메뉴 건너뛰기




Volumn 51, Issue 6, 1998, Pages 317-326

Intracellular accumulation of the amyloidogenic L68Q variant of human cystatin C in NIH/3T3 cells

Author keywords

Amyloidosis; Cerebral haemorrhage; Cysteine proteinase inhibitor

Indexed keywords

CYSTATIN C;

EID: 0032423707     PISSN: 13668714     EISSN: None     Source Type: Journal    
DOI: 10.1136/mp.51.6.317     Document Type: Article
Times cited : (29)

References (54)
  • 1
    • 0023159948 scopus 로고
    • Immunohistochemical characterisation of the amyloid deposits and quantitation of pertinent cerbrospinal fluid proteins in hereditary cerebral hemorrhage with amyloidosis
    • Löfberg H, Grubb A, Nilsson EK, et al. Immunohistochemical characterisation of the amyloid deposits and quantitation of pertinent cerbrospinal fluid proteins in hereditary cerebral hemorrhage with amyloidosis. Stroke 1987;18: 431-40.
    • (1987) Stroke , vol.18 , pp. 431-440
    • Löfberg, H.1    Grubb, A.2    Nilsson, E.K.3
  • 2
    • 0015466939 scopus 로고
    • Hereditary cerebral hemorrhage with amyloidosis
    • Gudmundsson G, Hallgrimsson J, Jónasson TA, et al. Hereditary cerebral hemorrhage with amyloidosis. Brain 1972;59:387-404.
    • (1972) Brain , vol.59 , pp. 387-404
    • Gudmundsson, G.1    Hallgrimsson, J.2    Jónasson, T.A.3
  • 3
    • 0023177469 scopus 로고
    • Hereditary cystatin C (γ-trace) amyloid angiopathy of the CNS causing cerebral hemorrhage
    • Jensson O, Gudmundsson G, Árnason A, et al. Hereditary cystatin C (γ-trace) amyloid angiopathy of the CNS causing cerebral hemorrhage. Acta Neurol Scand 1987;76: 102-14.
    • (1987) Acta Neurol Scand , vol.76 , pp. 102-114
    • Jensson, O.1    Gudmundsson, G.2    Árnason, A.3
  • 4
    • 0006524841 scopus 로고
    • Distribution of cystatin C amyloid deposits in icelandic patients with hereditary cystatin C amyloid angiopathy
    • Isobe T, ed. New York: Plenum Press
    • Thorsteinsson L, Blöndal H, Jensson O, et al. Distribution of cystatin C amyloid deposits in Icelandic patients with hereditary cystatin C amyloid angiopathy. In: Isobe T, ed. Amyloid and amyloidosis. New York: Plenum Press, 1988: 585-90.
    • (1988) Amyloid and Amyloidosis , pp. 585-590
    • Thorsteinsson, L.1    Blöndal, H.2    Jensson, O.3
  • 5
    • 0024824238 scopus 로고
    • Dementia in hereditary cystatin C amyloidosis
    • Iqbal K, Wisniewski HM, Winblad B, eds. New York: Alan R Liss
    • Blöndal H, Gudmundsson G, Benedikz E, et al. Dementia in hereditary cystatin C amyloidosis. In: Iqbal K, Wisniewski HM, Winblad B, eds. Alzheimer's disease and related disorders. New York: Alan R Liss, 1989:157-64.
    • (1989) Alzheimer's Disease and Related Disorders , pp. 157-164
    • Blöndal, H.1    Gudmundsson, G.2    Benedikz, E.3
  • 6
    • 0001868142 scopus 로고
    • Apoplexie und ihre vererbung
    • Arnason A. Apoplexie und ihre Vererbung. Acta Psychiatr Neurol 1035;7:1-180.
