Depression and dementia: Comorbidities, identification, and treatment

Journal of Geriatric Psychiatry and Neurology

Volumn 11, Issue 4, 1998, Pages 201-205

  Meyers, Barnett S ^a  

^a WEILL CORNELL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDEPRESSANT AGENT; CITALOPRAM; CLOMIPRAMINE; FLUOXETINE; IMIPRAMINE; MOCLOBEMIDE; PAROXETINE; PLACEBO; SEROTONIN UPTAKE INHIBITOR;

CAREGIVER; COGNITION; COGNITIVE DEFECT; COMORBIDITY; DEMENTIA; DEPRESSION; DIFFERENTIAL DIAGNOSIS; DISABILITY; HUMAN; MORTALITY; PHENOMENOLOGY; PRIORITY JOURNAL; REVIEW; SIDE EFFECT;

EID: 0032411788     PISSN: 08919887     EISSN: None     Source Type: Journal    
DOI: 10.1177/089198879901100406     Document Type: Review

References (65)

1. Burns A, Jacoby R, Levy R. Psychiatric phenomena in Alzheimer's disease, III: disorder of mood. Br J Psychiatry 1990; 157:81-86.
2. Merriam AE, Aronson MK, Gaston P, et al. The psychiatrie symptoms of Alzheimer's disease. J Am Geriatric Soc 1988; 35:7-12.
3. Wragg RE, Jeste DV. Overview of depression and psychosis in Alzheimer's disease. Am J Psychiatry 1989; 146:577-587.
4. Parmalee PA, Katz IR, Lawton MP. Depression among the institutionalized aged: assessment and prevalence estimation. J Gerontol Med Sei 1989; 44:M22-M29.
5. Pearson JL, Teri L, Reifler BV, et al. Functional status and cognitive impairment in Alzheimer's patients with and without depression. J Am Geriatr Soc 1989; 37:1117-1121.
6. Rovner BW, Broadhead J, Spencer M, et al. Depression and Alzheimer's disease. Am J Psychiatry 1989; 146:350-353.
7. Fitz AG, Teri L. Depression, cognition and functional ability in patients with Alzheimer's disease. J Am Geriatr Soc 1994; 42:186-191.
8. Hamilton M. A rating scale for depression. J Neural Neurosurg Psychiatry 1960; 23:56-62.
9. Steele C, Rovner B, Chase GA, et al. Psychiatric symptoms and nursing home placement of patients with Alzheimer's disease. Am J Psychiatry 1990; 147:1049-1051.
10. Fries BE, Mehr DR, Schneider D, et al. Mental dysfunction and resource use in nursing homes. Med Care 1993; 31: 898-920.
11. Rovner BW, German PS, Brant LJ, et al. Depression and mortality in nursing homes. JAMA 1991; 265:993-996.
12. Samuels SC, Katz IR, Parmalee PA, et al. Use of the Hamilton and Montgomery-Asberg Depression Scales in the institutional elderly: relationship to measures of cognitive impairment, disability, physical illness and mortality. In press.
13. Feinberg T, Goodman B. Affective illness, dementia and pseudodementia. J Clin Psychiatry 1984; 45:99-103.
14. Kiloh LG. Pseudo-dementia. Acta Psychiatr Scand 1961; 37:336-351.
15. Wells CE. Pseudodementia. Am J Psychiatry 1979; 136: 895-900.
16. Meyers BS. Adverse cognitive effects of tricyclic antidepressants in the treatment of geriatric depression: fact or fiction? In: Shamoian CA, ed. Psychopharmacological treatment complications in the elderly. Washington, DC: American Psychiatric Press, 1987:1-16.
17. Kramer-Ginsberg E, Greenwald BS, Aisen PS, et al. Hypochondriasis in the elderly depressed. J Am Geriatr Soc 1989; 37:507-510.
18. Folstein MF, Folstein SE, McHugh PR. Dementia syndrome of depression. In: Katzman R, Terry RD, Bick KL, eds. Alzheimer's disease: senile dementia and related disorders. New York: Haven Press, 1978.
19. Alexopoulos GS, Young RC, Lieberman KW, et al. Platelet MAO activity in geriatric patients with depression and dementia. Am J Psychiatry 1987; 144:1480-1483.
20. Krai V, Emory O. Long term follow-up of depressive pseudodementia. Can J Psychiatry 1989; 34:445-447.
