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Volumn 80, Issue 3, 1998, Pages 277-292

Immunocytokines: A promising approach to cancer immunotherapy

Author keywords

Immunocytokines; Immunotherapy; Interleukin 2; Monoclonal antibodies; Natural killer cells; T cells

Indexed keywords

CD8 ANTIGEN; CYTOKINE; INTERLEUKIN 2;

EID: 0032403828     PISSN: 01637258     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0163-7258(98)00033-3     Document Type: Review
Times cited : (86)

References (62)
  • 2
    • 0029890827 scopus 로고    scopus 로고
    • T-cell-mediated eradication of murine metastatic melanoma induced by targeted interleukin-2 therapy
    • a
    • Becker J.C., Pancook J.D., Gillies S.D., Furukawa K., Reisfeld R.A. T-cell-mediated eradication of murine metastatic melanoma induced by targeted interleukin-2 therapy. J. Exp. Med. 183:1996;2361-2366. a.
    • (1996) J. Exp. Med. , vol.183 , pp. 2361-2366
    • Becker, J.C.1    Pancook, J.D.2    Gillies, S.D.3    Furukawa, K.4    Reisfeld, R.A.5
  • 3
    • 0029836763 scopus 로고    scopus 로고
    • An antibody-interleukin-2 fusion protein overcomes tumor heterogeneity by induction of a cellular immune response
    • b
    • Becker J.C., Varki N.M., Gillies S.D., Furukawa K., Reisfeld R.A. An antibody-interleukin-2 fusion protein overcomes tumor heterogeneity by induction of a cellular immune response. Proc. Natl. Acad. Sci. USA. 93:1996;7826-7831. b.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 7826-7831
    • Becker, J.C.1    Varki, N.M.2    Gillies, S.D.3    Furukawa, K.4    Reisfeld, R.A.5
  • 4
    • 0030453784 scopus 로고    scopus 로고
    • Long-lived and transferable tumor immunity in mice after targeted interleukin-2 therapy
    • Becker J.C., Varki N.M., Gillies S.D., Furukawa K., Reisfeld R.A. Long-lived and transferable tumor immunity in mice after targeted interleukin-2 therapy. J. Clin. Invest. 98:1997;2801-2804.
    • (1997) J. Clin. Invest. , vol.98 , pp. 2801-2804
    • Becker, J.C.1    Varki, N.M.2    Gillies, S.D.3    Furukawa, K.4    Reisfeld, R.A.5
  • 6
    • 0027996540 scopus 로고
    • Idiotype-cytokine fusion proteins as cancer vaccines. Relative efficacy of IL-2, IL-4, and granulocyte-macrophage colony-stimulating factor
    • Chen T.T., Tao M.H., Levy R. Idiotype-cytokine fusion proteins as cancer vaccines. Relative efficacy of IL-2, IL-4, and granulocyte-macrophage colony-stimulating factor. J. Immunol. 153:1994;4775-4787.
    • (1994) J. Immunol. , vol.153 , pp. 4775-4787
    • Chen, T.T.1    Tao, M.H.2    Levy, R.3
  • 8
    • 0023137637 scopus 로고
    • Two new monoclonal antibodies, Lym-1 and Lym-2, reactive with human B-lymphocytes and derived tumors, with immunodiagnostic and immunotherapeutic potential
    • Epstein A.L., Marder R.J., Winter J.N., Stathopoulos E., Chen F.M., Parker J.W., Taylor C.R. Two new monoclonal antibodies, Lym-1 and Lym-2, reactive with human B-lymphocytes and derived tumors, with immunodiagnostic and immunotherapeutic potential. Cancer Res. 47:1987;830-840.
    • (1987) Cancer Res. , vol.47 , pp. 830-840
    • Epstein, A.L.1    Marder, R.J.2    Winter, J.N.3    Stathopoulos, E.4    Chen, F.M.5    Parker, J.W.6    Taylor, C.R.7
  • 10
    • 0025877853 scopus 로고
    • Genetic construction and characterization of a fusion protein consisting of a chimeric F(ab′) with specificity for carcinomas and human IL-2
    • Fell H.P., Gayle M.A., Grosmaire L., Ledbetter J.A. Genetic construction and characterization of a fusion protein consisting of a chimeric F(ab′) with specificity for carcinomas and human IL-2. J. Immunol. 146:1991;2446-2452.
