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Volumn 275, Issue 6 44-6, 1998, Pages

β-endorphin and natural killer cell cytolytic activity during prolonged exercise. Is there a connection?

Author keywords

Cell adhesion; Cortisol; Growth hormone; Naltrexone; Natural immunity

Indexed keywords

BETA ENDORPHIN; GROWTH HORMONE; HYDROCORTISONE; NALTREXONE;

EID: 0032415567     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.1998.275.6.r1725     Document Type: Article
Times cited : (21)

References (56)
  • 1
    • 0019818146 scopus 로고
    • Opioid binding properties of naturally occurring N- And C-terminus β-endorphins
    • Akil, H., E. Young, S. J. Watson, and D. H. Coy. Opioid binding properties of naturally occurring N- and C-terminus β-endorphins. Peptides 2:289-292, 1981.
    • (1981) Peptides , vol.2 , pp. 289-292
    • Akil, H.1    Young, E.2    Watson, S.J.3    Coy, D.H.4
  • 2
    • 0019812077 scopus 로고
    • Comparative metabolic clearance rates of beta-endorphin and beta-lipotropin in humans
    • Aronin, N., M. Wiesen, A. S. Liotta, G. C. Schussler, and D. T. Krieger. Comparative metabolic clearance rates of beta-endorphin and beta-lipotropin in humans. Life Sei. 29: 1265-1269,1981.
    • (1981) Life Sei. , vol.29 , pp. 1265-1269
    • Aronin, N.1    Wiesen, M.2    Liotta, A.S.3    Schussler, G.C.4    Krieger, D.T.5
  • 3
    • 0023185450 scopus 로고
    • The influence of naloxone on exercise-induced increase in plasma pituitary hormones and the subjectively experienced level of exhaustion in healthy males
    • Brammert, M., and B. Hokfelt. The influence of naloxone on exercise-induced increase in plasma pituitary hormones and the subjectively experienced level of exhaustion in healthy males. Acta Endocrinol. 115:125-130,1987.
    • (1987) Acta Endocrinol. , vol.115 , pp. 125-130
    • Brammert, M.1    Hokfelt, B.2
  • 4
    • 0029778125 scopus 로고    scopus 로고
    • Impact of heat exposure and moderate, intermittent exercise on cytolytic cells
    • Brenner, L, Y. D. Severs, P. N. Shek, and R. J. Shephard. Impact of heat exposure and moderate, intermittent exercise on cytolytic cells. Eur. J. Appl. Physiol, 74:162-171,1996.
    • (1996) Eur. J. Appl. Physiol , vol.74 , pp. 162-171
    • Brenner, L.1    Severs, Y.D.2    Shek, P.N.3    Shephard, R.J.4
  • 7
    • 0025678495 scopus 로고
    • Supplemental growth hormone increases the tumor cytotoxic activity of natural killer cells in healthy adults with normal growth hormone secretion
    • Grist, D. M., and J. C. Kraner. Supplemental growth hormone increases the tumor cytotoxic activity of natural killer cells in healthy adults with normal growth hormone secretion. Metabolism 39:1320-1324,1990.
    • (1990) Metabolism , vol.39 , pp. 1320-1324
    • Grist, D.M.1    Kraner, J.C.2
  • 8
    • 0030027253 scopus 로고    scopus 로고
    • Changes in corticosteroid sensitivity of peripheral blood lymphocytes after strenuous exercise in humans
    • DeRijk, R. H., J. Petrides, P. Deuster, P. W. Gold, and E. M. Sternberg. Changes in corticosteroid sensitivity of peripheral blood lymphocytes after strenuous exercise in humans. J. Clin. Endocrinol. Metab. 81:228-235,1996.
    • (1996) J. Clin. Endocrinol. Metab. , vol.81 , pp. 228-235
    • DeRijk, R.H.1    Petrides, J.2    Deuster, P.3    Gold, P.W.4    Sternberg, E.M.5
  • 9
    • 0016232364 scopus 로고
    • Calculation of percentage changes in volumes of blood, plasma, and red cells in dehydration
    • Dill, D., and D. Costill. Calculation of percentage changes in volumes of blood, plasma, and red cells in dehydration. J. Appl. Physiol. 37: 247-248,1974.
