Selective labelling of 5-HT7 receptor recognition sites in rat brain using [3H]5-carboxamidotryptamine

Neuropharmacology

Volumn 37, Issue 12, 1998, Pages 1611-1619

  Stowe, Rebecca L ^a   Barnes, Nicholas M ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

5 HT7 receptor (rat); Pharmacological characterisation; Radioligand binding

Indexed keywords

1 METHYL 3 INDOLECARBOXYLIC ACID [1 [2 (METHYLSULFONYLAMINO)ETHYL] 4 PIPERIDINYLMETHYL] ESTER; 2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 4 IODO 2,5 DIMETHOXYAMPHETAMINE; 5 CARBAMOYLTRYPTAMINE; CLOZAPINE; KETANSERIN; METITEPINE; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; ONDANSETRON; PIMOZIDE; PINDOLOL; RITANSERIN; SEROTONIN; SEROTONIN RECEPTOR; SUMATRIPTAN;

ALTERNATIVE RNA SPLICING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN HOMOGENATE; CONTROLLED STUDY; LIGAND BINDING; MALE; NONHUMAN; PHARMACOLOGICAL PROCEDURES; PRIORITY JOURNAL; RADIOASSAY; RAT; RECEPTOR BINDING;

8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN; ANIMALS; BINDING, COMPETITIVE; BRAIN; CLOZAPINE; INDOLES; KINETICS; MALE; PINDOLOL; PIPERAZINES; PYRIDINES; RADIOLIGAND ASSAY; RATS; RATS, WISTAR; RECEPTORS, SEROTONIN; RECOMBINANT PROTEINS; SEROTONIN; SULFONAMIDES; TRITIUM;

EID: 0032403769     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(98)00117-8     Document Type: Article

References (29)

1. 7) positively linked to adenylate cyclase. Journal of Biological Chemistry. 268:1993;23422-23426.
2. Boess F.G., Martin I.L. Molecular biology of 5-HT receptors. Neuropharmacology. 33:1994;275-317.
3. 7 receptors. British Journal of Pharmacology. 117:1996;132P.
4. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilising the principal of protein dye binding. Analytical Biochemistry. 72:1976;248-254.
5. Castro E., Romon T., Castillo J., del Olmo E., Pazos A., del Arco C. Identification and characterisation of a new serotonergic recognition site with high affinity for 5-carboxamidotryptamine in mammalian brain. Journal of Neurochemistry. 69:1997;2123-2131.
6. 1A receptor antagonists: utility as research tools and therapeutic agents. TIPS. 14(12):1993;441-448.
7. 7 receptor antagonist. Journal of Medical Chemistry. 41:1998;655-657.
8. 1nonA-nonB receptors in rat hypothalamus? Molecular Pharmacology. 49:1996;556-559.
9. 7 receptor in rat brain. British Journal of Pharmacology. 117:1996;657-666.
10. 7) receptor isoforms in human and rat produced by alternative splicing: species differences due to altered intron-exon organization. Journal of Neurochemistry. 68:1997;1372-1381.
11. 1C receptor-mediated stimulation of inositol phosphate production in pig choroid plexus; a pharmacological characterisation. Naunyn-Schmiedeberg's Archiv fuer Pharmakologie. 339:1989;252-258.
12. Hoyer D., Clarke D.E., Fozard J.R., Hartig P.R., Martin G.R., Mylecharane E.J., Saxena P.R., Humphrey P.P.A. International union of pharmacology classification of receptors for 5-hydroxytryptamine (serotonin). Pharmacological Reviews. 46:1994;157-203.
13. 7(b)). British Journal of Pharmacology. 122:1997;126-132.
14. 7) implicated in the regulation of mammalian circadian rhythms. Neuron. 11:1993;449-458.
15. Meyerhof W., Obermuller F., Fehr S., Richter D. A novel rat serotonin receptor: primary structure, pharmacology, and expression pattern in distinct brain regions. DNA Cell Biology. 12:1993;401-409.
16. Monsma F.J., Shen Y., Ward R.P., Hamblin M.W., Sibley D.R. Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs. Molecular Pharmacology. 43:1993;320-327.
17. 7 receptor from Xenopus laevis. Receptors Channels. 3:1995;61-70.
18. Pazos A., Palacios J.M. Quantitative autoradiographic mapping of serotonin receptors in the rat brain. I. Serotonin-1 receptors. Brain Research. 346:1985;205-230.
19. 1D binding sites. European Journal of Pharmacology. 163:1989;133-136.
20. Plassat J.L., Amlaiky N., Hen R. Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase. Molecular Pharmacology. 44:1993;229-236.
21. Roth B.L., Craigo S.C., Choudhary M.S. et al. Binding of typical and atypical antipsychotic agents to 5-Hydroxytryptamine-6 and 5-Hydroxytryptamine-7 receptors. Journal of Pharmacology and Experimental Therapeutics. 268:1994;1403-1410.
22. 7) activating cAMP formation. Proceedings of the National Academy of Science (USA). 90:1993;8547-8551.
23. 7 serotonin receptor subtype. Journal of Biological Chemistry. 268:1993;18200-18204.
24. 7 receptor binding sites in rat hypothalamus: Sensitivity to chronic antidepressant treatment. Molecular Pharmacology. 47:1995;99-103.
25. 3H]5-CT binding in rat brain tissue. British Journal Of Pharmacology. 119:1996;366P.
26. 3H]5-CT binding in rat hypothalamus. British Journal Of Pharmacology. 123:1998;230P.
27. 7 receptors in guinea pig brain. British Journal of Pharmacology. 115:1995;107-116.
28. 7 receptor positively coupled to adenylyl cyclase. Journal of Neurochemistry. 63:1994;456-464.
29. 3H]5-carboxamidotryptamine binding sites in the guinea pig and rat brain. European Journal of Pharmacology. 283:1995;31-46.