    • (1035) Acta Psychiatr Neurol , vol.7 , pp. 1-180
    • Arnason, A.1
  • 7
    • 0005616906 scopus 로고
    • Cerebral angiomata in an Icelandic family
    • Kidd, HA Cumings JN. Cerebral angiomata in an Icelandic family. Lancet 1947;i:747-8.
    • (1947) Lancet , vol.1 , pp. 747-748
    • Kidd, H.A.1    Cumings, J.N.2
  • 8
    • 0015466939 scopus 로고
    • Hereditary cerebral hemorrhage with amyloidosis
    • Gudmundsson G, Hallgrimsson J, Jonasson TA, et al. Hereditary cerebral hemorrhage with amyloidosis. Brain 1072;95:387-404.
    • (1072) Brain , vol.95 , pp. 387-404
    • Gudmundsson, G.1    Hallgrimsson, J.2    Jonasson, T.A.3
  • 9
    • 0021236724 scopus 로고
    • The place of human γ-trace (cystatin C) amongst the cysteine proteinase inhibitors
    • Barrett AJ, Davies ME, Grubb A. The place of human γ-trace (cystatin C) amongst the cysteine proteinase inhibitors. Biochem Biophys Res Commum 1984;120:631-6.
    • (1984) Biochem Biophys Res Commum , vol.120 , pp. 631-636
    • Barrett, A.J.1    Davies, M.E.2    Grubb, A.3
  • 10
    • 0040635025 scopus 로고
    • Human γ-trace, a basic microprotein: Amino acid sequence and presence in the adenohypophysis
    • Grubb A, Löfberg H. Human γ-trace, a basic microprotein: amino acid sequence and presence in the adenohypophysis. Proc Natl Acad Sci USA 1982;79:3024-7.
    • (1982) Proc Natl Acad Sci USA , vol.79 , pp. 3024-3027
    • Grubb, A.1    Löfberg, H.2
  • 11
    • 0347422215 scopus 로고
    • Nomenclature and classification of the proteins homologous with the cysteine proteinase inhibitor chicken cystatin
    • Barrett AJ, Fritz H, Grubb A, et al. Nomenclature and classification of the proteins homologous with the cysteine proteinase inhibitor chicken cystatin. Biochem J 1986;236: 312.
    • (1986) Biochem J , vol.236 , pp. 312
    • Barrett, A.J.1    Fritz, H.2    Grubb, A.3
  • 12
    • 0023024774 scopus 로고
    • Isolation of six cysteine proteinase inhibitors from human urine. Their physicochemical and enzyme kinetic properties and concentrations in biological fluids
    • Abrahamson M, Barrett AJ, Salvesen G, et al. Isolation of six cysteine proteinase inhibitors from human urine. Their physicochemical and enzyme kinetic properties and concentrations in biological fluids. J Biol Chem 1986;261: 11281-9.
    • (1986) J Biol Chem , vol.261 , pp. 11281-11289
    • Abrahamson, M.1    Barrett, A.J.2    Salvesen, G.3
  • 13
    • 0024227598 scopus 로고
    • Human cysteine proteinase inhibitors: Isolation, physiological importance, inhibitory mechanism, gene structure and relation to hereditary cerebral hemorrhage
    • Abrahamson M. Human cysteine proteinase inhibitors: isolation, physiological importance, inhibitory mechanism, gene structure and relation to hereditary cerebral hemorrhage. Scand J Clin Lab Invest 1988;48(Suppl 191):21-31.
    • (1988) Scand J Clin Lab Invest , vol.48 , Issue.SUPPL. 191 , pp. 21-31
    • Abrahamson, M.1
  • 14
    • 0024338979 scopus 로고
    • The human cystatin C gene (CST3), mutated in hereditary cystatin C amyloid angiopathy, is located on chromosome 20
    • Abrahamson M, Islam MQ, Szpirer J, et al. The human cystatin C gene (CST3), mutated in hereditary cystatin C amyloid angiopathy, is located on chromosome 20. Hum Genet 1989;82:223-6.