    • (1991) J. Immunol. , vol.146 , pp. 2446-2452
    • Fell, H.P.1    Gayle, M.A.2    Grosmaire, L.3    Ledbetter, J.A.4
  • 12
    • 0025891798 scopus 로고
    • Expression of genetically engineered immunoconjugates of lymphotoxin and a chimeric anti-ganglioside GD2 antibody
    • Gillies S.D., Young D., Lo K.M., Foley S.F., Reisfeld R.A. Expression of genetically engineered immunoconjugates of lymphotoxin and a chimeric anti-ganglioside GD2 antibody. Hybridoma. 10:1991;347-356.
    • (1991) Hybridoma , vol.10 , pp. 347-356
    • Gillies, S.D.1    Young, D.2    Lo, K.M.3    Foley, S.F.4    Reisfeld, R.A.5
  • 13
    • 0026572996 scopus 로고
    • Antibody-targeted interleukin-2 stimulates T-cell killing of autologous tumor cells
    • Gillies S.D., Reilly E.B., Lo K.M., Reisfeld R.A. Antibody-targeted interleukin-2 stimulates T-cell killing of autologous tumor cells. Proc. Natl. Acad. Sci. USA. 89:1992;1428-1432.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 1428-1432
    • Gillies, S.D.1    Reilly, E.B.2    Lo, K.M.3    Reisfeld, R.A.4
  • 15
    • 0019951384 scopus 로고
    • Lymphokine-activated killer cell phenomenon. Lysis of natural killer-resistant fresh solid tumor cells by interleukin-2-activated autologous human peripheral blood lymphocytes
    • Grimm E.A., Mazumder A., Zhang H.Z., Rosenberg S.A. Lymphokine-activated killer cell phenomenon. Lysis of natural killer-resistant fresh solid tumor cells by interleukin-2-activated autologous human peripheral blood lymphocytes. J. Exp. Med. 155:1982;1823-1841.
    • (1982) J. Exp. Med. , vol.155 , pp. 1823-1841
    • Grimm, E.A.1    Mazumder, A.2    Zhang, H.Z.3    Rosenberg, S.A.4
  • 16
    • 0020594301 scopus 로고
    • Lymphokine-activated killer cell phenomenon. II. Precursor phenotype is serologically distinct from peripheral T lymphocytes, memory cytotoxic thymus-derived lymphocytes, and natural killer cells
    • Grimm E.A., Ramsey K.M., Mazumder A., Wilson D.J., Djeu J.Y., Rosenberg S.A. Lymphokine-activated killer cell phenomenon. II. Precursor phenotype is serologically distinct from peripheral T lymphocytes, memory cytotoxic thymus-derived lymphocytes, and natural killer cells. J. Exp. Med. 157:1983;884-897.
    • (1983) J. Exp. Med. , vol.157 , pp. 884-897
    • Grimm, E.A.1    Ramsey, K.M.2    Mazumder, A.3    Wilson, D.J.4    Djeu, J.Y.5    Rosenberg, S.A.6
  • 17
    • 0028865072 scopus 로고
    • The enigma of the natural killer cell
    • Gumperz J.E., Parham P. The enigma of the natural killer cell. Nature. 378:1995;245-248.
    • (1995) Nature , vol.378 , pp. 245-248
    • Gumperz, J.E.1    Parham, P.2
  • 20
    • 0025091247 scopus 로고
    • Augmentation of antibody-dependent cell-mediated cytotoxicity following in vivo therapy with recombinant interleukin-2
    • Hank J.A., Robinson R.R., Surfus J., Mueller B.M., Reisfeld R.A., Cheung N.K., Sondel P.M. Augmentation of antibody-dependent cell-mediated cytotoxicity following in vivo therapy with recombinant interleukin-2. Cancer Res. 50:1990;5234-5239.
