-
1
-
-
0016723594
-
An endotoxin-induced serum factor that causes necrosis of tumors
-
USA
-
Carswell E. A., Old L. J., Kassel R. L., Green S., Fiore N. and Williamson B. (1975) An endotoxin-induced serum factor that causes necrosis of tumors. Proc. Natl. Acad. Sci. USA 72: 3666-3670
-
(1975)
Proc. Natl. Acad. Sci.
, vol.72
, pp. 3666-3670
-
-
Carswell, E.A.1
Old, L.J.2
Kassel, R.L.3
Green, S.4
Fiore, N.5
Williamson, B.6
-
2
-
-
0025884625
-
Tumor necrosis factor. Characterization at the molecular, cellular and in vivo level
-
Fiers W. (1991) Tumor necrosis factor. Characterization at the molecular, cellular and in vivo level. FEBS Lett. 285: 199-212
-
(1991)
FEBS Lett.
, vol.285
, pp. 199-212
-
-
Fiers, W.1
-
3
-
-
0025779160
-
Tumor necrosis factor. New insights into the molecular mechanisms of its multiple actions
-
Vilcek J. and Lee T. H. (1991) Tumor necrosis factor. New insights into the molecular mechanisms of its multiple actions. J. Biol. Chem. 266: 7313-7316
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 7313-7316
-
-
Vilcek, J.1
Lee, T.H.2
-
4
-
-
0025874544
-
Biology of disease: Biologic activities and mechanisms of action of tumor necrosis factor-alpha
-
Jäätelä M. (1991) Biology of disease: biologic activities and mechanisms of action of tumor necrosis factor-alpha. Lab. Invest. 64: 724-742
-
(1991)
Lab. Invest.
, vol.64
, pp. 724-742
-
-
Jäätelä, M.1
-
5
-
-
0023697978
-
Tumor necrosis factor can induce both apoptotic and necrotic forms of cell lysis
-
Laster S. M., Wood J. G. and Gooding L. R. (1988) Tumor necrosis factor can induce both apoptotic and necrotic forms of cell lysis. J. Immunol. 141: 2629-2634
-
(1988)
J. Immunol.
, vol.141
, pp. 2629-2634
-
-
Laster, S.M.1
Wood, J.G.2
Gooding, L.R.3
-
6
-
-
0024427330
-
Alternative cleavage of the cachectin/tumor necrosis factor propeptide results in a larger, inactive form of secreted protein
-
Cseh K. and Beutler B. (1989) Alternative cleavage of the cachectin/tumor necrosis factor propeptide results in a larger, inactive form of secreted protein. J. Biol. Chem. 264: 16256-16260
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 16256-16260
-
-
Cseh, K.1
Beutler, B.2
-
7
-
-
0021949137
-
Cloning and expression in Escherichia coli of the gene for human tumour necrosis factor
-
Shirai T., Yamaguchi H., Ito H., Todd C. W. and Wallace R. B. (1985) Cloning and expression in Escherichia coli of the gene for human tumour necrosis factor. Nature 313: 803-806
-
(1985)
Nature
, vol.313
, pp. 803-806
-
-
Shirai, T.1
Yamaguchi, H.2
Ito, H.3
Todd, C.W.4
Wallace, R.B.5
-
8
-
-
0021923645
-
Human tumor necrosis factor. Production, purification and characterization
-
Aggarwal B. B., Kohr W. J., Hass P. E., Moffat B., Spencer S. A., Henzel W. J. et al. (1985) Human tumor necrosis factor. Production, purification and characterization. J. Biol. Chem. 260: 2345-2354
-
(1985)
J. Biol. Chem.
, vol.260
, pp. 2345-2354
-
-
Aggarwal, B.B.1
Kohr, W.J.2
Hass, P.E.3
Moffat, B.4
Spencer, S.A.5
Henzel, W.J.6
-
9
-
-
0024505731
-
High-level expression, purification and characterization of recombinant human tumor necrosis factor synthesized in the methylotrophic yeast Pichia pastoris
-
Sreekrishna K., Nelles L., Potenz R., Cruze J., Mazzaferro P., Fish W. et al. (1989) High-level expression, purification and characterization of recombinant human tumor necrosis factor synthesized in the methylotrophic yeast Pichia pastoris. Biochemistry 28: 4117-4125
-
(1989)
Biochemistry
, vol.28
, pp. 4117-4125
-
-
Sreekrishna, K.1
Nelles, L.2
Potenz, R.3
Cruze, J.4
Mazzaferro, P.5
Fish, W.6
-
10
-
-
0024357657
-
The structure of tumor necrosis factor-alpha at 2.6 Å resolution. Implications for receptor binding
-
Eck M. J. and Sprang S. R. (1989) The structure of tumor necrosis factor-alpha at 2.6 Å resolution. Implications for receptor binding. J. Biol. Chem. 264: 17595-17605
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 17595-17605
-
-
Eck, M.J.1
Sprang, S.R.2
-
12
-
-
0030459292
-
Tumor necrosis factor and interferon are selectively cytostatic for hormone-dependent and hormone-independent human breast cancer cells
-
Mueller H., Flury N., Liu R., Scheidegger S., Kueng W. and Eppenberger U. (1996) Tumor necrosis factor and interferon are selectively cytostatic for hormone-dependent and hormone-independent human breast cancer cells. Eur. J. Cancer 32A: 2312-2318
-
(1996)
Eur. J. Cancer
, vol.32 A
, pp. 2312-2318
-
-
Mueller, H.1
Flury, N.2
Liu, R.3
Scheidegger, S.4
Kueng, W.5
Eppenberger, U.6
-
13
-
-
0028349539
-
Molecular mechanisms of tumor necrosis factor-induced cytotoxicity. What we do understand and what we do not
-
Beyaert R. and Fiers W. (1994) Molecular mechanisms of tumor necrosis factor-induced cytotoxicity. What we do understand and what we do not. FEBS Lett. 340: 9-16
-
(1994)
FEBS Lett.
, vol.340
, pp. 9-16
-
-
Beyaert, R.1
Fiers, W.2
-
15
-
-
0028277663
-
Unraveling function in the TNF ligand and receptor families
-
Beutler B. and van Huffel C. (1994) Unraveling function in the TNF ligand and receptor families. Science 264: 667-668
-
(1994)
Science
, vol.264
, pp. 667-668
-
-
Beutler, B.1
Van Huffel, C.2
-
16
-
-
0025269050
-
Molecular cloning and expression of the human 55 kD tumor necrosis factor receptor
-
Loetscher H., Pan Y.-C. E., Lahm H.-W., Gentz R., Brockhaus M., Tabuchi H. et al. (1990) Molecular cloning and expression of the human 55 kD tumor necrosis factor receptor. Cell 61: 351-359
-
(1990)
Cell
, vol.61
, pp. 351-359
-
-
Loetscher, H.1
Pan, Y.-C.E.2
Lahm, H.-W.3
Gentz, R.4
Brockhaus, M.5
Tabuchi, H.6
-
17
-
-
0025711127
-
Molecular cloning and expression of a receptor for human tumor necrosis factor
-
Schall T. J., Lewis M., Koller K. J., Lee A., Rice G. C., Wong G. H. et al. (1990) Molecular cloning and expression of a receptor for human tumor necrosis factor. Cell 61: 361-370
-
(1990)
Cell
, vol.61
, pp. 361-370
-
-
Schall, T.J.1
Lewis, M.2
Koller, K.J.3
Lee, A.4
Rice, G.C.5
Wong, G.H.6
-
18
-
-
0025113598
-
Soluble forms of tumor necrosis factor receptors (TNF-Rs). The cDNA for the type I TNF-R. Cloned using ammo acid sequence data of its soluble form, encodes both the cell surface and a soluble form of the receptor
-
Nophar Y., Kemper O., Brakebusch C., Englemann H., Zwang R., Aderka D. et al. (1990) Soluble forms of tumor necrosis factor receptors (TNF-Rs). The cDNA for the type I TNF-R. cloned using ammo acid sequence data of its soluble form, encodes both the cell surface and a soluble form of the receptor. EMBO J. 9: 3269-3278
-
(1990)
EMBO J.
