Identification, genomic organization, and alternative splicing of KNSL3, a novel human gene encoding a kinesin-like protein

Cytogenetics and Cell Genetics

Volumn 83, Issue 1-2, 1998, Pages 25-29

  Okamoto, S ^a   Matsushima, M ^a   Nakamura, Y ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

KINESIN; MICROTUBULE PROTEIN;

ALTERNATIVE RNA SPLICING; ARTICLE; BIODIVERSITY; CARBOXY TERMINAL SEQUENCE; CELL DIVISION; CELL ORGANELLE; CELL TRANSPORT; GENE EXPRESSION; GENE SEQUENCE; GENETIC CODE; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN TISSUE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FAMILY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TISSUE;

EID: 0032422131     PISSN: 03010171     EISSN: None     Source Type: Journal    
DOI: 10.1159/000015159     Document Type: Article

References (26)

1. Aizawa H, Sekine Y, Takemura R, Zhang Z, Nangaku M, Hirokawa N: Kinesin family in murine central nen-ous system. J Cell Biol 119:1287-1296 (1992).
2. Altschul SF, Gish W, Miller W, Meyers EW, Lipman DJ: Basic local alignment search tool. J molec Biol 215:403-410 (1990).
3. Blangy A, Lane HA, D'herin P, Happer M, Kress M, Nigg EA: Phosphorylation by p34cdc2 regulates spindle association of human EgS, a kinesin-related motor essential for bipolar spindle formation in vivo. Cell 83:1159-1169 (1995).
4. Burge C, Karlin S: Prediction of complete gene structures in human genomic DNA. J molec Biol 268:78-94 (1997).
5. Chemajovsky Y, Brown A, Clark J: Human kinesin light (beta) chain gene: DNA sequence and functional characterization of its promoter and first exon. DNA Cell Biol 15:965-974 (1996).
6. Furlong RA, Zhou CY, Ferguson-Smith MA, Affara NA: Characterization of a kinesin-related gene, ATSV, within the tuberous sclerosis locus (TSC1) candidate region on chromosome 9Q34. Genomics 33:421-429 (1996).
7. Goldstein LSB: With apologies to Scheherazade: tails of 1001 kinesin motors. A Rev Genet 27:319-351 (1993).
8. Gorlich D, Prehn S, Laskey RA, Hartmann E: Isolation of a protein that is essential for the first step of nuclear protein import. Cell 79:767-778 (1994).
9. Hirokawa N: Kinesin and dynein superfamily proteins and the mechanism of organelle transport. Science 279:519-526 (1998).
10. Nakai K, Kanehisa M: A knowledge base for predicting protein localization sites in eukaryotic cells. Genomics 14:897-911 (1992).
11. Nakamura Y, Koyama K, Matsushima M: VNTR (variable number of tandem repeat) sequences as transcriptional, translational, or functional regulators. J hum Genet 43:149-152 (1998).
12. Nakamura Y, Leppert M, O'Connell P, Wolff R, Holm T, Culver M, Martin C, Fujimoto E, Hoff M, Kumlin E, White R: Variable number of tandem repeat (VNTR) markers for human gene mapping. Science 235:1616-1622 (1987).
13. Nangaku M, Sato-Yoshitake R, Okada Y, Noda Y, Takemura R, Yamazaki H, Hirokawa N: KIF1B, a novel microtubule plus end-directed monomeric motor protein for transport of mitochondria. Cell 79:1209-1220 (1994).
14. Navone F, Niclas J, Hom-Booher N, Sparkes L, Bernstein HD, McCaffrey G, Vale RD: Cloning and expression of a human kinesin heavy chain gene: interaction of the COOH-terminal domain with cytoplasmic microtubules in transfected CV-1 cells. J Cell Biol 117:1263-1275 (1992).
15. Niclas J, Navone F, Hom-Booher N, Vale RD: Cloning and localization of a conventional kinesin motor expressed exclusively in neurons. Neuron 12:1059-1072 (1994).
16. Ogiwara A, Uchiyama I, Takagi T, Kanehisa M: Construction and analysis of a profile library characterizing groups of structurally known proteins. Protein Sci 5:1991-1999 (1996).
17. Pearson WR, Lipman DJ: Improved tools for biological sequence analysis. Proc natl Acad Sci, USA 85:1435-1441 (1988).
18. Pugliese A, Zeller M, Femandez A, Zalcberg LJ, Bartlett RJ, Ricordi C, Pietropaolo M, Eisenbarth GS, Bennett ST, Patel DD: The insulin gene is transcribed in the human thymus and transcription levels correlate with allelic variation at the INS VNTR-IDDM susceptibility locus for type 1 diabetes. Nature Genet 15:293-296 (1997).
19. Saito S, Okui K, Tokino T, Oshimura M, Nakamura Y: Isolation and mapping of 68 RFLP markers on human chromosome 6. Am J hum Genet 50:65-70 (1992).
20. Sambrook J, Fritsch EF, Maniatis T: Molecular Cloning: A Laboratory Manual, 2nd Ed (Cold Spring Harbor Laboratory, Cold Spring Harbor 1989).
21. Sekine Y, Okada Y, Noda Y, Kondo S, Aizawa H, Takemura R, Hirokawa N: A novel microtubule-based motor protein (KIF4) for organelle transport, whose expression is regulated developmentally. J Cell Biol 127:187-201 (1994).
22. Tokai N, Fijimoto-Nishiyama A, Toyoshima Y, Yonemura S, Tsukita S, Inoue J, Yamamoto T: Kid, a novel kinesin-like DNA binding protein, is localized to chromosomes and the mitotic spindle. EMBO J 15:457-467 (1996).
23. Trepicchio WL, Krontiris TG: Members of the rel/NF-kB family of transcriptional regulatory proteins bind the HRAS minisatellite DNA sequence. Nucl Acids Res 20:2427-2434 (1992).
24. Trepicchio WL, Krontiris TG: IGH minisatellite suppression of USF-binding-site and Eu-mediated transcriptional activation of the adenovirus major late promoter. Nucl Acids Res 21:977-985 (1993).
25. Uberbacher EC, Mural RJ: Locating protein-coding regions in human DNA sequences by a multiple sensor-neural network approach. Proc natl Acad Sci, USA 88:11261-11265 (1991).
26. Vafiadis P, Bennett ST, Todd JA, Nadeau J, Grabs R, Googyer CG, Wickramasinghe S, Colle E, Polychronakos C: Insulin expression in human thymus is modulated by INS VNTR alleles at the IDDM locus. Nature Genet 15:289-296 (1997).