    • (1989) Hum Genet , vol.82 , pp. 223-226
    • Abrahamson, M.1    Islam, M.Q.2    Szpirer, J.3
  • 15
    • 0024404262 scopus 로고
    • The human cystatin C gene (CST3) is a member of the cystatin gene family which is localized on chromosome 20
    • Saitoh E, Sabatini L, Eddy RL, et al. The human cystatin C gene (CST3) is a member of the cystatin gene family which is localized on chromosome 20. Biochem Biophys Res Commun 1989;162:1324-31.
    • (1989) Biochem Biophys Res Commun , vol.162 , pp. 1324-1331
    • Saitoh, E.1    Sabatini, L.2    Eddy, R.L.3
  • 16
    • 0027210445 scopus 로고
    • Cystatin C (CST3), the candidate gene for hereditary cystatin C amyloid angiopathy (HCCAA), and other members of the cystatin gene family are clustered on chromosome 20p11.2
    • Schnittger S, Gopal Rao VVN, Abrahamson M, et al. Cystatin C (CST3), the candidate gene for hereditary cystatin C amyloid angiopathy (HCCAA), and other members of the cystatin gene family are clustered on chromosome 20p11.2. Genomics 1993;16:50-5.
    • (1993) Genomics , vol.16 , pp. 50-55
    • Schnittger, S.1    Gopal Rao, V.V.N.2    Abrahamson, M.3
  • 17
    • 0023229953 scopus 로고
    • Molecular cloning and sequence analysis of cDNA coding for the precursor of the human cysteine proteinase inhibitor cystatin C
    • Abrahamson M, Grubb A, Olafsson I, et al. Molecular cloning and sequence analysis of cDNA coding for the precursor of the human cysteine proteinase inhibitor cystatin C. FEBS Lett 1987;216:229-33.
    • (1987) FEBS Lett , vol.216 , pp. 229-233
    • Abrahamson, M.1    Grubb, A.2    Olafsson, I.3
  • 19
    • 0020604495 scopus 로고
    • Amyloid fibril in hereditary cerebral hemorrhage with amyloidosis (HCHWA) is related to the gastroentero-pancreatic neuroendocrine protein, gamma trace
    • Cohen DH, Feiner H, Jensson O, et al. Amyloid fibril in hereditary cerebral hemorrhage with amyloidosis (HCHWA) is related to the gastroentero-pancreatic neuroendocrine protein, gamma trace. J Exp Med 1983; 158:623-8.
    • (1983) J Exp Med , vol.158 , pp. 623-628
    • Cohen, D.H.1    Feiner, H.2    Jensson, O.3
  • 20
    • 0011766298 scopus 로고
    • Amyloid fibril in hereditary cerebral hemorrhage with amyloidosis of Icelandic type is a variant of γ-trace basic protein (cystatin C)
    • Ghiso J, Jensson O, Frangione B. Amyloid fibril in hereditary cerebral hemorrhage with amyloidosis of Icelandic type is a variant of γ-trace basic protein (cystatin C). Proc Natl Acad Sci USA 1986;83:2974-8.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 2974-2978
    • Ghiso, J.1    Jensson, O.2    Frangione, B.3
  • 21
    • 0023772251 scopus 로고
    • Mutation in cystatin C gene causes hereditary brain haemorrhage
    • Pálsdottir Á, Abrahamson M, Thorsteinsson L, et al. Mutation in cystatin C gene causes hereditary brain haemorrhage. Lancet 1988;ii:603-4.
    • (1988) Lancet , vol.2 , pp. 603-604
    • Pálsdottir, Á.1    Abrahamson, M.2    Thorsteinsson, L.3
  • 22
    • 0026718486 scopus 로고
    • Hereditary cystatin C amyloid angiopathy: Identification of the disease-causing mutation and specific diagnosis by polymerase chain reaction based analysis
    • Abrahamson M, Jonsdottír S, Olafsson I, et al. Hereditary cystatin C amyloid angiopathy: identification of the disease-causing mutation and specific diagnosis by polymerase chain reaction based analysis. Hum Genet 1992; 89:377-80.