, vol.9
, pp. 3269-3278
-
-
Nophar, Y.1
Kemper, O.2
Brakebusch, C.3
Englemann, H.4
Zwang, R.5
Aderka, D.6
-
19
-
-
0025695044
-
Molecular cloning and expression of human and rat tumor necrosis factor receptor chain (p60) and its soluble derivative, tumor necrosis factor-binding protein
-
Himmler A., Maurer-Fogy I., Kronke M., Scheurich P., Pfizenmaier K., Lantz M. et al. (1990) Molecular cloning and expression of human and rat tumor necrosis factor receptor chain (p60) and its soluble derivative, tumor necrosis factor-binding protein. DNA Cell Biol. 9: 705-715
-
(1990)
DNA Cell Biol.
, vol.9
, pp. 705-715
-
-
Himmler, A.1
Maurer-Fogy, I.2
Kronke, M.3
Scheurich, P.4
Pfizenmaier, K.5
Lantz, M.6
-
20
-
-
0025096274
-
A second tumor necrosis factor receptor gene product can shed a naturally occurring tumor necrosis factor inhibitor
-
USA
-
Kohno T., Brewer M. T., Baker S. L., Schwartz P. E., King M. W., Hale K. K. et al. (1990) A second tumor necrosis factor receptor gene product can shed a naturally occurring tumor necrosis factor inhibitor. Proc. Natl. Acad. Sci. USA 87: 8331-8335
-
(1990)
Proc. Natl. Acad. Sci.
, vol.87
, pp. 8331-8335
-
-
Kohno, T.1
Brewer, M.T.2
Baker, S.L.3
Schwartz, P.E.4
King, M.W.5
Hale, K.K.6
-
21
-
-
0025313006
-
A receptor for tumor necrosis factor defines an unusual family of cellular and viral proteins
-
Smith C. A., Davis T., Anderson D., Solam L., Beckmann M. P., Jerzy R. et al. (1990) A receptor for tumor necrosis factor defines an unusual family of cellular and viral proteins. Science 248: 1019-1023
-
(1990)
Science
, vol.248
, pp. 1019-1023
-
-
Smith, C.A.1
Davis, T.2
Anderson, D.3
Solam, L.4
Beckmann, M.P.5
Jerzy, R.6
-
22
-
-
0025000579
-
Cloning of human tumor necrosis factor (TNF) receptor cDNA and expression of recombinant soluble TNF-binding protein
-
USA
-
Gray P. W., Barrett K., Chantry D., Turner M. and Feldmann M. (1990) Cloning of human tumor necrosis factor (TNF) receptor cDNA and expression of recombinant soluble TNF-binding protein. Proc. Natl. Acad. Sci. USA 87: 7380-7384
-
(1990)
Proc. Natl. Acad. Sci.
, vol.87
, pp. 7380-7384
-
-
Gray, P.W.1
Barrett, K.2
Chantry, D.3
Turner, M.4
Feldmann, M.5
-
23
-
-
0028598856
-
Cloning, sequencing and partial functional characterization of the 5′ region of the human p75 tumor necrosis factor receptor-encoding gene (TNF-R)
-
Kuhnert P., Kemper O. and Wallach D. (1994) Cloning, sequencing and partial functional characterization of the 5′ region of the human p75 tumor necrosis factor receptor-encoding gene (TNF-R). Gene 150: 381-386
-
(1994)
Gene
, vol.150
, pp. 381-386
-
-
Kuhnert, P.1
Kemper, O.2
Wallach, D.3
-
24
-
-
0031882913
-
The type 1 receptor (CD120a) is the high-affinity receptor for soluble tumor necrosis factor
-
USA
-
Grell M., Wajant H., Zimmermann G. and Scheurich P. (1998) The type 1 receptor (CD120a) is the high-affinity receptor for soluble tumor necrosis factor. Proc. Natl. Acad. Sci. USA 95: 570-575
-
(1998)
Proc. Natl. Acad. Sci.
, vol.95
, pp. 570-575
-
-
Grell, M.1
Wajant, H.2
Zimmermann, G.3
Scheurich, P.4
-
25
-
-
0026778831
-
Human 55-kDa receptor for tumor necrosis factor coupled to signal transduction cascades
-
Wiegmann K., Schutze S., Kampen E., Himmler A., Machleidt T. and Kronke M. (1992) Human 55-kDa receptor for tumor necrosis factor coupled to signal transduction cascades. J. Biol. Chem. 267: 17997-18001
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 17997-18001
-
-
Wiegmann, K.1
Schutze, S.2
Kampen, E.3
Himmler, A.4
Machleidt, T.5
Kronke, M.6
-
26
-
-
0027308663
-
Tumor necrosis factor's cytotoxic activity is signaled by the p55 TNF receptor
-
Tartaglia L. A., Rothe M., Hu Y.-F. and Goeddel D. V. (1993) Tumor necrosis factor's cytotoxic activity is signaled by the p55 TNF receptor. Cell 73: 213-216
-
(1993)
Cell
, vol.73
, pp. 213-216
-
-
Tartaglia, L.A.1
Rothe, M.2
Hu, Y.-F.3
Goeddel, D.V.4
-
27
-
-
0028297068
-
The sphingomyelin pathway in tumor necrosis factor and interleukin-1 signalling
-
Kolesinck R. and Golde D. W. (1994) The sphingomyelin pathway in tumor necrosis factor and interleukin-1 signalling. Cell 77: 325-328
-
(1994)
Cell
, vol.77
, pp. 325-328
-
-
Kolesinck, R.1
Golde, D.W.2
-
28
-
-
0026458406
-
TNF activates NF-kappa B by phosphatidylcholine-specific phospholipase C-induced 'acidic' sphingomyelin breakdown
-
Schutze S., Potthoff K., Machleidt T., Berkovic D., Wiegmann K. and Kronke M. (1992) TNF activates NF-kappa B by phosphatidylcholine-specific phospholipase C-induced 'acidic' sphingomyelin breakdown. Cell 71: 765-776
-
(1992)
Cell
, vol.71
, pp. 765-776
-
-
Schutze, S.1
Potthoff, K.2
Machleidt, T.3
Berkovic, D.4
Wiegmann, K.5
Kronke, M.6
-
29
-
-
0023628781
-
Expression of tumor necrosis factor receptors on human monocytes and internalization of receptor bound ligand
-
Imamura K., Spriggs D. and Kufe D. (1987) Expression of tumor necrosis factor receptors on human monocytes and internalization of receptor bound ligand. J. Immunol. 139: 2989-2992
-
(1987)
J. Immunol.
, vol.139
, pp. 2989-2992
-
-
Imamura, K.1
Spriggs, D.2
Kufe, D.3
-
30
-
-
0242453490
-
Tumor necrosis factor: Specific binding and internalization in sensitive and resistant cells
-
USA
-
Tsujimoto M., Yip Y. K. and Vilcek J. (1985) Tumor necrosis factor: specific binding and internalization in sensitive and resistant cells. Proc. Natl. Acad. Sci. USA 82: 7626-7630
-
(1985)
Proc. Natl. Acad. Sci.
, vol.82
, pp. 7626-7630
-
-
Tsujimoto, M.1
Yip, Y.K.2
Vilcek, J.3
-
31
-
-
0023947116
-
Tumor necrosis factor receptors and cytocidal activity are down-regulated by activators of protein kinase C
-
Johnson S. E. and Baglioni C. (1988) Tumor necrosis factor receptors and cytocidal activity are down-regulated by activators of protein kinase C. J. Biol. Chem. 263: 5686-5692
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 5686-5692
-
-
Johnson, S.E.1
Baglioni, C.2
-
32
-
-
0023525917
-
Downregulation of tumor necrosis factor (TNF) sensitivity via modulation of TNF binding capacity by protein kinase C activators
-
Unglaub R., Maxeiner B., Thoma B., Pfizenmaier K. and Scheurich P. (1987) Downregulation of tumor necrosis factor (TNF) sensitivity via modulation of TNF binding capacity by protein kinase C activators. J. Exp. Med. 166: 1788-1797
-
(1987)
J. Exp. Med.
, vol.166
, pp. 1788-1797
-
-
Unglaub, R.1
Maxeiner, B.2
Thoma, B.3
Pfizenmaier, K.4
Scheurich, P.5
-
33
-
-
0023646055
-
Effect of phorbol esters on down-regulation and redistribution of cell surface receptors for tumor necrosis factor-alpha
-
Aggarwal B. B. and Eessalu T. E. (1987) Effect of phorbol esters on down-regulation and redistribution of cell surface receptors for tumor necrosis factor-alpha. J. Biol. Chem. 262: 16450-16455
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 16450-16455
-
-
Aggarwal, B.B.1
Eessalu, T.E.2
-
34
-
-
0023691058
-
Continuous internalization of tumor necrosis factor receptors in a human myosarcoma cell line
-
Watanabe N., Kuriyama H., Sone H., Neda H., Yamauchi N., Maeda M. et al. (1988) Continuous internalization of tumor necrosis factor receptors in a human myosarcoma cell line. J. Biol. Chem. 263: 10262-10266
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 10262-10266
-
-
Watanabe, N.1
Kuriyama, H.2
Sone, H.3
Neda, H.4
Yamauchi, N.5
Maeda, M.6
-
35
-
-
0024805774
-
Recycling of tumor necrosis factor-alpha receptor in MCF-7 cells
-
Vuk-Pavlovic S. and Kovach J. S. (1989) Recycling of tumor necrosis factor-alpha receptor in MCF-7 cells. FASEB J. 3: 2633-2640
-
(1989)
FASEB J.
