Structure determination for octasaccharides derived from the carbohydrate-protein linkage region of chondroitin sulphate chains in the proteoglycan aggrecan from bovine articular cartilage

European Journal of Biochemistry

Volumn 258, Issue 2, 1998, Pages 669-676

  Huckerby, Thomas N ^a   Lauder, Robert M ^a   Nieduszynski, Ian A ^a  

^a LANCASTER UNIVERSITY   (United Kingdom)

Author keywords

Glycosaminoglycan; Linkage region; Sulphation

Indexed keywords

AGGRECAN; CHONDROITIN SULFATE; CORE PROTEIN; GLYCOSAMINOGLYCAN; PROTEOGLYCAN;

ANIMAL CELL; ANION EXCHANGE; ARTICLE; ARTICULAR CARTILAGE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PURIFICATION; PROTEIN STRUCTURE; PROTON NUCLEAR MAGNETIC RESONANCE;

AGGRECANS; ANIMALS; CARBOHYDRATE CONFORMATION; CARBOHYDRATE SEQUENCE; CARTILAGE, ARTICULAR; CATTLE; CHONDROITIN SULFATES; EXTRACELLULAR MATRIX PROTEINS; LECTINS, C-TYPE; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR SEQUENCE DATA; OLIGOSACCHARIDES; PROTEOGLYCANS; SEQUENCE ANALYSIS;

ANIMALIA; BOVINAE;

EID: 0032403008     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.1998.2580669.x     Document Type: Article

References (26)

