Spectrofluorimetric quantification of malondialdehyde for evaluation of cyclooxygenase-1/Thromboxane synthase inhibition

Archiv der Pharmazie

Volumn 331, Issue 11, 1998, Pages 359-364

  Dannhardt, Gerd ^a   Flemmer, Linda ^a   Hartmann, Rolf W ^b   Kleber, Alice ^b   Schulze, Elfriede ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b SAARLAND UNIVERSITY   (Germany)

Author keywords

Cyclooxygenase 1 thromboxane synthase inhibitors; Drug screening methods; MDA in vitro assay

Indexed keywords

ARACHIDONIC ACID; CALCIMYCIN; CYCLOOXYGENASE 1 INHIBITOR; MALONALDEHYDE; PHOSPHOLIPASE A2 INHIBITOR; THIOBARBITURIC ACID; THROMBOXANE SYNTHASE INHIBITOR; TRICHLOROACETIC ACID;

ANIMAL CELL; ARACHIDONIC ACID METABOLISM; ARTICLE; COMPETITIVE INHIBITION; CONTROLLED STUDY; DRUG DETERMINATION; DRUG SCREENING; ENZYME INHIBITION; NEGATIVE FEEDBACK; NONHUMAN; PRIORITY JOURNAL; SPECTROFLUOROMETRY; SWINE;

ANIMALS; BLOOD PLATELETS; CYCLOOXYGENASE 1; CYCLOOXYGENASE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; ENZYME INHIBITORS; HUMANS; IMIDAZOLES; ISOENZYMES; MALONDIALDEHYDE; MEMBRANE PROTEINS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; REPRODUCIBILITY OF RESULTS; SPECTROMETRY, FLUORESCENCE; SWINE; THIOBARBITURATES; THROMBOXANE-A SYNTHASE;

EID: 0032428064     PISSN: 03656233     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-4184(199811)331:11<359::AID-ARDP359>3.0.CO;2-B     Document Type: Article

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