    • (1992) Hum Genet , vol.89 , pp. 377-380
    • Abrahamson, M.1    Jonsdottír, S.2    Olafsson, I.3
  • 23
    • 0027976996 scopus 로고
    • Increased body temperature accelerates aggregation of the Leu-68→Gln mutant cystatin C, the amyloid-forming protein in hereditary cystatin C amyloid angiopathy
    • Abrahamson M, Grubb A. Increased body temperature accelerates aggregation of the Leu-68→Gln mutant cystatin C, the amyloid-forming protein in hereditary cystatin C amyloid angiopathy. Proc Natl Acad Sci USA 1994;91:1416-20.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 1416-1420
    • Abrahamson, M.1    Grubb, A.2
  • 24
    • 0023684074 scopus 로고
    • Efficient production of native, biologically active human cystatin C by Escherichia coli
    • Abrahamson M, Dalbøge H, Olafsson I, et al. Efficient production of native, biologically active human cystatin C by Escherichia coli. FEBS Lett 1988;236:14-18.
    • (1988) FEBS Lett , vol.236 , pp. 14-18
    • Abrahamson, M.1    Dalbøge, H.2    Olafsson, I.3
  • 25
    • 0027486180 scopus 로고
    • Processing of two homologous precursors, pro-neuropeptide Y and pro-pancreatic polypeptide, in transfected cell lines expressing different precursor convertases
    • Wulff BS, Johansen TE, Dalbøge H, et al. Processing of two homologous precursors, pro-neuropeptide Y and pro-pancreatic polypeptide, in transfected cell lines expressing different precursor convertases. J Biol Chem 1993;268: 13327-35.
    • (1993) J Biol Chem , vol.268 , pp. 13327-13335
    • Wulff, B.S.1    Johansen, T.E.2    Dalbøge, H.3
  • 26
    • 0015847039 scopus 로고
    • A new technique for the assay of infectivity of human adenovirus 5 DNA
    • Graham FL, van der Eb AJ. A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology 1973;52: 456-67.
    • (1973) Virology , vol.52 , pp. 456-467
    • Graham, F.L.1    Van Der Eb, A.J.2
  • 27
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during assembly of the head of bacteriophage T4
    • Laemmli UK. Cleavage of structural proteins during assembly of the head of bacteriophage T4. Nature 1970;227:680-5.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 28
    • 0028859421 scopus 로고
    • Promoter-mediated, dexamethasone-induced increase in cystatin C production by HeLa cells
    • Bjarnadottir M, Grubb A, Olafsson I. Promoter-mediated, dexamethasone-induced increase in cystatin C production by HeLa cells. Scand J Clin Lab Invest 1995;55:617-23.
    • (1995) Scand J Clin Lab Invest , vol.55 , pp. 617-623
    • Bjarnadottir, M.1    Grubb, A.2    Olafsson, I.3
  • 29
    • 0023784037 scopus 로고
    • Production, characterization and use of monoclonal antibodies against the major extracellular human cysteine proteinase inhibitor cystatin C and kininogen
    • Olafsson I, Löfberg H, Abrahamson M, et al. Production, characterization and use of monoclonal antibodies against the major extracellular human cysteine proteinase inhibitor cystatin C and kininogen. Scand J Clin Lab Invest 1988;48: 573-82.
    • (1988) Scand J Clin Lab Invest , vol.48 , pp. 573-582
    • Olafsson, I.1    Löfberg, H.2    Abrahamson, M.3
  • 30
    • 0029744913 scopus 로고    scopus 로고
    • Mouse and rat cystatin C: Escherichia coli production, characterization and tissue distribution
    • Hakansson K, Huh C, Grubb A, et al. Mouse and rat cystatin C: Escherichia coli production, characterization and tissue distribution. Comp Biochem Physiol 1996;114B: 303-11.