    • (1974) J. Appl. Physiol. , vol.37 , pp. 247-248
    • Dill, D.1    Costill, D.2
  • 11
    • 0024270387 scopus 로고
    • Endogenous opioids and the exerciseinduced augmentation of natural killer cell activity
    • Fiatarone, M., J. Morley, E. Bloom, D. Benton, T. Makinodan, and G. Solomon. Endogenous opioids and the exerciseinduced augmentation of natural killer cell activity. J. Lab. Clin. Med. 112:544-552,1988.
    • (1988) J. Lab. Clin. Med. , vol.112 , pp. 544-552
    • Fiatarone, M.1    Morley, J.2    Bloom, E.3    Benton, D.4    Makinodan, T.5    Solomon, G.6
  • 12
    • 0021280991 scopus 로고
    • The effect of β-endorphin on natural cytotoxicity and antibody dependent cellular cytotoxicity
    • Froelich, C., and A. Bankhurst. The effect of β-endorphin on natural cytotoxicity and antibody dependent cellular cytotoxicity. Life Sci. 35:261-265,1984.
    • (1984) Life Sci. , vol.35 , pp. 261-265
    • Froelich, C.1    Bankhurst, A.2
  • 13
    • 0031115340 scopus 로고    scopus 로고
    • Circulating levels of peripheral blood leucocytes and cytokines following competitive cycling
    • Gannon, G. A., S. G. Rhind, M. Suzui, P. N. Shek, and R. J. Shephard. Circulating levels of peripheral blood leucocytes and cytokines following competitive cycling. Can. J. Appl. Physiol. 22:133-147,1997.
    • (1997) Can. J. Appl. Physiol. , vol.22 , pp. 133-147
    • Gannon, G.A.1    Rhind, S.G.2    Suzui, M.3    Shek, P.N.4    Shephard, R.J.5
  • 14
    • 0001990920 scopus 로고
    • Natural killer cells: Modulation by intensity and duration of exercise
    • Gannon, G. A., P. N. Shek, and R. J. Shephard. Natural killer cells: modulation by intensity and duration of exercise. Exerc. Immunol. Rev. 1:26-48,1995.
    • (1995) Exerc. Immunol. Rev. , vol.1 , pp. 26-48
    • Gannon, G.A.1    Shek, P.N.2    Shephard, R.J.3
  • 17
    • 0027203152 scopus 로고
    • Interplay in vitro between ACTH, β-endorphin, and glucocorticoids in the modulation of spontaneous and lymphokine-inducible human natural killer (NK) cell activity
    • Gatti, G., R. G. Masera, L. Pallavicini, M. L. Sartori, A. Staurenghi, F. Orlandi, and A. Angeli. Interplay in vitro between ACTH, β-endorphin, and glucocorticoids in the modulation of spontaneous and lymphokine-inducible human natural killer (NK) cell activity. Brain Behav. Immun. 7:16-28,1993.
    • (1993) Brain Behav. Immun. , vol.7 , pp. 16-28
    • Gatti, G.1    Masera, R.G.2    Pallavicini, L.3    Sartori, M.L.4    Staurenghi, A.5    Orlandi, F.6    Angeli, A.7
  • 18
    • 0025361792 scopus 로고
    • Plasma beta-endorphin concentration: Response to intensity and duration of exercise
    • Goldfarb, A., B. Hatfield, D. Armstrong, and J. Potts. Plasma beta-endorphin concentration: response to intensity and duration of exercise. Med. Sei. Sports Exerc. 22:241-244,1990.
    • (1990) Med. Sei. Sports Exerc. , vol.22 , pp. 241-244
    • Goldfarb, A.1    Hatfield, B.2    Armstrong, D.3    Potts, J.4
  • 19
    • 0030878691 scopus 로고    scopus 로고
    • β-Endorphin response to exercise: An update
    • Goldfarb, A. H., and A. Z. Jamurtas. β-Endorphin response to exercise: an update. Sports Med. 24:8-16,1997.