, vol.3
, pp. 2633-2640
-
-
Vuk-Pavlovic, S.1
Kovach, J.S.2
-
36
-
-
0024364294
-
Binding, internalization and intracellular processing of proteins interacting with recycling receptors. A kinetic analysis
-
Bajzer Z., Myers A. C. and Vuk-Pavlovic S. (1989) Binding, internalization and intracellular processing of proteins interacting with recycling receptors. A kinetic analysis. J. Biol. Chem. 264: 13623-13631
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 13623-13631
-
-
Bajzer, Z.1
Myers, A.C.2
Vuk-Pavlovic, S.3
-
37
-
-
0028351535
-
TNF induces internalization of the p60 receptor and shedding of the p80 receptor
-
Higuchi M. and Aggarwal B. B. (1994) TNF induces internalization of the p60 receptor and shedding of the p80 receptor. J. Immunol. 152: 3550-3558
-
(1994)
J. Immunol.
, vol.152
, pp. 3550-3558
-
-
Higuchi, M.1
Aggarwal, B.B.2
-
38
-
-
0027934198
-
Tumor necrosis factor induces a selective shedding of its p75 receptor from human neutrophils
-
Porteu F. and Hieblot C. (1994) Tumor necrosis factor induces a selective shedding of its p75 receptor from human neutrophils. J. Biol. Chem. 269: 2834-2840
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 2834-2840
-
-
Porteu, F.1
Hieblot, C.2
-
39
-
-
0028051730
-
Role of sulfhydryl groups in induction of cell surface down-modulation and shedding of extracellular domain of human TNF receptors in human histiocytic lymphoma U937 cells
-
Zhang L. and Aggarwal B. B. (1994) Role of sulfhydryl groups in induction of cell surface down-modulation and shedding of extracellular domain of human TNF receptors in human histiocytic lymphoma U937 cells. J. Immunol. 153: 3745-3754
-
(1994)
J. Immunol.
, vol.153
, pp. 3745-3754
-
-
Zhang, L.1
Aggarwal, B.B.2
-
40
-
-
0030481448
-
In vitro comparison of inhibiting ability of soluble TNF receptor p75 (TBP II) vs. soluble TNF receptor p55 (TBP 1) against TNF-alpha and TNF-beta
-
Terlizzese M., Simoni P. and Antonetti F. (1996) In vitro comparison of inhibiting ability of soluble TNF receptor p75 (TBP II) vs. soluble TNF receptor p55 (TBP 1) against TNF-alpha and TNF-beta. J. Interferon Cytokine Res. 16: 1047-1053
-
(1996)
J. Interferon Cytokine Res.
, vol.16
, pp. 1047-1053
-
-
Terlizzese, M.1
Simoni, P.2
Antonetti, F.3
-
41
-
-
0025204833
-
Purification and characterization of an inhibitor (soluble tumor necrosis factor receptor) for tumor necrosis factor and lymphotoxin obtained from the serum ultrafiltrates of human cancer patients
-
USA
-
Gatanaga T., Hwang C. D., Kohr W., Cappuccini F., Lucci J. A. D., Jeffes E. W. et al. (1990) Purification and characterization of an inhibitor (soluble tumor necrosis factor receptor) for tumor necrosis factor and lymphotoxin obtained from the serum ultrafiltrates of human cancer patients. Proc. Natl. Acad. Sci. USA 87: 8781-8784
-
(1990)
Proc. Natl. Acad. Sci.
, vol.87
, pp. 8781-8784
-
-
Gatanaga, T.1
Hwang, C.D.2
Kohr, W.3
Cappuccini, F.4
Lucci, J.A.D.5
Jeffes, E.W.6
-
42
-
-
0027392199
-
Human TNF mutants with selective activity on the p55 receptor
-
Van Ostade X., Vandenabeele P., Everaerdt B., Loetscher H., Gentz R., Brockhaus M. et al. (1993) Human TNF mutants with selective activity on the p55 receptor. Nature 361: 266-269
-
(1993)
Nature
, vol.361
, pp. 266-269
-
-
Van Ostade, X.1
Vandenabeele, P.2
Everaerdt, B.3
Loetscher, H.4
Gentz, R.5
Brockhaus, M.6
-
43
-
-
0028176580
-
Dissociation of TNF-alpha cytotoxic and proinflammatory activities by p55 receptor- and p75 receptor-selective TNF-alpha mutants
-
Barbara J. A., Smith W. B., Gamble J. R., Van Ostade X., Vandenabecle P., Tavernier J. et al. (1994) Dissociation of TNF-alpha cytotoxic and proinflammatory activities by p55 receptor- and p75 receptor-selective TNF-alpha mutants. EMBO J. 13: 843-850
-
(1994)
EMBO J.
, vol.13
, pp. 843-850
-
-
Barbara, J.A.1
Smith, W.B.2
Gamble, J.R.3
Van Ostade, X.4
Vandenabecle, P.5
Tavernier, J.6
-
44
-
-
0025098536
-
Characterization of binding and biological effects of monoclonal antibodies against a human tumor necrosis factor receptor
-
Espevik T., Brockhaus M., Loetscher H., Nonstad U. and Shalaby R. (1990) Characterization of binding and biological effects of monoclonal antibodies against a human tumor necrosis factor receptor. J. Exp. Med. 171: 415-426
-
(1990)
J. Exp. Med.
, vol.171
, pp. 415-426
-
-
Espevik, T.1
Brockhaus, M.2
Loetscher, H.3
Nonstad, U.4
Shalaby, R.5
-
45
-
-
0025107818
-
Identification of a 60-kD tumor necrosis factor (TNF) receptor as the major signal transducing component in TNF responses
-
Thoma B., Grell M., Pfizenmaier K. and Scheurich P. (1990) Identification of a 60-kD tumor necrosis factor (TNF) receptor as the major signal transducing component in TNF responses. J. Exp. Med. 172: 1019-1023
-
(1990)
J. Exp. Med.
, vol.172
, pp. 1019-1023
-
-
Thoma, B.1
Grell, M.2
Pfizenmaier, K.3
Scheurich, P.4
-
46
-
-
0026563754
-
Cytoplasmic truncation of the p55 tumour necrosis factor (TNF) receptor abolishes signalling, but not induced shedding of the receptor
-
Brakebusch C., Nophar Y., Kemper O., Engelmann H. and Wallach D. (1992) Cytoplasmic truncation of the p55 tumour necrosis factor (TNF) receptor abolishes signalling, but not induced shedding of the receptor. EMBO J. 11: 943-950
-
(1992)
EMBO J.
, vol.11
, pp. 943-950
-
-
Brakebusch, C.1
Nophar, Y.2
Kemper, O.3
Engelmann, H.4
Wallach, D.5
-
47
-
-
0026744103
-
Tumor necrosis factor receptor signaling. A dominant negative mutation suppresses the activation of the 55-kDa tumor necrosis factor receptor
-
Tartaglia L. A. and Goeddel D. V. (1992) Tumor necrosis factor receptor signaling. A dominant negative mutation suppresses the activation of the 55-kDa tumor necrosis factor receptor. J. Biol. Chem. 267: 4304-4307
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 4304-4307
-
-
Tartaglia, L.A.1
Goeddel, D.V.2
-
48
-
-
0026072837
-
The two different receptors for tumor necrosis factor mediate distinct cellular responses
-
USA
-
Tartaglia L. A., Weber R. F., Figari I. S., Reynolds C. Palladino M. A. Jr. and Goeddel D. V. (1991) The two different receptors for tumor necrosis factor mediate distinct cellular responses. Proc. Natl. Acad. Sci. USA 88: 9292-9296
-
(1991)
Proc. Natl. Acad. Sci.
