-
1
-
-
0019410162
-
Alzheimer's disease: Evidence for selective loss of cholinergic neurons in the nucleus basalis
-
Whitehouse PJ, Price DL, Clarke AW, Coyle JT, DeLong MR. Alzheimer's disease: evidence for selective loss of cholinergic neurons in the nucleus basalis. Ann Neurol 1981; 10: 122-126.
-
(1981)
Ann Neurol
, vol.10
, pp. 122-126
-
-
Whitehouse, P.J.1
Price, D.L.2
Clarke, A.W.3
Coyle, J.T.4
DeLong, M.R.5
-
2
-
-
0027435345
-
Pharmacotherapy of Alzheimer's disease: New drugs and novel strategies
-
Giacobini E. Pharmacotherapy of Alzheimer's disease: new drugs and novel strategies. Prog Brain Res 1993; 98: 447-454.
-
(1993)
Prog Brain Res
, vol.98
, pp. 447-454
-
-
Giacobini, E.1
-
3
-
-
0002445652
-
Therapy of the cognitive deficit in Alzheimer's disease: The cholinergic system
-
eds Becker R, Giacobini E. Boston: Birkhäuser
-
Becker RE. Therapy of the cognitive deficit in Alzheimer's disease: the cholinergic system. In Cholinergic Basis for Alzheimer Therapy, eds Becker R, Giacobini E. Boston: Birkhäuser, 1991: 1-30.
-
(1991)
Cholinergic Basis for Alzheimer Therapy
, pp. 1-30
-
-
Becker, R.E.1
-
4
-
-
0026551055
-
QSAR analysis of the substituted indanone and benzylpiperidine rings of a series of indanone-benzylpiperidine inhibitors of acetylcholinesterase
-
Cardozo MG, Iimura Y, Sugimoto H, Yamanishi Y, Hopfinger AJ. QSAR analysis of the substituted indanone and benzylpiperidine rings of a series of indanone-benzylpiperidine inhibitors of acetylcholinesterase. J Med Chem 1992; 35: 584-589.
-
(1992)
J Med Chem
, vol.35
, pp. 584-589
-
-
Cardozo, M.G.1
Iimura, Y.2
Sugimoto, H.3
Yamanishi, Y.4
Hopfinger, A.J.5
-
5
-
-
0026539070
-
Conformational analysis and molecular shape comparisons of a series of indanone-benzylpiperidine inhibitors of acetylcholinesterase
-
Cardozo MG, Kawai T, Iimura Y, Sugimoto H, Yamanishi Y, Hopfinger AJ. Conformational analysis and molecular shape comparisons of a series of indanone-benzylpiperidine inhibitors of acetylcholinesterase. J Med Chem 1992; 35: 590-601.
-
(1992)
J Med Chem
, vol.35
, pp. 590-601
-
-
Cardozo, M.G.1
Kawai, T.2
Iimura, Y.3
Sugimoto, H.4
Yamanishi, Y.5
Hopfinger, A.J.6
-
6
-
-
0026757043
-
Synthesis and anti-acetylcholinesterase activity of 1-benzyl-4-[(5,6-dimethoxy-1-indanon-2-yl)methyl]piperidine hydrochloride (E2020) and related compounds
-
Sugimoto H, Iimura Y, Yamanishi Y, Yamatsu K. Synthesis and anti-acetylcholinesterase activity of 1-benzyl-4-[(5,6-dimethoxy-1-indanon-2-yl)methyl]piperidine hydrochloride (E2020) and related compounds. Biorg Med Chem Lett 1992; 2: 871-876.
-
(1992)
Biorg Med Chem Lett
, vol.2
, pp. 871-876
-
-
Sugimoto, H.1
Iimura, Y.2
Yamanishi, Y.3
Yamatsu, K.4
-
7
-
-
0028710014
-
Prediction of the binding site of 1-benzyl-4-[5,6-dimethoxy-1-indanon-2-yl] methyl piperidine in acetylcholinesterase by docking studies with the SYSDOC program
-
Pang YP, Kozikowski AP. Prediction of the binding site of 1-benzyl-4-[(5,6-dimethoxy-1-indanon-2-yl] methyl] piperidine in acetylcholinesterase by docking studies with the SYSDOC program. J Comput Aided Mol Design 1994; 8: 683-693.