    • (1996) Comp Biochem Physiol , vol.114 B , pp. 303-311
    • Hakansson, K.1    Huh, C.2    Grubb, A.3
  • 31
    • 0017184389 scopus 로고
    • Rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding
    • Bradford MMA. Rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding. Anal Biochem 1976;72:248-54.
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.A.1
  • 32
    • 0025282543 scopus 로고
    • Identification by anti-idiotype antibodies of an intracellular membrane protein that recognizes a mammalian endoplasmic reticulum retention signal
    • Vaux D, Tooze J, Fuller S. Identification by anti-idiotype antibodies of an intracellular membrane protein that recognizes a mammalian endoplasmic reticulum retention signal. Nature 1990;345:495-502.
    • (1990) Nature , vol.345 , pp. 495-502
    • Vaux, D.1    Tooze, J.2    Fuller, S.3
  • 33
    • 0026658183 scopus 로고
    • Hepatitis B surface antigen assembles in a post-ER, pre-Golgi compartment
    • Huovila AP, Eder AM, Fuller SD. Hepatitis B surface antigen assembles in a post-ER, pre-Golgi compartment. J Cell Biol 1992;118:1305-20.
    • (1992) J Cell Biol , vol.118 , pp. 1305-1320
    • Huovila, A.P.1    Eder, A.M.2    Fuller, S.D.3
  • 34
    • 0024462447 scopus 로고
    • A novel 58-kDa protein associates with the Golgi apparatus and microtubules
    • Bloom GS, Brashear TA. A novel 58-kDa protein associates with the Golgi apparatus and microtubules. J Biol Chem 1989;264:16083-92.
    • (1989) J Biol Chem , vol.264 , pp. 16083-16092
    • Bloom, G.S.1    Brashear, T.A.2
  • 35
    • 0026729645 scopus 로고
    • Human tumour cathepsin B: Comparison with normal human liver cathepsin B
    • Moin K, Day NA, Sameni M, et al. Human tumour cathepsin B: comparison with normal human liver cathepsin B. Biochem J 1992;285:427-34.
    • (1992) Biochem J , vol.285 , pp. 427-434
    • Moin, K.1    Day, N.A.2    Sameni, M.3
  • 36
    • 0030896013 scopus 로고    scopus 로고
    • Mis-sorting of procathepsin D in metastogenic tumor cells is not due to impaired synthesis of the phosphomannosyl signal
    • Isidoro C, Baccino FM, Hasilik H. Mis-sorting of procathepsin D in metastogenic tumor cells is not due to impaired synthesis of the phosphomannosyl signal. Int J Cancer 1997;70:561-6.
    • (1997) Int J Cancer , vol.70 , pp. 561-566
    • Isidoro, C.1    Baccino, F.M.2    Hasilik, H.3
  • 37
    • 0028356053 scopus 로고
    • Latency of cathepsin B secreted by human colon carcinoma cells is not linked to secretion of cystatin C and is relieved by neutrophil elastase
    • Keppler D, Waridel P, Abrahamson M, et al. Latency of cathepsin B secreted by human colon carcinoma cells is not linked to secretion of cystatin C and is relieved by neutrophil elastase. Biochim Biophys Acta 1994;1226:117-25.
    • (1994) Biochim Biophys Acta , vol.1226 , pp. 117-125
    • Keppler, D.1    Waridel, P.2    Abrahamson, M.3
  • 38
    • 0026779586 scopus 로고
    • Cystatin C and cathepsin B in human colon carcinoma: Expression in cell lines and matrix degradation
    • Corticchiato O, Cajot J-F, Abrahamson M, et al. Cystatin C and cathepsin B in human colon carcinoma: expression in cell lines and matrix degradation. Int J Cancer 1992;52: 645-52.