, vol.88
, pp. 9292-9296
-
-
Tartaglia, L.A.1
Weber, R.F.2
Figari, I.S.3
Reynolds, C.4
Palladino M.A., Jr.5
Goeddel, D.V.6
-
49
-
-
0028337454
-
Dual role of the p75 tumor necrosis factor (TNF) receptor in TNF cytotoxicity
-
Bigda J., Beletsky I., Brakebusch C., Varfolomeev Y., Engelmann H., Holtmann H. et al. (1994) Dual role of the p75 tumor necrosis factor (TNF) receptor in TNF cytotoxicity. J. Exp. Med. 180: 445-460
-
(1994)
J. Exp. Med.
, vol.180
, pp. 445-460
-
-
Bigda, J.1
Beletsky, I.2
Brakebusch, C.3
Varfolomeev, Y.4
Engelmann, H.5
Holtmann, H.6
-
50
-
-
0028588613
-
Mechanisms of tumor necrosis factor cytotoxicity and the cytotoxic signals transduced by the p75-tumor necrosis factor receptor
-
Reid T., Louie P. and Heller R. A. (1994) Mechanisms of tumor necrosis factor cytotoxicity and the cytotoxic signals transduced by the p75-tumor necrosis factor receptor. Circ. Shock 44: 84-90
-
(1994)
Circ. Shock
, vol.44
, pp. 84-90
-
-
Reid, T.1
Louie, P.2
Heller, R.A.3
-
51
-
-
0028674458
-
Functional requirement of the two TNF receptors for induction of apoptosis in PC60 cells and the role of mitochondria in TNF-induced cytotoxicity
-
Vandenabeele P., Goossens V., Beyaert R., Declercq W., Grooten J., Vanhaesebroeck B. et al. (1994) Functional requirement of the two TNF receptors for induction of apoptosis in PC60 cells and the role of mitochondria in TNF-induced cytotoxicity. Circ. Shock 44: 196-200
-
(1994)
Circ. Shock
, vol.44
, pp. 196-200
-
-
Vandenabeele, P.1
Goossens, V.2
Beyaert, R.3
Declercq, W.4
Grooten, J.5
Vanhaesebroeck, B.6
-
52
-
-
0028930776
-
Both TNF receptors are required for TNF-mediated induction of apoptosis in PC60 cells
-
Vandenabeele P., Declercq W., Vanhaesebroeck B., Grooten J. and Fiers W. (1995) Both TNF receptors are required for TNF-mediated induction of apoptosis in PC60 cells. J. Immunol. 154: 2904-2913
-
(1995)
J. Immunol.
, vol.154
, pp. 2904-2913
-
-
Vandenabeele, P.1
Declercq, W.2
Vanhaesebroeck, B.3
Grooten, J.4
Fiers, W.5
-
53
-
-
0031803058
-
Cooperation of both TNF receptors in inducing apoptosis: Involvement of the TNF receptor-associated factor binding domain of the TNF receptor 75
-
Declercq W., Denecker G., Fiers W. and Vandenabeele P. (1998) Cooperation of both TNF receptors in inducing apoptosis: involvement of the TNF receptor-associated factor binding domain of the TNF receptor 75. J. Immunol. 161: 390-399
-
(1998)
J. Immunol.
, vol.161
, pp. 390-399
-
-
Declercq, W.1
Denecker, G.2
Fiers, W.3
Vandenabeele, P.4
-
54
-
-
84963086839
-
Chemical treatment of tumors. V. Isolation of the hemorrhage-producing fraction from Serratia marcescens (Bacillus prodigiosus) culture filtrate
-
Shear M. J., Turner F. C. and Perrault A. (1943) Chemical treatment of tumors. V. Isolation of the hemorrhage-producing fraction from Serratia marcescens (Bacillus prodigiosus) culture filtrate. J. Natl. Cancer Inst. 4: 81-97
-
(1943)
J. Natl. Cancer Inst.
, vol.4
, pp. 81-97
-
-
Shear, M.J.1
Turner, F.C.2
Perrault, A.3
-
55
-
-
0031464924
-
Biologic response modulation by tumor necrosis factor alpha (TNF alpha) in a phase Ib trial in cancer patients
-
Logan T. F., Gooding W. E., Whiteside T. L., Ernstoff M. S., Kaplan S. S., Miketic L. et al. (1997) Biologic response modulation by tumor necrosis factor alpha (TNF alpha) in a phase Ib trial in cancer patients. J. Immunother. 20: 387-398
-
(1997)
J. Immunother.
, vol.20
, pp. 387-398
-
-
Logan, T.F.1
Gooding, W.E.2
Whiteside, T.L.3
Ernstoff, M.S.4
Kaplan, S.S.5
Miketic, L.6
-
57
-
-
0025856680
-
Phase I trial of intravenously administered endotoxin (Salmonella abortus equi) in cancer patients
-
Engelhardt R., Mackensen A. and Galanos C. (1991) Phase I trial of intravenously administered endotoxin (Salmonella abortus equi) in cancer patients. Cancer Res. 51: 2524-2530
-
(1991)
Cancer Res.
, vol.51
, pp. 2524-2530
-
-
Engelhardt, R.1
Mackensen, A.2
Galanos, C.3
-
58
-
-
0004753309
-
Phase II trial of intravenous endotoxin in patients with colorectal and non-small cell lung cancer
-
Otto F., Schmid P., Mackensen A., Wehr U., Seiz A., Braun M. et al. (1996) Phase II trial of intravenous endotoxin in patients with colorectal and non-small cell lung cancer. Eur. J. Cancer 32A: 1712-1718
-
(1996)
Eur. J. Cancer
, vol.32 A
, pp. 1712-1718
-
-
Otto, F.1
Schmid, P.2
Mackensen, A.3
Wehr, U.4
Seiz, A.5
Braun, M.6
-
59
-
-
0028949467
-
Angiogenesis in microvascular endothelial cells induced by glioma cells and inhibited by tumor necrosis factor in vitro
-
Niida H., Takeuchi S., Tanaka R. and Minakawa T. (1995) Angiogenesis in microvascular endothelial cells induced by glioma cells and inhibited by tumor necrosis factor in vitro. Neurol. Med. Chir. 35: 209-214
-
(1995)
Neurol. Med. Chir.
, vol.35
, pp. 209-214
-
-
Niida, H.1
Takeuchi, S.2
Tanaka, R.3
Minakawa, T.4
-
60
-
-
0028335120
-
Tumor necrosis factor alpha-induced angiogenesis depends on in situ platelet-activating factor biosynthesis
-
Montrucchio G., Lupia E., Battaglia E., Passerini G., Bussolino F., Emanuelli G. et al. (1994) Tumor necrosis factor alpha-induced angiogenesis depends on in situ platelet-activating factor biosynthesis. J. Exp. Med. 180: 377-382
-
(1994)
J. Exp. Med.
, vol.180
, pp. 377-382
-
-
Montrucchio, G.1
Lupia, E.2
Battaglia, E.3
Passerini, G.4
Bussolino, F.5
Emanuelli, G.6
-
61
-
-
0026348814
-
Angiogenesis and its inhibition: Potential new therapies in oncology and non-neoplastic diseases
-
Billington D. C. (1991) Angiogenesis and its inhibition: potential new therapies in oncology and non-neoplastic diseases. Drug Des. Discov. 8: 3-35
-
(1991)
Drug Des. Discov.
, vol.8
, pp. 3-35
-
-
Billington, D.C.1
-
63
-
-
0023137686
-
Tumor necrosis factor inhibits the proliferation of cultured capillary endothelial cells
-
Schweigerer L., Malerstein B. and Gospodarowicz D. (1987) Tumor necrosis factor inhibits the proliferation of cultured capillary endothelial cells. Biochem. Biophys. Res. Commun. 143: 997-1004
-
(1987)
Biochem. Biophys. Res. Commun.