    • (1997) Sports Med. , vol.24 , pp. 8-16
    • Goldfarb, A.H.1    Jamurtas, A.Z.2
  • 21
    • 0017737881 scopus 로고
    • β-Endorphin and adrenocorticotropin are secreted concqmitantly by the pituitary gland
    • Guillemin, R., T. Vargo, J. Rossier, S. Minick, N. Ling, C. Rivier, W. Vale, and F. Bloom. β-Endorphin and adrenocorticotropin are secreted concqmitantly by the pituitary gland. Science 197:1367-1369,1977.
    • (1977) Science , vol.197 , pp. 1367-1369
    • Guillemin, R.1    Vargo, T.2    Rossier, J.3    Minick, S.4    Ling, N.5    Rivier, C.6    Vale, W.7    Bloom, F.8
  • 22
    • 0028241784 scopus 로고
    • Flow cytometric analysis of natural killer cell function as a clinical assay
    • Hatam, L., S. Schuval, and V. Bonagura. Flow cytometric analysis of natural killer cell function as a clinical assay. Cytometry 16: 59-68,1994.
    • (1994) Cytometry , vol.16 , pp. 59-68
    • Hatam, L.1    Schuval, S.2    Bonagura, V.3
  • 23
    • 0018600854 scopus 로고
    • Specific nonopiate receptors for β-endorphin
    • Hazum, E., K.-J. Chang, and P. Cuatrecasas. Specific nonopiate receptors for β-endorphin. Science 205:1033-1035,1979.
    • (1979) Science , vol.205 , pp. 1033-1035
    • Hazum, E.1    Chang, K.-J.2    Cuatrecasas, P.3
  • 24
    • 0020518733 scopus 로고
    • Direct suppression of natural killer activity in human peripheral blood leukocyte cultures by glucocorticoids and its modulation by interferon
    • Holbrook, N. J., W. I. Cox, and H. C. Horner. Direct suppression of natural killer activity in human peripheral blood leukocyte cultures by glucocorticoids and its modulation by interferon. Cancer Res. 43:4019-4025,1983.
    • (1983) Cancer Res. , vol.43 , pp. 4019-4025
    • Holbrook, N.J.1    Cox, W.I.2    Horner, H.C.3
  • 25
    • 0031309445 scopus 로고    scopus 로고
    • Physical exercise, endogenous opioids and immune function
    • Jonsdottir, I. H., P. Hoffman, and P. Thoren. Physical exercise, endogenous opioids and immune function. Acta Physiol, Scand. 161:47-50,1997.
    • (1997) Acta Physiol, Scand. , vol.161 , pp. 47-50
    • Jonsdottir, I.H.1    Hoffman, P.2    Thoren, P.3
  • 26
    • 0029996667 scopus 로고    scopus 로고
    • Chronic intracerebroventricular administration of β-endorphin augments natural killer cell cytotoxicity in rats
    • Jonsdottir, I. H., C. Johansson, A. Asea, K. Hellstrand, P. Thoren, and P. Hoffman. Chronic intracerebroventricular administration of β-endorphin augments natural killer cell cytotoxicity in rats. Regul. Pept. 62:113-118,1996.
    • (1996) Regul. Pept. , vol.62 , pp. 113-118
    • Jonsdottir, I.H.1    Johansson, C.2    Asea, A.3    Hellstrand, K.4    Thoren, P.5    Hoffman, P.6
  • 28
    • 0021262922 scopus 로고
    • Endorphins stimulate normal human peripheral blood lymphocyte natural killer activity
    • Kay, N., J. Alien, and J. E. Morley. Endorphins stimulate normal human peripheral blood lymphocyte natural killer activity. Life Sci. 35:53-59,1984.
    • (1984) Life Sci. , vol.35 , pp. 53-59
    • Kay, N.1    Alien, J.2    Morley, J.E.3
  • 29
    • 0025112685 scopus 로고
    • Interaction between endogenous opioids and IL-2 on PHA-stimulated human lymphocytes
    • Kay, N. E., J. E. Morley, and J. I. Alien. Interaction between endogenous opioids and IL-2 on PHA-stimulated human lymphocytes. Immunology 70:485-491,1990.