    • (1990) Cancer Res. , vol.50 , pp. 5234-5239
    • Hank, J.A.1    Robinson, R.R.2    Surfus, J.3    Mueller, B.M.4    Reisfeld, R.A.5    Cheung, N.K.6    Sondel, P.M.7
  • 21
    • 0023024386 scopus 로고
    • Lymphokine-activated killer cells targeted by monoclonal antibodies to the disialogangliosides GD2 and GD3 specifically lyse human tumor cells of neuroectodermal origin
    • Honsik C.J., Jung G., Reisfeld R.A. Lymphokine-activated killer cells targeted by monoclonal antibodies to the disialogangliosides GD2 and GD3 specifically lyse human tumor cells of neuroectodermal origin. Proc. Natl. Acad. Sci. USA. 83:1986;7893-7897.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 7893-7897
    • Honsik, C.J.1    Jung, G.2    Reisfeld, R.A.3
  • 22
    • 0030974616 scopus 로고    scopus 로고
    • Chimeric CLL-1 antibody fusion proteins containing granulocyte-macrophage colony-stimulating factor or interleukin-2 with specificity for B-cell malignancies exhibit enhanced effector functions while retaining tumor targeting properties
    • Hornick J.L., Khawli L.A., Hu P., Lynch M., Anderson P.M., Epstein A.L. Chimeric CLL-1 antibody fusion proteins containing granulocyte-macrophage colony-stimulating factor or interleukin-2 with specificity for B-cell malignancies exhibit enhanced effector functions while retaining tumor targeting properties. Blood. 89:1997;4437-4447.
    • (1997) Blood , vol.89 , pp. 4437-4447
    • Hornick, J.L.1    Khawli, L.A.2    Hu, P.3    Lynch, M.4    Anderson, P.M.5    Epstein, A.L.6
  • 24
    • 0004712263 scopus 로고
    • Regression of cutaneous metastatic melanoma by intralesional injection with human monoclonal antibody to ganglioside GD2
    • Irie R.F., Morton D.L. Regression of cutaneous metastatic melanoma by intralesional injection with human monoclonal antibody to ganglioside GD2. Proc. Natl. Acad. Sci. USA. 83:1986;8694-8698.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 8694-8698
    • Irie, R.F.1    Morton, D.L.2
  • 26
    • 0032031429 scopus 로고    scopus 로고
    • Natural killer-cell-mediated eradication of neuroblastoma metastases to bone marrow by targeted interleukin-2 therapy
    • Lode H.N., Xiang R., Dreier T., Varki N.M., Gillies S.D., Reisfeld R.A. Natural killer-cell-mediated eradication of neuroblastoma metastases to bone marrow by targeted interleukin-2 therapy. Blood. 91:1998;1706-1715.
    • (1998) Blood , vol.91 , pp. 1706-1715
    • Lode, H.N.1    Xiang, R.2    Dreier, T.3    Varki, N.M.4    Gillies, S.D.5    Reisfeld, R.A.6
  • 27
    • 0027407531 scopus 로고
    • Interleukin-2 in cancer treatment: Disappointing or (still) promising? A review
    • Maas R.A., Dullens H.F., Den Otter W. Interleukin-2 in cancer treatment. disappointing or (still) promising? A review Cancer Immunol. Immunother. 36:1993;141-148.