1. Fransson, L. Å. (1987) Structure and function of cell-associated proteoglycans, Trends Biochem. Sci. 12, 406-411.
2. Sugahara, K., Tanaka, Y., Yamada, S., Seno, N., Kitagawa, H., Haslam, S. M., Morris, H. R. & Dell, A. (1996) Novel sulfated oligosaccharides containing 3-O-sulfated glucuronic-acid from king crab cartilage chondroitin sulfate-K-unexpected degradation by chondroitinase ABC, J. Biol. Chem. 271, 26745-26754.
3. Mourao, P. A. S., Pereira, M. S., Pavao, M. S. G., Mulloy, B., Tollefsen, D. M., Mowinckel, M. C. & Ahildgaard, U. (1996) Structure and anticoagulant activity of a fucosylated chondroitin sulfate from echinoderm - sulfated fucose branches on the polysaccharide account for its high anticoagulant action, J. Biol. Chem. 271. 23973-23984.
4. Plaas, A. H. K., Wong-Palms, S., Roughley, P. J., Midura, R. J. & Hascall. V. C. (1997) Chemical and immunological assay of the nonreducing terminal residues of chondroitin sulfate from human aggrecan, J. Biol. Chem. 272, 20603-20610.
5. Roden, L. (1980) Structure and metabolism of connective tissue proteoglycans, in The biochemistry of glysoproteins and proteoglycans (Lennarz, W. J., ed.) pp. 267-371. Plenum, New York.
6. Sugahara, K., Ohkita, Y., Shibata, Y., Yoshida, K. & Ikegami, A. (1995) Structural studies on the hexasaccharide alditols isolated from the carbohydrate-protein linkage region of dermatan sulfate proteoglycans of bovine aorta - demonstration of iduronic acidcontaining components. J. Biol. Chem. 270, 7204-7212.
7. Doege, K., Chen, X. C., Cornuet, P. K. & Hassell, J. (1997) Nonglycosaminoglycan bearing domains of perlecan and aggrecan influence the utilization of sites for heparan and chondroitin sulfate synthesis, Matrix Biol. 16, 211-221.
8. Zhang, L. J. & Esko, J. D. (1994) Amino-acid determinants that drive heparan-sulfate assembly in a proteoglycan, J. Biol. Chem. 269, 19295-19299.
9. Fritz. T. A., Lugemwa, F. N., Sarkar, A. K. & Esko, J. D. (1994) Biosynthesis of heparan-sulfate on beta-D-xylosides depends on aglycone structure, J. Biol. Chem. 269, 300-307.
10. Sarkar, A. K. & Esko, J. D. (1995) Synthesis and glycosaminoglycan priming activity of three disaccharides related to the linkage region tetrasaccharide of proteoglycans, Carbohydr. Res. 279, 161-171.
11. de Beer, T., Inui, A., Tsuda, H., Sugahara, K. & Vliegenthart, J. F. G. (1996) Polydispersity in sulfation profile of oligosaccharidealditols isolated from the protein-linkage region and the repeating disaccharide region of chondroitin 4-sulfate of bovine nasal septal cartilage. Eur. J. Biochem. 240, 789-797.
12. Sugahara, K., Ohi, Y., Harada, T., de Waard, P. & Vliegenthart J. F. G. (1992) Structural studies on sulfated oligosaccharides derived from the carbohydrate-protein linkage region of chondroitin 6-sulfate proteoglycans of shark cartilage. I. Six compounds containing O or 1 sulfate and/or phosphate residues, J. Biol. Chem. 276, 6027-6025.
13. Sugahara, K., Yamashina, I., de Waard, P., Van Halbeek, H. & Vliegenthart, J. F. G. (1988) Structural studies on sulfated glycopeptides from the carbohydrate-protein linkage region of chondroitin 4-sulfate proteoglycans of Swarm rat chondrosarchoma. Demonstration of the structure Gal(4-O-sulfate)β1-3Gal/β1-4Xylβ1-O-Ser, J. Biol. Chem. 263, 10 168-10 174.
14. de Waard, P., Vliegenthart, J. F. G., Harada, T. & Sugahara, K. (1992) Structural studies on sulfated oligosaccharides derived from the carbohydrate-protein linkage region of chondroitin-6-sulfate proteoglycans of shark cartilage. II. Seven compounds containing 2 or 3 sulfate residues, J. Biol. Chem. 267, 6036-6043.
15. Sugahara, K., Tsuda, H., Yoshida, K., Yamada, S., de Beer, T. & Vliegenthart, J. F. G. (1995) Structure determination of the octasaccharide and decasaccharide sequences isolated from the carbohydrate-protein linkage region of porcine intestinal heparin. J. Biol. Chem. 270, 22914-22923.
16. Dickenson, J. M., Huckerby, T. N. & Nieduszynski, I. A. (1990) Two linkage-region fragments isolated from skeletal keratan sulfate contain a sulfated N-acetylglucosamine residue, Biochem. J. 269, 55-59.
17. Carney, S. L. (1986) Proteoglycans, in Carbohydrate analysis: a practical approach (Chaplin, M. F. & Kennedy, J. F., eds) pp. 97-141, IRL Press. Oxford.
18. Heinegård, D. & Axelsson, I. (1977) Distribution of keratan sulfate in cartilage proteoglycans, J. Biol. Chem. 252, 1971-1979.
19. Thornton, D. J., Morris, H. G., Cockin, G. H., Huckerby, T. N. & Nieduszynski, I. A. (1989) Structural studies of 2 populations of keratan sulfate chains from mature bovine articular-cartilage. Glycoconjugate J. 6, 209-218.
20. Carlson, S. R., Sasaki, H. & Fukuda, M. (1986) Structural variations of O-linked oligosaccharides present in leukosialin isolated from erythroid, myeloid, and T-lymphoid cell lines, J. Biol. Chem. 261, 12787-12795.
21. Thornton, D. J., Morris, H. G., Cockin, G. H., Huckerby, T. N., Nieduszynski, I. A., Carlstedt, I., Hardingham, T. E. & Ratcliffe. A. (1989) Structural and immunological studies of keratan sulphates from mature bovine articular cartilage, Biochem. J. 260, 277-282.
22. Pons, J. L., Malliavin, T. E. & Delsuc, M. A. (1996) Gifa V4: a complete package for NMR dataset processing. J. Biomol. NMR 8, 445-452.
23. Cheng, F., Heinegård, D., Fransson, L. Å., Bayliss, M., Bielicki, J., Hopwood, J. & Yoshida, K. (1996) Variations in the chondroitin sulfate-protein linkage region of aggrecans from bovine nasal and human articular cartilages, J. Biol. Chem. 271, 28572-28580.
24. Shibata, S., Midura, R. J. & Hascall, V. C. (1992) Structural analysis of the linkage region oligosaccharides and unsaturated disaccharides from chondroitin sulfate using CarboPac PAl. J. Biol. Chem. 267. 6548-6555.
25. Hamai, A., Hashimoto, N., Mochizuki, H., Kato, F., Makiguchi, Y., Horie, K. & Suzuki, S. (1997) Two distinct chondroitin sulfate ABC lyases - an endoeliminase yielding tetrasaccharides and an exoeliminase preferentially acting on oligosaccharides. J. Biol. Chem. 272, 9123-9130.
26. de Waard, P., Vliegenthart, J. F. G., Harada, T. & Sugahara, K. (1992) Structural studies on sulfated oligosaccharides derived from the carbohydrate-protein linkage region of chondroitin-6-sulfate proteoglycans of shark cartilage. II. 7 compounds containing 2 or 3 sulfate residues. J. Biol. Chem. 267, 6036- 6043.