Toth, B.1    Bollen, M.2    Stalmans, W.3
  • 32
    • 0021720063 scopus 로고
    • Insulin regulation of glycogen synthase phosphatase in primary cultures of hepatocytes
    • T. B. Miller, A. Garnache and J. Cruz. Insulin regulation of glycogen synthase phosphatase in primary cultures of hepatocytes. J. Biol. Chem., 1984:12470-12474.
    • (1984) J. Biol. Chem. , pp. 12470-12474
    • Miller, T.B.1    Garnache, A.2    Cruz, J.3
  • 33
    • 0027194749 scopus 로고
    • Dissection of the protein phosphorylation cascades involved in insulin and growth factor action
    • P. Cohen. Dissection of the protein phosphorylation cascades involved in insulin and growth factor action. Biochem. Soc. Trans., 1993:555-567.
    • (1993) Biochem. Soc. Trans. , pp. 555-567
    • Cohen, P.1
  • 34
    • 0020585165 scopus 로고
    • Glycogen synthase from rabbit skeletal muscle; effect of insulin on the state of phosphorylation of the seven phosphoserine residues in vivo
    • P. Parker, F. Caudwell and P. Cohen. Glycogen synthase from rabbit skeletal muscle; effect of insulin on the state of phosphorylation of the seven phosphoserine residues in vivo. European Journal of Biochemistry, 1983:227-234.
    • (1983) European Journal of Biochemistry , pp. 227-234
    • Parker, P.1    Caudwell, F.2    Cohen, P.3
  • 35
    • 0028346453 scopus 로고
    • Control of glycogen synthase and phosphorylase by amylin in rat skeletal muscle. Hormonal effects on the phosphorylation of phosphorylase and on the distribution of phosphate in the synthase subunit
    • J. Lawrence Jr and J. Zhang. Control of glycogen synthase and phosphorylase by amylin in rat skeletal muscle. Hormonal effects on the phosphorylation of phosphorylase and on the distribution of phosphate in the synthase subunit. J. Biol. Chem., 1994:11595-11600.
    • (1994) J. Biol. Chem. , pp. 11595-11600
    • Lawrence Jr., J.1    Zhang, J.2
  • 36
    • 0029587224 scopus 로고
    • Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
    • C. Cross, D. Alessi, P. Cohen, M. Andjelkovich and B. Hemmings. Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature, 1995:785-789.
    • (1995) Nature , pp. 785-789
    • Cross, C.1    Alessi, D.2    Cohen, P.3    Andjelkovich, M.4    Hemmings, B.5
  • 37
    • 0010733976 scopus 로고
    • Regulation of glycogen synthase: A relation of enzymatic properties with biological function
    • P. Roach and J. Larner. Regulation of glycogen synthase: a relation of enzymatic properties with biological function. Trends in Biochemical Sciences, 1976:110-112.
    • (1976) Trends in Biochemical Sciences , pp. 110-112
    • Roach, P.1    Larner, J.2
  • 38
    • 0017251870 scopus 로고
    • Rabbit skeletal muscle glycogen synthase. I. Relationship between phosphorylation state and kinetic properties
    • P. Roach, Y. Takeda and J. Larner. Rabbit skeletal muscle glycogen synthase. I. Relationship between phosphorylation state and kinetic properties. J. Biol. Chem., 1976:1913-1919.
    • (1976) J. Biol. Chem. , pp. 1913-1919
    • Roach, P.1    Takeda, Y.2    Larner, J.3
  • 39
    • 0030614364 scopus 로고    scopus 로고
    • PTG, a protein phosphatase 1-binding protein with a role in glycogen metabolism
    • J. Printen, M. Brady and A. Saltiel. PTG, a protein phosphatase 1-binding protein with a role in glycogen metabolism. Science, 1997:1475-1478.
    • (1997) Science , pp. 1475-1478
    • Printen, J.1    Brady, M.2    Saltiel, A.3


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