    • (1992) Int J Cancer , vol.52 , pp. 645-652
    • Corticchiato, O.1    Cajot, J.-F.2    Abrahamson, M.3
  • 39
    • 0030849275 scopus 로고    scopus 로고
    • Cathepsin B and cysteine proteinase inhibitors in human lung cancer cell lines
    • Heidtmann HH, Salge U, Abrahamson M, et al. Cathepsin B and cysteine proteinase inhibitors in human lung cancer cell lines. Clin Exp Metastasis 1997;15:368-81.
    • (1997) Clin Exp Metastasis , vol.15 , pp. 368-381
    • Heidtmann, H.H.1    Salge, U.2    Abrahamson, M.3
  • 40
    • 0025358427 scopus 로고
    • Biosynthesis of peptide precursors and protease inhibitors using new constitutive and inducible eukaryotic expression vectors
    • Johansen TE, Schøller MS, Tolstoy S, et al. Biosynthesis of peptide precursors and protease inhibitors using new constitutive and inducible eukaryotic expression vectors. FEBS Lett 1990;267:289-94.
    • (1990) FEBS Lett , vol.267 , pp. 289-294
    • Johansen, T.E.1    Schøller, M.S.2    Tolstoy, S.3
  • 41
    • 0025203017 scopus 로고
    • C-Terminal KDEL-modified cystatin C is retained in transfected CHO cells
    • Johansen TE, Vogel CK, Schwartz, W. C-Terminal KDEL-modified cystatin C is retained in transfected CHO cells. Biochem Biophys Res Commun 1990;172:1384-91.
    • (1990) Biochem Biophys Res Commun , vol.172 , pp. 1384-1391
    • Johansen, T.E.1    Vogel, C.K.2
  • 42
    • 0025997518 scopus 로고
    • Processing of pro-CGRP in a rat medullary thyroid carcinoma cell line transfected with protease inhibitors
    • Johansen TE, Schifter S, Vogel CK, et al. Processing of pro-CGRP in a rat medullary thyroid carcinoma cell line transfected with protease inhibitors. Mol Endocrinol 1991;82:51-60.
    • (1991) Mol Endocrinol , vol.82 , pp. 51-60
    • Johansen, T.E.1    Schifter, S.2    Vogel, C.K.3
  • 43
    • 0026787703 scopus 로고
    • Evidence for an apical sorting signal on the ectodomain of human aminopeptidase N
    • Vogel LK, Spiess M, Sjöström H, et al. Evidence for an apical sorting signal on the ectodomain of human aminopeptidase N. J Biol Chem 1992;267:2794-7.
    • (1992) J Biol Chem , vol.267 , pp. 2794-2797
    • Vogel, L.K.1    Spiess, M.2    Sjöström, H.3
  • 44
    • 0026552528 scopus 로고
    • On the role of monocytes macrophages in the pathogenesis of central nervous system lesions in hereditary cystatin C amyloid angiopathy
    • Thorsteinsson L, Georgsson G, Asgeirsson B, et al. On the role of monocytes macrophages in the pathogenesis of central nervous system lesions in hereditary cystatin C amyloid angiopathy. J Neurol Sci 1992;108:121-8.
    • (1992) J Neurol Sci , vol.108 , pp. 121-128
    • Thorsteinsson, L.1    Georgsson, G.2    Asgeirsson, B.3
  • 45
    • 0032008123 scopus 로고    scopus 로고
    • Hereditary cystatin C amyloid angiopathy: Monitoring the presence of the Leu-68→Gln cystatin C variant in cerebrospinal fluids and monocyte cultures by MS
    • Asgeirsson B, Haebel S, Thorsteinsson L, et al. Hereditary cystatin C amyloid angiopathy: monitoring the presence of the Leu-68→Gln cystatin C variant in cerebrospinal fluids and monocyte cultures by MS. Biochem J 1998;329:497-503.