, vol.143
, pp. 997-1004
-
-
Schweigerer, L.1
Malerstein, B.2
Gospodarowicz, D.3
-
64
-
-
0029670093
-
Cooperative effect of TNFalpha, bFGF and VEGF on the formation of tubular structures of human microvascular endothelial cells in a fibrin matrix. Role of urokinase activity
-
Koolwijk P., van Erck M. G., de Vree W. J., Vermeer M. A., Weich H. A., Hanemaaijer R. et al. (1996) Cooperative effect of TNFalpha, bFGF and VEGF on the formation of tubular structures of human microvascular endothelial cells in a fibrin matrix. Role of urokinase activity. J. Cell Biol. 132: 1177-1188
-
(1996)
J. Cell Biol.
, vol.132
, pp. 1177-1188
-
-
Koolwijk, P.1
Van Erck, M.G.2
De Vree, W.J.3
Vermeer, M.A.4
Weich, H.A.5
Hanemaaijer, R.6
-
65
-
-
0030017083
-
Downregulation of vascular endothelial growth factor receptors by tumor necrosis factor-alpha in cultured human vascular endothelial cells
-
Patterson C., Perrella M. A., Endege W. O., Yoshizumi M., Lee M. E. and Haber E. (1996) Downregulation of vascular endothelial growth factor receptors by tumor necrosis factor-alpha in cultured human vascular endothelial cells. J. Clin. Invest. 98: 490-496
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 490-496
-
-
Patterson, C.1
Perrella, M.A.2
Endege, W.O.3
Yoshizumi, M.4
Lee, M.E.5
Haber, E.6
-
66
-
-
0026568694
-
Dual role of tumor necrosis factor-alpha in angiogenesis
-
Fajardo L. F., Kwan H. H., Kowalski J., Prionas S. D. and Allison A. C. (1992) Dual role of tumor necrosis factor-alpha in angiogenesis. Am. J. Pathol. 140: 539-544
-
(1992)
Am. J. Pathol.
, vol.140
, pp. 539-544
-
-
Fajardo, L.F.1
Kwan, H.H.2
Kowalski, J.3
Prionas, S.D.4
Allison, A.C.5
-
67
-
-
0026332260
-
Macrophage-derived angiogenesis factors
-
Sunderkotter C., Goebeler M., Schulze-Osthoff K., Bhardwaj R. and Sorg C. (1991) Macrophage-derived angiogenesis factors. Pharmacol. Ther. 51: 195-216
-
(1991)
Pharmacol. Ther.
, vol.51
, pp. 195-216
-
-
Sunderkotter, C.1
Goebeler, M.2
Schulze-Osthoff, K.3
Bhardwaj, R.4
Sorg, C.5
-
68
-
-
0023192006
-
Macrophage-induced angiogenesis is mediated by tumour necrosis factor-alpha
-
Leibovich S. J., Polverini P. J., Shepard H. M., Wiseman D. M., Shively V. and Nuseir N. (1987) Macrophage-induced angiogenesis is mediated by tumour necrosis factor-alpha. Nature 329: 630-632
-
(1987)
Nature
, vol.329
, pp. 630-632
-
-
Leibovich, S.J.1
Polverini, P.J.2
Shepard, H.M.3
Wiseman, D.M.4
Shively, V.5
Nuseir, N.6
-
69
-
-
0023881273
-
Tumor necrosis factor stimulates proliferation of human osteosarcoma cells and accumulation of c-myc messenger RNA
-
Kirstein M. and Baglioni C. (1988) Tumor necrosis factor stimulates proliferation of human osteosarcoma cells and accumulation of c-myc messenger RNA. J. Cell Physiol. 134: 479-484
-
(1988)
J. Cell Physiol.
, vol.134
, pp. 479-484
-
-
Kirstein, M.1
Baglioni, C.2
-
70
-
-
0024334637
-
Tumor necrosis factor alpha stimulates the growth of the clonogenic cells of acute myeloblastic leukemia in synergy with granulocyte macrophage colony-stimulating factor
-
Hoang T., Levy B., Onetto N., Haman A. and Rodriguez-Cimadevilla J. C. (1989) Tumor necrosis factor alpha stimulates the growth of the clonogenic cells of acute myeloblastic leukemia in synergy with granulocyte macrophage colony-stimulating factor. J. Exp. Med. 170: 15-26
-
(1989)
J. Exp. Med.
, vol.170
, pp. 15-26
-
-
Hoang, T.1
Levy, B.2
Onetto, N.3
Haman, A.4
Rodriguez-Cimadevilla, J.C.5
-
71
-
-
0026583231
-
Stimulatory effect of tumor necrosis factor-alpha on the growth of CMK, a human megakaryoblastic leukemia cell line
-
Miura K., Teramura M., Hoshino S., Mizoguchi H. and Sato T. (1992) Stimulatory effect of tumor necrosis factor-alpha on the growth of CMK, a human megakaryoblastic leukemia cell line. Leuk. Res. 16: 281-285
-
(1992)
Leuk. Res.
, vol.16
, pp. 281-285
-
-
Miura, K.1
Teramura, M.2
Hoshino, S.3
Mizoguchi, H.4
Sato, T.5
-
72
-
-
0027274028
-
Tumor necrosis factor alpha as an autocrine and paracrine growth factor for ovarian cancer: Monokine induction of tumor cell proliferation and tumor necrosis factor alpha expression
-
Wu S., Boyer C. M., Whitaker R. S., Berchuck A., Wiener J. R., Weinberg J. B. et al. (1993) Tumor necrosis factor alpha as an autocrine and paracrine growth factor for ovarian cancer: monokine induction of tumor cell proliferation and tumor necrosis factor alpha expression. Cancer Res. 53: 1939-1944
-
(1993)
Cancer Res.
, vol.53
, pp. 1939-1944
-
-
Wu, S.1
Boyer, C.M.2
Whitaker, R.S.3
Berchuck, A.4
Wiener, J.R.5
Weinberg, J.B.6
-
73
-
-
0028987238
-
Interleukin 1 alpha and tumor necrosis factor alpha stimulate autocrine amphiregulin expression and proliferation of human papillomavirus-immortalized and carcinoma-derived cervical epithelial cells
-
USA
-
Woodworth C. D., McMullin E., Iglesias M. and Plowman G. D. (1995) Interleukin 1 alpha and tumor necrosis factor alpha stimulate autocrine amphiregulin expression and proliferation of human papillomavirus-immortalized and carcinoma-derived cervical epithelial cells. Proc. Natl. Acad. Sci. USA 92: 2840-2844
-
(1995)
Proc. Natl. Acad. Sci.
, vol.92
, pp. 2840-2844
-
-
Woodworth, C.D.1
McMullin, E.2
Iglesias, M.3
Plowman, G.D.4
-
74
-
-
0030723362
-
Tumor necrosis factor alpha modulates mitogen-activated protein kinase activity of epidermal growth factor-stimulated MCF-7 breast cancer cells
-
Flury N., Eppenberger U. and Mueller H. (1997) Tumor necrosis factor alpha modulates mitogen-activated protein kinase activity of epidermal growth factor-stimulated MCF-7 breast cancer cells. Eur. J. Biochem. 249: 421-426
-
(1997)
Eur. J. Biochem.
, vol.249
, pp. 421-426
-
-
Flury, N.1
Eppenberger, U.2
Mueller, H.3
-
75
-
-
0030974029
-
Tumor necrosis factor-alpha and interleukin-1 induce activation of MAP kinase and SAP kinase in human neuroma fibroblasts
-
Lu G., Beuerman R. W., Zhao S., Sun G., Nguyen D. H., Ma S. et al. (1997) Tumor necrosis factor-alpha and interleukin-1 induce activation of MAP kinase and SAP kinase in human neuroma fibroblasts. Neurochem. Int. 30: 401-410
-
(1997)
Neurochem. Int.
, vol.30
, pp. 401-410
-
-
Lu, G.1
Beuerman, R.W.2
Zhao, S.3
Sun, G.4
Nguyen, D.H.5
Ma, S.6
-
76
-
-
0027269738
-
The mitogenic response to tumor necrosis factor alpha requires c-Jun/AP-1
-
Brach M. A., Gruss H. J., Sott C. and Hermann F. (1993) The mitogenic response to tumor necrosis factor alpha requires c-Jun/AP-1. Mol. Cell. Biol. 13: 4284-4290
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 4284-4290
-
-
Brach, M.A.1
Gruss, H.J.2
Sott, C.3
Hermann, F.4
-
77
-
-
0026814183
-
Tumour necrosis factor: Roles in cancer pathophysiology
-
Malik S. T. (1992) Tumour necrosis factor: roles in cancer pathophysiology. Semin. Cancer Biol. 3: 27-33
-
(1992)
Semin. Cancer Biol.