21. Alexopoulos GS, Meyers BS, Young RC, et al. The course of geriatric depression with "reversible dementia": a controlled study. Am J Psychiatry 1993; 150:1693-1699.
22. Devanand DP, Sano M, Tang MX, et al. Depressed mood and the incidence of Alzheimer's disease in the elderly living in the community. Arch Gen Psychiatry 1996; 53:175-182.
23. Reding M, Haycox J, Blass J. Depression in patients referred to a dementia clinic: a three-year prospective study. Arch Neural 1985; 42:894-896.
24. Lawlor BA, Ryan TM, Schneidler J, et al. Clinical symptoms associated with age at onset in Alzheimer's disease. Arn J Psychiatry 1994; 151:1646-1649.
25. Miller NE. The measurement of mood in senile brain disease: examiner ratings and self-reports. In: Cole JO, Barnett JE, eds. Psychopathology in the aged. New York: Raven Press, 1980.
26. Lazarus LW, Newton N, Cohler B, et al. Frequency and presentation of depressive symptoms in patients with primary degenerative dementia. Am J Psychiatry 1987; 144:41-45.
27. Cummings JL, Mega M, Gray K, et al. The neuropsychiatrie inventory: comprehensive assessment of psychopathology in dementia. Neurology 1994; 44:2308-2314.
28. Mega MS, Cummings JL, Fiorello T, et al. The spectrum of behavioral changes in Alzheimer's disease. Neurology 1996; 46:130-135.
29. Weiner MF, Edland SD, Luszczynski H. Prevalence and incidence of major depression in Alzheimer's disease. Am J Psychiatry 1994; 151:1006-1009.
30. Devanand DP, Jacobs DM, Tang MX, et al. The course of psychopathologic features in mild to moderate Alzheimer's disease. ArcA Gen Psychiatry 1997; 54:257-263.
31. Reifler BV, Larson E, Teri L, et al. Dementia of the Alzheimer's type and depression. J Am Geriatr Soc 1986; 34:855-859.
32. Rovner BW, Broadhead J, Spencer M, et al. Depression and Alzheimer's disease. Am J Psychiatry 1989; 146:350-355.
33. Migliorelli R, Tesona Sabe L, Petracchi M, et al. Prevalence and correlates of dysthymia and major depression among patients with Alzheimer's disease. Am J Psychiatry 1995; 152:37-44.
34. Burke WJ, Rubin EH, Morris JC, et al. Symptoms of "depression" in dementia of the Alzheimer type. Alzheimer Dis Assoc Disord 1988; 2:356-362.
35. Weiner MF, Svetlik D, Risser RC. What depressive symptoms are reported in Alzheimer's patients? Int J Geriatr Psychiatry 1997; 12:648-652.
36. Logsdon RG, Teri L. Depression in Alzheimer's disease patients: caregivers as surrogate reporters. J Am Geriatr Soc 1995; 43: 150-155.
37. Folstein MF, Folstein SE, McHugh PR. "Mini-mental state," a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975; 12:189-198.
38. Greenwald BS, Kramer-Ginsberg E, Marin DB, et al. Dementia with coexistent major depression. Am J Psychiatry 1989; 146:1472-1478.
39. Zubenko GS, Rosen J, Sweet RA, et al. Impact of psychiatric hospitalization on behavioral complications of Alzheimer's disease. Am J Psychiatry 1992; 149:1484-1491.
40. Reynolds CR, Perel JM, Kupfer DJ, et al. Open-trial response to antidepressant treatment in elderly patients with mixed depression and cognitive impairment. J Psychiatr Res 1987; 21:111-122.
41. Reifler BV, Teri L, Raskind M, et al. Double-blind trial of imipramine in Alzheimer's disease patients with and without depression. Am J Psychiatry 1989; 146:45-49.
42. Mattis S. Dementia Rating Scale. Odessa, FL: Psychological Resources, 1988.
43. Petracca G, Teson A, Chemerinski E, et al. A double-blind placebo-controlled study of clomipramine in depressed patients with Alzheimer's disease. J Neuropsychiatry Clin Neurosci 1996; 8:270-275.