    • (1990) Immunology , vol.70 , pp. 485-491
    • Kay, N.E.1    Morley, J.E.2    Alien, J.I.3
  • 30
  • 31
    • 0342566317 scopus 로고    scopus 로고
    • Effects of prolonged intense exercise on natural killer cell number and function
    • edited by C. O. Dotson and J. H. Humphrey. New York: AMS
    • Mackinnon, L. T., T. W. Chick, A. van As, and T. B. Tomasi. Effects of prolonged intense exercise on natural killer cell number and function. In: Exercise Physiology: Current Selected Research, edited by C. O. Dotson and J. H. Humphrey. New York: AMS, vol. 3,1998, p. 77-89.
    • (1998) Exercise Physiology: Current Selected Research , vol.3 , pp. 77-89
    • Mackinnon, L.T.1    Chick, T.W.2    Van As, A.3    Tomasi, T.B.4
  • 32
    • 0022640769 scopus 로고
    • β-Endorphin augments the cytolytic activity and interferon production of natural killer cells
    • Mandler, R. N., W. E. Biddison, R. Mandler, and S. A. Serrate. β-Endorphin augments the cytolytic activity and interferon production of natural killer cells. J. Immunol. 136: 934-939,1986.
    • (1986) J. Immunol. , vol.136 , pp. 934-939
    • Mandler, R.N.1    Biddison, W.E.2    Mandler, R.3    Serrate, S.A.4
  • 33
    • 0027276194 scopus 로고
    • Naloxone modulates NK cell activity of human peripheral blood lymphocytes like an opioid agonist
    • Martin-Kleiner, I. and J. Gabrilovac. Naloxone modulates NK cell activity of human peripheral blood lymphocytes like an opioid agonist. Immunopharmacol. Immunotoxicol. 15:179-197, 1993.
    • (1993) Immunopharmacol. Immunotoxicol. , vol.15 , pp. 179-197
    • Martin-Kleiner, I.1    Gabrilovac, J.2
  • 35
    • 0025810734 scopus 로고
    • Analysis of naltrexone and β-naltrexol in plasma and urine by gas chromatography/negative ion chemical ionization mass spectrometry
    • Monti, K. M., R. L. Foltz, and D. M. Chinn. Analysis of naltrexone and β-naltrexol in plasma and urine by gas chromatography/negative ion chemical ionization mass spectrometry. J. Anal Toxicol. 15:136-140,1991.
    • (1991) J. Anal Toxicol. , vol.15 , pp. 136-140
    • Monti, K.M.1    Foltz, R.L.2    Chinn, D.M.3
  • 37
    • 0022928039 scopus 로고
    • Cytotoxicity by natural killer cells: Analysis of large granular lymphocytes
    • Ortaldo, J. R. Cytotoxicity by natural killer cells: analysis of large granular lymphocytes. Methods Enzymol. 132: 445-457, 1986.
    • (1986) Methods Enzymol. , vol.132 , pp. 445-457
    • Ortaldo, J.R.1
  • 38
    • 0030847053 scopus 로고    scopus 로고
    • β-Endorphin in the immune system: A role at last?
    • Paneri, A. E., and P. Sacerdote. β-Endorphin in the immune system: a role at last? Immunol. Today 19:317-319,1997.
    • (1997) Immunol. Today , vol.19 , pp. 317-319
    • Paneri, A.E.1    Sacerdote, P.2
  • 39
    • 0028006446 scopus 로고
    • NK cell response to physical activity: Possible mechanisms of action
    • Pedersen, B., and H. Ullum. NK cell response to physical activity: possible mechanisms of action. Med. Sei. Sports Exerc. 26:140-146,1994.
    • (1994) Med. Sei. Sports Exerc. , vol.26 , pp. 140-146
    • Pedersen, B.1    Ullum, H.2
  • 40
    • 0022466229 scopus 로고
    • Characterization of the in vitro effects of glucocorticosteroids on NK cell activity
    • Pedersen, B. K., and J. M. Beyer. Characterization of the in vitro effects of glucocorticosteroids on NK cell activity. Allergy 41: 220-224,1986.
    • (1986) Allergy , vol.41 , pp. 220-224
    • Pedersen, B.K.1    Beyer, J.M.2
  • 41
    • 0023077608 scopus 로고
    • Lymphocyte hormone receptors
    • Flaut, M. Lymphocyte hormone receptors. Annu. Rev. Immunol. 5:621-669,1987.