, vol.3
, pp. 27-33
-
-
Malik, S.T.1
-
78
-
-
0022382737
-
Recombinant human tumor necrosis factor alpha: Effects on proliferation of normal and transformed cells in vivo
-
Sugerman B. J., Aggerwal B. B. and Hess P. E. (1985) Recombinant human tumor necrosis factor alpha: effects on proliferation of normal and transformed cells in vivo. Science 230: 943-945
-
(1985)
Science
, vol.230
, pp. 943-945
-
-
Sugerman, B.J.1
Aggerwal, B.B.2
Hess, P.E.3
-
79
-
-
0022633381
-
Recombinant tumor necosis factor: Its effect and its synergism with interferon gamma on a variety of normal and transformed human cell lines
-
Fransen L., Van der Heyden J., Ruysschart R. and Fiers W. (1986) Recombinant tumor necosis factor: its effect and its synergism with interferon gamma on a variety of normal and transformed human cell lines. Eur. J. Cancer Clin. Oncol. 22: 419-426
-
(1986)
Eur. J. Cancer Clin. Oncol.
, vol.22
, pp. 419-426
-
-
Fransen, L.1
Van Der Heyden, J.2
Ruysschart, R.3
Fiers, W.4
-
80
-
-
0023244682
-
The effect of recombinant human tumor necrosis factor on growth and macromolecular synthesis of human epithelial cells
-
Dealtry G. B., Naylor M. S., Fiers W. and Balkwill F. R. (1987) the effect of recombinant human tumor necrosis factor on growth and macromolecular synthesis of human epithelial cells. Exp. Cell Res. 170: 428-438
-
(1987)
Exp. Cell Res.
, vol.170
, pp. 428-438
-
-
Dealtry, G.B.1
Naylor, M.S.2
Fiers, W.3
Balkwill, F.R.4
-
81
-
-
0023489182
-
Induction of tumor necrosis factor expression and resistance in a human breast tumor cell line
-
USA
-
Spriggs D., Imamura K., Rodriguez C., Horiguchi C. and Kufwe D. W. (1987) Induction of tumor necrosis factor expression and resistance in a human breast tumor cell line. Proc. Natl. Acad. Sci. USA 84: 6563-6566
-
(1987)
Proc. Natl. Acad. Sci.
, vol.84
, pp. 6563-6566
-
-
Spriggs, D.1
Imamura, K.2
Rodriguez, C.3
Horiguchi, C.4
Kufwe, D.W.5
-
82
-
-
0023132911
-
Cytostatic and cytotoxic activity of tumor necrosis factor on human cancer cells
-
Ruggiero V., Latham K. and Baglioni C. (1987) Cytostatic and cytotoxic activity of tumor necrosis factor on human cancer cells. J. Immunol. 138: 1711-1717
-
(1987)
J. Immunol.
, vol.138
, pp. 1711-1717
-
-
Ruggiero, V.1
Latham, K.2
Baglioni, C.3
-
83
-
-
0024430790
-
A phase I trial of subcutaneously administered recombination tumor necrosis factor to patients with advanced malignancy
-
Zamkoff K. W., Newman N. B., Rudolph A. R., Young J. and Poiesz B. J. (1989) A phase I trial of subcutaneously administered recombination tumor necrosis factor to patients with advanced malignancy. J. Biol. Response Mod. 8: 539-552
-
(1989)
J. Biol. Response Mod.
, vol.8
, pp. 539-552
-
-
Zamkoff, K.W.1
Newman, N.B.2
Rudolph, A.R.3
Young, J.4
Poiesz, B.J.5
-
84
-
-
0027331526
-
Phase I clinical trial of recombinant human tumor necrosis factor in children with refractory solid tumors: A Pediatric Oncology Group study
-
Furman W. L., Strother D., McClain K., Bell B., Leventhal B. and Pratt C. B. (1993) Phase I clinical trial of recombinant human tumor necrosis factor in children with refractory solid tumors: a Pediatric Oncology Group study. J. Clin. Oncol. 11: 2205-2210
-
(1993)
J. Clin. Oncol.
, vol.11
, pp. 2205-2210
-
-
Furman, W.L.1
Strother, D.2
McClain, K.3
Bell, B.4
Leventhal, B.5
Pratt, C.B.6
-
85
-
-
0023684531
-
A phase I trial of intravenously-administered recombinant tumor necrosis factor-alpha in cancer patients
-
Feinberg B., Kurzrock R., Talpaz M., Blick M., Saks S. and Gutterman J. U. (1988) A phase I trial of intravenously-administered recombinant tumor necrosis factor-alpha in cancer patients. J. Clin. Oncol. 6: 1328-1334
-
(1988)
J. Clin. Oncol.
, vol.6
, pp. 1328-1334
-
-
Feinberg, B.1
Kurzrock, R.2
Talpaz, M.3
Blick, M.4
Saks, S.5
Gutterman, J.U.6
-
86
-
-
0023629556
-
Phase I clinical trial of recombinant human tumor necrosis factor
-
Creaven P. J., Plager J. E., Dupere S., Huben R. P., Takita H., Mittelman A. et al. (1987) Phase I clinical trial of recombinant human tumor necrosis factor. Cancer Chemother. Pharmacol. 20: 137-144
-
(1987)
Cancer Chemother. Pharmacol.
, vol.20
, pp. 137-144
-
-
Creaven, P.J.1
Plager, J.E.2
Dupere, S.3
Huben, R.P.4
Takita, H.5
Mittelman, A.6
-
87
-
-
0025799563
-
Phase I trial of recombinant human tumour necrosis factor alpha in patients with advanced malignancy
-
Gamm H., Lindemann A., Mertelsmann R. and Herrmann F. (1991) Phase I trial of recombinant human tumour necrosis factor alpha in patients with advanced malignancy. Eur. J. Cancer 27: 856-863
-
(1991)
Eur. J. Cancer
, vol.27
, pp. 856-863
-
-
Gamm, H.1
Lindemann, A.2
Mertelsmann, R.3
Herrmann, F.4
-
88
-
-
0023178374
-
Phase I study of recombinant tumor necrosis factor in cancer patients
-
Blick M., Sherwin S. A., Rosenblum M. and Gutterman J. (1987) Phase I study of recombinant tumor necrosis factor in cancer patients. Cancer Res. 47: 2986-2989
-
(1987)
Cancer Res.
, vol.47
, pp. 2986-2989
-
-
Blick, M.1
Sherwin, S.A.2
Rosenblum, M.3
Gutterman, J.4
-
89
-
-
0025777716
-
Biological and clinical effects of intravenous tumor necrosis factor-alpha administered three times weekly
-
Schiller J. H., Storer B. E., Witt P. L., Alberti D., Tombes M. B., Arzoomanian R. et al. (1991 ) Biological and clinical effects of intravenous tumor necrosis factor-alpha administered three times weekly. Cancer Res. 51: 1651-1658
-
(1991)
Cancer Res.
, vol.51
, pp. 1651-1658
-
-
Schiller, J.H.1
Storer, B.E.2
Witt, P.L.3
Alberti, D.4
Tombes, M.B.5
Arzoomanian, R.6
-
90
-
-
0025752916
-
Recombinant tumour necrosis factor alpha administered subcutaneously or intramuscularly for treatment of advanced malignant disease: A phase I trial
-
Aulitzky W. E., Tilg H., Gastl G., Mull R., Flener R., Vogel W. et al. (1991) Recombinant tumour necrosis factor alpha administered subcutaneously or intramuscularly for treatment of advanced malignant disease: a phase I trial. Eur. J. Cancer 27: 462-467
-
(1991)
Eur. J. Cancer
, vol.27
, pp. 462-467
-
-
Aulitzky, W.E.1
Tilg, H.2
Gastl, G.3
Mull, R.4
Flener, R.5
Vogel, W.6
-
91
-
-
0024387320
-
A phase I trial of recombinant human tumor necrosis factor and interferon-gamma: Effects of combination cytokine administration in vivo
-
Demetri G. D., Spriggs D. R., Sherman M. L., Arthur K. A., Imamura K. and Kufe D. W. (1989) A phase I trial of recombinant human tumor necrosis factor and interferon-gamma: effects of combination cytokine administration in vivo. J. Clin. Oncol. 7: 1545-1553
-
(1989)
J. Clin. Oncol.
, vol.7
, pp. 1545-1553
-
-
Demetri, G.D.1
Spriggs, D.R.2
Sherman, M.L.3
Arthur, K.A.4
Imamura, K.5
Kufe, D.W.6
-
92
-
-
0030810883
-
Phase I study combining tumor necrosis factor with interferon-alpha and interleukin-2
-
Eskander E. D., Harvey H. A., Givant E. and Lipton A. (1997) Phase I study combining tumor necrosis factor with interferon-alpha and interleukin-2. Am. J. Clin. Oncol. 20: 511-514
-
(1997)
Am. J. Clin. Oncol.