    • (1993) Cancer Immunol. Immunother. , vol.36 , pp. 141-148
    • Maas, R.A.1    Dullens, H.F.2    Den Otter, W.3
  • 28
    • 0029076718 scopus 로고
    • Priming of tumor-specific T-cells in the draining lymph nodes after immunization with interleukin-2-secreting tumor cells: Three consecutive stages may be required for successful tumor vaccination
    • Maass G., Schmidt W., Berger M., Schilcher F., Koszik F., Schneeberger A., Stingl G., Birnstiel M.L., Schweighoffer T. Priming of tumor-specific T-cells in the draining lymph nodes after immunization with interleukin-2-secreting tumor cells. three consecutive stages may be required for successful tumor vaccination Proc. Natl. Acad. Sci. USA. 92:1995;5540-5544.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 5540-5544
    • Maass, G.1    Schmidt, W.2    Berger, M.3    Schilcher, F.4    Koszik, F.5    Schneeberger, A.6    Stingl, G.7    Birnstiel, M.L.8    Schweighoffer, T.9
  • 29
    • 0028127304 scopus 로고
    • Phase I clinical trial using escalating single-dose infusion of chimeric anti-CD20 monoclonal antibody (IDEC-C2B8) in patients with recurrent B-cell lymphoma
    • Maloney D.G., Liles T.M., Czerwinski D.K., Waldichuk C., Rosenberg J., Grillo-Lopez A., Levy R. Phase I clinical trial using escalating single-dose infusion of chimeric anti-CD20 monoclonal antibody (IDEC-C2B8) in patients with recurrent B-cell lymphoma. Blood. 84:1994;2457-2466.
    • (1994) Blood , vol.84 , pp. 2457-2466
    • Maloney, D.G.1    Liles, T.M.2    Czerwinski, D.K.3    Waldichuk, C.4    Rosenberg, J.5    Grillo-Lopez, A.6    Levy, R.7
  • 30
    • 0023662289 scopus 로고
    • The TGF-beta family of growth and differentiation factors
    • Massague J. The TGF-beta family of growth and differentiation factors. Cell. 49:1987;437-438.
    • (1987) Cell , vol.49 , pp. 437-438
    • Massague, J.1
  • 32
    • 0029003537 scopus 로고
    • Clinical strategies for the treatment of neuroblastoma
    • Niethammer D., Handgretinger R. Clinical strategies for the treatment of neuroblastoma. Eur. J. Cancer. 31:1995;568-571.
    • (1995) Eur. J. Cancer , vol.31 , pp. 568-571
    • Niethammer, D.1    Handgretinger, R.2
  • 33
    • 0030007139 scopus 로고    scopus 로고
    • Eradication of established hepatic human neuroblastoma metastases in mice with severe combined immunodeficiency by antibody-targeted interleukin-2
    • Pancook J.D., Becker J.C., Gillies S.D., Reisfeld R.A. Eradication of established hepatic human neuroblastoma metastases in mice with severe combined immunodeficiency by antibody-targeted interleukin-2. Cancer Immunol. Immunother. 42:1996;88-92.
    • (1996) Cancer Immunol. Immunother. , vol.42 , pp. 88-92
    • Pancook, J.D.1    Becker, J.C.2    Gillies, S.D.3    Reisfeld, R.A.4
  • 34
    • 0028908324 scopus 로고
    • Paracrine cytokine adjuvants in cancer immunotherapy
    • Pardoll D.M. Paracrine cytokine adjuvants in cancer immunotherapy. Annu. Rev. Immunol. 13:1995;399-415.
    • (1995) Annu. Rev. Immunol. , vol.13 , pp. 399-415
    • Pardoll, D.M.1
  • 35
    • 0027433607 scopus 로고
    • Is chronic graft versus host disease an autoimmune disease?
    • Parkman R. Is chronic graft versus host disease an autoimmune disease? Curr. Opin. Immunol. 5:1993;800-803.
    • (1993) Curr. Opin. Immunol. , vol.5 , pp. 800-803
    • Parkman, R.1
  • 36
    • 0030175534 scopus 로고    scopus 로고
    • Recognition events that inhibit and activate natural killer cells
    • Raulet D.H. Recognition events that inhibit and activate natural killer cells. Curr. Opin. Immunol. 8:1996;372-377.
    • (1996) Curr. Opin. Immunol. , vol.8 , pp. 372-377
    • Raulet, D.H.1
  • 37
    • 0029143210 scopus 로고
    • Natural killer cell receptors: The offs and ons of NK-cell recognition
    • Raulet D.H., Held W. Natural killer cell receptors. the offs and ons of NK-cell recognition Cell. 82:1995;697-700.