    • (1987) Annu. Rev. Immunol. , vol.5 , pp. 621-669
    • Flaut, M.1
  • 42
    • 0022575690 scopus 로고
    • The in vitro effects of endogenous opiates on natural killer cells, antigen-specific cytolytic T cells, and T-cell subsets
    • Prete, P., E. R. Levin, and A. Pedram. The in vitro effects of endogenous opiates on natural killer cells, antigen-specific cytolytic T cells, and T-cell subsets. Exp. Neural. 92:349-359,1986.
    • (1986) Exp. Neural. , vol.92 , pp. 349-359
    • Prete, P.1    Levin, E.R.2    Pedram, A.3
  • 43
    • 33646291747 scopus 로고    scopus 로고
    • Effects of 2 h of exercise and in vivo indomethacin on circulating PGE2 levels and NK cell activity
    • 42a.Rhind, S. G., G. A. Cannon, P. N. Shek, and R. J. Shephard. Effects of 2 h of exercise and in vivo indomethacin on circulating PGE2 levels and NK cell activity (Abstract). Med. Sei. Sports Exerc. 30: S20,1998.
    • (1998) Med. Sei. Sports Exerc. , vol.30
    • Rhind, S.G.1    Cannon, G.A.2    Shek, P.N.3    Shephard, R.J.4
  • 44
    • 25744442475 scopus 로고    scopus 로고
    • Determination of natural killer cell cytolytic activity by flow cytometry: Applications in studies of exercise immunology
    • Rhind, S. G., G. A. Gannon, M. Suzui, P. N. Shek, and R. J. Shephard. Determination of natural killer cell cytolytic activity by flow cytometry: applications in studies of exercise immunology (Abstract). Int. J. Sports Med. 18: S113,1997.
    • (1997) Int. J. Sports Med. , vol.18
    • Rhind, S.G.1    Gannon, G.A.2    Suzui, M.3    Shek, P.N.4    Shephard, R.J.5
  • 45
    • 0025196196 scopus 로고
    • Human natural killer cell adhesion molecules: Differential expression after activation and participation in cytolysis
    • Robertson, M., M. Caligiuri, T. Manley, H. Levine, and J. Ritz. Human natural killer cell adhesion molecules: differential expression after activation and participation in cytolysis. J. Immunol. 145: 3194-3201,1990.
    • (1990) J. Immunol. , vol.145 , pp. 3194-3201
    • Robertson, M.1    Caligiuri, M.2    Manley, T.3    Levine, H.4    Ritz, J.5
  • 46
    • 0025639142 scopus 로고
    • Biology and clinical relevance of human natural killer cells
    • Robertson, M. J., and J. Ritz. Biology and clinical relevance of human natural killer cells. Blood 76:2421-2438,1990.
    • (1990) Blood , vol.76 , pp. 2421-2438
    • Robertson, M.J.1    Ritz, J.2
  • 47
    • 0022395235 scopus 로고
    • Functional characterization of LFA-1 antigens in the interaction of human NK clones and target cells
    • Schmidt, R. E., G. Hartley, H. Levine, S. F. Schlossman, and J. Ritz. Functional characterization of LFA-1 antigens in the interaction of human NK clones and target cells. J. ImmunoL 135:1020-1025,1985.
    • (1985) J. ImmunoL , vol.135 , pp. 1020-1025
    • Schmidt, R.E.1    Hartley, G.2    Levine, H.3    Schlossman, S.F.4    Ritz, J.5
  • 48
    • 0023848096 scopus 로고
    • T11/CD2 activation of cloned human natural killer cells results in increased conjugate formation and exocytosis of cytolytic granules
    • Schmidt, R. E., J. P. Caulfield, J. Michon, A. Hein, M. M. Kamada, R. P. MacDermott, R. L. Stevens, and J. Ritz. T11/CD2 activation of cloned human natural killer cells results in increased conjugate formation and exocytosis of cytolytic granules. J. Immunol. 140:991-1002,1988.