-
(1994)
J Comput Aided Mol Design
, vol.8
, pp. 683-693
-
-
Pang, Y.P.1
Kozikowski, A.P.2
-
8
-
-
0000396248
-
Inhibitory action of donepezil, a novel acetylcholinesterase inhibitor, on cholinesterase. Comparison with other inhibitors
-
eds Nagatsu T, Fisher A, Yoshida M. New York: Plenum Press
-
Yamanishi Y, Ogura H, Kosasa T, Araki S, Sawa Y, Yamatsu K. Inhibitory action of donepezil, a novel acetylcholinesterase inhibitor, on cholinesterase. Comparison with other inhibitors. In Basic, Clinical, and Therapeutic Aspects of Alzheimer's and Parkinson's Diseases, Volume 2, eds Nagatsu T, Fisher A, Yoshida M. New York: Plenum Press, 1990: 409-413.
-
(1990)
Basic, Clinical, and Therapeutic Aspects of Alzheimer's and Parkinson's Diseases
, vol.2
, pp. 409-413
-
-
Yamanishi, Y.1
Ogura, H.2
Kosasa, T.3
Araki, S.4
Sawa, Y.5
Yamatsu, K.6
-
9
-
-
0029127347
-
Kinetic study on the inhibition of acetylcholinesterase by 1-benzyl-4-[(5,6-dimethoxy-1-indanon)-2-yl]methylpiperidine hydrochloride (E2020)
-
Nochi S, Asakawa N, Sato T. Kinetic study on the inhibition of acetylcholinesterase by 1-benzyl-4-[(5,6-dimethoxy-1-indanon)-2-yl]methylpiperidine hydrochloride (E2020). Biol Pharm 1995; 18: 1145-1147.
-
(1995)
Biol Pharm
, vol.18
, pp. 1145-1147
-
-
Nochi, S.1
Asakawa, N.2
Sato, T.3
-
10
-
-
0000557157
-
E2020 - The pharmacology of a piperidine cholinesterase inhibitor
-
eds Becker R, Giacobini E. Boston: Birkhäuser
-
Rogers SL, Yamanishi Y, Yamatsu K. E2020 - the pharmacology of a piperidine cholinesterase inhibitor. In Cholinergic Basis for Alzheimer Therapy, eds Becker R, Giacobini E. Boston: Birkhäuser, 1991: 314-320.
-
(1991)
Cholinergic Basis for Alzheimer Therapy
, pp. 314-320
-
-
Rogers, S.L.1
Yamanishi, Y.2
Yamatsu, K.3
-
11
-
-
0032406418
-
Pharmacokinetic and pharmacodynamic profile of donepezil HCl following multiple oral doses
-
Rogers SL, Cooper NM, Sukovaty R, Pederson JE, Lee JN, Friedhoff LT. Pharmacokinetic and pharmacodynamic profile of donepezil HCl following multiple oral doses. Br J Clin Pharmacol 1998; 46 (Suppl. 1): 7-12.
-
(1998)
Br J Clin Pharmacol
, vol.46
, Issue.SUPPL. 1
, pp. 7-12
-
-
Rogers, S.L.1
Cooper, N.M.2
Sukovaty, R.3
Pederson, J.E.4
Lee, J.N.5
Friedhoff, L.T.6
-
12
-
-
0002775701
-
Pharmacodynamics of oral E2020 and tacrine in humans: Novel approaches
-
eds Becker R, Giacobini E. Boston: Birkhäuser
-
Sherman K. Pharmacodynamics of oral E2020 and tacrine in humans: novel approaches. In Cholinergic Basis for Alzheimer Therapy, eds Becker R, Giacobini E. Boston: Birkhäuser, 1991: 321-328.