    • (1995) Cell , vol.82 , pp. 697-700
    • Raulet, D.H.1    Held, W.2
  • 39
    • 0030771674 scopus 로고    scopus 로고
    • Immunocytokines: A new approach to immunotherapy of melanoma
    • Reisfeld R.A., Becker J.C., Gillies S.D. Immunocytokines. a new approach to immunotherapy of melanoma Melanoma Res. 7:1997;99-106.
    • (1997) Melanoma Res. , vol.7 , pp. 99-106
    • Reisfeld, R.A.1    Becker, J.C.2    Gillies, S.D.3
  • 44
    • 0025745414 scopus 로고
    • Modulation of T-cell function by gliomas
    • Roszman T., Elliott L., Brooks W. Modulation of T-cell function by gliomas. Immunol. Today. 12:1991;370-374.
    • (1991) Immunol. Today , vol.12 , pp. 370-374
    • Roszman, T.1    Elliott, L.2    Brooks, W.3
  • 45
    • 0031025998 scopus 로고    scopus 로고
    • Gene therapy for cancer: What have we done and where are we going
    • Roth J.A., Cristiano R.J. Gene therapy for cancer. what have we done and where are we going J. Natl. Cancer Inst. 89:1997;21-39.
    • (1997) J. Natl. Cancer Inst. , vol.89 , pp. 21-39
    • Roth, J.A.1    Cristiano, R.J.2
  • 46
    • 0027230932 scopus 로고
    • Factors, including transforming growth factor beta, released in the glioblastoma residual cavity, impair activity of adherent lymphokine-activated killer cells
    • Ruffini P.A., Rivoltini L., Silvani A., Boiardi A., Parmiani G. Factors, including transforming growth factor beta, released in the glioblastoma residual cavity, impair activity of adherent lymphokine-activated killer cells. Cancer Immunol. Immunother. 36:1993;409-416.
    • (1993) Cancer Immunol. Immunother. , vol.36 , pp. 409-416
    • Ruffini, P.A.1    Rivoltini, L.2    Silvani, A.3    Boiardi, A.4    Parmiani, G.5
  • 47
    • 0028060152 scopus 로고
    • A recombinant antibody-interleukin-2 fusion protein suppresses growth of hepatic human neuroblastoma metastases in severe combined immunodeficiency mice
    • Sabzevari H., Gillies S.D., Mueller B.M., Pancook J.D., Reisfeld R.A. A recombinant antibody-interleukin-2 fusion protein suppresses growth of hepatic human neuroblastoma metastases in severe combined immunodeficiency mice. Proc. Natl. Acad. Sci. USA. 91:1994;9626-9630.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 9626-9630
    • Sabzevari, H.1    Gillies, S.D.2    Mueller, B.M.3    Pancook, J.D.4    Reisfeld, R.A.5
  • 49
    • 0030056468 scopus 로고    scopus 로고
    • Models of T-cell anergy: Is there a common molecular mechanism?
    • Schwartz R.H. Models of T-cell anergy. is there a common molecular mechanism? J. Exp. Med. 184:1996;1-8.
    • (1996) J. Exp. Med. , vol.184 , pp. 1-8
    • Schwartz, R.H.1
  • 50
    • 0027182101 scopus 로고
    • Pharmacologic prophylaxis of acute graft-versus-host disease after allogeneic marrow transplantation
    • Schwinghammer T.L., Bloom E.J. Pharmacologic prophylaxis of acute graft-versus-host disease after allogeneic marrow transplantation. Clin. Pharmacol. 12:1993;736-761.
    • (1993) Clin. Pharmacol. , vol.12 , pp. 736-761
    • Schwinghammer, T.L.1    Bloom, E.J.2
  • 51
    • 0023093343 scopus 로고
    • Antibody-dependent cellular cytotoxicity mediated by murine lymphocytes activated in recombinant interleukin-2
    • Shiloni E., Eisenthal A., Sachs D., Rosenberg S.A. Antibody-dependent cellular cytotoxicity mediated by murine lymphocytes activated in recombinant interleukin-2. J. Immunol. 138:1987;1992-1998.