    • (1988) J. Immunol. , vol.140 , pp. 991-1002
    • Schmidt, R.E.1    Caulfield, J.P.2    Michon, J.3    Hein, A.4    Kamada, M.M.5    MacDermott, R.P.6    Stevens, R.L.7    Ritz, J.8
  • 49
    • 0026530634 scopus 로고
    • Changes in beta-endorphin levels in response to aerobic and anaerobic exercise
    • Schwarz, L., and W. Kindermann. Changes in beta-endorphin levels in response to aerobic and anaerobic exercise. Sports Med. 13: 25-36,1992.
    • (1992) Sports Med. , vol.13 , pp. 25-36
    • Schwarz, L.1    Kindermann, W.2
  • 50
    • 0026697429 scopus 로고
    • Acute exercise and immune function: Relationship between lymphocyte activity and changes in subset counts
    • Shinkai, S., S. Shore, P. N. Shek, and R. J. Shephard. Acute exercise and immune function: relationship between lymphocyte activity and changes in subset counts. Int. J. Sports Med. 13: 452-461,1992.
    • (1992) Int. J. Sports Med. , vol.13 , pp. 452-461
    • Shinkai, S.1    Shore, S.2    Shek, P.N.3    Shephard, R.J.4
  • 51
    • 0025740581 scopus 로고
    • Stress-induced changes in glucocorticoid receptors: Molecular mechanisms and clinical implications
    • Song, L.-N. Stress-induced changes in glucocorticoid receptors: molecular mechanisms and clinical implications. Mol. Cell. Endocrinol. 80: C171-C174,1991.
    • (1991) Mol. Cell. Endocrinol. , vol.80
    • Song, L.-N.1
  • 52
    • 0018965485 scopus 로고
    • Lack of modulation of pituitary hormone stress response by neural pathways involving opiate receptors
    • Spiler, I. J., and M. E. Molitch. Lack of modulation of pituitary hormone stress response by neural pathways involving opiate receptors. J. Clin.Endocrinol. Metab. 50: 516-520,1980.
    • (1980) J. Clin.Endocrinol. Metab. , vol.50 , pp. 516-520
    • Spiler, I.J.1    Molitch, M.E.2
  • 53
    • 0019517739 scopus 로고
    • Activation of human NKCC by moderate exercise: Increased frequency of NK cells with enhanced capability of effector-target lytic interactions
    • Targan, S., L. Britvan, and F. Dorey. Activation of human NKCC by moderate exercise: increased frequency of NK cells with enhanced capability of effector-target lytic interactions. Clin. Exp. Immunol. 45:352-360,1981.
    • (1981) Clin. Exp. Immunol. , vol.45 , pp. 352-360
    • Targan, S.1    Britvan, L.2    Dorey, F.3
  • 54
    • 0025648703 scopus 로고
    • Participation of CD11a-c/CD18, CD2 and RGD-binding receptors in endogenous and interleukin-2-stimulated NK activity of CD3-negative large granular lymphocytes
    • Timonen, T., C. G. Gahmberg, and M. Patarroyo. Participation of CD11a-c/CD18, CD2 and RGD-binding receptors in endogenous and interleukin-2-stimulated NK activity of CD3-negative large granular lymphocytes. Int. J. Cancer 46:1035-1040,1990.
    • (1990) Int. J. Cancer , vol.46 , pp. 1035-1040
    • Timonen, T.1    Gahmberg, C.G.2    Patarroyo, M.3
  • 55
    • 0017092139 scopus 로고
    • Naltrexone: Disposition, metabolism, and effects after acute and chronic dosing
    • Verebey, K., J. Volavka, S. J. Mule, and R. B. Resnick. Naltrexone: disposition, metabolism, and effects after acute and chronic dosing. Clin. Pharmacol. Ther. 20:315-328,1976.
    • (1976) Clin. Pharmacol. Ther. , vol.20 , pp. 315-328
    • Verebey, K.1    Volavka, J.2    Mule, S.J.3    Resnick, R.B.4
  • 56
    • 0023498171 scopus 로고
    • Differential effects of β-endorphin fragments on human natural killing
    • Williamson, S., R. Knight, S. Lightman, and J. Hobbs. Differential effects of β-endorphin fragments on human natural killing. Brain Behav. Immun. 1: 329-335,1987.
    • (1987) Brain Behav. Immun. , vol.1 , pp. 329-335
    • Williamson, S.1    Knight, R.2    Lightman, S.3    Hobbs, J.4


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