, vol.20
, pp. 511-514
-
-
Eskander, E.D.1
Harvey, H.A.2
Givant, E.3
Lipton, A.4
-
93
-
-
0022377333
-
Characterization of receptors for human tumor necrosis factor and their regulation by gamma-interferon
-
Aggarwal B. B., Eessalu T. E. and Hass P. E. (1985) Characterization of receptors for human tumor necrosis factor and their regulation by gamma-interferon. Nature 318: 665-667
-
(1985)
Nature
, vol.318
, pp. 665-667
-
-
Aggarwal, B.B.1
Eessalu, T.E.2
Hass, P.E.3
-
94
-
-
0024442327
-
Antitumor effect of natural human tumor necrosis factor-alpha and natural human interferon-alpha in combination against human cancer transplanted into nude mice
-
Naomoto Y., Tanaka N. and Orita K. (1989) Antitumor effect of natural human tumor necrosis factor-alpha and natural human interferon-alpha in combination against human cancer transplanted into nude mice. Acta Med. Okayama 43: 211-221
-
(1989)
Acta Med. Okayama
, vol.43
, pp. 211-221
-
-
Naomoto, Y.1
Tanaka, N.2
Orita, K.3
-
95
-
-
0024436117
-
Phase II clinical trial of high-dose recombinant human tumor necrosis factor
-
Lenk H., Tanneberger S., Muller U., Ebert J. and Shiga T. (1989) Phase II clinical trial of high-dose recombinant human tumor necrosis factor. Cancer Chemother. Pharmacol. 24: 391-392
-
(1989)
Cancer Chemother. Pharmacol.
, vol.24
, pp. 391-392
-
-
Lenk, H.1
Tanneberger, S.2
Muller, U.3
Ebert, J.4
Shiga, T.5
-
96
-
-
0024995936
-
A phase II trial of recombinant tumor necrosis factor in patients with advanced colorectal carcinoma
-
Kemeny N., Childs B., Larchian W., Rosado K. and Kelsen D. (1990) A phase II trial of recombinant tumor necrosis factor in patients with advanced colorectal carcinoma. Cancer 66: 659-663
-
(1990)
Cancer
, vol.66
, pp. 659-663
-
-
Kemeny, N.1
Childs, B.2
Larchian, W.3
Rosado, K.4
Kelsen, D.5
-
97
-
-
0025662031
-
A phase II trial of recombinant tumor necrosis factor in patients with metastatic colorectal adenocarcinoma: A Southwest Oncology Group study
-
Whitehead R. P., Fleming T., Macdonald J. S., Goodman P. J., Neefe J., Braun T. J. et al. (1990) A phase II trial of recombinant tumor necrosis factor in patients with metastatic colorectal adenocarcinoma: a Southwest Oncology Group study. J. Biol. Response Mod. 9: 588-591
-
(1990)
J. Biol. Response Mod.
, vol.9
, pp. 588-591
-
-
Whitehead, R.P.1
Fleming, T.2
Macdonald, J.S.3
Goodman, P.J.4
Neefe, J.5
Braun, T.J.6
-
98
-
-
0025948022
-
A phase II trial of recombinant tumor necrosis factor in patients with adenocarcinoma of the pancreas: A Southwest Oncology Group study
-
Brown T. D., Goodman P., Fleming T., Macdonald J. S., Hersh E. M. and Braun T. J. (1991) A phase II trial of recombinant tumor necrosis factor in patients with adenocarcinoma of the pancreas: a Southwest Oncology Group study. J. Immunother. 10: 376-378
-
(1991)
J. Immunother.
, vol.10
, pp. 376-378
-
-
Brown, T.D.1
Goodman, P.2
Fleming, T.3
Macdonald, J.S.4
Hersh, E.M.5
Braun, T.J.6
-
99
-
-
0026334942
-
A Southwest Oncology Group phase II trial of recombinant tumor necrosis factor in metastatic breast cancer
-
Budd G. T., Green S., Baker L. H., Hersh E. P., Weick J. K. and Osborne C. K. (1991) A Southwest Oncology Group phase II trial of recombinant tumor necrosis factor in metastatic breast cancer. Cancer 68: 1694-1695
-
(1991)
Cancer
, vol.68
, pp. 1694-1695
-
-
Budd, G.T.1
Green, S.2
Baker, L.H.3
Hersh, E.P.4
Weick, J.K.5
Osborne, C.K.6
-
100
-
-
0026535984
-
A Southwest Oncology Group phase II trial of recombinant tumor necrosis factor in metastatic breast cancer
-
Helson L. (1992) A Southwest Oncology Group phase II trial of recombinant tumor necrosis factor in metastatic breast cancer. Cancer 69: 2866
-
(1992)
Cancer
, vol.69
, pp. 2866
-
-
Helson, L.1
-
101
-
-
0026773669
-
Phase II trial of recombinant tumor necrosis factor in disseminated malignant melanoma
-
Feldman E. R., Creagan E. T., Schaid D. J. and Ahmann D. L. (1992) Phase II trial of recombinant tumor necrosis factor in disseminated malignant melanoma. Am. J. Clin. Oncol. 15: 256-259
-
(1992)
Am. J. Clin. Oncol.
, vol.15
, pp. 256-259
-
-
Feldman, E.R.1
Creagan, E.T.2
Schaid, D.J.3
Ahmann, D.L.4
-
102
-
-
0028309101
-
Isolated limb perfusion with high-dose tumor necrosis factor for extremity melanoma and sarcoma
-
Fraker D. L. and Alexander H. R. (1994) Isolated limb perfusion with high-dose tumor necrosis factor for extremity melanoma and sarcoma. Important Adv. Oncol. 179-192
-
(1994)
Important Adv. Oncol.
, pp. 179-192
-
-
Fraker, D.L.1
Alexander, H.R.2
-
103
-
-
0028329569
-
Isolated perfusion of the limb with high-dose tumour necrosis factor-alpha (TNF-alpha), interferon-gamma (IFN-gamma) and melphalan for melanoma stage III. Results of a multi-centre pilot study
-
Lienard D., Eggermont A. M., Schraffordt Koops H., Kroon B. B., Rosenkaimer F., Autier P. et al. (1994) Isolated perfusion of the limb with high-dose tumour necrosis factor-alpha (TNF-alpha), interferon-gamma (IFN-gamma) and melphalan for melanoma stage III. Results of a multi-centre pilot study. Melanoma Res. 4 (Suppl 1): 21-26
-
(1994)
Melanoma Res.
, vol.4
, Issue.SUPPL. 1
, pp. 21-26
-
-
Lienard, D.1
Eggermont, A.M.2
Schraffordt Koops, H.3
Kroon, B.B.4
Rosenkaimer, F.5
Autier, P.6
-
104
-
-
0028350841
-
The use of tumour necrosis factor (TNF) in isolated perfusion: Results and side effects. The NCI results
-
Fraker D. L. and Alexander H. R. (1994) The use of tumour necrosis factor (TNF) in isolated perfusion: results and side effects. The NCI results. Melanoma Res. 4 (Suppl 1): 27-29
-
(1994)
Melanoma Res.