    • (1998) Biochem J , vol.329 , pp. 497-503
    • Asgeirsson, B.1    Haebel, S.2    Thorsteinsson, L.3
  • 46
    • 85038204726 scopus 로고    scopus 로고
    • Two stable unfolding intermediates of the disease-causing L68Q ariant of human cyctatin C
    • In press
    • Gerhartz B, Ekiel, Abrahamson M. Two stable unfolding intermediates of the disease-causing L68Q ariant of human cyctatin C. Biochemistry. [In press.]
    • Biochemistry
    • Gerhartz, B.1    Abrahamson, M.2
  • 47
    • 0030052426 scopus 로고    scopus 로고
    • Folding related dimerization of human cystatin C
    • Ekiel I, Abrahamson M. Folding related dimerization of human cystatin C. J Biol Chem 1996;271:1314-21.
    • (1996) J Biol Chem , vol.271 , pp. 1314-1321
    • Ekiel, I.1    Abrahamson, M.2
  • 48
    • 0031571596 scopus 로고    scopus 로고
    • NMR structural studies of human cystatin C dimers and monomers
    • Ekiel I, Abrahamson M, Fulton DB, et al. NMR structural studies of human cystatin C dimers and monomers. J Mol Biol 1997;271:266-77.
    • (1997) J Mol Biol , vol.271 , pp. 266-277
    • Ekiel, I.1    Abrahamson, M.2    Fulton, D.B.3
  • 49
    • 0021706934 scopus 로고
    • Abnormal metabolism of γ-trace alkaline microprotein: The basic defect in hereditary cerebral hemorrhage with amyloidosis
    • Grubb A, Jensson O, Gudmundsson G, et al. Abnormal metabolism of γ-trace alkaline microprotein: the basic defect in hereditary cerebral hemorrhage with amyloidosis. N Engl J Med 1984;311:1547-9.
    • (1984) N Engl J Med , vol.311 , pp. 1547-1549
    • Grubb, A.1    Jensson, O.2    Gudmundsson, G.3
  • 51
    • 0024348446 scopus 로고
    • Molecular basis of the liver and lung disease associated with the alpha 1-antitrypsin deficiency allele Mmalton
    • Curiel DT, Holmes MD, Okayama H, et al. Molecular basis of the liver and lung disease associated with the alpha 1-antitrypsin deficiency allele Mmalton. J Biol Chem 1989; 264:13938-45.
    • (1989) J Biol Chem , vol.264 , pp. 13938-13945
    • Curiel, D.T.1    Holmes, M.D.2    Okayama, H.3
  • 52
    • 0029074071 scopus 로고
    • A possible role of ER-60 protease in the degradation of misfolded proteins in the endoplasmic reticulum
    • Otsu M, Urade R, Kito M, et al. A possible role of ER-60 protease in the degradation of misfolded proteins in the endoplasmic reticulum. J Biol Chem 1995;270:14958-61.
    • (1995) J Biol Chem , vol.270 , pp. 14958-14961
    • Otsu, M.1    Urade, R.2    Kito, M.3
  • 53
    • 0023749075 scopus 로고
    • Degradation from the endoplasmic reticulum: Disposing of newly synthesized proteins
    • Lippincott-Schwartz, Bonifacino JS, Yuan LC, et al. Degradation from the endoplasmic reticulum: disposing of newly synthesized proteins. Cell 1988;54:209-20.
    • (1988) Cell , vol.54 , pp. 209-220
    • Bonifacino, J.S.1    Yuan, L.C.2
  • 54
    • 0027195933 scopus 로고
    • Seeding "one-dimensional crystallization" of amyloid: A pathogenic mechanism in Alzheimer's disease and scrapie
    • Jarrett JT, Lansbury PT Jr. Seeding "one-dimensional crystallization" of amyloid: a pathogenic mechanism in Alzheimer's disease and scrapie. Cell 1993;73:1055-8.
    • (1993) Cell , vol.73 , pp. 1055-1058
    • Jarrett, J.T.1    Lansbury P.T., Jr.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.