    • (1987) J. Immunol. , vol.138 , pp. 1992-1998
    • Shiloni, E.1    Eisenthal, A.2    Sachs, D.3    Rosenberg, S.A.4
  • 52
    • 0003975514 scopus 로고
    • Jovanovich, H. B. (ed.) Academic Press, San Diego, California
    • Silverstein, A. M. (1988) A History of Immunology. Jovanovich, H. B. (ed.) Academic Press, San Diego, California.
    • (1988) A History of Immunology
    • Silverstein, A.M.1
  • 53
    • 0027510415 scopus 로고
    • Lowest dose interleukin-2 immunotherapy
    • Smith K.A. Lowest dose interleukin-2 immunotherapy. Blood. 81:1993;1414-1423.
    • (1993) Blood , vol.81 , pp. 1414-1423
    • Smith, K.A.1
  • 54
    • 0029385129 scopus 로고
    • Antigen-presenting cells. Professionals and amateurs
    • Sprent J. Antigen-presenting cells. Professionals and amateurs. Curr. Biol. 5:1995;1095-1097.
    • (1995) Curr. Biol. , vol.5 , pp. 1095-1097
    • Sprent, J.1
  • 55
    • 0031578047 scopus 로고    scopus 로고
    • Experts call for action to prevent colon cancer deaths by spurring screening awareness
    • Steimle S. Experts call for action to prevent colon cancer deaths by spurring screening awareness. J. Natl. Cancer Inst. 89:1997;415-416.
    • (1997) J. Natl. Cancer Inst. , vol.89 , pp. 415-416
    • Steimle, S.1
  • 56
    • 0027315755 scopus 로고
    • Idiotype/granulocyte-macrophage colony-stimulating factor fusion protein as a vaccine for B-cell lymphoma
    • Tao M.H., Levy R. Idiotype/granulocyte-macrophage colony-stimulating factor fusion protein as a vaccine for B-cell lymphoma. Nature. 362:1993;755-758.
    • (1993) Nature , vol.362 , pp. 755-758
    • Tao, M.H.1    Levy, R.2
  • 57
    • 0024516721 scopus 로고
    • Mechanism of interleukin-2 signaling: Mediation of different outcomes by a single receptor and transduction pathway
    • Tigges M.A., Casey L.S., Koshland M.E. Mechanism of interleukin-2 signaling. mediation of different outcomes by a single receptor and transduction pathway Science. 243:1989;781-786.
    • (1989) Science , vol.243 , pp. 781-786
    • Tigges, M.A.1    Casey, L.S.2    Koshland, M.E.3
  • 58
  • 59
    • 0010361996 scopus 로고    scopus 로고
    • The anti-idiotypic approach to active specific immunotherapy of malignant melanoma
    • Y. Shoenfeld, R.C. Kennedy, & S. Ferrone. New York: Elsevier Science B.V
    • Wang X., Desai S., Noronha E., Mittelman A., Ferrone S. The anti-idiotypic approach to active specific immunotherapy of malignant melanoma. Shoenfeld Y., Kennedy R.C., Ferrone S. Idiotypes in Medicine. Autoimmunity, Infection and Cancer:1997;523-536 Elsevier Science B.V, New York.
    • (1997) Idiotypes in Medicine: Autoimmunity, Infection and Cancer , pp. 523-536
    • Wang, X.1    Desai, S.2    Noronha, E.3    Mittelman, A.4    Ferrone, S.5
  • 60
    • 0025365189 scopus 로고
    • Human recombinant interleukin-2 as an experimental therapeutic
    • Winkelhake J.L., Gauny S.S. Human recombinant interleukin-2 as an experimental therapeutic. Pharmacol. Rev. 42:1990;1-28.
    • (1990) Pharmacol. Rev. , vol.42 , pp. 1-28
    • Winkelhake, J.L.1    Gauny, S.S.2


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