44. Roth M, Mountjoy CQ, Amrein R, et al. Moclobemide in elderly patients with cognitive decline and depression: an international double-blind, placebo-controlled trial. Br J Psychiatry 1996; 168:149-157.
45. Lundquist RS, Bemens A, Olsen CG. Comorbid disease in geriatric patients: dementia and depression. Am Fam Physician 1997; 55:2687-2694.
46. Porter RJ, O'Brien JT. SSRIs may well be best treatment for elderly depressed subjects [letter]. BMJ 1998; 316:631.
47. Newhouse PA. Use of serotonin selective reuptake inhibitors in geriatric depression. J Clin Psychiatry 1996; 57(suppl 5):12-22.
48. Kasper S, Heiden A. Do SSRIs differ in their antidepressant efficacy. Hum Psychopharmacol 1995; 10:3163-3172.
49. Nemeroff CB, DeVane CL, Pollock BG. Newer antidepressants and the cytochrome P450 system. Am J Psychiatry 1996; 153:311-320.
50. Sproule BA, et al. Selective serotonin reuptake inhibitors and CNS drug interactions. Clin Pharmacokinet 1997; 33:454-471.
51. Gram LF, Hansen MGJ, Sindrup STH, et al. Citalopram: interaction studies with levomepromazine, imipramine, and lithium. Ther Drug Monit 1993; 15:18-24.
52. Greenblatt DJ, von Moltke LL, Harmatz JS, Shader RI. Human cytochromes and some newer antidepressants: kinetics, metabolism, and drug interactions. Manuscript in preparation.
53. Gottfries CG, Karlsson I, Nyth AL. Treatment of depression in elderly patients with and without dementia disorders. Int Clin Psychopharmacol 1992; 6(suppl 5):55-64.
54. Gottfries CG. Scandinavian experience with citalopram in the elderly. Int Clin Psychopharmacol 1996; 11(suppl l):41-44.
55. Andersen G, Ingeman-Nielsen M, Vestergaard K, et al. Pathoanatomical correlation between post-stroke pathological crying and damage to brain areas involved in serotonergic transmission. Stroke 1994; 25:1050-1052.
56. Andersen G, Vestergaard K, Rils JO. Citalopram for poststroke pathological crying. Lancet 1993; 342:837-839.
57. Andersen G, Vestegaard K, Laruitzen L. Effective treatment of post-stroke depression with the selective serotonin reuptake inhibitor citalopram. Stroke 1994; 25:1099-1104.
58. Nyth AL, Gottfries CG. The clinical efficacy of citalopram in treatment of emotional disturbances in dementia disorders: a Nordic multicentre study. Br J Psychiatry 1990; 157:894-901.
59. Gottfries CG, Brane G, Gullberg B, et al. A new rating scale for dementia syndromes. Arch Gerontol Geriatr 1982; 1: 311-330.
60. Montgomery SA, Asberg M. A new depression scale designed to be sensitive to change. Br J Psychiatry 1979; 134:381-382.
61. Nyth AL, Gottfries CG, Lyby K, et al. A controlled multicenter clinical study of citalopram and placebo in elderly depressed patients with and without concomitant dementia. Acta Psychiatr Scand 1992; 86:138-145.
62. Ragneskog H, Eriksson S, Karlsson I, et al. Long-term treatment of elderly individuals with emotional disturbances: an open study with citalopram. Int Psychogeriatr 1996; 8:659-668.
63. Volicer L, Rheaume Y, Cyr D. Treatment of depression in advanced A Izheimer's disease using sertraline. J Geriatr Psychiatr Neural 1994; 7:227-229.
64. Kaplan EW. Retrospective review of the effects of sertraline on 32 outpatients with dementia [letter]. Am J Geriatr Psychiatry 1998; 6:184.
65. Katona CL, Hunter BN, Bray J. A double blind comparison of the efficacy and safety of paroxetine and imipramine in the treatment of depression with dementia. Int J Geriatr Psychiatry 1998; 13:100-108.