A Series of Function Blocking Antibodies against the αvβ3 Integrin Bind Allosteric to the Ligand Binding Site and Induce Ligand Dissociation

Cell Communication and Adhesion

Volumn 6, Issue 6, 1998, Pages 451-464

  Lin, Emme C k ^a   Carron, Christopher P ^b   Meyer, Debra M ^b   Smith, Jeffrey W ^a  

^a BURNHAM INSTITUTE   (United States)

^b MONSANTO COMPANY   (United States)

Author keywords

Integrin; RGD. Antibody; v 3

Indexed keywords

AMINO ACID; ARGINYLGLYCYLASPARTIC ACID; BLOCKING ANTIBODY; INTEGRIN; LIGAND; PROTEIN SUBUNIT;

ALLOSTERISM; AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ARTICLE; BINDING SITE; CELL ADHESION; COMPETITIVE INHIBITION; CONTROLLED STUDY; DISSOCIATION; FEMALE; LIGAND BINDING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN STRUCTURE;

ALLOSTERIC SITE; ANIMALS; ANTIBODIES, MONOCLONAL; CELL ADHESION; CELL LINE; CRICETINAE; EPITOPES, B-LYMPHOCYTE; HUMANS; LIGANDS; OLIGOPEPTIDES; RECEPTORS, IMMUNOLOGIC; RECEPTORS, VITRONECTIN; TUMOR CELLS, CULTURED;

ANIMALIA;

EID: 0032418834     PISSN: 15419061     EISSN: 15435180     Source Type: Journal    
DOI: 10.3109/15419069809010794     Document Type: Article

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