, vol.4
, Issue.SUPPL. 1
, pp. 27-29
-
-
Fraker, D.L.1
Alexander, H.R.2
-
105
-
-
0028641633
-
Clinical experience with high-dose tumor necrosis factor alpha in regional therapy of advanced melanoma
-
Lejeune F., Lienard D., Eggermont A., Schraffordt Koops H., Kroon B., Gerain J. et al. (1994) Clinical experience with high-dose tumor necrosis factor alpha in regional therapy of advanced melanoma. Circ. Shock 43: 191-197
-
(1994)
Circ. Shock
, vol.43
, pp. 191-197
-
-
Lejeune, F.1
Lienard, D.2
Eggermont, A.3
Schraffordt Koops, H.4
Kroon, B.5
Gerain, J.6
-
106
-
-
0029258638
-
Administration of high-dose tumor necrosis factor alpha by isolation perfusion of the limbs. Rationale and results
-
Lejeune F., Lienard D., Eggermont A., Schraffordt Koops H., Rosenkaimer F., Gerain J. et al. (1995) Administration of high-dose tumor necrosis factor alpha by isolation perfusion of the limbs. Rationale and results. J. Infus. Chemother. 5: 73-81
-
(1995)
J. Infus. Chemother.
, vol.5
, pp. 73-81
-
-
Lejeune, F.1
Lienard, D.2
Eggermont, A.3
Schraffordt Koops, H.4
Rosenkaimer, F.5
Gerain, J.6
-
107
-
-
0029688952
-
Isolated perfusion of the kidney with tumor necrosis factor for localized renal-cell carcinoma
-
Walther M. M., Jennings S. B., Choyke P. L., Andrich M., Hurley K., Linehan W. M. et al. (1996) Isolated perfusion of the kidney with tumor necrosis factor for localized renal-cell carcinoma. World J. Urol. 14: S2-7
-
(1996)
World J. Urol.
, vol.14
-
-
Walther, M.M.1
Jennings, S.B.2
Choyke, P.L.3
Andrich, M.4
Hurley, K.5
Linehan, W.M.6
-
108
-
-
0030953617
-
Isolated hepatic perfusion in the pig with TNF-alpha with and without melphalan
-
Borel Rinkes I. H., de Vries M. R., Jonker A. M., Swaak T. J., Hack C. E., Nooyen P. T. et al. (1997) Isolated hepatic perfusion in the pig with TNF-alpha with and without melphalan. Br. J. Cancer 75: 1447-1453
-
(1997)
Br. J. Cancer
, vol.75
, pp. 1447-1453
-
-
Borel Rinkes, I.H.1
De Vries, M.R.2
Jonker, A.M.3
Swaak, T.J.4
Hack, C.E.5
Nooyen, P.T.6
-
109
-
-
0031945558
-
Delivery of anticancer drugs via isolated hepatic perfusion: A promising strategy in the treatment of irresectable liver metastases?
-
Vahrmeijer A. L., Van Der Eb M. M., Van Dierendonck J. H., Kuppen P. J. and Van De Velde C. J. (1998) Delivery of anticancer drugs via isolated hepatic perfusion: a promising strategy in the treatment of irresectable liver metastases? Semin. Surg. Oncol. 14: 262-268
-
(1998)
Semin. Surg. Oncol.
, vol.14
, pp. 262-268
-
-
Vahrmeijer, A.L.1
Van Der Eb, M.M.2
Van Dierendonck, J.H.3
Kuppen, P.J.4
Van De Velde, C.J.5
-
110
-
-
0345596439
-
Isolated hepatic perfusion with tumor necrosis factor and melphalan for unresectable cancers confined to the liver
-
Alexander H. R., Bartlett D. L., Libutti S. K., Fraker D. L., Moser T. and Rosenberg S. A. (1998) Isolated hepatic perfusion with tumor necrosis factor and melphalan for unresectable cancers confined to the liver. J. Clin. Oncol. 16: 1479-1489
-
(1998)
J. Clin. Oncol.
, vol.16
, pp. 1479-1489
-
-
Alexander, H.R.1
Bartlett, D.L.2
Libutti, S.K.3
Fraker, D.L.4
Moser, T.5
Rosenberg, S.A.6
-
111
-
-
0029958293
-
The success of TNF alpha in isolated limb perfusion for irresectable extremity soft tissue sarcomas, melanoma and carcinomas: Observations in patients and pre-clinical perfusion models
-
Eggermont A. M. (1996) The success of TNF alpha in isolated limb perfusion for irresectable extremity soft tissue sarcomas, melanoma and carcinomas: observations in patients and pre-clinical perfusion models. Gan To Kagaku Ryoho 23: 1357-1370
-
(1996)
Gan To Kagaku Ryoho
, vol.23
, pp. 1357-1370
-
-
Eggermont, A.M.1
-
112
-
-
0031983124
-
Clinical management and current research in isolated limb perfusion for sarcoma and melanoma
-
Hohenberger P. and Kettelhack C. (1998) Clinical management and current research in isolated limb perfusion for sarcoma and melanoma. Oncology 55: 89-102
-
(1998)
Oncology
, vol.55
, pp. 89-102
-
-
Hohenberger, P.1
Kettelhack, C.2
-
113
-
-
0029913929
-
Augmented antitumor effects of killer cells induced by tumor necrosis factor gene-transduced autologous tumor cells from gastrointestinal cancer patients
-
Sato Y., Koshita Y., Hirayama M., Matuyama T., Wakimoto H., Hamada H. et al. (1996) Augmented antitumor effects of killer cells induced by tumor necrosis factor gene-transduced autologous tumor cells from gastrointestinal cancer patients. Hum. Gene Ther. 7: 1895-1905
-
(1996)
Hum. Gene Ther.
, vol.7
, pp. 1895-1905
-
-
Sato, Y.1
Koshita, Y.2
Hirayama, M.3
Matuyama, T.4
Wakimoto, H.5
Hamada, H.6
-
114
-
-
0032443525
-
Establishment of a human fibroblast cell line producing tumor necrosis factor alpha (KMST-6 TNF) and growth inhibitory effects of its conditioned medium on malignant cells in culture
-
Fushimi K., Torigoe K., Yamauchi H., Furusako S., Kurimoto M. and Namba M. (1998) Establishment of a human fibroblast cell line producing tumor necrosis factor alpha (KMST-6 TNF) and growth inhibitory effects of its conditioned medium on malignant cells in culture. In Vitro Cell Dev. Biol. Anim. 34: 463-467
-
(1998)
In Vitro Cell Dev. Biol. Anim.
, vol.34
, pp. 463-467
-
-
Fushimi, K.1
Torigoe, K.2
Yamauchi, H.3
Furusako, S.4
Kurimoto, M.5
Namba, M.6
-
115
-
-
0031951530
-
Adenoviral TNF-alpha gene therapy and radiation damage tumor vasculature in a human malignant glioma xenograft
-
Staba M. J., Mauceri H. J., Kufe D. W., Hallahan D. E. and Weichselbaum R. R. (1998) Adenoviral TNF-alpha gene therapy and radiation damage tumor vasculature in a human malignant glioma xenograft. Gene Ther. 5: 293-300
-
(1998)
Gene Ther.
, vol.5
, pp. 293-300
-
-
Staba, M.J.1
Mauceri, H.J.2
Kufe, D.W.3
Hallahan, D.E.4
Weichselbaum, R.R.5
-
116
-
-
0032522817
-
An apoptosis-inducing gene therapy for pancreatic cancer with a combination of 55-kDa tumor necrosis factor (TNF) receptor gene transfection and mutein TNF administration
-
Sato T., Yamauchi N., Sasaki H., Takahashi M., Okamoto T., Sakamaki S. et al. (1998) An apoptosis-inducing gene therapy for pancreatic cancer with a combination of 55-kDa tumor necrosis factor (TNF) receptor gene transfection and mutein TNF administration. Cancer Res. 58: 1677-1683
-
(1998)
Cancer Res.
, vol.58
, pp. 1677-1683
-
-
Sato, T.1
Yamauchi, N.2
Sasaki, H.3
Takahashi, M.4
Okamoto, T.5
Sakamaki, S.6
-
117
-
-
0031908236
-
Tumour therapy in mice using adenovirus vectors expressing human TNFx
-
Marr R. A., Hitt M., Muller W. J., Gauldie J. and Graham F. L. (1998) Tumour therapy in mice using adenovirus vectors expressing human TNFx. Int. J. Oncol. 12: 509-515
-
(1998)
Int. J. Oncol.
, vol.12
, pp. 509-515
-
-
Marr, R.A.1
Hitt, M.2
Muller, W.J.3
Gauldie, J.4
Graham, F.L.5
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