-
(1991)
Cholinergic Basis for Alzheimer Therapy
, pp. 321-328
-
-
Sherman, K.1
-
13
-
-
10244259208
-
The efficacy and safety of donepezil in patients with Alzheimer's disease: Results of a US multicenter, randomized, double-blind, placebo-controlled trial
-
Rogers SL, Friedhoff LT, the Donepezil Study Group. The efficacy and safety of donepezil in patients with Alzheimer's disease: results of a US multicenter, randomized, double-blind, placebo-controlled trial. Dementia 1996; 7: 293-303.
-
(1996)
Dementia
, vol.7
, pp. 293-303
-
-
Rogers, S.L.1
Friedhoff, L.T.2
-
14
-
-
0031883716
-
A 24-week, double-blind, placebo-controlled trial of donepezil in patients with Alzheimer's disease
-
Rogers SL, Farlow MR, Doody RS, Mohs R, Friedhoff LT, the Donepezil Study Group. A 24-week, double-blind, placebo-controlled trial of donepezil in patients with Alzheimer's disease. Neurology 1998; 50: 136-145.
-
(1998)
Neurology
, vol.50
, pp. 136-145
-
-
Rogers, S.L.1
Farlow, M.R.2
Doody, R.S.3
Mohs, R.4
Friedhoff, L.T.5
-
15
-
-
0032507788
-
Donepezil improves cognition and global function in Alzheimer's disease: A 15-week, double-blind, placebo-controlled study
-
Rogers SL, Doody RS, Mohs R, Friedhoff LT, the Donepezil Study Group. Donepezil improves cognition and global function in Alzheimer's disease: a 15-week, double-blind, placebo-controlled study. Arch Intern Med 1998; 158: 1021-1031.
-
(1998)
Arch Intern Med
, vol.158
, pp. 1021-1031
-
-
Rogers, S.L.1
Doody, R.S.2
Mohs, R.3
Friedhoff, L.T.4
-
16
-
-
0027230486
-
Pharmacokinetics of E2020 - A new compound for Alzheimer's disease, in healthy male volunteers
-
Mihara M, Ohnishi A, Tomono Y et al. Pharmacokinetics of E2020 - a new compound for Alzheimer's disease, in healthy male volunteers. Int J Clin Pharmacol Ther Toxicol 1993; 31: 223-229.
-
(1993)
Int J Clin Pharmacol Ther Toxicol
, vol.31
, pp. 223-229
-
-
Mihara, M.1
Ohnishi, A.2
Tomono, Y.3
-
17
-
-
0027141935
-
Comparison of the pharmacokinetics of E2020, a new compound for Alzheimer's disease, in healthy young and elderly subjects
-
Ohnishi A, Mihara M, Kamakura H et al. Comparison of the pharmacokinetics of E2020, a new compound for Alzheimer's disease, in healthy young and elderly subjects. J Clin Pharmacol 1993; 33: 1086-1091.
-
(1993)
J Clin Pharmacol
, vol.33
, pp. 1086-1091
-
-
Ohnishi, A.1
Mihara, M.2
Kamakura, H.3
-
18
-
-
0025985781
-
Differential inhibition of individual human liver cytochrome P-450 by cimetidine
-
Knodell RG, Browne DG, Gwozdz GP, Brian WR, Guengerich FP. Differential inhibition of individual human liver cytochrome P-450 by cimetidine. Gastroenterology 1991; 101: 1680-1691.
-
(1991)
Gastroenterology
, vol.101
, pp. 1680-1691
-
-
Knodell, R.G.1
Browne, D.G.2
Gwozdz, G.P.3
Brian, W.R.4
Guengerich, F.P.5
-
20
-
-
0001346349
-
Validation and application of an HPLC method for the determination of 1-benzyl-4-[(5,6-dimethoxy-1-indanon)-2-yl] methyl piperidine HCl (E2020) in human plasma
-
Lee JW, Rogers SL, Friedhoff LT, Stiles MR, Cooper NM. Validation and application of an HPLC method for the determination of 1-benzyl-4-[(5,6-dimethoxy-1-indanon)-2-yl] methyl piperidine HCl (E2020) in human plasma. Pharm Res 1992; 9: S350.
-
(1992)
Pharm Res
, vol.9
-
-
Lee, J.W.1
Rogers, S.L.2
Friedhoff, L.T.3
Stiles, M.R.4
Cooper, N.M.5
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